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Items: 1 to 50 of 224

1.

A Cross-reactive Protein Vaccine Combined with PCV-13 Prevents Streptococcus pneumoniae- and Haemophilus influenzae-mediated Acute Otitis Media.

Rowe HM, Mann B, Iverson A, Poole A, Tuomanen E, Rosch JW.

Infect Immun. 2019 Jul 15. pii: IAI.00253-19. doi: 10.1128/IAI.00253-19. [Epub ahead of print]

PMID:
31308088
2.

Acute Bacterial Meningitis: Challenges to Better Antibiotic Therapy.

Kietzman C, Tuomanen E.

ACS Infect Dis. 2019 Jul 3. doi: 10.1021/acsinfecdis.9b00122. [Epub ahead of print]

PMID:
31268283
3.

Streptococcus pneumoniae: Invasion and Inflammation.

Loughran AJ, Orihuela CJ, Tuomanen EI.

Microbiol Spectr. 2019 Mar;7(2). doi: 10.1128/microbiolspec.GPP3-0004-2018. Review.

4.

IgG1+ B-cell immunity predates IgE responses in epicutaneous sensitization to foods.

Jiménez-Saiz R, Ellenbogen Y, Koenig JFE, Gordon ME, Walker TD, Rosace D, Spill P, Bruton K, Kong J, Monteiro K, Wen J, Tuomanen EI, Kolbeck R, Chu DK, Waserman S, Jordana M.

Allergy. 2019 Jan;74(1):165-175. doi: 10.1111/all.13481. Epub 2018 Oct 11.

PMID:
29790165
5.

Gut Microbiome Composition Predicts Infection Risk During Chemotherapy in Children With Acute Lymphoblastic Leukemia.

Hakim H, Dallas R, Wolf J, Tang L, Schultz-Cherry S, Darling V, Johnson C, Karlsson EA, Chang TC, Jeha S, Pui CH, Sun Y, Pounds S, Hayden RT, Tuomanen E, Rosch JW.

Clin Infect Dis. 2018 Aug 1;67(4):541-548. doi: 10.1093/cid/ciy153.

PMID:
29518185
6.

A Multicenter Consortium to Define the Epidemiology and Outcomes of Inpatient Respiratory Viral Infections in Pediatric Hematopoietic Stem Cell Transplant Recipients.

Fisher BT, Danziger-Isakov L, Sweet LR, Munoz FM, Maron G, Tuomanen E, Murray A, Englund JA, Dulek D, Halasa N, Green M, Michaels MG, Madan RP, Herold BC, Steinbach WJ.

J Pediatric Infect Dis Soc. 2018 Dec 3;7(4):275-282. doi: 10.1093/jpids/pix051.

PMID:
29106589
7.

A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice.

Karlsson EA, Meliopoulos VA, van de Velde NC, van de Velde LA, Mann B, Gao G, Rosch J, Tuomanen E, McCullers J, Vogel P, Schultz-Cherry S.

MBio. 2017 Sep 19;8(5). pii: e00889-17. doi: 10.1128/mBio.00889-17.

8.

Pneumococcal neuraminidase activates TGF-β signalling.

Gratz N, Loh LN, Mann B, Gao G, Carter R, Rosch J, Tuomanen EI.

Microbiology. 2017 Jul 28. doi: 10.1099/mic.0.000511. [Epub ahead of print]

9.

Preparation of Purified Gram-positive Bacterial Cell Wall and Detection in Placenta and Fetal Tissues.

Mann B, Loh LN, Gao G, Tuomanen E.

Bio Protoc. 2016 Dec 5;6(23). pii: e2037. doi: 10.21769/BioProtoc.2037.

10.

RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host.

Honsa ES, Cooper VS, Mhaissen MN, Frank M, Shaker J, Iverson A, Rubnitz J, Hayden RT, Lee RE, Rock CO, Tuomanen EI, Wolf J, Rosch JW.

MBio. 2017 Jan 3;8(1). pii: e02124-16. doi: 10.1128/mBio.02124-16.

11.
12.

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy.

Kamei A, Gao G, Neale G, Loh LN, Vogel P, Thomas PG, Tuomanen EI, Murray PJ.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6153-E6161. Epub 2016 Sep 26.

13.

Bacterial Peptidoglycan Traverses the Placenta to Induce Fetal Neuroproliferation and Aberrant Postnatal Behavior.

