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Items: 17


Mitochondrial dysfunction generates a growth-restraining signal linked to pyruvate in Drosophila larvae.

George J, Tuomela T, Kemppainen E, Nurminen A, Braun S, Yalgin C, Jacobs HT.

Fly (Austin). 2019 Mar - Dec;13(1-4):12-28. doi: 10.1080/19336934.2019.1662266. Epub 2019 Sep 17.


Alternative oxidase confers nutritional limitation on Drosophila development.

Saari S, Kemppainen E, Tuomela T, Oliveira MT, Dufour E, Jacobs HT.

J Exp Zool A Ecol Integr Physiol. 2019 Jul;331(6):341-356. doi: 10.1002/jez.2274. Epub 2019 Jun 20.


Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells.

Toompuu M, Tuomela T, Laine P, Paulin L, Dufour E, Jacobs HT.

Nucleic Acids Res. 2018 Jun 1;46(10):5209-5226. doi: 10.1093/nar/gky159.


Correction: Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth.

Kemppainen E, George J, Garipler G, Tuomela T, Kiviranta E, Soga T, Dunn CD, Jacobs HT.

PLoS One. 2016 Mar 8;11(3):e0151421. doi: 10.1371/journal.pone.0151421. eCollection 2016. No abstract available.


Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth.

Kemppainen E, George J, Garipler G, Tuomela T, Kiviranta E, Soga T, Dunn CD, Jacobs HT.

PLoS One. 2016 Jan 26;11(1):e0145836. doi: 10.1371/journal.pone.0145836. eCollection 2016. Erratum in: PLoS One. 2016;11(3):e0151421.


β carbonic anhydrase is required for female fertility in Drosophila melanogaster.

Syrjänen L, Valanne S, Kuuslahti M, Tuomela T, Sriram A, Sanz A, Jacobs HT, Rämet M, Parkkila S.

Front Zool. 2015 Aug 22;12:19. doi: 10.1186/s12983-015-0111-3. eCollection 2015.


Ciona intestinalis NADH dehydrogenase NDX confers stress-resistance and extended lifespan on Drosophila.

Gospodaryov DV, Lushchak OV, Rovenko BM, Perkhulyn NV, Gerards M, Tuomela T, Jacobs HT.

Biochim Biophys Acta. 2014 Nov;1837(11):1861-1869. doi: 10.1016/j.bbabio.2014.08.001. Epub 2014 Aug 12.


Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease.

Vartiainen S, Chen S, George J, Tuomela T, Luoto KR, O'Dell KM, Jacobs HT.

Dis Model Mech. 2014 Jun;7(6):635-48. doi: 10.1242/dmm.016527. Epub 2014 May 8.


Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency.

Kemppainen KK, Rinne J, Sriram A, Lakanmaa M, Zeb A, Tuomela T, Popplestone A, Singh S, Sanz A, Rustin P, Jacobs HT.

Hum Mol Genet. 2014 Apr 15;23(8):2078-93. doi: 10.1093/hmg/ddt601. Epub 2013 Nov 29.


Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.

Sanz A, Soikkeli M, Portero-Otín M, Wilson A, Kemppainen E, McIlroy G, Ellilä S, Kemppainen KK, Tuomela T, Lakanmaa M, Kiviranta E, Stefanatos R, Dufour E, Hutz B, Naudí A, Jové M, Zeb A, Vartiainen S, Matsuno-Yagi A, Yagi T, Rustin P, Pamplona R, Jacobs HT.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9105-10. doi: 10.1073/pnas.0911539107. Epub 2010 Apr 30.


Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation.

Fernandez-Ayala DJ, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, Costa R, Tuomela T, Zeviani M, Chung J, O'Dell KM, Rustin P, Jacobs HT.

Cell Metab. 2009 May;9(5):449-60. doi: 10.1016/j.cmet.2009.03.004.


Epidermal growth factor in mice: changes during circadian and female reproductive cycles.

Tuomela T, Viinikka L, Perheentupa J.

Acta Endocrinol (Copenh). 1990 Dec;123(6):643-8.


Epidermal growth factor in mice: effects of estradiol, testosterone and dexamethasone.

Tuomela T, Miettinen P, Pesonen K, Viinikka L, Perheentupa J.

Acta Endocrinol (Copenh). 1990 Aug;123(2):211-7.


Estrogen-androgen antagonism in the regulation of epidermal growth factor in mouse submandibular salivary gland and kidneys.

Tuomela T, Miettinen P, Viinikka L, Perheentupa J.

Life Sci. 1990;47(21):1925-32.


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