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Items: 1 to 50 of 170

1.

Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability.

Randolph JT, Krueger AC, Donner PL, Pratt JK, Liu D, Motter CE, Rockway TW, Tufano MD, Wagner R, Lim HB, Beyer JM, Mondal R, Panchal NS, Colletti L, Liu Y, Koev G, Kati WM, Hernandez LE, Beno DWA, Longenecker KL, Stewart KD, Dumas EO, Molla A, Maring CJ.

J Med Chem. 2018 Feb 8;61(3):1153-1163. doi: 10.1021/acs.jmedchem.7b01630. Epub 2018 Jan 25.

PMID:
29342358
2.

A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma.

D'Arrigo P, Russo M, Rea A, Tufano M, Guadagno E, Del Basso De Caro ML, Pacelli R, Hausch F, Staibano S, Ilardi G, Parisi S, Romano MF, Romano S.

Oncotarget. 2017 Jul 17;8(40):68291-68304. doi: 10.18632/oncotarget.19309. eCollection 2017 Sep 15.

3.

Do pediatric gastroenterology doctors address pediatric obesity?

Batra S, Yee C, Diez B, Nguyen N, Sheridan MJ, Tufano M, Sikka N, Townsend S, Hourigan S.

SAGE Open Med. 2017 Jul 26;5:2050312117722170. doi: 10.1177/2050312117722170. eCollection 2017.

4.

Transforming activities of Chlamydia pneumoniae in human mesothelial cells.

Rizzo A, Carratelli CR, De Filippis A, Bevilacqua N, Tufano MA, Buommino E.

Int Microbiol. 2014 Dec;17(4):185-93. doi: 10.2436/20.1501.01.221.

5.

Early onset Charcot-Marie-Tooth neuropathy type 2A and severe developmental delay: expanding the clinical phenotype of MFN2-related neuropathy.

Tufano M, Cappuccio G, Terrone G, Manganelli F, Pisciotta C, Geroldi A, Capponi S, Del Giudice E.

J Peripher Nerv Syst. 2015 Dec;20(4):415-8. doi: 10.1111/jns.12148.

PMID:
26307494
6.

Tissue resonance interaction accurately detects colon lesions: A double-blind pilot study.

Dore MP, Tufano MO, Pes GM, Cuccu M, Farina V, Manca A, Graham DY.

World J Gastroenterol. 2015 Jul 7;21(25):7851-9. doi: 10.3748/wjg.v21.i25.7851.

7.

Treatment of chronic hepatitis C in children with pegylated interferon and ribavirin: the impact of dose.

Tufano M, Pia Cicalese M, Immacolata Spagnuolo M, Terlizzi V, Iorio R.

Acta Gastroenterol Belg. 2015 Jan-Mar;78(1):8-11.

PMID:
26118572
8.

The role of chemotherapy and surgical removal in the treatment of Choroid Plexus carcinomas and atypical papillomas.

Passariello A, Tufano M, Spennato P, Quaglietta L, Verrico A, Migliorati R, Cinalli G.

Childs Nerv Syst. 2015 Jul;31(7):1079-88. doi: 10.1007/s00381-015-2697-3. Epub 2015 Apr 12.

PMID:
25863950
9.

Evaluation of a method based on coherence in aqueous systems and resonance-based isotherapeutic remedy in the treatment of chronic psoriasis vulgaris.

Del Giudice E, De Filippis A, Del Giudice N, Del Giudice M, d'Elia I, Iride L, Menghi E, Tedeschi A, Cozza V, Adone B, Tufano MA.

Curr Top Med Chem. 2015;15(6):542-8.

PMID:
25714381
10.

In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat).

Perfetto B, Filosa R, De Gregorio V, Peduto A, La Gatta A, de Caprariis P, Tufano MA, Donnarumma G.

J Med Microbiol. 2014 Nov;63(Pt 11):1474-83. doi: 10.1099/jmm.0.076612-0. Epub 2014 Sep 3.

PMID:
25187601
11.

Analysis of the response of human keratinocytes to Malassezia globosa and restricta strains.

