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Items: 1 to 50 of 285

1.

Dynamic action of the Sec machinery during initiation, protein translocation and termination.

Fessl T, Watkins D, Oatley P, Allen WJ, Corey RA, Horne J, Baldwin SA, Radford SE, Collinson I, Tuma R.

Elife. 2018 Jun 7;7. pii: e35112. doi: 10.7554/eLife.35112.

2.

Cocaine-mediated activation of microglia and microglial MeCP2 and BDNF production.

Cotto B, Li H, Tuma RF, Ward SJ, Langford D.

Neurobiol Dis. 2018 Sep;117:28-41. doi: 10.1016/j.nbd.2018.05.017. Epub 2018 May 30.

PMID:
29859319
3.

Stability of local secondary structure determines selectivity of viral RNA chaperones.

Bravo JPK, Borodavka A, Barth A, Calabrese AN, Mojzes P, Cockburn JJB, Lamb DC, Tuma R.

Nucleic Acids Res. 2018 May 18. doi: 10.1093/nar/gky394. [Epub ahead of print]

PMID:
29796667
4.

The non-psychoactive phytocannabinoid cannabidiol (CBD) attenuates pro-inflammatory mediators, T cell infiltration, and thermal sensitivity following spinal cord injury in mice.

Li H, Kong W, Chambers CR, Yu D, Ganea D, Tuma RF, Ward SJ.

Cell Immunol. 2018 Jul;329:1-9. doi: 10.1016/j.cellimm.2018.02.016. Epub 2018 Mar 8.

PMID:
29784129
5.

Artificial Differences in Clostridium difficile Infection Rates Associated with Disparity in Testing.

Kamboj M, Brite J, Aslam A, Kennington J, Babady NE, Calfee D, Furuya Y, Chen D, Augenbraun M, Ostrowsky B, Patel G, Mircescu M, Kak V, Tuma R, Karre TA, Fry DA, Duhaney YP, Moyer A, Mitchell D, Cantu S, Hsieh C, Warren N, Martin S, Willson J, Dickman J, Knight J, Delahanty K, Flood A, Harrington J, Korenstein D, Eagan J, Sepkowitz K.

Emerg Infect Dis. 2018 Mar;24(3):584-587. doi: 10.3201/eid2403.170961.

6.

Single and combined effects of plant-derived and synthetic cannabinoids on cognition and cannabinoid-associated withdrawal signs in mice.

Myers AM, Siegele PB, Foss JD, Tuma RF, Ward SJ.

Br J Pharmacol. 2018 Jan 16. doi: 10.1111/bph.14147. [Epub ahead of print]

PMID:
29338068
7.

Surprising outcomes in cannabinoid CB1/CB2 receptor double knockout mice in two models of ischemia.

Ward SJ, Castelli F, Reichenbach ZW, Tuma RF.

Life Sci. 2018 Feb 15;195:1-5. doi: 10.1016/j.lfs.2017.12.030. Epub 2017 Dec 27.

PMID:
29288767
8.

Rewriting nature's assembly manual for a ssRNA virus.

Patel N, Wroblewski E, Leonov G, Phillips SEV, Tuma R, Twarock R, Stockley PG.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12255-12260. doi: 10.1073/pnas.1706951114. Epub 2017 Oct 30.

9.

Age related changes in laying pattern and egg weight of different laying hen genotypes.

Tůmová E, Uhlířová L, Tůma R, Chodová D, Máchal L.

Anim Reprod Sci. 2017 Aug;183:21-26. doi: 10.1016/j.anireprosci.2017.06.006. Epub 2017 Jun 23.

PMID:
28683955
10.

Effects of membrane curvature and pH on proton pumping activity of single cytochrome bo3 enzymes.

Li M, Khan S, Rong H, Tuma R, Hatzakis NS, Jeuken LJC.

Biochim Biophys Acta. 2017 Sep;1858(9):763-770. doi: 10.1016/j.bbabio.2017.06.003. Epub 2017 Jun 17.

11.

HBV RNA pre-genome encodes specific motifs that mediate interactions with the viral core protein that promote nucleocapsid assembly.

Patel N, White SJ, Thompson RF, Bingham R, Weiß EU, Maskell DP, Zlotnick A, Dykeman E, Tuma R, Twarock R, Ranson NA, Stockley PG.