Humann J, Mann B, Gao G, Moresco P, Ramahi J, Loh LN, Farr A, Hu Y, Durick-Eder K, Fillon SA, Smeyne RJ, Tuomanen EI.

Cell Host Microbe. 2016 Jun 8;19(6):901. doi: 10.1016/j.chom.2016.05.017. No abstract available.

14.

Pneumococcal Surface Protein A Plays a Major Role in Streptococcus pneumoniae-Induced Immunosuppression.

Saumyaa, Pujanauski L, Colino J, Flora M, Torres RM, Tuomanen E, Snapper CM.

J Immunol. 2016 May 1;196(9):3677-85. doi: 10.4049/jimmunol.1502709. Epub 2016 Mar 30.

15.

Bacterial Peptidoglycan Traverses the Placenta to Induce Fetal Neuroproliferation and Aberrant Postnatal Behavior

Humann J, Mann B, Gao G, Moresco P, Ramahi J, Loh LN, Farr A, Hu Y, Durick-Eder K, Fillon SA, Smeyne RJ, Tuomanen EI.

Cell Host Microbe. 2016 Mar 9;19(3):388-99. doi: 10.1016/j.chom.2016.02.009. Erratum in: Cell Host Microbe. 2016 Jun 8;19(6):901.

16.

Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium.

Kietzman CC, Gao G, Mann B, Myers L, Tuomanen EI.

Nat Commun. 2016 Feb 29;7:10859. doi: 10.1038/ncomms10859.

17.

Unveiling Unexpected Immune Activities Induced by Your Pneumococcal Vaccine.

Hurwitz JL, Tuomanen E.

MBio. 2016 Feb 23;7(1):e00137-16. doi: 10.1128/mBio.00137-16.

18.

AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness.

Brown LR, Gunnell SM, Cassella AN, Keller LE, Scherkenbach LA, Mann B, Brown MW, Hill R, Fitzkee NC, Rosch JW, Tuomanen EI, Thornton JA.

PLoS One. 2016 Jan 11;11(1):e0146785. doi: 10.1371/journal.pone.0146785. eCollection 2016.

19.

Host-pathogen interactions in bacterial meningitis.

Doran KS, Fulde M, Gratz N, Kim BJ, Nau R, Prasadarao N, Schubert-Unkmeir A, Tuomanen EI, Valentin-Weigand P.

Acta Neuropathol. 2016 Feb;131(2):185-209. doi: 10.1007/s00401-015-1531-z. Epub 2016 Jan 7. Review.

20.

Blood borne: bacterial components in mother's blood influence fetal development.

Loughran AJ, Tuomanen EI.

Inflamm Cell Signal. 2016;3(4). pii: e1421. doi: 10.14800/ics.1421.

21.

Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection.

Chen A, Mann B, Gao G, Heath R, King J, Maissoneuve J, Alderson M, Tate A, Hollingshead SK, Tweten RK, Briles DE, Tuomanen EI, Paton JC.

Clin Vaccine Immunol. 2015 Oct;22(10):1079-89. doi: 10.1128/CVI.00293-15. Epub 2015 Aug 5.

22.

Correlation Between the Interval of Influenza Virus Infectivity and Results of Diagnostic Assays in a Ferret Model.

Inagaki K, Song MS, Crumpton JC, DeBeauchamp J, Jeevan T, Tuomanen EI, Webby RJ, Hakim H.

J Infect Dis. 2016 Feb 1;213(3):407-10. doi: 10.1093/infdis/jiv331. Epub 2015 Jun 11.

23.

Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster.

Valentino MD, McGuire AM, Rosch JW, Bispo PJ, Burnham C, Sanfilippo CM, Carter RA, Zegans ME, Beall B, Earl AM, Tuomanen EI, Morris TW, Haas W, Gilmore MS.

Nat Commun. 2014 Nov 12;5:5411. doi: 10.1038/ncomms6411.

24.

Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function.

Brown AO, Mann B, Gao G, Hankins JS, Humann J, Giardina J, Faverio P, Restrepo MI, Halade GV, Mortensen EM, Lindsey ML, Hanes M, Happel KI, Nelson S, Bagby GJ, Lorent JA, Cardinal P, Granados R, Esteban A, LeSaux CJ, Tuomanen EI, Orihuela CJ.

PLoS Pathog. 2014 Sep 18;10(9):e1004383. doi: 10.1371/journal.ppat.1004383. eCollection 2014 Sep.

