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Items: 37

1.

Immunomodulatory Properties of DNA Hypomethylating Agents: Selecting the Optimal Epigenetic Partner for Cancer Immunotherapy.

Fazio C, Covre A, Cutaia O, Lofiego MF, Tunici P, Chiarucci C, Cannito S, Giacobini G, Lowder JN, Ferraldeschi R, Taverna P, Di Giacomo AM, Coral S, Maio M.

Front Pharmacol. 2018 Dec 7;9:1443. doi: 10.3389/fphar.2018.01443. eCollection 2018.

2.

Fifteenth Meeting of the Network Italiano per la Bioterapia dei Tumori (NIBIT) on Cancer Bio-Immunotherapy, Siena, Italy, October 5-7, 2017.

Maio M, Lofiego MF, Fazio C, Cannito S, Chiarucci C, Giacobini G, Valente M, Tunici P, Covre A, Russo V.

Cancer Immunol Immunother. 2019 Jan;68(1):151-158. doi: 10.1007/s00262-018-2222-0. Epub 2018 Aug 9. No abstract available.

PMID:
30094463
3.

Fourteenth Meeting of the Network Italiano per la Bioterapia dei Tumori (NIBIT) on Cancer Bio-Immunotherapy, Siena, Italy, October 13-15, 2016.

Russo V, Chiarucci C, Lofiego MF, Fazio C, Bertocci E, Cutaia O, Giacobini G, Lazzeri A, Lamboglia A, Altomonte M, Tunici P, Covre A, Maio M.

Cancer Immunol Immunother. 2018 Jun;67(6):1023-1030. doi: 10.1007/s00262-017-2078-8. Epub 2017 Oct 20. No abstract available.

PMID:
29058034
4.

Multimodal molecular imaging system for pathway-specific reporter gene expression.

Rossi M, Massai L, Diamanti D, Fiengo P, De Rosa A, Magrini R, Magnoni L, Chellini S, Coniglio S, Diodato E, Pilli E, Caradonna NP, Sardone G, Monti M, Roggeri R, Lionetti V, Recchia F, Tunici P, Valensin S, Scali C, Pollio G, Porcari V.

Eur J Pharm Sci. 2016 Apr 30;86:136-42. doi: 10.1016/j.ejps.2016.03.006. Epub 2016 Mar 14.

PMID:
26987608
5.

Structure-activity relationship and properties optimization of a series of quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway.

Nencini A, Pratelli C, Quinn JM, Salerno M, Tunici P, De Robertis A, Valensin S, Mennillo F, Rossi M, Bakker A, Benicchi T, Cappelli F, Turlizzi E, Nibbio M, Caradonna NP, Zanelli U, Andreini M, Magnani M, Varrone M.

Eur J Med Chem. 2015 May 5;95:526-45. doi: 10.1016/j.ejmech.2015.03.055. Epub 2015 Mar 25.

PMID:
25847770
6.

Human Sarcoma growth is sensitive to small-molecule mediated AXIN stabilization.

De Robertis A, Mennillo F, Rossi M, Valensin S, Tunici P, Mori E, Caradonna N, Varrone M, Salerno M.

PLoS One. 2014 May 19;9(5):e97847. doi: 10.1371/journal.pone.0097847. eCollection 2014.

7.

Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts.

Hermann PC, Trabulo SM, Sainz B Jr, Balic A, Garcia E, Hahn SA, Vandana M, Sahoo SK, Tunici P, Bakker A, Hidalgo M, Heeschen C.

PLoS One. 2013 Jun 18;8(6):e66371. doi: 10.1371/journal.pone.0066371. Print 2013.

8.

Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells.

De Robertis A, Valensin S, Rossi M, Tunici P, Verani M, De Rosa A, Giordano C, Varrone M, Nencini A, Pratelli C, Benicchi T, Bakker A, Hill J, Sangthongpitag K, Pendharkar V, Liu B, Ng FM, Then SW, Jing Tai S, Cheong SM, He X, Caricasole A, Salerno M.

Mol Cancer Ther. 2013 Jul;12(7):1180-9. doi: 10.1158/1535-7163.MCT-12-1176-T. Epub 2013 Apr 25.

9.

A radial glia gene marker, fatty acid binding protein 7 (FABP7), is involved in proliferation and invasion of glioblastoma cells.