Donnarumma G, Perfetto B, Paoletti I, Oliviero G, Clavaud C, Del Bufalo A, Guéniche A, Jourdain R, Tufano MA, Breton L.

Arch Dermatol Res. 2014 Oct;306(8):763-8. doi: 10.1007/s00403-014-1479-1. Epub 2014 Jul 20.

PMID:
25038621
12.

Effect of long-term GH treatment in a patient with CHARGE association.

Esposito A, Tufano M, Di Donato I, Rezzuto M, Improda N, Melis D, Salerno M.

Ital J Pediatr. 2014 Jun 2;40:51. doi: 10.1186/1824-7288-40-51.

13.

Discovery of ABT-267, a pan-genotypic inhibitor of HCV NS5A.

DeGoey DA, Randolph JT, Liu D, Pratt J, Hutchins C, Donner P, Krueger AC, Matulenko M, Patel S, Motter CE, Nelson L, Keddy R, Tufano M, Caspi DD, Krishnan P, Mistry N, Koev G, Reisch TJ, Mondal R, Pilot-Matias T, Gao Y, Beno DW, Maring CJ, Molla A, Dumas E, Campbell A, Williams L, Collins C, Wagner R, Kati WM.

J Med Chem. 2014 Mar 13;57(5):2047-57. doi: 10.1021/jm401398x. Epub 2014 Jan 15.

PMID:
24400777
14.

AlphaVBeta5 integrins mediates Pseudomonas fluorescens interaction with A549 cells

Buommino E, Di Domenico M, Paoletti I, Fusco A, De Gregorio V, Cozza V, Rizzo A, Tufano MA, Donnarumma G.

Front Biosci (Landmark Ed). 2014 Jan 1;19:408-15.

PMID:
24389192
15.

What evidence exists to support antiviral treatment in children with chronic hepatitis B?

Iorio R, Tufano M, Giagnorio MG, Spagnuolo MI, Giannattasio A.

Antivir Ther. 2014;19(3):225-7. doi: 10.3851/IMP2704. Epub 2013 Nov 5.

PMID:
24192644
16.

Constitutional 11q14-q22 chromosome deletion syndrome in a child with neuroblastoma MYCN single copy.

Passariello A, De Brasi D, Defferrari R, Genesio R, Tufano M, Mazzocco K, Capasso M, Migliorati R, Martinsson T, Siani P, Nitsch L, Tonini GP.

Eur J Med Genet. 2013 Nov;56(11):626-34. doi: 10.1016/j.ejmg.2013.08.005. Epub 2013 Sep 13.

PMID:
24035971
17.

Amygdalin analogues inhibit IFN-γ signalling and reduce the inflammatory response in human epidermal keratinocytes.

Paoletti I, De Gregorio V, Baroni A, Tufano MA, Donnarumma G, Perez JJ.

Inflammation. 2013 Dec;36(6):1316-26. doi: 10.1007/s10753-013-9670-7.

PMID:
23933845
18.

Design of inhibitors of influenza virus membrane fusion: synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series.

Brancato V, Peduto A, Wharton S, Martin S, More V, Di Mola A, Massa A, Perfetto B, Donnarumma G, Schiraldi C, Tufano MA, de Rosa M, Filosa R, Hay A.

Antiviral Res. 2013 Aug;99(2):125-35. doi: 10.1016/j.antiviral.2013.05.005. Epub 2013 May 22.

PMID:
23707194
19.

Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A.

DeGoey DA, Betebenner DA, Grampovnik DJ, Liu D, Pratt JK, Tufano MD, He W, Krishnan P, Pilot-Matias TJ, Marsh KC, Molla A, Kempf DJ, Maring CJ.

Bioorg Med Chem Lett. 2013 Jun 15;23(12):3627-30. doi: 10.1016/j.bmcl.2013.04.009. Epub 2013 Apr 10.

PMID:
23642966
20.

Synthesis of Substituted Isatins.

Klein LL, Tufano MD.

Tetrahedron Lett. 2013 Feb 1;54(8):1008-1011. Epub 2012 Dec 21.

21.