Nat Microbiol. 2017 Jun 19;2:17098. doi: 10.1038/nmicrobiol.2017.98.

12.

Single and combined effects of Δ9 -tetrahydrocannabinol and cannabidiol in a mouse model of chemotherapy-induced neuropathic pain.

King KM, Myers AM, Soroka-Monzo AJ, Tuma RF, Tallarida RJ, Walker EA, Ward SJ.

Br J Pharmacol. 2017 Sep;174(17):2832-2841. doi: 10.1111/bph.13887. Epub 2017 Jul 27.

PMID:
28548225
13.

Inducing protein aggregation by extensional flow.

Dobson J, Kumar A, Willis LF, Tuma R, Higazi DR, Turner R, Lowe DC, Ashcroft AE, Radford SE, Kapur N, Brockwell DJ.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4673-4678. doi: 10.1073/pnas.1702724114. Epub 2017 Apr 17.

14.

Rare complication of ventriculoperitoneal shunt: Catheter protrusion to subcutaneous tissue - Case report.

Gatto LA, Mathias R, Tuma R, Abdalla R, de Aguiar PH.

Surg Neurol Int. 2016 Dec 28;7(Suppl 44):S1142-S1146. doi: 10.4103/2152-7806.196926. eCollection 2016.

15.

Sizes of Long RNA Molecules Are Determined by the Branching Patterns of Their Secondary Structures.

Borodavka A, Singaram SW, Stockley PG, Gelbart WM, Ben-Shaul A, Tuma R.

Biophys J. 2016 Nov 15;111(10):2077-2085. doi: 10.1016/j.bpj.2016.10.014.

16.

Nurse-led hepatocellular carcinoma surveillance clinic provides an effective method of monitoring patients with cirrhosis.

Nazareth S, Leembruggen N, Tuma R, Chen SL, Rao S, Kontorinis N, Cheng W.

Int J Nurs Pract. 2016 Jun;22 Suppl 2:3-11. doi: 10.1111/ijn.12472. Erratum in: Int J Nurs Pract. 2016 Oct;22(5):526.

PMID:
27476494
17.

The CB1 antagonist, SR141716A, is protective in permanent photothrombotic cerebral ischemia.

Reichenbach ZW, Li H, Ward SJ, Tuma RF.

Neurosci Lett. 2016 Sep 6;630:9-15. doi: 10.1016/j.neulet.2016.07.041. Epub 2016 Jul 21.

18.

Biophysical Characterization of Chromatin Remodeling Protein CHD4.

Morra R, Fessl T, Wang Y, Mancini EJ, Tuma R.

Methods Mol Biol. 2016;1431:175-93. doi: 10.1007/978-1-4939-3631-1_14.

PMID:
27283310
19.

Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation.

Allen WJ, Corey RA, Oatley P, Sessions RB, Baldwin SA, Radford SE, Tuma R, Collinson I.

Elife. 2016 May 16;5. pii: e15598. doi: 10.7554/eLife.15598.

20.

Bacteriophage MS2 genomic RNA encodes an assembly instruction manual for its capsid.

Stockley PG, White SJ, Dykeman E, Manfield I, Rolfsson O, Patel N, Bingham R, Barker A, Wroblewski E, Chandler-Bostock R, Weiß EU, Ranson NA, Tuma R, Twarock R.

Bacteriophage. 2016 Mar 2;6(1):e1157666. eCollection 2016 Jan-Mar.

21.

Single Enzyme Experiments Reveal a Long-Lifetime Proton Leak State in a Heme-Copper Oxidase.

Li M, Jørgensen SK, McMillan DG, Krzemiński Ł, Daskalakis NN, Partanen RH, Tutkus M, Tuma R, Stamou D, Hatzakis NS, Jeuken LJ.

J Am Chem Soc. 2015 Dec 30;137(51):16055-63. doi: 10.1021/jacs.5b08798. Epub 2015 Dec 17.

22.

Mutations in RNA Polymerase Bridge Helix and Switch Regions Affect Active-Site Networks and Transcript-Assisted Hydrolysis.

Zhang N, Schäfer J, Sharma A, Rayner L, Zhang X, Tuma R, Stockley P, Buck M.

J Mol Biol. 2015 Nov 6;427(22):3516-3526. doi: 10.1016/j.jmb.2015.09.005. Epub 2015 Sep 10.