25.

Genomic analyses of pneumococci from children with sickle cell disease expose host-specific bacterial adaptations and deficits in current interventions.

Carter R, Wolf J, van Opijnen T, Muller M, Obert C, Burnham C, Mann B, Li Y, Hayden RT, Pestina T, Persons D, Camilli A, Flynn PM, Tuomanen EI, Rosch JW.

Cell Host Microbe. 2014 May 14;15(5):587-599. doi: 10.1016/j.chom.2014.04.005.

26.

A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media.

Rosch JW, Iverson AR, Humann J, Mann B, Gao G, Vogel P, Mina M, Murrah KA, Perez AC, Edward Swords W, Tuomanen EI, McCullers JA.

EMBO Mol Med. 2014 Jan;6(1):141-54. doi: 10.1002/emmm.201202150.

27.

Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung.

LeMessurier KS, Häcker H, Chi L, Tuomanen E, Redecke V.

PLoS Pathog. 2013;9(11):e1003727. doi: 10.1371/journal.ppat.1003727. Epub 2013 Nov 7.

28.

Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein.

Mann B, Thornton J, Heath R, Wade KR, Tweten RK, Gao G, El Kasmi K, Jordan JB, Mitrea DM, Kriwacki R, Maisonneuve J, Alderson M, Tuomanen EI.

J Infect Dis. 2014 Apr 1;209(7):1116-25. doi: 10.1093/infdis/jit502. Epub 2013 Sep 16.

29.

Catecholamine norepinephrine diminishes lung epithelial cell adhesion of Streptococcus pneumoniae by binding iron.

Gonzales XF, Castillo-Rojas G, Castillo-Rodal AI, Tuomanen E, López-Vidal Y.

Microbiology. 2013 Nov;159(Pt 11):2333-41. doi: 10.1099/mic.0.065607-0. Epub 2013 Aug 20.

PMID:
23963302
30.

The pneumococcus: epidemiology, microbiology, and pathogenesis.

Henriques-Normark B, Tuomanen EI.

Cold Spring Harb Perspect Med. 2013 Jul 1;3(7). pii: a010215. doi: 10.1101/cshperspect.a010215. Review.

31.

Control of virulence by small RNAs in Streptococcus pneumoniae.

Mann B, van Opijnen T, Wang J, Obert C, Wang YD, Carter R, McGoldrick DJ, Ridout G, Camilli A, Tuomanen EI, Rosch JW.

PLoS Pathog. 2012;8(7):e1002788. doi: 10.1371/journal.ppat.1002788. Epub 2012 Jul 12.

32.

Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin.

Lebensburger JD, Howard T, Hu Y, Pestina TI, Gao G, Johnson M, Zakharenko SS, Ware RE, Tuomanen EI, Persons DA, Rosch JW.

Blood. 2012 Feb 23;119(8):1915-21. doi: 10.1182/blood-2011-08-374447. Epub 2011 Nov 30.

33.

Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza.

Karlström A, Heston SM, Boyd KL, Tuomanen EI, McCullers JA.

J Infect Dis. 2011 Nov;204(9):1358-66. doi: 10.1093/infdis/jir522. Epub 2011 Sep 7.

34.

PGRPs kill with an ancient weapon.

Kietzman C, Tuomanen E.

Nat Med. 2011 Jun;17(6):665-6. doi: 10.1038/nm0611-665. No abstract available.

PMID:
21647145
35.

The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis.

Garrison SP, Thornton JA, Häcker H, Webby R, Rehg JE, Parganas E, Zambetti GP, Tuomanen EI.

PLoS Pathog. 2010 Dec 23;6(12):e1001240. doi: 10.1371/journal.ppat.1001240.

36.

Inhibition of T cells provides protection against early invasive pneumococcal disease.

LeMessurier K, Häcker H, Tuomanen E, Redecke V.

Infect Immun. 2010 Dec;78(12):5287-94. doi: 10.1128/IAI.00431-10. Epub 2010 Sep 20.

37.

Pneumococcal pathogenesis: "innate invasion" yet organ-specific damage.

Thornton JA, Durick-Eder K, Tuomanen EI.

J Mol Med (Berl). 2010 Feb;88(2):103-7. doi: 10.1007/s00109-009-0578-5. Epub 2010 Feb 17. Review.

38.

Early biofilm formation on microtiter plates is not correlated with the invasive disease potential of Streptococcus pneumoniae.