Efficacy of combined antiviral therapy with lamivudine and tenofovir in a liver transplanted girl with de novo hepatitis B virus infection.

Tufano M, Liccardo D, Riva S, Candusso M, Torre G, Iorio R.

Transpl Infect Dis. 2013 Apr;15(2):E81-4. doi: 10.1111/tid.12057. Epub 2013 Feb 6.

PMID:
23387823
22.

Innate immune response in human keratinocytes infected by a feline isolate of Malassezia pachydermatis.

Buommino E, De Filippis A, Parisi A, Nizza S, Martano M, Iovane G, Donnarumma G, Tufano MA, De Martino L.

Vet Microbiol. 2013 Apr 12;163(1-2):90-6. doi: 10.1016/j.vetmic.2012.12.001. Epub 2012 Dec 8.

PMID:
23273837
23.

The Helicobacter pylori protein HspB interferes with Nrf2/Keap1 pathway altering the antioxidant response of Ags cells.

Buommino E, Donnarumma G, Manente L, De Filippis A, Silvestri F, Iaquinto S, Tufano MA, De Luca A.

Helicobacter. 2012 Dec;17(6):417-25. doi: 10.1111/j.1523-5378.2012.00973.x. Epub 2012 Jul 11.

PMID:
23066931
24.

Polydatin, a natural precursor of resveratrol, induces β-defensin production and reduces inflammatory response.

Ravagnan G, De Filippis A, Cartenì M, De Maria S, Cozza V, Petrazzuolo M, Tufano MA, Donnarumma G.

Inflammation. 2013 Feb;36(1):26-34. doi: 10.1007/s10753-012-9516-8.

PMID:
22956122
25.

Modification of osteopontin and MMP-9 levels in patients with psoriasis on anti-TNF-α therapy.

Buommino E, De Filippis A, Gaudiello F, Balato A, Balato N, Tufano MA, Ayala F.

Arch Dermatol Res. 2012 Aug;304(6):481-5. doi: 10.1007/s00403-012-1251-3. Epub 2012 Jun 9.

PMID:
22684781
26.

Patenting Penicillium strains.

Nicoletti R, Buommino E, Tufano MA.

Recent Pat Biotechnol. 2012 Aug;6(2):81-96. Review.

PMID:
22642818
27.

Patented natural avocado sugar modulates the HBD-2 and HBD-3 expression in human keratinocytes through toll-like receptor-2 and ERK/MAPK activation.

Paoletti I, Buommino E, Fusco A, Baudouin C, Msika P, Tufano MA, Baroni A, Donnarumma G.

Arch Dermatol Res. 2012 Oct;304(8):619-25. doi: 10.1007/s00403-012-1237-1. Epub 2012 Apr 21.

PMID:
22526324
28.

Aurantoside J: a new tetramic acid glycoside from Theonella swinhoei. Insights into the antifungal potential of aurantosides.

Angawi RF, Bavestrello G, Calcinai B, Dien HA, Donnarumma G, Tufano MA, Paoletti I, Grimaldi E, Chianese G, Fattorusso E, Taglialatela-Scafati O.

Mar Drugs. 2011 Dec;9(12):2809-17. doi: 10.3390/md9122809. Epub 2011 Dec 20.

29.

Novel hepatitis C virus replicon inhibitors: synthesis and structure-activity relationships of fused pyrimidine derivatives.

Krueger AC, Madigan DL, Beno DW, Betebenner DA, Carrick R, Green BE, He W, Liu D, Maring CJ, McDaniel KF, Mo H, Molla A, Motter CE, Pilot-Matias TJ, Tufano MD, Kempf DJ.

Bioorg Med Chem Lett. 2012 Mar 15;22(6):2212-5. doi: 10.1016/j.bmcl.2012.01.096. Epub 2012 Feb 2.

PMID:
22342631
30.

3-O-methylfunicone, from Penicillium pinophilum, is a selective inhibitor of breast cancer stem cells.

Buommino E, Tirino V, De Filippis A, Silvestri F, Nicoletti R, Ciavatta ML, Pirozzi G, Tufano MA.

Cell Prolif. 2011 Oct;44(5):401-9. doi: 10.1111/j.1365-2184.2011.00766.x.

