Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 121

1.

Preferential adsorption to air-water interfaces: a novel cryoprotective mechanism for LEA proteins.

Yuen F, Watson M, Barker R, Grillo I, Heenan RK, Tunnacliffe A, Routh AF.

Biochem J. 2019 Apr 10;476(7):1121-1135. doi: 10.1042/BCJ20180901.

2.

Structural progression of amyloid-β Arctic mutant aggregation in cells revealed by multiparametric imaging.

Lu M, Williamson N, Mishra A, Michel CH, Kaminski CF, Tunnacliffe A, Kaminski Schierle GS.

J Biol Chem. 2019 Feb 1;294(5):1478-1487. doi: 10.1074/jbc.RA118.004511. Epub 2018 Nov 30.

3.

Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly.

Lu M, Banetta L, Young LJ, Smith EJ, Bates GP, Zaccone A, Kaminski Schierle GS, Tunnacliffe A, Kaminski CF.

J Biol Chem. 2019 Jan 4;294(1):257-268. doi: 10.1074/jbc.RA118.003500. Epub 2018 Nov 6.

4.

Comparative genomics of bdelloid rotifers: Insights from desiccating and nondesiccating species.

Nowell RW, Almeida P, Wilson CG, Smith TP, Fontaneto D, Crisp A, Micklem G, Tunnacliffe A, Boschetti C, Barraclough TG.

PLoS Biol. 2018 Apr 24;16(4):e2004830. doi: 10.1371/journal.pbio.2004830. eCollection 2018 Apr.

5.

Multiple genes contribute to anhydrobiosis (tolerance to extreme desiccation) in the nematode Panagrolaimus superbus.

Evangelista CCS, Guidelli GV, Borges G, Araujo TF, Souza TAJ, Neves UPDC, Tunnacliffe A, Pereira TC.

Genet Mol Biol. 2017 Oct-Dec;40(4):790-802. doi: 10.1590/1678-4685-GMB-2017-0030. Epub 2017 Nov 6.

6.

A functional difference between native and horizontally acquired genes in bdelloid rotifers.

Barbosa EG, Crisp A, Broadbent SE, Carrillo M, Boschetti C, Tunnacliffe A.

Gene. 2016 Sep 15;590(1):186-91. doi: 10.1016/j.gene.2016.06.019. Epub 2016 Jun 13.

PMID:
27312952
7.

Horizontal gene transfer in bdelloid rotifers is ancient, ongoing and more frequent in species from desiccating habitats.

Eyres I, Boschetti C, Crisp A, Smith TP, Fontaneto D, Tunnacliffe A, Barraclough TG.

BMC Biol. 2015 Nov 4;13:90. doi: 10.1186/s12915-015-0202-9.

8.

Determination of Water Content in Dehydrated Mammalian Cells Using Terahertz Pulsed Imaging: A Feasibility Study.

Chau DY, Dennis AR, Lin H, Zeitler JA, Tunnacliffe A.

Curr Pharm Biotechnol. 2015;17(2):200-7.

PMID:
26511980
9.

Long Term Aggresome Accumulation Leads to DNA Damage, p53-dependent Cell Cycle Arrest, and Steric Interference in Mitosis.

Lu M, Boschetti C, Tunnacliffe A.

J Biol Chem. 2015 Nov 13;290(46):27986-8000. doi: 10.1074/jbc.M115.676437. Epub 2015 Sep 25.

10.

A plant cell model of polyglutamine aggregation: Identification and characterisation of macromolecular and small-molecule anti-protein aggregation activity in vivo.

Liu G, Hu Y, Tunnacliffe A, Zheng Y.

J Biotechnol. 2015 Aug 10;207:39-46. doi: 10.1016/j.jbiotec.2015.05.003. Epub 2015 May 21.

PMID:
26003885
11.

Multiple horizontally acquired genes from fungal and prokaryotic donors encode cellulolytic enzymes in the bdelloid rotifer Adineta ricciae.

Szydlowski L, Boschetti C, Crisp A, Barbosa EG, Tunnacliffe A.

Gene. 2015 Jul 25;566(2):125-37. doi: 10.1016/j.gene.2015.04.007. Epub 2015 Apr 8.

PMID:
25863176
12.