Lizcano A, Chin T, Sauer K, Tuomanen EI, Orihuela CJ.

Microb Pathog. 2010 Mar-Apr;48(3-4):124-30. doi: 10.1016/j.micpath.2010.01.002. Epub 2010 Jan 22.

39.

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease.

Rosch JW, Boyd AR, Hinojosa E, Pestina T, Hu Y, Persons DA, Orihuela CJ, Tuomanen EI.

J Clin Invest. 2010 Feb;120(2):627-35. doi: 10.1172/JCI39843. Epub 2010 Jan 19.

40.

Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza.

Gaur AH, Bagga B, Barman S, Hayden R, Lamptey A, Hoffman JM, Bhojwani D, Flynn PM, Tuomanen E, Webby R.

N Engl J Med. 2010 Jan 7;362(1):88-9. doi: 10.1056/NEJMc0910893. Epub 2009 Dec 23. No abstract available.

PMID:
20032317
41.

Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma.

Li Z, Wang H, Xue L, Shin DM, Roopenian D, Xu W, Qi CF, Sangster MY, Orihuela CJ, Tuomanen E, Rehg JE, Cui X, Zhang Q, Morse HC 3rd, Morris SW.

Blood. 2009 Nov 5;114(19):4158-68. doi: 10.1182/blood-2008-12-192583. Epub 2009 Aug 20.

42.

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models.

Orihuela CJ, Mahdavi J, Thornton J, Mann B, Wooldridge KG, Abouseada N, Oldfield NJ, Self T, Ala'Aldeen DA, Tuomanen EI.

J Clin Invest. 2009 Jun;119(6):1638-46. doi: 10.1172/JCI36759. Epub 2009 May 11.

43.

Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniae.

Rosch JW, Gao G, Ridout G, Wang YD, Tuomanen EI.

Mol Microbiol. 2009 Apr;72(1):12-25. doi: 10.1111/j.1365-2958.2009.06638.x. Epub 2009 Feb 17.

44.

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.

El Kasmi KC, Qualls JE, Pesce JT, Smith AM, Thompson RW, Henao-Tamayo M, Basaraba RJ, König T, Schleicher U, Koo MS, Kaplan G, Fitzgerald KA, Tuomanen EI, Orme IM, Kanneganti TD, Bogdan C, Wynn TA, Murray PJ.

Nat Immunol. 2008 Dec;9(12):1399-406. doi: 10.1038/ni.1671. Epub 2008 Nov 2.

45.

Calcium efflux is essential for bacterial survival in the eukaryotic host.

Rosch JW, Sublett J, Gao G, Wang YD, Tuomanen EI.

Mol Microbiol. 2008 Oct;70(2):435-44. doi: 10.1111/j.1365-2958.2008.06425.x. Epub 2008 Aug 29.

46.

Cytokine secretion requires phosphatidylcholine synthesis.

Tian Y, Pate C, Andreolotti A, Wang L, Tuomanen E, Boyd K, Claro E, Jackowski S.

J Cell Biol. 2008 Jun 16;181(6):945-57. doi: 10.1083/jcb.200706152.

47.

The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls.

Moreira LO, El Kasmi KC, Smith AM, Finkelstein D, Fillon S, Kim YG, Núñez G, Tuomanen E, Murray PJ.

Cell Microbiol. 2008 Oct;10(10):2067-77. doi: 10.1111/j.1462-5822.2008.01189.x. Epub 2008 Jun 28.

48.

Convergence of regulatory networks on the pilus locus of Streptococcus pneumoniae.

Rosch JW, Mann B, Thornton J, Sublett J, Tuomanen E.

Infect Immun. 2008 Jul;76(7):3187-96. doi: 10.1128/IAI.00054-08. Epub 2008 Apr 28.

49.

A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.

Leary PJ, Rajasekaran S, Morrison RR, Tuomanen EI, Chin TK, Hofmann PA.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2775-84. doi: 10.1152/ajpheart.00269.2008. Epub 2008 Apr 25.

50.

Planning and implementation of an infection control training program for healthcare providers in Latin America.

Caniza MA, Maron G, McCullers J, Clara WA, Cedillos R, Dueñas L, Arnold S, Williams BF, Tuomanen EI.

Infect Control Hosp Epidemiol. 2007 Dec;28(12):1328-33. Epub 2007 Oct 22.

PMID:
17994511

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