PMID:
21951283
31.

Dry powders based on PLGA nanoparticles for pulmonary delivery of antibiotics: modulation of encapsulation efficiency, release rate and lung deposition pattern by hydrophilic polymers.

Ungaro F, d'Angelo I, Coletta C, d'Emmanuele di Villa Bianca R, Sorrentino R, Perfetto B, Tufano MA, Miro A, La Rotonda MI, Quaglia F.

J Control Release. 2012 Jan 10;157(1):149-59. doi: 10.1016/j.jconrel.2011.08.010. Epub 2011 Aug 16.

PMID:
21864595
32.

Cell-growth and migration inhibition of human mesothelioma cells induced by 3-O-methylfunicone from Penicillium pinophilum and cisplatin.

Buommino E, De Filippis A, Nicoletti R, Menegozzo M, Menegozzo S, Ciavatta ML, Rizzo A, Brancato V, Tufano MA, Donnarumma G.

Invest New Drugs. 2012 Aug;30(4):1343-51. doi: 10.1007/s10637-011-9698-1. Epub 2011 Jun 9.

PMID:
21656164
33.

Captopril modulates acetylcholinesterase in human keratinocytes.

Baroni A, Buommino E, Ruocco E, Petrazzuolo M, De Filippis A, Satriano RA, Ruocco V, Cozza V, Tufano MA.

Arch Dermatol Res. 2011 Sep;303(7):491-7. doi: 10.1007/s00403-011-1124-1. Epub 2011 Feb 1.

PMID:
21286734
34.

Effects of toluidine blue-mediated photodynamic therapy on periopathogens and periodontal biofilm: in vitro evaluation.

Nastri L, Donnarumma G, Porzio C, De Gregorio V, Tufano MA, Caruso F, Mazza C, Serpico R.

Int J Immunopathol Pharmacol. 2010 Oct-Dec;23(4):1125-32.

PMID:
21244761
35.

AV119, a natural sugar from avocado gratissima, modulates the LPS-induced proinflammatory response in human keratinocytes.

Donnarumma G, Paoletti I, Buommino E, Fusco A, Baudouin C, Msika P, Tufano MA, Baroni A.

Inflammation. 2011 Dec;34(6):568-75. doi: 10.1007/s10753-010-9264-6.

PMID:
20936426
36.

Fulminant hepatic failure requiring liver transplantation in 22q13.3 deletion syndrome.

Bartsch O, Schneider E, Damatova N, Weis R, Tufano M, Iorio R, Ahmed A, Beyer V, Zechner U, Haaf T.

Am J Med Genet A. 2010 Aug;152A(8):2099-102. doi: 10.1002/ajmg.a.33542.

PMID:
20635403
37.

Antibiotic susceptibility of respiratory pathogens recently isolated in Italy: focus on cefditoren.

Tempera G, Furneri PM, Carlone NA, Cocuzza C, Rigoli R, Musumeci R, Pilloni AP, Prenna M, Tufano MA, Tullio V, Vitali LA, Nicoletti G.

J Chemother. 2010 Jun;22(3):153-9.

38.

3-O-Methylfunicone, a metabolite produced by Penicillium pinophilum, modulates ERK1/2 activity, affecting cell motility of human mesothelioma cells.

Buommino E, Paoletti I, De Filippis A, Nicoletti R, Ciavatta ML, Menegozzo S, Menegozzo M, Tufano MA.

Cell Prolif. 2010 Apr;43(2):114-23. doi: 10.1111/j.1365-2184.2010.00663.x.

PMID:
20447056
39.

Effect of metronidazole and modulation of cytokine production on human periodontal ligament cells.

Rizzo A, Paolillo R, Guida L, Annunziata M, Bevilacqua N, Tufano MA.

Int Immunopharmacol. 2010 Jul;10(7):744-50. doi: 10.1016/j.intimp.2010.04.004. Epub 2010 Apr 22.

PMID:
20399284
40.

Effect of temperature on the shift of Pseudomonas fluorescens from an environmental microorganism to a potential human pathogen.

