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Items: 1 to 50 of 81

1.

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment.

Siraj AK, Pratheeshkumar P, Parvathareddy SK, Divya SP, Al-Dayel F, Tulbah A, Ajarim D, Al-Kuraya KS.

Oncotarget. 2018 Dec 18;9(99):37319-37332. doi: 10.18632/oncotarget.26470. eCollection 2018 Dec 18.

2.

Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects.

Al-Khalaf HH, Al-Harbi B, Al-Sayed A, Arafah M, Tulbah A, Jarman A, Al-Mohanna F, Aboussekhra A.

Mol Cell Biol. 2019 Jan 3;39(2). pii: e00332-18. doi: 10.1128/MCB.00332-18. Print 2019 Jan 15.

PMID:
30397072
3.

FoxM1 is an independent poor prognostic marker and therapeutic target for advanced Middle Eastern breast cancer.

Siraj AK, Pratheeshkumar P, Parvathareddy SK, Qadri Z, Thangavel S, Ahmed S, Al-Dayel F, Tulbah A, Ajarim D, Al-Kuraya KS.

Oncotarget. 2018 Apr 3;9(25):17466-17482. doi: 10.18632/oncotarget.24739. eCollection 2018 Apr 3.

4.

FoxM1 and β-catenin predicts aggressiveness in Middle Eastern ovarian cancer and their co-targeting impairs the growth of ovarian cancer cells.

Pratheeshkumar P, Divya SP, Parvathareddy SK, Alhoshani NM, Al-Badawi IA, Tulbah A, Al-Dayel F, Siraj AK, Al-Kuraya KS.

Oncotarget. 2017 Dec 16;9(3):3590-3604. doi: 10.18632/oncotarget.23338. eCollection 2018 Jan 9.

5.

The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts.

Al-Kharashi LA, Al-Mohanna FH, Tulbah A, Aboussekhra A.

Oncotarget. 2017 Dec 18;9(2):2329-2343. doi: 10.18632/oncotarget.23411. eCollection 2018 Jan 5.

6.

Expanding the spectrum of germline variants in cancer.

Siraj AK, Masoodi T, Bu R, Parvathareddy SK, Al-Badawi IA, Al-Sanea N, Ashari LH, Abduljabbar A, Alhomoud S, Al-Sobhi SS, Tulbah A, Ajarim D, Alzoman K, Aljuboury M, Yousef HB, Al-Dawish M, Al-Dayel F, Alkuraya FS, Al-Kuraya KS.

Hum Genet. 2017 Nov;136(11-12):1431-1444. doi: 10.1007/s00439-017-1845-0. Epub 2017 Oct 3.

PMID:
28975465
7.

Inhaled simvastatin nanoparticles for inflammatory lung disease.

Tulbah AS, Pisano E, Scalia S, Young PM, Traini D, Ong HX.

Nanomedicine (Lond). 2017 Oct;12(20):2471-2485. doi: 10.2217/nnm-2017-0188. Epub 2017 Sep 20.

PMID:
28972463
8.

Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity.

Al-Khalaf HH, Amir M, Al-Mohanna F, Tulbah A, Al-Sayed A, Aboussekhra A.

Mol Cell Biol. 2017 Aug 11;37(17). pii: e00101-17. doi: 10.1128/MCB.00101-17. Print 2017 Sep 1.

9.

Reply to "letter to the editor concerning the article-Impact of surgery on survival in stage IV breast cancer".

Al Johani B, Al Malik O, Anwar E, Tulbah A, Alshabanah M, AlSyaed A, Ajarim D, Al-Tweigeri T.

Breast J. 2017 Nov;23(6):775. doi: 10.1111/tbj.12826. Epub 2017 May 8. No abstract available.

PMID:
28481425
10.

Reduced rate of human papillomavirus infection and genetic overtransmission of TP53 72C polymorphic variant lower cervical cancer incidence.

Alsbeih GA, Al-Harbi NM, Bin Judia SS, Khoja HA, Shoukri MM, Tulbah AM.

Cancer. 2017 Jul 1;123(13):2459-2466. doi: 10.1002/cncr.30635. Epub 2017 Apr 10.

11.

Synovial sarcoma of the hard palate: The third case in the medical literature.

Doubi A, Doubi M, Alzaher N, Tulbah A.

Hematol Oncol Stem Cell Ther. 2017 Feb 1. pii: S1658-3876(17)30007-9. doi: 10.1016/j.hemonc.2016.12.005. [Epub ahead of print]

12.

Reply to "Letter to the Editor Concerning the Article-Impact of Surgery on Survival in Stage IV Breast Cancer".

