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Items: 1 to 50 of 225

1.

Both Immune Priming and Egg-adaptation in the Vaccine Influence Antibody Responses to Circulating A(H1N1)pdm09 Viruses Following Influenza Vaccination in Adults.

Liu F, Tzeng WP, Horner L, Kamal RP, Tatum HR, Blanchard EG, Xu X, York I, Tumpey TM, Katz JM, Lu X, Levine MZ.

J Infect Dis. 2018 Jun 21. doi: 10.1093/infdis/jiy376. [Epub ahead of print]

PMID:
29931203
2.

Multi-clade H5N1 virus-like particles: Immunogenicity and protection against H5N1 virus and effects of beta-propiolactone.

Pushko P, Tretyakova I, Hidajat R, Sun X, Belser JA, Tumpey TM.

Vaccine. 2018 Jul 5;36(29):4346-4353. doi: 10.1016/j.vaccine.2018.05.092. Epub 2018 Jun 7.

PMID:
29885769
3.

Pathogenesis and Transmission of Genetically Diverse Swine-Origin H3N2 Variant Influenza A Viruses from Multiple Lineages Isolated in the United States, 2011-2016.

Sun X, Pulit-Penaloza JA, Belser JA, Pappas C, Pearce MB, Brock N, Zeng H, Creager HM, Zanders N, Jang Y, Tumpey TM, Davis CT, Maines TR.

J Virol. 2018 Jul 31;92(16). pii: e00665-18. doi: 10.1128/JVI.00665-18. Print 2018 Aug 15.

PMID:
29848587
4.

Antigenically Diverse Swine Origin H1N1 Variant Influenza Viruses Exhibit Differential Ferret Pathogenesis and Transmission Phenotypes.

Pulit-Penaloza JA, Jones J, Sun X, Jang Y, Thor S, Belser JA, Zanders N, Creager HM, Ridenour C, Wang L, Stark TJ, Garten R, Chen LM, Barnes J, Tumpey TM, Wentworth DE, Maines TR, Davis CT.

J Virol. 2018 May 14;92(11). pii: e00095-18. doi: 10.1128/JVI.00095-18. Print 2018 Jun 1.

PMID:
29540597
5.

The eyes have it: influenza virus infection beyond the respiratory tract.

Belser JA, Lash RR, Garg S, Tumpey TM, Maines TR.

Lancet Infect Dis. 2018 Jul;18(7):e220-e227. doi: 10.1016/S1473-3099(18)30102-6. Epub 2018 Feb 21. Review.

6.

The 1918 flu, 100 years later.

Belser JA, Tumpey TM.

Science. 2018 Jan 19;359(6373):255. doi: 10.1126/science.aas9565. No abstract available.

PMID:
29348212
7.

Infection and Replication of Influenza Virus at the Ocular Surface.

Creager HM, Kumar A, Zeng H, Maines TR, Tumpey TM, Belser JA.

J Virol. 2018 Mar 14;92(7). pii: e02192-17. doi: 10.1128/JVI.02192-17. Print 2018 Apr 1.

PMID:
29321303
8.

An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial.

DeZure AD, Coates EE, Hu Z, Yamshchikov GV, Zephir KL, Enama ME, Plummer SH, Gordon IJ, Kaltovich F, Andrews S, McDermott A, Crank MC, Koup RA, Schwartz RM, Bailer RT, Sun X, Mascola JR, Tumpey TM, Graham BS, Ledgerwood JE.

NPJ Vaccines. 2017 Jun 1;2:15. doi: 10.1038/s41541-017-0016-6. eCollection 2017.

9.

Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017.

Belser JA, Brock N, Sun X, Jones J, Zanders N, Hodges E, Pulit-Penaloza JA, Wentworth D, Tumpey TM, Davis T, Maines TR.

Emerg Infect Dis. 2018 Jan;24(1):149-152. doi: 10.3201/eid2401.171574.

10.

Airborne Transmission of Highly Pathogenic Influenza Virus during Processing of Infected Poultry.

Bertran K, Balzli C, Kwon YK, Tumpey TM, Clark A, Swayne DE.

