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Items: 15

1.

The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans.

Tirosh A, Calay ES, Tuncman G, Claiborn KC, Inouye KE, Eguchi K, Alcala M, Rathaus M, Hollander KS, Ron I, Livne R, Heianza Y, Qi L, Shai I, Garg R, Hotamisligil GS.

Sci Transl Med. 2019 Apr 24;11(489). pii: eaav0120. doi: 10.1126/scitranslmed.aav0120.

PMID:
31019023
2.

Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.

Burak MF, Inouye KE, White A, Lee A, Tuncman G, Calay ES, Sekiya M, Tirosh A, Eguchi K, Birrane G, Lightwood D, Howells L, Odede G, Hailu H, West S, Garlish R, Neale H, Doyle C, Moore A, Hotamisligil GS.

Sci Transl Med. 2015 Dec 23;7(319):319ra205. doi: 10.1126/scitranslmed.aac6336. Epub 2015 Dec 23.

PMID:
26702093
3.

Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

Cao H, Sekiya M, Ertunc ME, Burak MF, Mayers JR, White A, Inouye K, Rickey LM, Ercal BC, Furuhashi M, Tuncman G, Hotamisligil GS.

Cell Metab. 2013 May 7;17(5):768-78. doi: 10.1016/j.cmet.2013.04.012.

4.

Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis.

Nakamura T, Furuhashi M, Li P, Cao H, Tuncman G, Sonenberg N, Gorgun CZ, Hotamisligil GS.

Cell. 2010 Feb 5;140(3):338-48. doi: 10.1016/j.cell.2010.01.001.

5.

Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice.

Furuhashi M, Fucho R, Görgün CZ, Tuncman G, Cao H, Hotamisligil GS.

J Clin Invest. 2008 Jul;118(7):2640-50. doi: 10.1172/JCI34750.

6.

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.

Furuhashi M, Tuncman G, Görgün CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS.

Nature. 2007 Jun 21;447(7147):959-65. Epub 2007 Jun 6.

7.

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.

Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS.

Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10741-6. Epub 2006 Jul 3.

8.

A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease.

Tuncman G, Erbay E, Hom X, De Vivo I, Campos H, Rimm EB, Hotamisligil GS.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6970-5. Epub 2006 Apr 25.

9.

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.

Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS.

Science. 2004 Oct 15;306(5695):457-61.

10.

Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1.

Pandey M, Tuncman G, Hotamisligil GS, Samad F.

Am J Pathol. 2003 Mar;162(3):933-41.

11.

A central role for JNK in obesity and insulin resistance.

Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS.

Nature. 2002 Nov 21;420(6913):333-6.

PMID:
12447443
12.

An Extra Benefit of Allogeneic Peripheral Blood Stem Cell Transplantation in a Patient with Lymphoblastic Lymphoma: Cure of Thalassemia Minor.

Çelebi H, Üstün C, Arat M, Akan H, Tunçman G, Özçelik T, Coşkun HŞ, Koç H.

Turk J Haematol. 2000 Jun 5;16(4):77-9.

PMID:
27265858
13.

Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia.

Peller S, Yona R, Kopilova Y, Prokocimer M, Goldfinger N, Uysal A, Karabulut HG, Tukun A, Bokesoy I, Tuncman G, Rotter V.

Genes Chromosomes Cancer. 1998 Jan;21(1):2-7.

PMID:
9443036
14.

Null alleles of the aldolase B gene in patients with hereditary fructose intolerance.

Ali M, Tunçman G, Cross NC, Vidailhet M, Bökesoy I, Gitzelmann R, Cox TM.

J Med Genet. 1994 Jun;31(6):499-503.

15.

A case of Prader Willi syndrome with del 15 (q11-->q13).

Tunçman G, Tükün A, Yalaz K, Bökesoy I.

Turk J Pediatr. 1993 Oct-Dec;35(4):333-6.

PMID:
8160287

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