Expression-level dependent perturbation of cell proteostasis and nuclear morphology by aggregation-prone polyglutamine proteins.

Lu M, Williamson N, Boschetti C, Ellis T, Yoshimi T, Tunnacliffe A.

Biotechnol Bioeng. 2015 Sep;112(9):1883-92. doi: 10.1002/bit.25606. Epub 2015 May 12.

PMID:
25854808
13.

Expression of multiple horizontally acquired genes is a hallmark of both vertebrate and invertebrate genomes.

Crisp A, Boschetti C, Perry M, Tunnacliffe A, Micklem G.

Genome Biol. 2015 Mar 13;16:50. doi: 10.1186/s13059-015-0607-3.

14.

Effects of secondary metabolite extract from Phomopsis occulta on β-amyloid aggregation.

Wu H, Zhang F, Williamson N, Jian J, Zhang L, Liang Z, Wang J, An L, Tunnacliffe A, Zheng Y.

PLoS One. 2014 Oct 2;9(10):e109438. doi: 10.1371/journal.pone.0109438. eCollection 2014. Erratum in: PLoS One. 2015;10(1):e0117542.

15.

Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology.

Michel CH, Kumar S, Pinotsi D, Tunnacliffe A, St George-Hyslop P, Mandelkow E, Mandelkow EM, Kaminski CF, Kaminski Schierle GS.

J Biol Chem. 2014 Jan 10;289(2):956-67. doi: 10.1074/jbc.M113.515445. Epub 2013 Nov 14.

16.

Critique of the use of fluorescence-based reporters in Escherichia coli as a screening tool for the identification of peptide inhibitors of Aβ42 aggregation.

Wright O, Zhang L, Liu Y, Yoshimi T, Zheng Y, Tunnacliffe A.

J Pept Sci. 2013 Feb;19(2):74-83. doi: 10.1002/psc.2474. Epub 2012 Dec 16.

PMID:
23255255
17.

Biochemical diversification through foreign gene expression in bdelloid rotifers.

Boschetti C, Carr A, Crisp A, Eyres I, Wang-Koh Y, Lubzens E, Barraclough TG, Micklem G, Tunnacliffe A.

PLoS Genet. 2012;8(11):e1003035. doi: 10.1371/journal.pgen.1003035. Epub 2012 Nov 15.

18.

MAPK phosphorylation is implicated in the adaptation to desiccation stress in nematodes.

Banton MC, Tunnacliffe A.

J Exp Biol. 2012 Dec 15;215(Pt 24):4288-98. doi: 10.1242/jeb.074799. Epub 2012 Sep 12.

19.

Multiple functionally divergent and conserved copies of alpha tubulin in bdelloid rotifers.

Eyres I, Frangedakis E, Fontaneto D, Herniou EA, Boschetti C, Carr A, Micklem G, Tunnacliffe A, Barraclough TG.

BMC Evol Biol. 2012 Aug 17;12:148. doi: 10.1186/1471-2148-12-148.

20.

Trafficking of bdelloid rotifer late embryogenesis abundant proteins.

Tripathi R, Boschetti C, McGee B, Tunnacliffe A.

J Exp Biol. 2012 Aug 15;215(Pt 16):2786-94. doi: 10.1242/jeb.071647.

21.

Complexity of the heat-soluble LEA proteome in Artemia species.

Warner AH, Chakrabortee S, Tunnacliffe A, Clegg JS.

Comp Biochem Physiol Part D Genomics Proteomics. 2012 Sep;7(3):260-7. doi: 10.1016/j.cbd.2012.04.002. Epub 2012 Apr 28.

PMID:
22595823
22.

Effects of Group 3 LEA protein model peptides on desiccation-induced protein aggregation.

Furuki T, Shimizu T, Chakrabortee S, Yamakawa K, Hatanaka R, Takahashi T, Kikawada T, Okuda T, Mihara H, Tunnacliffe A, Sakurai M.

Biochim Biophys Acta. 2012 Jul;1824(7):891-7. doi: 10.1016/j.bbapap.2012.04.013. Epub 2012 May 8.

PMID:
22579671
23.

Macromolecular and small-molecule modulation of intracellular Aβ42 aggregation and associated toxicity.

