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Investigating strategies to improve clinical trial opportunities for patients with cancer in New Zealand-INSIGHT.

So YJ, Jameson M, Newton V, O'Donnell A, Jeffery M, Jackson C, Tuck A, Gregory K, North R, Anderson M, Sharples K, Findlay M, Wilson MK.

N Z Med J. 2019 Jul 12;132(1498):10-31.


Human placental androgen receptor variants: Potential regulators of male fetal growth.

Meakin AS, Saif Z, Tuck AR, Clifton VL.

Placenta. 2019 May;80:18-26. doi: 10.1016/j.placenta.2019.03.012. Epub 2019 Mar 26.


Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes.

Repouskou A, Panagiotidou E, Panagopoulou L, Bisting PL, Tuck AR, Sjödin MOD, Lindberg J, Bozas E, Rüegg J, Gennings C, Bornehag CG, Damdimopoulou P, Stamatakis A, Kitraki E.

Sci Rep. 2019 Apr 23;9(1):6424. doi: 10.1038/s41598-019-42377-6.


Drivers of year-to-year variation in exacerbation frequency of COPD: analysis of the AERIS cohort.

Wilkinson TMA, Aris E, Bourne SC, Clarke SC, Peeters M, Pascal TG, Taddei L, Tuck AC, Kim VL, Ostridge KK, Staples KJ, Williams NP, Williams AP, Wootton SA, Devaster JM.

ERJ Open Res. 2019 Feb 25;5(1). pii: 00248-2018. doi: 10.1183/23120541.00248-2018. eCollection 2019 Feb.


TBX3 promotes progression of pre-invasive breast cancer cells by inducing EMT and directly up-regulating SLUG.

Krstic M, Kolendowski B, Cecchini MJ, Postenka CO, Hassan HM, Andrews J, MacMillan CD, Williams KC, Leong HS, Brackstone M, Torchia J, Chambers AF, Tuck AB.

J Pathol. 2019 Jun;248(2):191-203. doi: 10.1002/path.5245. Epub 2019 Apr 8.


Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis.

Williams KC, Cepeda MA, Javed S, Searle K, Parkins KM, Makela AV, Hamilton AM, Soukhtehzari S, Kim Y, Tuck AB, Ronald JA, Foster PJ, Chambers AF, Leong HS.

Oncogene. 2019 May;38(19):3598-3615. doi: 10.1038/s41388-018-0667-4. Epub 2019 Jan 16.


Unmet Health Care Needs for Syrian Refugees in Canada: A Follow-up Study.

Tuck A, Oda A, Hynie M, Bennett-AbuAyyash C, Roche B, Agic B, McKenzie K.

J Immigr Minor Health. 2019 Jan 8. doi: 10.1007/s10903-019-00856-y. [Epub ahead of print]


Distinctive features of lincRNA gene expression suggest widespread RNA-independent functions.

Tuck AC, Natarajan KN, Rice GM, Borawski J, Mohn F, Rankova A, Flemr M, Wenger A, Nutiu R, Teichmann S, Bühler M.

Life Sci Alliance. 2018 Jul 31;1(4):e201800124. doi: 10.26508/lsa.201800124. eCollection 2018 Aug.


A high-throughput system used to determine frequency and distribution of phosphine resistance across large geographical regions.

Schlipalius DI, Tuck AG, Pavic H, Daglish GJ, Nayak MK, Ebert PR.

Pest Manag Sci. 2019 Apr;75(4):1091-1098. doi: 10.1002/ps.5221. Epub 2018 Nov 2.


Evaluation of Clinical Prognostic Factors and Further Delineation of the Effect of Mesenteric Fibrosis on Survival in Advanced Midgut Neuroendocrine Tumours.

Laskaratos FM, Walker M, Wilkins D, Tuck A, Ramakrishnan S, Phillips E, Gertner J, Megapanou M, Papantoniou D, Shah R, Banks J, Vlachou E, Garcia-Hernandez J, Woodbridge L, Papadopoulou A, Grant L, Theocharidou E, Watkins J, Luong TV, Mandair D, Caplin M, Toumpanakis C.

Neuroendocrinology. 2018;107(3):292-304. doi: 10.1159/000493317. Epub 2018 Aug 28.


Impact of radiologically stratified exacerbations: insights into pneumonia aetiology in COPD.

Williams NP, Ostridge K, Devaster JM, Kim V, Coombs NA, Bourne S, Clarke SC, Harden S, Abbas A, Aris E, Lambert C, Tuck A, Williams A, Wootton S, Staples KJ, Wilkinson TMA; AERIS Study Group.