De Rosa A, Pellegatta S, Rossi M, Tunici P, Magnoni L, Speranza MC, Malusa F, Miragliotta V, Mori E, Finocchiaro G, Bakker A.

PLoS One. 2012;7(12):e52113. doi: 10.1371/journal.pone.0052113. Epub 2012 Dec 21.

10.

In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines.

Ferruzzi P, Mennillo F, De Rosa A, Giordano C, Rossi M, Benedetti G, Magrini R, Pericot Mohr Gl, Miragliotta V, Magnoni L, Mori E, Thomas R, Tunici P, Bakker A.

Int J Cancer. 2012 Jul 15;131(2):E33-44. doi: 10.1002/ijc.27349. Epub 2012 Jan 31.

11.

Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells.

Gaviraghi M, Tunici P, Valensin S, Rossi M, Giordano C, Magnoni L, Dandrea M, Montagna L, Ritelli R, Scarpa A, Bakker A.

Biosci Rep. 2011 Feb;31(1):45-55. doi: 10.1042/BSR20100018.

12.

Pituitary adenoma stem cells.

Tunici P, Yu JS.

Methods Mol Biol. 2009;568:195-201. doi: 10.1007/978-1-59745-280-9_12.

PMID:
19582428
13.

Isolation of tumour stem-like cells from benign tumours.

Xu Q, Yuan X, Tunici P, Liu G, Fan X, Xu M, Hu J, Hwang JY, Farkas DL, Black KL, Yu JS.

Br J Cancer. 2009 Jul 21;101(2):303-11. doi: 10.1038/sj.bjc.6605142. Epub 2009 Jun 30.

14.

High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray.

Yin D, Ogawa S, Kawamata N, Tunici P, Finocchiaro G, Eoli M, Ruckert C, Huynh T, Liu G, Kato M, Sanada M, Jauch A, Dugas M, Black KL, Koeffler HP.

Mol Cancer Res. 2009 May;7(5):665-77. doi: 10.1158/1541-7786.MCR-08-0270. Epub 2009 May 12.

15.

How to achieve confidence in drug discovery and development: managing risk (from a reductionist to a holistic approach).

Bakker A, Caricasole A, Gaviraghi G, Pollio G, Robertson G, Terstappen GC, Salerno M, Tunici P.

ChemMedChem. 2009 Jun;4(6):923-33. doi: 10.1002/cmdc.200900056.

PMID:
19434656
16.

The potential of stem cells for the treatment of brain tumors and globoid cell leukodystrophy.

Tunici P, Pellegatta S, Finocchiaro G.

Cytotechnology. 2003 Mar;41(2-3):93-101. doi: 10.1023/A:1024818621377.

17.

A role for the transcription factor HEY1 in glioblastoma.

Hulleman E, Quarto M, Vernell R, Masserdotti G, Colli E, Kros JM, Levi D, Gaetani P, Tunici P, Finocchiaro G, Baena RR, Capra M, Helin K.

J Cell Mol Med. 2009 Jan;13(1):136-46. doi: 10.1111/j.1582-4934.2008.00307.x. Epub 2008 Mar 17.

18.

Spheres isolated from 9L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells.

Ghods AJ, Irvin D, Liu G, Yuan X, Abdulkadir IR, Tunici P, Konda B, Wachsmann-Hogiu S, Black KL, Yu JS.

Stem Cells. 2007 Jul;25(7):1645-53. Epub 2007 Apr 5.

19.

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma.

Liu G, Yuan X, Zeng Z, Tunici P, Ng H, Abdulkadir IR, Lu L, Irvin D, Black KL, Yu JS.

Mol Cancer. 2006 Dec 2;5:67.

20.

Brain tumor stem cells: new targets for clinical treatments?

Tunici P, Irvin D, Liu G, Yuan X, Zhaohui Z, Ng H, Yu JS.

Neurosurg Focus. 2006 Apr 15;20(4):E27. Review.

PMID:
16709033
21.

Brain engraftment and therapeutic potential of stem/progenitor cells derived from mouse skin.

Tunici P, Bulte JW, Bruzzone MG, Poliani PL, Cajola L, Grisoli M, Douglas T, Finocchiaro G.

J Gene Med. 2006 Apr;8(4):506-13.

PMID:
16389624
22.

The therapeutic potential of neural stem/progenitor cells in murine globoid cell leukodystrophy is conditioned by macrophage/microglia activation.

