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Tumor-specific delivery of gemcitabine with activatable liposomes.

Tucci ST, Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Foiret J, Hubbard NE, Borowsky AD, Baikoghli M, Cheng RH, Ferrara KW.

J Control Release. 2019 Jul 10. pii: S0168-3659(19)30401-8. doi: 10.1016/j.jconrel.2019.07.014. [Epub ahead of print]


The long walk to African genomics.

Tucci S, Akey JM.

Genome Biol. 2019 Jun 27;20(1):130. doi: 10.1186/s13059-019-1740-1. No abstract available.


Implementation of a fast method for the measurement of carnitine palmitoyltransferase 2 activity in lymphocytes by tandem mass spectrometry as confirmation for newborn screening.

Tucci S, Behringer S, Sturm M, Grünert SC, Spiekerkoetter U.

J Inherit Metab Dis. 2019 Apr 8. doi: 10.1002/jimd.12098. [Epub ahead of print]


A Scalable Method for Squalenoylation and Assembly of Multifunctional 64Cu-Labeled Squalenoylated Gemcitabine Nanoparticles.

Tucci ST, Seo JW, Kakwere H, Kheirolomoom A, Ingham ES, Mahakian LM, Tam S, Tumbale S, Baikoghli M, Cheng RH, Ferrara KW.

Nanotheranostics. 2018 Sep 5;2(4):387-402. doi: 10.7150/ntno.26969. eCollection 2018.


Histogram Analysis of Adrenal Lesions With a Single Measurement for 10th Percentile: Feasibility and Incremental Value for Diagnosing Adenomas.

Rocha TO, Albuquerque TC, Nather JC Jr, Salmon CEG, Tucci S Jr, Wang JZ, Westphalen AC, Elias J Jr, Muglia VF.

AJR Am J Roentgenol. 2018 Dec;211(6):1227-1233. doi: 10.2214/AJR.17.19159. Epub 2018 Oct 9.


The diagnostic challenge in very-long chain acyl-CoA dehydrogenase deficiency (VLCADD).

Hesse J, Braun C, Behringer S, Matysiak U, Spiekerkoetter U, Tucci S.

J Inherit Metab Dis. 2018 Nov;41(6):1169-1178. doi: 10.1007/s10545-018-0245-5. Epub 2018 Sep 7.


Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia.

Tucci S, Vohr SH, McCoy RC, Vernot B, Robinson MR, Barbieri C, Nelson BJ, Fu W, Purnomo GA, Sudoyo H, Eichler EE, Barbujani G, Visscher PM, Akey JM, Green RE.

Science. 2018 Aug 3;361(6401):511-516. doi: 10.1126/science.aar8486.


Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture.

Browning SR, Browning BL, Zhou Y, Tucci S, Akey JM.

Cell. 2018 Mar 22;173(1):53-61.e9. doi: 10.1016/j.cell.2018.02.031. Epub 2018 Mar 15.


Five Years of Journal Clubs With Pediatric Nurses and Allied Health Professionals: A Retrospective Study and Satisfaction Survey.

Dall'Oglio I, Vanzi V, Tiozzo E, Gawronski O, Biagioli V, Tucci S, Raponi M.

J Pediatr Nurs. 2018 Mar 15. pii: S0882-5963(17)30562-6. doi: 10.1016/j.pedn.2018.03.003. [Epub ahead of print]


Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.

Li Y, Sekula P, Wuttke M, Wahrheit J, Hausknecht B, Schultheiss UT, Gronwald W, Schlosser P, Tucci S, Ekici AB, Spiekerkoetter U, Kronenberg F, Eckardt KU, Oefner PJ, Köttgen A; GCKD Investigators.

J Am Soc Nephrol. 2018 May;29(5):1513-1524. doi: 10.1681/ASN.2017101099. Epub 2018 Mar 15.


Expression profile of endothelin receptors (ETA and ETB) and microRNAs-155 and -199 in the corpus cavernosum of rats submitted to chronic alcoholism and diabetes mellitus.