Respir Res. 2018 Jul 28;19(1):143. doi: 10.1186/s12931-018-0842-8.


The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion.

Noonan MM, Dragan M, Mehta MM, Hess DA, Brackstone M, Tuck AB, Viswakarma N, Rana A, Babwah AV, Wondisford FE, Bhattacharya M.

Oncotarget. 2018 Jul 10;9(53):30034-30052. doi: 10.18632/oncotarget.25682. eCollection 2018 Jul 10.


Role of osteopontin as a predictive biomarker for anti-EGFR therapy in triple-negative breast cancer.

Anborgh PH, Lee DJ, Stam PF, Tuck AB, Chambers AF.

Expert Opin Ther Targets. 2018 Aug;22(8):727-734. doi: 10.1080/14728222.2018.1502272. Epub 2018 Jul 26.


Differences in Self-Reported Health and Unmet Health Needs Between Government Assisted and Privately Sponsored Syrian Refugees: A Cross-Sectional Survey.

Oda A, Hynie M, Tuck A, Agic B, Roche B, McKenzie K.

J Immigr Minor Health. 2019 Jun;21(3):439-442. doi: 10.1007/s10903-018-0780-z.


Ecology and diversity in upper respiratory tract microbial population structures from a cross-sectional community swabbing study.

Coughtrie AL, Morris DE, Anderson R, Begum N, Cleary DW, Faust SN, Jefferies JM, Kraaijeveld AR, Moore MV, Mullee MA, Roderick PJ, Tuck A, Whittaker RN, Yuen HM, Doncaster CP, Clarke SC.

J Med Microbiol. 2018 Aug;67(8):1096-1108. doi: 10.1099/jmm.0.000773. Epub 2018 Jun 21.


A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits.

Rouvière JO, Bulfoni M, Tuck A, Cosson B, Devaux F, Palancade B.

Nat Commun. 2018 Apr 25;9(1):1665. doi: 10.1038/s41467-018-03673-3.


Variant Linkage Analysis Using de Novo Transcriptome Sequencing Identifies a Conserved Phosphine Resistance Gene in Insects.

Schlipalius DI, Tuck AG, Jagadeesan R, Nguyen T, Kaur R, Subramanian S, Barrero R, Nayak M, Ebert PR.

Genetics. 2018 May;209(1):281-290. doi: 10.1534/genetics.118.300688. Epub 2018 Mar 1.


Relationship of CT-quantified emphysema, small airways disease and bronchial wall dimensions with physiological, inflammatory and infective measures in COPD.

Ostridge K, Williams NP, Kim V, Harden S, Bourne S, Clarke SC, Aris E, Mesia-Vela S, Devaster JM, Tuck A, Williams A, Wootton S, Staples KJ, Wilkinson TMA; AERIS Study Group.

Respir Res. 2018 Feb 20;19(1):31. doi: 10.1186/s12931-018-0734-y.


Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations.

Mayhew D, Devos N, Lambert C, Brown JR, Clarke SC, Kim VL, Magid-Slav M, Miller BE, Ostridge KK, Patel R, Sathe G, Simola DF, Staples KJ, Sung R, Tal-Singer R, Tuck AC, Van Horn S, Weynants V, Williams NP, Devaster JM, Wilkinson TMA; AERIS Study Group.

Thorax. 2018 May;73(5):422-430. doi: 10.1136/thoraxjnl-2017-210408. Epub 2018 Jan 31.


Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization.

Kolendowski B, Hassan H, Krstic M, Isovic M, Thillainadesan G, Chambers AF, Tuck AB, Torchia J.

Epigenetics Chromatin. 2018 Jan 29;11(1):5. doi: 10.1186/s13072-018-0176-2.


The 9-Item Patient Health Questionnaire (PHQ-9): an aid to assessment of patient-reported functional outcomes after spinal surgery.

Tuck AN, Scribani MB, Grainger SD, Johns CA, Knight RQ.

Spine J. 2018 Aug;18(8):1398-1405. doi: 10.1016/j.spinee.2018.01.004. Epub 2018 Jan 31.


Resveratrol supports and alpha-naphthoflavone disrupts growth of human ovarian follicles in an in vitro tissue culture model.

Hao J, Tuck AR, Sjödin MOD, Lindberg J, Sand A, Niklasson B, Argyraki M, Hovatta O, Damdimopoulou P.

Toxicol Appl Pharmacol. 2018 Jan 1;338:73-82. doi: 10.1016/j.taap.2017.11.009. Epub 2017 Nov 14.


RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit.

Milligan L, Sayou C, Tuck A, Auchynnikava T, Reid JE, Alexander R, Alves FL, Allshire R, Spanos C, Rappsilber J, Beggs JD, Kudla G, Tollervey D.