Chakrabortee S, Liu Y, Zhang L, Matthews HR, Zhang H, Pan N, Cheng CR, Guan SH, Guo DA, Huang Z, Zheng Y, Tunnacliffe A.

Biochem J. 2012 Mar 15;442(3):507-15. doi: 10.1042/BJ20111661.

PMID:
22150318
24.

Recombinant production of cathelicidin-derived antimicrobial peptides in Escherichia coli using an inducible autocleaving enzyme tag.

Wright O, Yoshimi T, Tunnacliffe A.

N Biotechnol. 2012 Feb 15;29(3):352-8. doi: 10.1016/j.nbt.2011.11.001. Epub 2011 Nov 9.

PMID:
22100429
25.

Intrinsically disordered proteins as molecular shields.

Chakrabortee S, Tripathi R, Watson M, Schierle GS, Kurniawan DP, Kaminski CF, Wise MJ, Tunnacliffe A.

Mol Biosyst. 2012 Jan;8(1):210-9. doi: 10.1039/c1mb05263b. Epub 2011 Sep 9.

26.

Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans.

Zhang H, Pan N, Xiong S, Zou S, Li H, Xiao L, Cao Z, Tunnacliffe A, Huang Z.

Biochem J. 2012 Jan 1;441(1):417-24. doi: 10.1042/BJ20110621.

PMID:
21892924
27.

Both plant and animal LEA proteins act as kinetic stabilisers of polyglutamine-dependent protein aggregation.

Liu Y, Chakrabortee S, Li R, Zheng Y, Tunnacliffe A.

FEBS Lett. 2011 Feb 18;585(4):630-4. doi: 10.1016/j.febslet.2011.01.020. Epub 2011 Jan 18.

28.

Foreign genes and novel hydrophilic protein genes participate in the desiccation response of the bdelloid rotifer Adineta ricciae.

Boschetti C, Pouchkina-Stantcheva N, Hoffmann P, Tunnacliffe A.

J Exp Biol. 2011 Jan 1;214(Pt 1):59-68. doi: 10.1242/jeb.050328.

29.

Phenomic and transcriptomic analyses reveal that autophagy plays a major role in desiccation tolerance in Saccharomyces cerevisiae.

Ratnakumar S, Hesketh A, Gkargkas K, Wilson M, Rash BM, Hayes A, Tunnacliffe A, Oliver SG.

Mol Biosyst. 2011 Jan;7(1):139-49. doi: 10.1039/c0mb00114g. Epub 2010 Oct 20.

PMID:
20963216
30.

Modeling anhydrobiosis: activation of the mitogen-activated protein kinase ERK by dehydration in both human cells and nematodes.

Huang Z, Banton MC, Tunnacliffe A.

J Exp Zool A Ecol Genet Physiol. 2010 Dec 1;313(10):660-70. doi: 10.1002/jez.637. Epub 2010 Sep 2.

PMID:
20814991
31.

Catalytic and chaperone-like functions in an intrinsically disordered protein associated with desiccation tolerance.

Chakrabortee S, Meersman F, Kaminski Schierle GS, Bertoncini CW, McGee B, Kaminski CF, Tunnacliffe A.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16084-9. doi: 10.1073/pnas.1006276107. Epub 2010 Aug 30.

32.

Rapid method for isolation of desiccation-tolerant strains and xeroprotectants.

Narváez-Reinaldo JJ, Barba I, González-López J, Tunnacliffe A, Manzanera M.

Appl Environ Microbiol. 2010 Aug;76(15):5254-62. doi: 10.1128/AEM.00855-10. Epub 2010 Jun 18.

33.

Ratiometric pH-dot ANSors.

Wang X, Boschetti C, Ruedas-Rama MJ, Tunnacliffe A, Hall EA.

Analyst. 2010 Jul;135(7):1585-91. doi: 10.1039/b922751b. Epub 2010 May 6.

PMID:
20449508
34.

Expression profiling and cross-species RNA interference (RNAi) of desiccation-induced transcripts in the anhydrobiotic nematode Aphelenchus avenae.

Reardon W, Chakrabortee S, Pereira TC, Tyson T, Banton MC, Dolan KM, Culleton BA, Wise MJ, Burnell AM, Tunnacliffe A.