Gonçalves FZ, Lizarte Neto FS, Novais PC, Gattas D, Lourenço LG, de Carvalho CAM, Tirapelli DPC, Molina CAF, Tirapelli LF, Tucci S Jr.

Braz J Med Biol Res. 2018 Mar 1;51(3):e6329. doi: 10.1590/1414-431X20176329.


Mitochondrial fatty acid biosynthesis and muscle fiber plasticity in very long-chain acyl-CoA dehydrogenase-deficient mice.

Tucci S, Mingirulli N, Wehbe Z, Dumit VI, Kirschner J, Spiekerkoetter U.

FEBS Lett. 2018 Jan;592(2):219-232. doi: 10.1002/1873-3468.12940. Epub 2018 Jan 4.


Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy.

Azevedo AMM, Brites-Anselmi G, Pinheiro LC, de Almeida Belo V, Coeli-Lacchini FB, Molina CAF, de Andrade MF, Tucci S Jr, Hirsch E, Tanus-Santos JE, Lacchini R.

Nitric Oxide. 2017 Dec 1;71:44-51. doi: 10.1016/j.niox.2017.10.006. Epub 2017 Oct 23.


Leptin concentrations and SCD-1 indices in classical homocystinuria: Evidence for the role of sulfur amino acids in the regulation of lipid metabolism.

Poloni S, Spritzer PM, Mendes RH, D'Almeida V, Castro K, Sperb-Ludwig F, Kugele J, Tucci S, Blom HJ, Schwartz IVD.

Clin Chim Acta. 2017 Oct;473:82-88. doi: 10.1016/j.cca.2017.08.005. Epub 2017 Aug 8.


Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.

Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci ST, Watson KD, Wong AW, Monjazeb AM, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW.

JCI Insight. 2017 Mar 23;2(6):e90521. doi: 10.1172/jci.insight.90521.


Very long-chain acyl-CoA dehydrogenase (VLCAD-) deficiency-studies on treatment effects and long-term outcomes in mouse models.

Tucci S.

J Inherit Metab Dis. 2017 May;40(3):317-323. doi: 10.1007/s10545-017-0016-8. Epub 2017 Feb 28. Review.


Adrenocortical neoplasms in adulthood and childhood: distinct presentation. Review of the clinical, pathological and imaging characteristics.

Melo-Leite AF, Elias PC, Teixeira SR, Tucci S, Barros GE, Antonini SR, Muglia VF, Elias J.

J Pediatr Endocrinol Metab. 2017 Mar 1;30(3):253-276. doi: 10.1515/jpem-2016-0080. Review.


Superficial vein thrombosis in non-varicose veins of the lower limbs and thrombophilia.

Lucchi G, Bilancini S, Tucci S, Lucchi M.

Phlebology. 2018 May;33(4):278-281. doi: 10.1177/0268355517690643. Epub 2017 Jan 29.


Triheptanoin: long-term effects in the very long-chain acyl-CoA dehydrogenase-deficient mouse.

Tucci S, Floegel U, Beermann F, Behringer S, Spiekerkoetter U.

J Lipid Res. 2017 Jan;58(1):196-207. doi: 10.1194/jlr.M072033. Epub 2016 Nov 24.


Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients.

Abduch RH, Carolina Bueno A, Leal LF, Cavalcanti MM, Gomes DC, Brandalise SR, Masterallo MJ, Yunes JA, Martinelli CE Jr, Tone LG, Tucci S, Molina CA, Ramalho FS, Moreira AC, Cardinalli IA, Scrideli CA, Ramalho LN, de Castro M, Antonini SR.

Oncotarget. 2016 Dec 20;7(51):84634-84644. doi: 10.18632/oncotarget.12382.


Population genetics: A map of human wanderlust.

Tucci S, Akey JM.

Nature. 2016 Oct 13;538(7624):179-180. doi: 10.1038/nature19472. Epub 2016 Sep 21. No abstract available.


Intermittent urethral catheterisation: the reality of the lubricants and catheters in the clinical practice of a Brazilian service.

Mazzo A, Pecci GL, Fumincelli L, Neves RC, Dos Santos RC, Cassini MF, Tucci S Jr.