Emerg Infect Dis. 2017 Nov;23(11):1806-1814. doi: 10.3201/eid2311.170672.

11.

Effect of Priming With Seasonal Influenza A(H3N2) Virus on the Prevalence of Cross-Reactive Hemagglutination-Inhibition Antibodies to Swine-Origin A(H3N2) Variants.

Liu F, Veguilla V, Gross FL, Gillis E, Rowe T, Xu X, Tumpey TM, Katz JM, Levine MZ, Lu X.

J Infect Dis. 2017 Sep 15;216(suppl_4):S539-S547. doi: 10.1093/infdis/jix093.

PMID:
28934461
12.

Assessment of Molecular, Antigenic, and Pathological Features of Canine Influenza A(H3N2) Viruses That Emerged in the United States.

Pulit-Penaloza JA, Simpson N, Yang H, Creager HM, Jones J, Carney P, Belser JA, Yang G, Chang J, Zeng H, Thor S, Jang Y, Killian ML, Jenkins-Moore M, Janas-Martindale A, Dubovi E, Wentworth DE, Stevens J, Tumpey TM, Davis CT, Maines TR.

J Infect Dis. 2017 Sep 15;216(suppl_4):S499-S507. doi: 10.1093/infdis/jiw620.

13.

Pathogenesis, Transmissibility, and Tropism of a Highly Pathogenic Avian Influenza A(H7N7) Virus Associated With Human Conjunctivitis in Italy, 2013.

Belser JA, Creager HM, Zeng H, Maines TR, Tumpey TM.

J Infect Dis. 2017 Sep 15;216(suppl_4):S508-S511. doi: 10.1093/infdis/jiw559.

14.

An influenza A virus (H7N9) anti-neuraminidase monoclonal antibody protects mice from morbidity without interfering with the development of protective immunity to subsequent homologous challenge.

Wilson JR, Belser JA, DaSilva J, Guo Z, Sun X, Gansebom S, Bai Y, Stark TJ, Chang J, Carney P, Levine MZ, Barnes J, Stevens J, Maines TR, Tumpey TM, York IA.

Virology. 2017 Nov;511:214-221. doi: 10.1016/j.virol.2017.08.016. Epub 2017 Sep 6.

15.

Pathogenicity testing of influenza candidate vaccine viruses in the ferret model.

Belser JA, Johnson A, Pulit-Penaloza JA, Pappas C, Pearce MB, Tzeng WP, Hossain MJ, Ridenour C, Wang L, Chen LM, Wentworth DE, Katz JM, Maines TR, Tumpey TM.

Virology. 2017 Nov;511:135-141. doi: 10.1016/j.virol.2017.08.024. Epub 2017 Aug 29.

16.

Neuraminidase-based recombinant virus-like particles protect against lethal avian influenza A(H5N1) virus infection in ferrets.

Smith GE, Sun X, Bai Y, Liu YV, Massare MJ, Pearce MB, Belser JA, Maines TR, Creager HM, Glenn GM, Flyer D, Pushko P, Levine MZ, Tumpey TM.

Virology. 2017 Sep;509:90-97. doi: 10.1016/j.virol.2017.06.006. Epub 2017 Jun 16.

17.

Stockpiled pre-pandemic H5N1 influenza virus vaccines with AS03 adjuvant provide cross-protection from H5N2 clade 2.3.4.4 virus challenge in ferrets.

Sun X, Belser JA, Pulit-Penaloza JA, Creager HM, Guo Z, Jefferson SN, Liu F, York IA, Stevens J, Maines TR, Jernigan DB, Katz JM, Levine MZ, Tumpey TM.

Virology. 2017 Aug;508:164-169. doi: 10.1016/j.virol.2017.05.010. Epub 2017 May 26.

18.

A Novel A(H7N2) Influenza Virus Isolated from a Veterinarian Caring for Cats in a New York City Animal Shelter Causes Mild Disease and Transmits Poorly in the Ferret Model.

Belser JA, Pulit-Penaloza JA, Sun X, Brock N, Pappas C, Creager HM, Zeng H, Tumpey TM, Maines TR.

J Virol. 2017 Jul 12;91(15). pii: e00672-17. doi: 10.1128/JVI.00672-17. Print 2017 Aug 1.

