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Reshaping Tumor Immune Microenvironment through Acidity-Responsive Nanoparticles Featured with CRISPR/Cas9-Mediated Programmed Death-Ligand 1 Attenuation and Chemotherapeutics-Induced Immunogenic Cell Death.

Tu K, Deng H, Kong L, Wang Y, Yang T, Hu Q, Hu M, Yang C, Zhang Z.

ACS Appl Mater Interfaces. 2020 Mar 30. doi: 10.1021/acsami.9b23084. [Epub ahead of print]


Tensile Properties of <111>-Oriented Nanotwinned Cu with Different Columnar Grain Structures.

Li YJ, Tu KN, Chen C.

Materials (Basel). 2020 Mar 13;13(6). pii: E1310. doi: 10.3390/ma13061310.


Tensile Properties and Thermal Stability of Unidirectionally <111>-Oriented Nanotwinned and <110>-Oriented Microtwinned Copper.

Li YJ, Tu KN, Chen C.

Materials (Basel). 2020 Mar 8;13(5). pii: E1211. doi: 10.3390/ma13051211.


Linking Parental Monitoring and Psychological Control with Internalizing Symptoms in Early Adolescence: The Moderating Role of Vagal Tone.

Cai T, Tu KM.

J Abnorm Child Psychol. 2020 Mar 13. doi: 10.1007/s10802-020-00631-w. [Epub ahead of print]


Improving Tumor Hypoxia and Radiotherapy Resistance via in situ Nitric Oxide Release Strategy.

Tu J, Tu K, Xu H, Wang L, Yuan X, Qin X, Kong L, Chu Q, Zhang Z.

Eur J Pharm Biopharm. 2020 Mar 6. pii: S0939-6411(20)30059-X. doi: 10.1016/j.ejpb.2020.03.003. [Epub ahead of print]


Assessment of an Algorithm for Prescription of Oral Anticoagulation for Patients With Atrial Fibrillation in Emergency Departments.

Atzema CL, Fang J, Cox JL, Chong AS, Tu K, Austin PC.

JAMA Netw Open. 2020 Mar 2;3(3):e200306. doi: 10.1001/jamanetworkopen.2020.0306. No abstract available.


Cdk5 knocking out mediated by CRISPR-Cas9 genome editing for PD-L1 attenuation and enhanced antitumor immunity.

Deng H, Tan S, Gao X, Zou C, Xu C, Tu K, Song Q, Fan F, Huang W, Zhang Z.

Acta Pharm Sin B. 2020 Feb;10(2):358-373. doi: 10.1016/j.apsb.2019.07.004. Epub 2019 Jul 23.


Identifying and characterizing psoriasis and psoriatic arthritis patients in Ontario administrative data: a population-based study from 1991 to 2015.

Eder L, Widdifield J, Rosen CF, Alhusayen R, Cheng SY, Young J, Campbell W, Bernatsky S, Gladman DD, Paterson M, Tu K.

J Rheumatol. 2020 Feb 15. pii: jrheum.190659. doi: 10.3899/jrheum.190659. [Epub ahead of print]


Cerebral palsy in Canada, 2011-2031: results of a microsimulation modelling study of epidemiological and cost impacts.

Amankwah N, Oskoui M, Garner R, Bancej C, Manuel DG, Wall R, Finès P, Bernier J, Tu K, Reimer K.

Health Promot Chronic Dis Prev Can. 2020 Feb;40(2):25-37. doi: 10.24095/hpcdp.40.2.01. English, French.


Focal Adhesion Kinase Promotes Hepatic Stellate Cell Activation by Regulating Plasma Membrane Localization of TGFβ Receptor 2.

Chen Y, Li Q, Tu K, Wang Y, Wang X, Liu D, Chen C, Liu D, Yang R, Qiu W, Kang N.

Hepatol Commun. 2019 Dec 20;4(2):268-283. doi: 10.1002/hep4.1452. eCollection 2020 Feb.