Elife. 2017 Oct 13;6. pii: e27082. doi: 10.7554/eLife.27082.


Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort.

Kim VL, Coombs NA, Staples KJ, Ostridge KK, Williams NP, Wootton SA, Devaster JM, Aris E, Clarke SC, Tuck AC, Bourne SC, Wilkinson TMA; AERIS Study Group.

Eur Respir J. 2017 Oct 12;50(4). pii: 1700853. doi: 10.1183/13993003.00853-2017. Print 2017 Oct.


Minimally Invasive Palmaris Longus Abductorplasty for Severe Carpal Tunnel Syndrome.

Chung SR, Yap RT, Tuck AYK.

Tech Hand Up Extrem Surg. 2017 Dec;21(4):149-154. doi: 10.1097/BTH.0000000000000176.


Concurrent Neoadjuvant Chemotherapy and Radiation Therapy in Locally Advanced Breast Cancer.

Brackstone M, Palma D, Tuck AB, Scott L, Potvin K, Vandenberg T, Perera F, D'Souza D, Taves D, Kornecki A, Muscedere G, Chambers AF.

Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):769-776. doi: 10.1016/j.ijrobp.2017.06.005. Epub 2017 Jun 20.


Proposed Empirical Entropy and Gibbs Energy Based on Observations of Scale Invariance in Open Nonequilibrium Systems.

Tuck AF.

J Phys Chem A. 2017 Sep 7;121(35):6620-6629. doi: 10.1021/acs.jpca.7b03112. Epub 2017 Aug 24.


Omitting radiation therapy after lumpectomy for pure DCIS does not reduce the risk of salvage mastectomy.

Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Gu S, Fong C, Tuck A, Youngson B, Miller N, Done SJ, Chang MC, Sengupta S, Elavathil L, Jani PA, Bonin M, Lalani N, Paszat L.

Breast. 2018 Feb;37:181-186. doi: 10.1016/j.breast.2017.07.002. Epub 2017 Aug 3.


Past year cannabis use and problematic cannabis use among adults by ethnicity in Ontario.

Tuck A, Hamilton HA, Agic B, Ialomiteanu AR, Mann RE.

Drug Alcohol Depend. 2017 Oct 1;179:93-99. doi: 10.1016/j.drugalcdep.2017.06.022. Epub 2017 Jul 20.


Health care needs and use of health care services among newly arrived Syrian refugees: a cross-sectional study.

Oda A, Tuck A, Agic B, Hynie M, Roche B, McKenzie K.

CMAJ Open. 2017 May 3;5(2):E354-E358. doi: 10.9778/cmajo.20160170.


Correction: Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD.

Staples KJ, Taylor S, Thomas S, Leung S, Cox K, Pascal TG, Ostridge K, Welch L, Tuck AC, Clarke SC, Gorringe A, Wilkinson TMA.

PLoS One. 2017 Apr 25;12(4):e0176749. doi: 10.1371/journal.pone.0176749. eCollection 2017.


A prospective, observational cohort study of the seasonal dynamics of airway pathogens in the aetiology of exacerbations in COPD.

Wilkinson TMA, Aris E, Bourne S, Clarke SC, Peeters M, Pascal TG, Schoonbroodt S, Tuck AC, Kim V, Ostridge K, Staples KJ, Williams N, Williams A, Wootton S, Devaster JM; AERIS Study Group.

Thorax. 2017 Oct;72(10):919-927. doi: 10.1136/thoraxjnl-2016-209023. Epub 2017 Apr 21.


G protein-coupled KISS1 receptor is overexpressed in triple negative breast cancer and promotes drug resistance.

Blake A, Dragan M, Tirona RG, Hardy DB, Brackstone M, Tuck AB, Babwah AV, Bhattacharya M.

Sci Rep. 2017 Apr 19;7:46525. doi: 10.1038/srep46525.


The role of ethnicity in pathways to emergency psychiatric services for clients with psychosis.

Rotenberg M, Tuck A, Ptashny R, McKenzie K.

BMC Psychiatry. 2017 Apr 13;17(1):137. doi: 10.1186/s12888-017-1285-3.


Multigene Expression Assay and Benefit of Radiotherapy After Breast Conservation in Ductal Carcinoma in Situ.

Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Baehner FL, Miller DP, Fong C, Gu S, Tuck A, Sengupta S, Elavathil L, Jani PA, Bonin M, Chang MC, Slodkowska E, Anderson JM, Cherbavaz DB, Shak S, Paszat L.

J Natl Cancer Inst. 2017 Apr 1;109(4). doi: 10.1093/jnci/djw256.