19.

Enhanced virulence of clade 2.3.2.1 highly pathogenic avian influenza A H5N1 viruses in ferrets.

Pearce MB, Pappas C, Gustin KM, Davis CT, Pantin-Jackwood MJ, Swayne DE, Maines TR, Belser JA, Tumpey TM.

Virology. 2017 Feb;502:114-122. doi: 10.1016/j.virol.2016.12.024. Epub 2016 Dec 27.

20.

Role of H7 hemagglutinin in murine infectivity of influenza viruses following ocular inoculation.

Belser JA, Sun X, Creager HM, Johnson A, Ridenour C, Chen LM, Tumpey TM, Maines TR.

Virology. 2017 Feb;502:13-19. doi: 10.1016/j.virol.2016.12.008. Epub 2016 Dec 10.

21.

Virus-like particles displaying H5, H7, H9 hemagglutinins and N1 neuraminidase elicit protective immunity to heterologous avian influenza viruses in chickens.

Pushko P, Tretyakova I, Hidajat R, Zsak A, Chrzastek K, Tumpey TM, Kapczynski DR.

Virology. 2017 Jan 15;501:176-182. doi: 10.1016/j.virol.2016.12.001. Epub 2016 Dec 6.

22.

Constitutively Expressed IFITM3 Protein in Human Endothelial Cells Poses an Early Infection Block to Human Influenza Viruses.

Sun X, Zeng H, Kumar A, Belser JA, Maines TR, Tumpey TM.

J Virol. 2016 Nov 28;90(24):11157-11167. Print 2016 Dec 15.

23.

In vitro exposure system for study of aerosolized influenza virus.

Creager HM, Zeng H, Pulit-Penaloza JA, Maines TR, Tumpey TM, Belser JA.

Virology. 2017 Jan;500:62-70. doi: 10.1016/j.virol.2016.10.007. Epub 2016 Oct 20.

24.

Pathogenesis and Transmission Assessments of Two H7N8 Influenza A Viruses Recently Isolated from Turkey Farms in Indiana Using Mouse and Ferret Models.

Sun X, Belser JA, Pulit-Penaloza JA, Zeng H, Lewis A, Shieh WJ, Tumpey TM, Maines TR.

J Virol. 2016 Nov 14;90(23):10936-10944. Print 2016 Dec 1.

25.

Mono- and quadri-subtype virus-like particles (VLPs) containing H10 subtype elicit protective immunity to H10 influenza in a ferret challenge model.

Pushko P, Sun X, Tretyakova I, Hidajat R, Pulit-Penaloza JA, Belser JA, Maines TR, Tumpey TM.

Vaccine. 2016 Oct 17;34(44):5235-5242. doi: 10.1016/j.vaccine.2016.09.012. Epub 2016 Sep 20.

26.

Complexities in Ferret Influenza Virus Pathogenesis and Transmission Models.

Belser JA, Eckert AM, Tumpey TM, Maines TR.

Microbiol Mol Biol Rev. 2016 Jul 13;80(3):733-44. doi: 10.1128/MMBR.00022-16. Print 2016 Sep. Review.

27.

A cationic liposome-DNA complexes adjuvant (JVRS-100) enhances the immunogenicity and cross-protective efficacy of pre-pandemic influenza A (H5N1) vaccine in ferrets.

Liu F, Sun X, Fairman J, Lewis DB, Katz JM, Levine M, Tumpey TM, Lu X.

Virology. 2016 May;492:197-203. doi: 10.1016/j.virol.2016.02.024. Epub 2016 Mar 21.

28.

Mammalian Pathogenesis and Transmission of H7N9 Influenza Viruses from Three Waves, 2013-2015.

Belser JA, Creager HM, Sun X, Gustin KM, Jones T, Shieh WJ, Maines TR, Tumpey TM.

J Virol. 2016 Apr 14;90(9):4647-4657. doi: 10.1128/JVI.00134-16. Print 2016 May.

29.

Vaccination with virus-like particles containing H5 antigens from three H5N1 clades protects chickens from H5N1 and H5N8 influenza viruses.