Al Johani B, Al Malik O, Anwar E, Tulbah A, Alshabanah M, AlSayed A, Ajarim D, Al-Tweigeri T.

Breast J. 2017 Jan;23(1):119. doi: 10.1111/tbj.12701. Epub 2016 Oct 31. No abstract available.

PMID:
27797125
13.

Impact of Surgery on Survival in Stage IV Breast Cancer.

AlJohani B, AlMalik O, Anwar E, Tulbah A, Alshabanah M, AlSyaed A, Ajarim D, ALTweigeri T.

Breast J. 2016 Nov;22(6):678-682. doi: 10.1111/tbj.12662. Epub 2016 Aug 26.

PMID:
27564998
14.

Could simvastatin be considered as a potential therapy for chronic lung diseases? A debate on the pros and cons.

Tulbah AS, Ong HX, Colombo P, Young PM, Traini D.

Expert Opin Drug Deliv. 2016 Oct;13(10):1407-20. doi: 10.1080/17425247.2016.1193150. Epub 2016 Jun 6. Review.

PMID:
27212150
15.

Identification of novel BRCA founder mutations in Middle Eastern breast cancer patients using capture and Sanger sequencing analysis.

Bu R, Siraj AK, Al-Obaisi KA, Beg S, Al Hazmi M, Ajarim D, Tulbah A, Al-Dayel F, Al-Kuraya KS.

Int J Cancer. 2016 Sep 1;139(5):1091-7. doi: 10.1002/ijc.30143. Epub 2016 May 3.

16.

Sentinel lymph node biopsy in clinically detected ductal carcinoma in situ.

Al-Ameer AY, Al Nefaie S, Al Johani B, Anwar I, Al Tweigeri T, Tulbah A, Alshabanah M, Al Malik O.

World J Clin Oncol. 2016 Apr 10;7(2):258-64. doi: 10.5306/wjco.v7.i2.258.

17.

Sociodemographic characteristics and sexual behavior as risk factors for human papillomavirus infection in Saudi Arabia.

Alhamlan FS, Khayat HH, Ramisetty-Mikler S, Al-Muammar TA, Tulbah AM, Al-Badawi IA, Kurdi WI, Tulbah MI, Alkhenizan AA, Hussain AN, Ahmed M, Al-Ahdal MN.

Int J Infect Dis. 2016 May;46:94-9. doi: 10.1016/j.ijid.2016.04.004. Epub 2016 Apr 7.

18.

ALK alteration is a frequent event in aggressive breast cancers.

Siraj AK, Beg S, Jehan Z, Prabhakaran S, Ahmed M, R Hussain A, Al-Dayel F, Tulbah A, Ajarim D, Al-Kuraya KS.

Breast Cancer Res. 2015 Sep 17;17:127. doi: 10.1186/s13058-015-0610-3.

19.

Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: significance in claudin-low breast cancer cells.

Alsuliman A, Colak D, Al-Harazi O, Fitwi H, Tulbah A, Al-Tweigeri T, Al-Alwan M, Ghebeh H.

Mol Cancer. 2015 Aug 7;14:149. doi: 10.1186/s12943-015-0421-2.

20.

Biological Effects of Simvastatin Formulated as pMDI on Pulmonary Epithelial Cells.

Tulbah AS, Ong HX, Lee WH, Colombo P, Young PM, Traini D.

Pharm Res. 2016 Jan;33(1):92-101. doi: 10.1007/s11095-015-1766-3. Epub 2015 Aug 4.

PMID:
26238046
21.

Loss of PTEN expression is associated with aggressive behavior and poor prognosis in Middle Eastern triple-negative breast cancer.

Beg S, Siraj AK, Prabhakaran S, Jehan Z, Ajarim D, Al-Dayel F, Tulbah A, Al-Kuraya KS.

Breast Cancer Res Treat. 2015 Jun;151(3):541-53. doi: 10.1007/s10549-015-3430-3. Epub 2015 May 16.

PMID:
25981902
22.

Signet ring cell adenocarcinoma and bilateral leptomeningeal involvement of optic nerve sheaths.

Mbekeani JN, Haseeb MQ, Tulbah AM, Hamed SH, Al Hazzaa SA, Dogar MA.

J Neuroophthalmol. 2015 Jun;35(2):162-4. doi: 10.1097/WNO.0000000000000236.

PMID:
25839780
23.

Extrauterine epithelioid trophoblastic tumor arising in the ovary with multiple metastases: a case report.

Arafah MA, Tulbah AM, Al-Husaini H, Al-Sabban M, Al-Shankiti H, Al-Badawi IA.

Int J Surg Pathol. 2015 Jun;23(4):339-44. doi: 10.1177/1066896915570661. Epub 2015 Feb 18.

PMID:
25695493
24.