23.

IV and IP administration of rhodamine in visualization of WBC-BBB interactions in cerebral vessels.

Reichenbach ZW, Li H, Gaughan JP, Elliott M, Tuma R.

Microsc Res Tech. 2015 Oct;78(10):894-9. doi: 10.1002/jemt.22552. Epub 2015 Jul 24.

24.

Evidence that avian reovirus σNS is an RNA chaperone: implications for genome segment assortment.

Borodavka A, Ault J, Stockley PG, Tuma R.

Nucleic Acids Res. 2015 Aug 18;43(14):7044-57. doi: 10.1093/nar/gkv639. Epub 2015 Jun 24.

25.

A selective cannabinoid CB2 agonist attenuates damage and improves memory retention following stroke in mice.

Ronca RD, Myers AM, Ganea D, Tuma RF, Walker EA, Ward SJ.

Life Sci. 2015 Oct 1;138:72-7. doi: 10.1016/j.lfs.2015.05.005. Epub 2015 May 30.

26.

pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers.

Tipping KW, Karamanos TK, Jakhria T, Iadanza MG, Goodchild SC, Tuma R, Ranson NA, Hewitt EW, Radford SE.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5691-6. doi: 10.1073/pnas.1423174112. Epub 2015 Apr 20.

27.

Revealing the density of encoded functions in a viral RNA.

Patel N, Dykeman EC, Coutts RH, Lomonossoff GP, Rowlands DJ, Phillips SE, Ranson N, Twarock R, Tuma R, Stockley PG.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2227-32. doi: 10.1073/pnas.1420812112. Epub 2015 Feb 2.

28.

Distinct interactions of cannabidiol and morphine in three nociceptive behavioral models in mice.

Neelakantan H, Tallarida RJ, Reichenbach ZW, Tuma RF, Ward SJ, Walker EA.

Behav Pharmacol. 2015 Apr;26(3):304-14. doi: 10.1097/FBP.0000000000000119.

PMID:
25485642
29.

Cannabinoid receptor type-2 stimulation, blockade, and deletion alter the vascular inflammatory responses to traumatic brain injury.

Amenta PS, Jallo JI, Tuma RF, Hooper DC, Elliott MB.

J Neuroinflammation. 2014 Nov 22;11:191. doi: 10.1186/s12974-014-0191-6.

30.

Functional dynamics of hexameric helicase probed by hydrogen exchange and simulation.

Radou G, Dreyer FN, Tuma R, Paci E.

Biophys J. 2014 Aug 19;107(4):983-90. doi: 10.1016/j.bpj.2014.06.039.

31.

Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site: insights from single molecule studies.

Sharma A, Leach RN, Gell C, Zhang N, Burrows PC, Shepherd DA, Wigneshweraraj S, Smith DA, Zhang X, Buck M, Stockley PG, Tuma R.

Nucleic Acids Res. 2014 Apr;42(8):5177-90. doi: 10.1093/nar/gku146. Epub 2014 Feb 19.

32.

TALE proteins bind to both active and inactive chromatin.

Scott JN, Kupinski AP, Kirkham CM, Tuma R, Boyes J.

Biochem J. 2014 Feb 15;458(1):153-8. doi: 10.1042/BJ20131327.

33.

Selective CB2 receptor activation ameliorates EAE by reducing Th17 differentiation and immune cell accumulation in the CNS.

Kong W, Li H, Tuma RF, Ganea D.

Cell Immunol. 2014 Jan;287(1):1-17. doi: 10.1016/j.cellimm.2013.11.002. Epub 2013 Nov 14.

34.

Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution.

El Omari K, Meier C, Kainov D, Sutton G, Grimes JM, Poranen MM, Bamford DH, Tuma R, Stuart DI, Mancini EJ.

Nucleic Acids Res. 2013 Nov;41(20):9396-410. doi: 10.1093/nar/gkt713. Epub 2013 Aug 11.

35.

Packaging signals in single-stranded RNA viruses: nature's alternative to a purely electrostatic assembly mechanism.

Stockley PG, Twarock R, Bakker SE, Barker AM, Borodavka A, Dykeman E, Ford RJ, Pearson AR, Phillips SE, Ranson NA, Tuma R.

J Biol Phys. 2013 Mar;39(2):277-87. doi: 10.1007/s10867-013-9313-0. Epub 2013 Apr 12.