Kapczynski DR, Tumpey TM, Hidajat R, Zsak A, Chrzastek K, Tretyakova I, Pushko P.

Vaccine. 2016 Mar 18;34(13):1575-1581. doi: 10.1016/j.vaccine.2016.02.011. Epub 2016 Feb 8.

30.
31.

Preparation of quadri-subtype influenza virus-like particles using bovine immunodeficiency virus gag protein.

Tretyakova I, Hidajat R, Hamilton G, Horn N, Nickols B, Prather RO, Tumpey TM, Pushko P.

Virology. 2016 Jan;487:163-71. doi: 10.1016/j.virol.2015.10.007. Epub 2015 Nov 2.

32.

Detection and Characterization of Clade 1 Reassortant H5N1 Viruses Isolated from Human Cases in Vietnam during 2013.

Thor SW, Nguyen H, Balish A, Hoang AN, Gustin KM, Nhung PT, Jones J, Thu NN, Davis W, Ngoc TN, Jang Y, Sleeman K, Villanueva J, Kile J, Gubareva LV, Lindstrom S, Tumpey TM, Davis CT, Long NT.

PLoS One. 2015 Aug 5;10(8):e0133867. doi: 10.1371/journal.pone.0133867. eCollection 2015.

33.

Pathogenesis and Transmission of Novel Highly Pathogenic Avian Influenza H5N2 and H5N8 Viruses in Ferrets and Mice.

Pulit-Penaloza JA, Sun X, Creager HM, Zeng H, Belser JA, Maines TR, Tumpey TM.

J Virol. 2015 Oct;89(20):10286-93. doi: 10.1128/JVI.01438-15. Epub 2015 Jul 29.

34.

Recombinant H7 hemagglutinin forms subviral particles that protect mice and ferrets from challenge with H7N9 influenza virus.

Pushko P, Pujanauski LM, Sun X, Pearce M, Hidajat R, Kort T, Schwartzman LM, Tretyakova I, Chunqing L, Taubenberger JK, Tumpey TM.

Vaccine. 2015 Sep 11;33(38):4975-82. doi: 10.1016/j.vaccine.2015.07.026. Epub 2015 Jul 21.

35.

Oseltamivir inhibits influenza virus replication and transmission following ocular-only aerosol inoculation of ferrets.

Belser JA, Maines TR, Creager HM, Katz JM, Tumpey TM.

Virology. 2015 Oct;484:305-12. doi: 10.1016/j.virol.2015.06.020. Epub 2015 Jul 3.

36.

Environmental Conditions Affect Exhalation of H3N2 Seasonal and Variant Influenza Viruses and Respiratory Droplet Transmission in Ferrets.

Gustin KM, Belser JA, Veguilla V, Zeng H, Katz JM, Tumpey TM, Maines TR.

PLoS One. 2015 May 13;10(5):e0125874. doi: 10.1371/journal.pone.0125874. eCollection 2015.

37.

Phase 1 study of pandemic H1 DNA vaccine in healthy adults.

Crank MC, Gordon IJ, Yamshchikov GV, Sitar S, Hu Z, Enama ME, Holman LA, Bailer RT, Pearce MB, Koup RA, Mascola JR, Nabel GJ, Tumpey TM, Schwartz RM, Graham BS, Ledgerwood JE; VRC 308 Study Team.

PLoS One. 2015 Apr 17;10(4):e0123969. doi: 10.1371/journal.pone.0123969. eCollection 2015.

38.

Recombinant virus-like particles elicit protective immunity against avian influenza A(H7N9) virus infection in ferrets.

Liu YV, Massare MJ, Pearce MB, Sun X, Belser JA, Maines TR, Creager HM, Glenn GM, Pushko P, Smith GE, Tumpey TM.

Vaccine. 2015 Apr 27;33(18):2152-8. doi: 10.1016/j.vaccine.2015.03.009. Epub 2015 Mar 13.

39.

Comparison of traditional intranasal and aerosol inhalation inoculation of mice with influenza A viruses.

Belser JA, Gustin KM, Katz JM, Maines TR, Tumpey TM.

Virology. 2015 Jul;481:107-12. doi: 10.1016/j.virol.2015.02.041. Epub 2015 Mar 13.