The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females.

Al-Moghrabi N, Nofel A, Al-Yousef N, Madkhali S, Bin Amer SM, Alaiya A, Shinwari Z, Al-Tweigeri T, Karakas B, Tulbah A, Aboussekhra A.

BMC Cancer. 2014 Nov 17;14:830. doi: 10.1186/1471-2407-14-830.

25.

Dry powder formulation of simvastatin.

Tulbah AS, Ong HX, Morgan L, Colombo P, Young PM, Traini D.

Expert Opin Drug Deliv. 2015 Jun;12(6):857-68. doi: 10.1517/17425247.2015.963054. Epub 2014 Sep 22.

PMID:
25244365
26.

Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway.

Ghebeh H, Al-Khaldi S, Olabi S, Al-Dhfyan A, Al-Mohanna F, Barnawi R, Tulbah A, Al-Tweigeri T, Ajarim D, Al-Alwan M.

Br J Cancer. 2014 Oct 14;111(8):1552-61. doi: 10.1038/bjc.2014.453. Epub 2014 Aug 12.

27.

Breast cancer: is there a viral connection?

Akhter J, Ali Aziz MA, Al Ajlan A, Tulbah A, Akhtar M.

Adv Anat Pathol. 2014 Sep;21(5):373-81. doi: 10.1097/PAP.0000000000000037. Review.

PMID:
25105938
28.

Novel simvastatin inhalation formulation and characterisation.

Tulbah AS, Ong HX, Colombo P, Young PM, Traini D.

AAPS PharmSciTech. 2014 Aug;15(4):956-62. doi: 10.1208/s12249-014-0127-6. Epub 2014 May 8.

29.

Isolated ureteric endometriosis presenting as a ureteric tumor.

Seyam R, Mokhtar A, Al Taweel W, Al Sayyah A, Tulbah A, Al Khudair W.

Urol Ann. 2014 Jan;6(1):94-7. doi: 10.4103/0974-7796.127035.

30.

Ovarian angiosarcoma: a case report and review of the literature.

Yaqoob N, Nemenqani D, Khoja H, Hafez M, Tulbah A, Al-Dayel F.

J Med Case Rep. 2014 Feb 12;8:47. doi: 10.1186/1752-1947-8-47.

31.

The journey toward personalized cancer therapy.

Tulbah A, Chaudhri N, Al Dayel F, Akhtar M.

Adv Anat Pathol. 2014 Jan;21(1):36-43. doi: 10.1097/PAP.0000000000000006. Review.

PMID:
24316909
32.

Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers.

Ghebeh H, Sleiman GM, Manogaran PS, Al-Mazrou A, Barhoush E, Al-Mohanna FH, Tulbah A, Al-Faqeeh K, Adra CN.

BMC Cancer. 2013 Jun 14;13:289. doi: 10.1186/1471-2407-13-289.

33.

Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women.

Colak D, Nofal A, Albakheet A, Nirmal M, Jeprel H, Eldali A, Al-Tweigeri T, Tulbah A, Ajarim D, Malik OA, Inan MS, Kaya N, Park BH, Bin Amer SM.

PLoS One. 2013 May 21;8(5):e63204. doi: 10.1371/journal.pone.0063204. Print 2013.

34.

A detailed study of patients and tumor characteristics of epithelial ovarian cancer in Saudi women.

Al-Badawi IA, Munkarah AR, Tulbah A, Babic II, Al Husaini H, Ahmad S.

Int J Gynecol Cancer. 2013 Mar;23(3):456-60. doi: 10.1097/IGC.0b013e318284aafe.

PMID:
23360812
35.

p16INK4A represses breast stromal fibroblasts migration/invasion and their VEGF-A-dependent promotion of angiogenesis through Akt inhibition.

Al-Ansari MM, Hendrayani SF, Tulbah A, Al-Tweigeri T, Shehata AI, Aboussekhra A.

Neoplasia. 2012 Dec;14(12):1269-77.

36.

The p53 codon 72 polymorphism is associated with risk and early onset of breast cancer among Saudi women.

Al-Qasem A, Toulimat M, Tulbah A, Elkum N, Al-Tweigeri T, Aboussekhra A.

Oncol Lett. 2012 Apr 1;3(4):875-878. Epub 2012 Jan 24.

37.

Fascin is a key regulator of breast cancer invasion that acts via the modification of metastasis-associated molecules.

Al-Alwan M, Olabi S, Ghebeh H, Barhoush E, Tulbah A, Al-Tweigeri T, Ajarim D, Adra C.

PLoS One. 2011;6(11):e27339. doi: 10.1371/journal.pone.0027339. Epub 2011 Nov 4.

38.