J Clin Nurs. 2016 Nov;25(21-22):3382-3390. doi: 10.1111/jocn.13466. Epub 2016 Aug 24.


Demographic History of the Genus Pan Inferred from Whole Mitochondrial Genome Reconstructions.

Lobon I, Tucci S, de Manuel M, Ghirotto S, Benazzo A, Prado-Martinez J, Lorente-Galdos B, Nam K, Dabad M, Hernandez-Rodriguez J, Comas D, Navarro A, Schierup MH, Andres AM, Barbujani G, Hvilsom C, Marques-Bonet T.

Genome Biol Evol. 2016 Jul 3;8(6):2020-30. doi: 10.1093/gbe/evw124.


The Effects of Theory of Mind Training on the False Belief Understanding of Deaf and Hard-of-Hearing Students in Prekindergarten and Kindergarten.

Tucci SL, Easterbrooks SR, Lederberg AR.

J Deaf Stud Deaf Educ. 2016 Jul;21(3):310-25. doi: 10.1093/deafed/enw031. Epub 2016 May 28.


IGF2 and IGF1R in pediatric adrenocortical tumors: roles in metastasis and steroidogenesis.

Peixoto Lira RC, Fedatto PF, Marco Antonio DS, Leal LF, Martinelli CE, de Castro M, Tucci S, Neder L, Ramalho L, Seidinger AL, Cardinalli I, Mastellaro MJ, Yunes JA, Brandalise SR, Tone LG, Rauber Antonini SR, Scrideli CA.

Endocr Relat Cancer. 2016 Jun;23(6):481-93. doi: 10.1530/ERC-15-0426. Epub 2016 May 16.


Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals.

Vernot B, Tucci S, Kelso J, Schraiber JG, Wolf AB, Gittelman RM, Dannemann M, Grote S, McCoy RC, Norton H, Scheinfeldt LB, Merriwether DA, Koki G, Friedlaender JS, Wakefield J, Pääbo S, Akey JM.

Science. 2016 Apr 8;352(6282):235-9. doi: 10.1126/science.aad9416. Epub 2016 Mar 17.


Renal response to short- and long-term exercise in very-long-chain acyl-CoA dehydrogenase-deficient (VLCAD(-/-)) mice.

Tucci S, Krogmann A, Herebian D, Spiekerkoetter U.

Mol Cell Pediatr. 2014 Dec;1(1):5. doi: 10.1186/s40348-014-0005-z. Epub 2014 Oct 2.


Evaluation of the boundary condition influence on PAH concentrations in the water column during the sediment dredging of a port.

Cutroneo L, Castellano M, Carbone C, Consani S, Gaino F, Tucci S, Magrì S, Povero P, Bertolotto RM, Canepa G, Capello M.

Mar Pollut Bull. 2015 Dec 30;101(2):583-93. doi: 10.1016/j.marpolbul.2015.10.055. Epub 2015 Oct 27.


De novo fatty acid biosynthesis and elongation in very long-chain acyl-CoA dehydrogenase-deficient mice supplemented with odd or even medium-chain fatty acids.

Tucci S, Behringer S, Spiekerkoetter U.

FEBS J. 2015 Nov;282(21):4242-53. doi: 10.1111/febs.13418. Epub 2015 Sep 11.


Medium-chain acyl-CoA dehydrogenase deficiency associated with a novel splice mutation in the ACADM gene missed by newborn screening.

Grünert SC, Wehrle A, Villavicencio-Lorini P, Lausch E, Vetter B, Schwab KO, Tucci S, Spiekerkoetter U.

BMC Med Genet. 2015 Jul 30;16:56. doi: 10.1186/s12881-015-0199-5.


Spatiotemporal Targeting of a Dual-Ligand Nanoparticle to Cancer Metastasis.

Doolittle E, Peiris PM, Doron G, Goldberg A, Tucci S, Rao S, Shah S, Sylvestre M, Govender P, Turan O, Lee Z, Schiemann WP, Karathanasis E.

ACS Nano. 2015 Aug 25;9(8):8012-21. doi: 10.1021/acsnano.5b01552. Epub 2015 Jul 28.