Donnarumma G, Buommino E, Fusco A, Paoletti I, Auricchio L, Tufano MA.

Int J Immunopathol Pharmacol. 2010 Jan-Mar;23(1):227-34.

PMID:
20378008
41.

Autoimmune hepatitis type 2 arising in PFAPA syndrome: coincidences or possible correlations?

Della Corte C, Ranucci G, Tufano M, Alessio M, Iorio R.

Pediatrics. 2010 Mar;125(3):e683-6. doi: 10.1542/peds.2009-2630. Epub 2010 Feb 8.

PMID:
20142286
42.

Methicillin-resistant staphylococci isolated from healthy horses and horse personnel in Italy.

De Martino L, Lucido M, Mallardo K, Facello B, Mallardo M, Iovane G, Pagnini U, Tufano MA, Catalanotti P.

J Vet Diagn Invest. 2010 Jan;22(1):77-82.

PMID:
20093688
43.

Hepatocyte growth factor (HGF) modulates Leydig cell extracellular matrix components.

Catizone A, Ricci G, Tufano MA, Perfetto B, Canipari R, Galdieri M.

J Androl. 2010 May-Jun;31(3):306-13. doi: 10.2164/jandrol.109.007658. Epub 2009 Oct 15.

44.

Patented natural avocado sugars modulate the HBD-2 expression in human keratinocytes through the involvement of protein kinase C and protein tyrosine kinases.

Paoletti I, Buommino E, Tudisco L, Baudouin C, Msika P, Tufano MA, Baroni A, Donnarumma G.

Arch Dermatol Res. 2010 Apr;302(3):201-9. doi: 10.1007/s00403-009-0991-1. Epub 2009 Sep 16.

PMID:
19760202
45.

Cholestasis in neonatal intensive care unit: incidence, aetiology and management.

Tufano M, Nicastro E, Giliberti P, Vegnente A, Raimondi F, Iorio R.

Acta Paediatr. 2009 Nov;98(11):1756-61. doi: 10.1111/j.1651-2227.2009.01464.x. Epub 2009 Aug 6.

PMID:
19664101
46.

3-O-methylfunicone, a metabolite of Penicillium pinophilum, inhibits proliferation of human melanoma cells by causing G(2) + M arrest and inducing apoptosis.

Baroni A, De Luca A, De Filippis A, Petrazzuolo M, Manente L, Nicoletti R, Tufano MA, Buommino E.

Cell Prolif. 2009 Aug;42(4):541-53. doi: 10.1111/j.1365-2184.2009.00609.x. Epub 2009 May 22.

PMID:
19486013
47.

Osteopontin: a new emerging role in psoriasis.

Buommino E, Tufano MA, Balato N, Canozo N, Donnarumma M, Gallo L, Balato A, Ayala F.

Arch Dermatol Res. 2009 Jul;301(6):397-404. doi: 10.1007/s00403-009-0939-5. Epub 2009 Mar 20.

PMID:
19301019
48.

Antimicrobial human beta-defensin-2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells.

Baroni A, Donnarumma G, Paoletti I, Longanesi-Cattani I, Bifulco K, Tufano MA, Carriero MV.

Peptides. 2009 Feb;30(2):267-72. doi: 10.1016/j.peptides.2008.11.001. Epub 2008 Nov 12.

PMID:
19041917
49.

Antibacterial activity of cefditoren against major community-acquired respiratory pathogens recently isolated in Italy.

Stefani S, Mezzatesta ML, Fadda G, Mattina R, Palù G, Rossano F, Tufano MA, Schito GC, Nicoletti G.

J Chemother. 2008 Oct;20(5):561-9.

PMID:
19028617
50.

Artemisinin reduces human melanoma cell migration by down-regulating alpha V beta 3 integrin and reducing metalloproteinase 2 production.

Buommino E, Baroni A, Canozo N, Petrazzuolo M, Nicoletti R, Vozza A, Tufano MA.

Invest New Drugs. 2009 Oct;27(5):412-8. doi: 10.1007/s10637-008-9188-2. Epub 2008 Oct 28.

PMID:
18956140

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