Detection and genotyping of human papilloma virus in cervical cancer specimens from Saudi patients.

Al-Badawi IA, Al-Suwaine A, Al-Aker M, Asaad L, Alaidan A, Tulbah A, Fe Bohol M, Munkarah AR.

Int J Gynecol Cancer. 2011 Jul;21(5):907-10. doi: 10.1097/IGC.0b013e318214219f.

PMID:
21697680
39.

Prevalence and genotypes' distribution of human papillomavirus in invasive cervical cancer in Saudi Arabia.

Alsbeih G, Ahmed R, Al-Harbi N, Venturina LA, Tulbah A, Balaraj K.

Gynecol Oncol. 2011 Jun 1;121(3):522-6. doi: 10.1016/j.ygyno.2011.01.033. Epub 2011 Feb 24.

PMID:
21353296
40.

TP53 genetic alterations in Arab breast cancer patients: Novel mutations, pattern and distribution.

Al-Qasem AJ, Toulimat M, Eldali AM, Tulbah A, Al-Yousef N, Al-Daihan SK, Al-Tassan N, Al-Tweigeri T, Aboussekhra A.

Oncol Lett. 2011 Mar;2(2):363-369. Epub 2011 Jan 18.

41.

Proteomics-based signature for human benign prostate hyperplasia and prostate adenocarcinoma.

Alaiya AA, Al-Mohanna M, Aslam M, Shinwari Z, Al-Mansouri L, Al-Rodayan M, Al-Eid M, Ahmad I, Hanash K, Tulbah A, Bin Mahfooz A, Adra C.

Int J Oncol. 2011 Apr;38(4):1047-57. doi: 10.3892/ijo.2011.937. Epub 2011 Feb 8.

PMID:
21305254
42.

Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule.

Ghebeh H, Lehe C, Barhoush E, Al-Romaih K, Tulbah A, Al-Alwan M, Hendrayani SF, Manogaran P, Alaiya A, Al-Tweigeri T, Aboussekhra A, Dermime S.

Breast Cancer Res. 2010;12(4):R48. doi: 10.1186/bcr2605. Epub 2010 Jul 13.

43.

Prospective phase II study of neoadjuvant doxorubicin followed by cisplatin/docetaxel in locally advanced breast cancer.

Al-Tweigeri TA, Ajarim DS, Alsayed AA, Rahal MM, Alshabanah MO, Tulbah AM, Al-Malik OA, Fatani DM, El-Husseiny GA, Elkum NB, Ezzat AA.

Med Oncol. 2010 Sep;27(3):571-7. doi: 10.1007/s12032-009-9251-7. Epub 2009 Jun 13.

PMID:
19526202
44.

Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes.

Hawsawi NM, Ghebeh H, Hendrayani SF, Tulbah A, Al-Eid M, Al-Tweigeri T, Ajarim D, Alaiya A, Dermime S, Aboussekhra A.

Cancer Res. 2008 Apr 15;68(8):2717-25. doi: 10.1158/0008-5472.CAN-08-0192.

45.

Gene expression profiling in women with breast cancer in a Saudi population.

Bin Amer SM, Maqbool Z, Nirmal MS, Qattan AT, Hussain SS, Jeprel HA, Tulbah AM, Malik OA, Al-Tweigeri TA.

Saudi Med J. 2008 Apr;29(4):507-13.

PMID:
18382789
46.

FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy.

Ghebeh H, Barhoush E, Tulbah A, Elkum N, Al-Tweigeri T, Dermime S.

BMC Cancer. 2008 Feb 23;8:57. doi: 10.1186/1471-2407-8-57.

47.

Clinicopathologic features of hepatic neoplasms in explanted livers: a single institution experience.

Mourad W, Khalaf H, Tulbah A, Al Omari M, Al Mana H, Neimatallah M.

Ann Saudi Med. 2007 Nov-Dec;27(6):437-41.

48.

Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: the Saudi Arabia experience.

Elkum N, Dermime S, Ajarim D, Al-Zahrani A, Alsayed A, Tulbah A, Al Malik O, Alshabanah M, Ezzat A, Al-Tweigeri T.

BMC Cancer. 2007 Dec 5;7:222.

49.

Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells.

Ghebeh H, Tulbah A, Mohammed S, Elkum N, Bin Amer SM, Al-Tweigeri T, Dermime S.

Int J Cancer. 2007 Aug 15;121(4):751-8.

50.

Multi-focal extra-uterine endometrial stromal sarcoma (ESS): a very rare complication of endometriosis associated with elevated serum CA-125.

Mourad WA, Abdelghaffar B, Tulbah A, Tulbah M, Subhi J.

Ann Saudi Med. 2003 May-Jul;23(3-4):181-3. No abstract available.

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