Sexual dimorphism of lipid metabolism in very long-chain acyl-CoA dehydrogenase deficient (VLCAD-/-) mice in response to medium-chain triglycerides (MCT).

Tucci S, Flögel U, Spiekerkoetter U.

Biochim Biophys Acta. 2015 Jul;1852(7):1442-50. doi: 10.1016/j.bbadis.2015.04.009. Epub 2015 Apr 15.


Urinary monocyte chemoattractant protein-1 levels and interstitial changes in the renal cortex and their relationship with loss of renal function in renal transplant patients with delayed graft function.

Moyses Neto M, Romão EA, Silva GE, Dantas M, Nardim ME, Tucci S Jr, Francescato HD, Coimbra TM.

Can J Kidney Health Dis. 2015 Jan 30;2:1. doi: 10.1186/s40697-015-0038-9. eCollection 2015.


Traces of medieval migrations in a socially stratified population from Northern Italy. Evidence from uniparental markers and deep-rooted pedigrees.

Boattini A, Sarno S, Pedrini P, Medoro C, Carta M, Tucci S, Ferri G, Alù M, Luiselli D, Pettener D.

Heredity (Edinb). 2015 Feb;114(2):155-62. doi: 10.1038/hdy.2014.77. Epub 2014 Sep 10.


Low expression of HLA-DRA, HLA-DPA1, and HLA-DPB1 is associated with poor prognosis in pediatric adrenocortical tumors (ACT).

Leite FA, Lira RC, Fedatto PF, Antonini SR, Martinelli CE Jr, de Castro M, Neder L, Ramalho LN, Tucci S Jr, Mastelaro MJ, Seidinger AL, Cardinalli IA, Yunes JA, Brandalise SR, Tone LG, Scrideli CA.

Pediatr Blood Cancer. 2014 Nov;61(11):1940-8. doi: 10.1002/pbc.25118. Epub 2014 Aug 23.


Urethral dysfunction due to alloxan-induced diabetes. Urodynamic and morphological evaluation.

Pegorare AB, Gonçalves MA, Suaid CA, Rodrigues Junior AA, Tucci S Jr, Suaid HJ.

Acta Cir Bras. 2014 Jul;29(7):457-64.


Cyclin D1 expression in prostate carcinoma.

Pereira RA, Ravinal RC, Costa RS, Lima MS, Tucci S, Muglia VF, Reis RB, Silva GE.

Braz J Med Biol Res. 2014 Jun;47(6):515-21. Epub 2014 May 2.


Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate.

Gomes de Souza Pegorare AB, Gonçalves MA, Martiniano de Oliveira A, Rodrigues Junior AA, Tucci S Jr, Suaid HJ.

Acta Cir Bras. 2014 Apr;29(4):274-9.


Altered expression of noncanonical Wnt pathway genes in paediatric and adult adrenocortical tumours.

Mermejo LM, Leal LF, Colli LM, Fragoso MC, Latronico AC, Tone LG, Scrideli CA, Tucci S, Martinelli CE, Yunes JA, Mastellaro MJ, Seidinger AL, Brandalise SR, Moreira AC, Ramalho LN, Antonini SR, Castro M.

Clin Endocrinol (Oxf). 2014 Oct;81(4):503-10. doi: 10.1111/cen.12462. Epub 2014 May 19.


Sonic hedgehog signaling is active in human adrenal cortex development and deregulated in adrenocortical tumors.

Gomes DC, Leal LF, Mermejo LM, Scrideli CA, Martinelli CE Jr, Fragoso MC, Latronico AC, Tone LG, Tucci S, Yunes JA, Cardinalli IA, Mastellaro MJ, Brandalise SR, Ramalho F, Moreira AC, Ramalho LN, de Castro M, Antonini SR.

J Clin Endocrinol Metab. 2014 Jul;99(7):E1209-16. doi: 10.1210/jc.2013-4098. Epub 2014 Apr 8.


Development and pathomechanisms of cardiomyopathy in very long-chain acyl-CoA dehydrogenase deficient (VLCAD(-/-)) mice.