Pellegatta S, Tunici P, Poliani PL, Dolcetta D, Cajola L, Colombelli C, Ciusani E, Di Donato S, Finocchiaro G.

Neurobiol Dis. 2006 Feb;21(2):314-23. Epub 2005 Sep 30.

PMID:
16199167
23.

Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma.

Tunici P, Bissola L, Lualdi E, Pollo B, Cajola L, Broggi G, Sozzi G, Finocchiaro G.

Mol Cancer. 2004 Oct 6;3:25.

24.

Dexamethasone inhibits the anti-tumor effect of interleukin 4 on rat experimental gliomas.

Benedetti S, Pirola B, Poliani PL, Cajola L, Pollo B, Bagnati R, Magrassi L, Tunici P, Finocchiaro G.

Gene Ther. 2003 Jan;10(2):188-92.

PMID:
12571648
25.

Mxi1 inhibits the proliferation of U87 glioma cells through down-regulation of cyclin B1 gene expression.

Manni I, Tunici P, Cirenei N, Albarosa R, Colombo BM, Roz L, Sacchi A, Piaggio G, Finocchiaro G.

Br J Cancer. 2002 Feb 1;86(3):477-84.

26.

Gene therapy of glioblastomas: from suicide to homicide.

Tunici P, Gianni D, Finocchiaro G.

Prog Brain Res. 2001;132:711-9. Review. No abstract available.

PMID:
11545030
27.

In vivo modulation of 73 kDa heat shock cognate and 78 kDa glucose-regulating protein gene expression in rat liver and brain by ethanol.

Tunici P, Schiaffonati L, Rabellotti E, Tiberio L, Perin A, Sessa A.

Alcohol Clin Exp Res. 1999 Dec;23(12):1861-7.

PMID:
10630603
28.

Polyamine oxidase and tissue transglutaminase activation in rat small intestine by polyamines.

Tunici P, Sessa A, Rabellotti E, Grant G, Bardocz S, Perin A.

Biochim Biophys Acta. 1999 Aug 5;1428(2-3):219-24.

PMID:
10434039
29.

Distribution and activity of transglutaminase in rat brain carcinogenesis and in gliomas.

Tunici P, Sessa A, Rabellotti E, Calloni A, Perin A.

Cancer Lett. 1999 Jun 1;140(1-2):47-51.

PMID:
10403540
30.

Changes in hepatic polyamine catabolism in elderly rats.

Ferioli ME, Sessa A, Rabellotti E, Tunici P, Pinotti O, Perin A.

Liver. 1998 Oct;18(5):326-30.

PMID:
9831361
31.

Oxidative degradation of polyamines in rat pancreatic hypertrophy.

Rabellotti E, Sessa A, Tunici P, Bardocz S, Grant G, Pusztai A, Perin A.

Biochim Biophys Acta. 1998 Apr 28;1406(3):321-6.

32.

Transglutaminase activity in rat brain after ethanol exposure.

Sessa A, Tunici P, Rabellotti E, Perin A.

Alcohol Clin Exp Res. 1997 Oct;21(7):1241-5.

PMID:
9347085
33.

Response of intestinal transglutaminase activity to dietary phytohaemagglutinin.

Sessa A, Tunici P, Rabellotti E, Bardocz S, Grant G, Pusztai A, Perin A.

Biochim Biophys Acta. 1996 Nov 8;1314(1-2):66-70.

34.

Aging and polyamine acetylation in rat kidney.

Ferioli ME, Sessa A, Tunici P, Pinotti O, Perin A.

Biochim Biophys Acta. 1996 Oct 7;1317(1):15-8.

35.

Transglutaminase activity in rat liver after acute ethanol administration.

Sessa A, Tunici P, Perilli E, Perin A.

Biochim Biophys Acta. 1995 Dec 14;1245(3):371-5.

PMID:
8541314
36.

Polyamine acetylation in rat brain during N-ethyl-N-nitrosourea-induced cerebral carcinogenesis.

Sessa A, Tunici P, Perin A.

Cancer Lett. 1995 Oct 20;97(1):123-8.

PMID:
7585471
37.

Diamine and polyamine oxidase activities in phytohaemagglutinin-induced growth of rat small intestine.

Sessa A, Tunici P, Ewen SW, Grant G, Pusztai A, Bardocz S, Perin A.

Biochim Biophys Acta. 1995 May 11;1244(1):198-202.

PMID:
7766659

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