Nuclear RNA Decay Pathways Aid Rapid Remodeling of Gene Expression in Yeast.

Bresson S, Tuck A, Staneva D, Tollervey D.

Mol Cell. 2017 Mar 2;65(5):787-800.e5. doi: 10.1016/j.molcel.2017.01.005. Epub 2017 Feb 9.


The rise and fall of pneumococcal serotypes carried in the PCV era.

Devine VT, Cleary DW, Jefferies JM, Anderson R, Morris DE, Tuck AC, Gladstone RA, O'Doherty G, Kuruparan P, Bentley SD, Faust SN, Clarke SC.

Vaccine. 2017 Mar 1;35(9):1293-1298. doi: 10.1016/j.vaccine.2017.01.035. Epub 2017 Feb 1.


Religion, Alcohol Use and Risk Drinking Among Canadian Adults Living in Ontario.

Tuck A, Robinson M, Agic B, Ialomiteanu AR, Mann RE.

J Relig Health. 2017 Dec;56(6):2023-2038. doi: 10.1007/s10943-016-0339-z.


Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD.

Staples KJ, Taylor S, Thomas S, Leung S, Cox K, Pascal TG, Ostridge K, Welch L, Tuck AC, Clarke SC, Gorringe A, Wilkinson TM.

PLoS One. 2016 Nov 29;11(11):e0167250. doi: 10.1371/journal.pone.0167250. eCollection 2016. Erratum in: PLoS One. 2017 Apr 25;12 (4):e0176749.


Psychiatry, Connecting with Patients, and the Art of Failure.

Tuck A.

Acad Psychiatry. 2016 Dec;40(6):950-952. Epub 2016 Nov 2. No abstract available.


The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer.

Krstic M, Macmillan CD, Leong HS, Clifford AG, Souter LH, Dales DW, Postenka CO, Chambers AF, Tuck AB.

BMC Cancer. 2016 Aug 23;16(1):671. doi: 10.1186/s12885-016-2697-z.


Strand-specific, high-resolution mapping of modified RNA polymerase II.

Milligan L, Huynh-Thu VA, Delan-Forino C, Tuck A, Petfalski E, Lombraña R, Sanguinetti G, Kudla G, Tollervey D.

Mol Syst Biol. 2016 Jun 10;12(6):874. doi: 10.15252/msb.20166869.


Primary melanoma tumor inhibits metastasis through alterations in systemic hemostasis.

Kirstein JM, Hague MN, McGowan PM, Tuck AB, Chambers AF.

J Mol Med (Berl). 2016 Aug;94(8):899-910. doi: 10.1007/s00109-016-1415-2. Epub 2016 Apr 6.


In utero Programming of Allergic Susceptibility.

Grieger JA, Clifton VL, Tuck AR, Wooldridge AL, Robertson SA, Gatford KL.

Int Arch Allergy Immunol. 2016;169(2):80-92. doi: 10.1159/000443961. Epub 2016 Apr 5. Review.


Gender differences in pathways to care for early psychosis.

Ferrari M, Flora N, Anderson KK, Haughton A, Tuck A, Archie S, Kidd S, McKenzie K; ACE Project Team.

Early Interv Psychiatry. 2018 Jun;12(3):355-361. doi: 10.1111/eip.12324. Epub 2016 Mar 28.


Comparative analysis of pathways to early intervention services and duration of untreated psychosis in two Canadian cities.

Flora N, Anderson KK, Ferrari M, Tuck A, Archie S, Kidd S, McKenzie K; behalf of the ACE Project Team.

Early Interv Psychiatry. 2017 Dec;11(6):517-521. doi: 10.1111/eip.12326. Epub 2016 Mar 9.


Do group-specific equations provide the best estimates of stature?

Albanese J, Osley SE, Tuck A.

Forensic Sci Int. 2016 Apr;261:154-8. doi: 10.1016/j.forsciint.2016.02.019. Epub 2016 Feb 17.


An alternative approach for estimating stature from long bones that is not population- or group-specific.

Albanese J, Tuck A, Gomes J, Cardoso HF.

Forensic Sci Int. 2016 Feb;259:59-68. doi: 10.1016/j.forsciint.2015.12.011. Epub 2015 Dec 19.


Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough.

Holmes RK, Tuck AC, Zhu C, Dunn-Davies HR, Kudla G, Clauder-Munster S, Granneman S, Steinmetz LM, Guthrie C, Tollervey D.

PLoS Genet. 2015 Dec 22;11(12):e1005735. doi: 10.1371/journal.pgen.1005735. eCollection 2015 Dec.

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