BMC Mol Biol. 2010 Jan 19;11:6. doi: 10.1186/1471-2199-11-6.

35.

Bioinformatics and protein expression analyses implicate LEA proteins in the drought response of Collembola.

Bahrndorff S, Tunnacliffe A, Wise MJ, McGee B, Holmstrup M, Loeschcke V.

J Insect Physiol. 2009 Mar;55(3):210-7. doi: 10.1016/j.jinsphys.2008.11.010. Epub 2009 Jan 4.

PMID:
19100270
36.

Tolerance of plastic-encapsulated Pseudomonas putida KT2440 to chemical stress.

Vílchez S, Tunnacliffe A, Manzanera M.

Extremophiles. 2008 Mar;12(2):297-9. Epub 2007 Dec 21.

PMID:
18097632
37.

Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function.

Chakrabortee S, Boschetti C, Walton LJ, Sarkar S, Rubinsztein DC, Tunnacliffe A.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18073-8. Epub 2007 Nov 2.

38.

Functional divergence of former alleles in an ancient asexual invertebrate.

Pouchkina-Stantcheva NN, McGee BM, Boschetti C, Tolleter D, Chakrabortee S, Popova AV, Meersman F, Macherel D, Hincha DK, Tunnacliffe A.

Science. 2007 Oct 12;318(5848):268-71.

39.

Desiccation response of mammalian cells: anhydrosignaling.

Huang Z, Tunnacliffe A.

Methods Enzymol. 2007;428:269-77.

PMID:
17875423
40.

The continuing conundrum of the LEA proteins.

Tunnacliffe A, Wise MJ.

Naturwissenschaften. 2007 Oct;94(10):791-812. Epub 2007 May 4. Review.

PMID:
17479232
41.

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

Sarkar S, Davies JE, Huang Z, Tunnacliffe A, Rubinsztein DC.

J Biol Chem. 2007 Feb 23;282(8):5641-52. Epub 2006 Dec 20.

42.
43.

Dehydration-induced expression of LEA proteins in an anhydrobiotic chironomid.

Kikawada T, Nakahara Y, Kanamori Y, Iwata K, Watanabe M, McGee B, Tunnacliffe A, Okuda T.

Biochem Biophys Res Commun. 2006 Sep 15;348(1):56-61. Epub 2006 Jul 12.

PMID:
16875677
44.

Cryptobiosis, aging, and cancer: yin-yang balancing of signaling networks.

Huang Z, Tunnacliffe A.

Rejuvenation Res. 2006 Summer;9(2):292-6. Review.

PMID:
16706657
45.

Molecular anhydrobiology: identifying molecules implicated in invertebrate anhydrobiosis.

Goyal K, Walton LJ, Browne JA, Burnell AM, Tunnacliffe A.

Integr Comp Biol. 2005 Nov;45(5):702-9. doi: 10.1093/icb/45.5.702.

PMID:
21676820
46.

Gene induction by desiccation stress in human cell cultures.

Huang Z, Tunnacliffe A.

FEBS Lett. 2005 Sep 12;579(22):4973-7.

47.

Dehydration-regulated processing of late embryogenesis abundant protein in a desiccation-tolerant nematode.

Goyal K, Pinelli C, Maslen SL, Rastogi RK, Stephens E, Tunnacliffe A.

FEBS Lett. 2005 Aug 1;579(19):4093-8.

48.

Dehydration-induced tps gene transcripts from an anhydrobiotic nematode contain novel spliced leaders and encode atypical GT-20 family proteins.

Goyal K, Browne JA, Burnell AM, Tunnacliffe A.

Biochimie. 2005 Jun;87(6):565-74. Epub 2005 Feb 12.

PMID:
15935281
49.

Spliced leader RNA-mediated trans-splicing in phylum Rotifera.

Pouchkina-Stantcheva NN, Tunnacliffe A.

Mol Biol Evol. 2005 Jun;22(6):1482-9. Epub 2005 Mar 23.

PMID:
15788744
50.

LEA proteins prevent protein aggregation due to water stress.

Goyal K, Walton LJ, Tunnacliffe A.

Biochem J. 2005 May 15;388(Pt 1):151-7.

Supplemental Content

Loading ...
Support Center