Tucci S, Flögel U, Hermann S, Sturm M, Schäfers M, Spiekerkoetter U.

Biochim Biophys Acta. 2014 May;1842(5):677-85. doi: 10.1016/j.bbadis.2014.02.001. Epub 2014 Feb 12.


Simulations of dredged sediment spreading on a Posidonia oceanica meadow off the Ligurian coast, Northwestern Mediterranean.

Capello M, Cutroneo L, Ferranti MP, Budillon G, Bertolotto RM, Ciappa A, Cotroneo Y, Castellano M, Povero P, Tucci S.

Mar Pollut Bull. 2014 Feb 15;79(1-2):196-204. doi: 10.1016/j.marpolbul.2013.12.014. Epub 2013 Dec 23.


The prognostic value of cyclin D1 in renal cell carcinoma.

Lima MS, Pereira RA, Costa RS, Tucci S, Dantas M, Muglia VF, Ravinal RC, Barros-Silva GE.

Int Urol Nephrol. 2014 May;46(5):905-13. doi: 10.1007/s11255-013-0602-0. Epub 2013 Nov 17.


Treatment of cancer micrometastasis using a multicomponent chain-like nanoparticle.

Peiris PM, Toy R, Abramowski A, Vicente P, Tucci S, Bauer L, Mayer A, Tam M, Doolittle E, Pansky J, Tran E, Lin D, Schiemann WP, Ghaghada KB, Griswold MA, Karathanasis E.

J Control Release. 2014 Jan 10;173:51-8. doi: 10.1016/j.jconrel.2013.10.031. Epub 2013 Nov 2.


Stigmatisation of a formerly obese young female.

Tucci SA, Boyland EJ, Halford JC, Harrold JA.

Obes Facts. 2013;6(5):433-42. doi: 10.1159/000355713. Epub 2013 Oct 8.


Colostrum in menopause effects on vaginal cytology/symptoms.

Tucci S, Mancini R, De Vitis C, Noto A, Marra E, Lukic A, Giovagnoli MR, Moscarini M.

Clin Exp Obstet Gynecol. 2013;40(2):219-21.


On-command drug release from nanochains inhibits growth of breast tumors.

Peiris PM, Tam M, Vicente P, Abramowski A, Toy R, Bauer L, Mayer A, Pansky J, Doolittle E, Tucci S, Schmidt E, Shoup C, Rao S, Murray K, Gopalakrishnan R, Keri RA, Basilion JP, Griswold MA, Karathanasis E.

Pharm Res. 2014 Jun;31(6):1460-8. doi: 10.1007/s11095-013-1102-8. Epub 2013 Aug 9.


Spindle assembly checkpoint gene expression in childhood adrenocortical tumors (ACT): Overexpression of Aurora kinases A and B is associated with a poor prognosis.

Borges KS, Moreno DA, Martinelli CE Jr, Antonini SR, de Castro M, Tucci S Jr, Neder L, Ramalho LN, Seidinger AL, Cardinalli I, Mastellaro MJ, Yunes JA, Brandalise SR, Tone LG, Scrideli CA.

Pediatr Blood Cancer. 2013 Nov;60(11):1809-16. doi: 10.1002/pbc.24653. Epub 2013 Jun 20.


Fluorescence spectroscopy in renal ischemia and reperfusion: noninvasive evaluation of organ viability.

Cassini MF, da Costa MM, Bagnato VS, Tirapelli LF, Silva GE, Molina CA, Martins AC, Tucci S Jr.

Transplant Proc. 2013 Jun;45(5):1715-9. doi: 10.1016/j.transproceed.2012.10.054. Erratum in: Transplant Proc. 2014 Sep;46(7):2469.


Low nitric oxide bioavailability is associated with better responses to sildenafil in patients with erectile dysfunction.

Muniz JJ, Lacchini R, Sertório JT, Jordão AA Jr, Nobre YT, Tucci S Jr, Martins AC, Tanus-Santos JE.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Sep;386(9):805-11. doi: 10.1007/s00210-013-0882-z. Epub 2013 May 19.


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