36.

A two-stage mechanism of viral RNA compaction revealed by single molecule fluorescence.

Borodavka A, Tuma R, Stockley PG.

RNA Biol. 2013 Apr;10(4):481-9. doi: 10.4161/rna.23838. Epub 2013 Feb 19.

37.

Structural and functional roles of carotenoids in chlorosomes.

Pšencík J, Arellano JB, Collins AM, Laurinmäki P, Torkkeli M, Löflund B, Serimaa RE, Blankenship RE, Tuma R, Butcher SJ.

J Bacteriol. 2013 Apr;195(8):1727-34. doi: 10.1128/JB.02052-12. Epub 2013 Feb 8.

38.

P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor.

Navaneetham D, Wu W, Li H, Sinha D, Tuma RF, Walsh PN.

J Biochem. 2013 Feb;153(2):221-31. doi: 10.1093/jb/mvs133. Epub 2012 Nov 20.

39.

Evidence that viral RNAs have evolved for efficient, two-stage packaging.

Borodavka A, Tuma R, Stockley PG.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15769-74. Epub 2012 Sep 10.

40.

Signaling through cannabinoid receptor 2 suppresses murine dendritic cell migration by inhibiting matrix metalloproteinase 9 expression.

Adhikary S, Kocieda VP, Yen JH, Tuma RF, Ganea D.

Blood. 2012 Nov 1;120(18):3741-9. doi: 10.1182/blood-2012-06-435362. Epub 2012 Sep 12.

41.

Unique effects of compounds active at both cannabinoid and serotonin receptors during stroke.

Zhang M, Mahadevan A, Amere M, Li H, Ganea D, Tuma RF.

Transl Stroke Res. 2012 Sep;3(3):348-56. doi: 10.1007/s12975-012-0197-2. Epub 2012 Jul 26.

PMID:
24323810
42.

A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury.

Amenta PS, Jallo JI, Tuma RF, Elliott MB.

J Neurosci Res. 2012 Dec;90(12):2293-305. doi: 10.1002/jnr.23114. Epub 2012 Aug 18.

PMID:
22903455
43.

Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4.

Morra R, Lee BM, Shaw H, Tuma R, Mancini EJ.

FEBS Lett. 2012 Jul 30;586(16):2513-21. doi: 10.1016/j.febslet.2012.06.017. Epub 2012 Jun 27.

44.

Cancer stem cell hypothesis and trastuzumab in HER2-negative tumors.

Tuma RS.

J Natl Cancer Inst. 2012 Jul 3;104(13):968-9. doi: 10.1093/jnci/djs307. Epub 2012 Jun 28. No abstract available.

PMID:
22745473
45.

The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis.

Wu W, Li H, Navaneetham D, Reichenbach ZW, Tuma RF, Walsh PN.

Blood. 2012 Jul 19;120(3):671-7. doi: 10.1182/blood-2012-03-419523. Epub 2012 Jun 6.

46.

Prepping omics for the clinic.

Tuma RS.

J Natl Cancer Inst. 2012 May 16;104(10):727-8. doi: 10.1093/jnci/djs248. Epub 2012 Apr 27. No abstract available.

PMID:
22544945
47.

Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions.

Ramirez SH, Haskó J, Skuba A, Fan S, Dykstra H, McCormick R, Reichenbach N, Krizbai I, Mahadevan A, Zhang M, Tuma R, Son YJ, Persidsky Y.

J Neurosci. 2012 Mar 21;32(12):4004-16. doi: 10.1523/JNEUROSCI.4628-11.2012.

48.

Functional screens take on the cancer genome.

Tuma RS.

J Natl Cancer Inst. 2012 Feb 22;104(4):269-70. doi: 10.1093/jnci/djs132. Epub 2012 Feb 9. No abstract available.

PMID:
22327381
49.

Mechanism of RNA packaging motor.

Mancini EJ, Tuma R.

Adv Exp Med Biol. 2012;726:609-29. doi: 10.1007/978-1-4614-0980-9_27. Review.

PMID:
22297533
50.

ALK gene amplified in most inflammatory breast cancers.

Tuma RS.

J Natl Cancer Inst. 2012 Jan 18;104(2):87-8. doi: 10.1093/jnci/djr553. Epub 2012 Jan 3. No abstract available.

PMID:
22215853

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