40.

A(H7N9) virus results in early induction of proinflammatory cytokine responses in both human lung epithelial and endothelial cells and shows increased human adaptation compared with avian H5N1 virus.

Zeng H, Belser JA, Goldsmith CS, Gustin KM, Veguilla V, Katz JM, Tumpey TM.

J Virol. 2015 Apr;89(8):4655-67. doi: 10.1128/JVI.03095-14. Epub 2015 Feb 11.

41.

Assessment of transmission, pathogenesis and adaptation of H2 subtype influenza viruses in ferrets.

Pappas C, Yang H, Carney PJ, Pearce MB, Katz JM, Stevens J, Tumpey TM.

Virology. 2015 Mar;477:61-71. doi: 10.1016/j.virol.2015.01.002. Epub 2015 Feb 5.

42.

Use of highly pathogenic avian influenza A(H5N1) gain-of-function studies for molecular-based surveillance and pandemic preparedness.

Davis CT, Chen LM, Pappas C, Stevens J, Tumpey TM, Gubareva LV, Katz JM, Villanueva JM, Donis RO, Cox NJ.

MBio. 2014 Dec 12;5(6). pii: e02431-14. doi: 10.1128/mBio.02431-14. No abstract available.

43.

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease.

Peng X, Alföldi J, Gori K, Eisfeld AJ, Tyler SR, Tisoncik-Go J, Brawand D, Law GL, Skunca N, Hatta M, Gasper DJ, Kelly SM, Chang J, Thomas MJ, Johnson J, Berlin AM, Lara M, Russell P, Swofford R, Turner-Maier J, Young S, Hourlier T, Aken B, Searle S, Sun X, Yi Y, Suresh M, Tumpey TM, Siepel A, Wisely SM, Dessimoz C, Kawaoka Y, Birren BW, Lindblad-Toh K, Di Palma F, Engelhardt JF, Palermo RE, Katze MG.

Nat Biotechnol. 2014 Dec;32(12):1250-5. doi: 10.1038/nbt.3079. Epub 2014 Nov 17.

44.

Effect of receptor binding specificity on the immunogenicity and protective efficacy of influenza virus A H1 vaccines.

Sun X, Cao W, Pappas C, Liu F, Katz JM, Tumpey TM.

Virology. 2014 Sep;464-465:156-165. doi: 10.1016/j.virol.2014.07.004. Epub 2014 Jul 30.

45.

Mammalian models for the study of H7 virus pathogenesis and transmission.

Belser JA, Tumpey TM.

Curr Top Microbiol Immunol. 2014;385:275-305. doi: 10.1007/82_2014_383. Review.

46.

H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice.

Morrison J, Josset L, Tchitchek N, Chang J, Belser JA, Swayne DE, Pantin-Jackwood MJ, Tumpey TM, Katze MG.

J Virol. 2014 Sep;88(18):10556-68. doi: 10.1128/JVI.00570-14. Epub 2014 Jul 2.

47.

Influenza virus infectivity and virulence following ocular-only aerosol inoculation of ferrets.

Belser JA, Gustin KM, Katz JM, Maines TR, Tumpey TM.

J Virol. 2014 Sep 1;88(17):9647-54. doi: 10.1128/JVI.01067-14. Epub 2014 Jun 11.

48.

Evaluation of the antigenic relatedness and cross-protective immunity of the neuraminidase between human influenza A (H1N1) virus and highly pathogenic avian influenza A (H5N1) virus.

Lu X, Liu F, Zeng H, Sheu T, Achenbach JE, Veguilla V, Gubareva LV, Garten R, Smith C, Yang H, Stevens J, Xu X, Katz JM, Tumpey TM.

Virology. 2014 Apr;454-455:169-75. doi: 10.1016/j.virol.2014.02.011. Epub 2014 Mar 5.

50.

Tropism of H7N9 influenza viruses in the human respiratory tract.

Belser JA, Tumpey TM.

Lancet Respir Med. 2013 Sep;1(7):501-2. doi: 10.1016/S2213-2600(13)70161-9. Epub 2013 Jul 25. No abstract available.

PMID:
24461601

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