LncRNA RUNX1-IT1 which is downregulated by hypoxia-driven histone deacetylase 3 represses proliferation and cancer stem-like properties in hepatocellular carcinoma cells.

Sun L, Wang L, Chen T, Shi Y, Yao B, Liu Z, Wang Y, Li Q, Liu R, Niu Y, Tu K, Liu Q.

Cell Death Dis. 2020 Feb 5;11(2):95. doi: 10.1038/s41419-020-2274-x.


Risk of Mortality in Immigrants with Multiple Sclerosis in Ontario, Canada.

Rotstein D, Maxwell C, Tu K, Schultz SE, Fung K, Marrie RA.

Neuroepidemiology. 2020;54(2):148-156. doi: 10.1159/000506161. Epub 2020 Feb 5.


Evaluation of structural and physicochemical properties of octenyl succinic anhydride modified sweet potato starch with different degrees of substitution.

Guo J, Tang W, Quek SY, Liu Z, Lu S, Tu K.

J Food Sci. 2020 Mar;85(3):666-672. doi: 10.1111/1750-3841.15031. Epub 2020 Jan 30.


Serious infections in patients with myasthenia gravis: population-based cohort study.

Kassardjian CD, Widdifield J, Paterson JM, Kopp A, Nagamuthu C, Barnett C, Tu K, Breiner A.

Eur J Neurol. 2020 Apr;27(4):702-708. doi: 10.1111/ene.14153. Epub 2020 Feb 17.


Isometric exercise facilitates attention to salient events in women via the noradrenergic system.

Mather M, Huang R, Clewett D, Nielsen SE, Velasco R, Tu K, Han S, Kennedy BL.

Neuroimage. 2020 Apr 15;210:116560. doi: 10.1016/j.neuroimage.2020.116560. Epub 2020 Jan 21.


Health Care Utilization for Musculoskeletal Issues During the Pre-diagnosis Period in Psoriatic Arthritis - A Population-Based Study.

Eder L, Tu K, Rosen CF, Alhusayen R, Cheng SY, Young J, Campbell W, Bernatsky S, Gladman DD, Paterson JM, Widdifield J.

Arthritis Care Res (Hoboken). 2020 Jan 21. doi: 10.1002/acr.24146. [Epub ahead of print]


The novel platinum(IV) prodrug with self-assembly property and structure-transformable character against triple-negative breast cancer.

Yang C, Tu K, Gao H, Zhang L, Sun Y, Yang T, Kong L, Ouyang D, Zhang Z.

Biomaterials. 2020 Feb;232:119751. doi: 10.1016/j.biomaterials.2019.119751. Epub 2019 Dec 31.


Proteomics analysis reveals the interleukin-35-dependent regulatory mechanisms affecting CD8+ T-cell functions.

Li X, Dong Y, Tu K, Wang W.

Cell Immunol. 2020 Feb;348:104022. doi: 10.1016/j.cellimm.2019.104022. Epub 2019 Nov 26.


Preferences for a self-management e-health tool for patients with chronic kidney disease: results of a patient-oriented consensus workshop.

Donald M, Beanlands H, Straus S, Ronksley P, Tam-Tham H, Finlay J, Smekal M, Elliott MJ, Farragher J, Herrington G, Harwood L, Large CA, Large CL, Waldvogel B, Delgado ML, Sparkes D, Tong A, Grill A, Novak M, James MT, Brimble KS, Samuel S, Tu K, Hemmelgarn BR.

CMAJ Open. 2019 Dec 10;7(4):E713-E720. doi: 10.9778/cmajo.20190081. Print 2019 Oct-Dec.


Ionic Polyimide Derived Porous Carbon Nanosheets as High-Efficiency Oxygen Reduction Catalysts for Zn-Air Batteries.

Tu K, Zou L, Yang C, Su Y, Lu C, Zhu J, Zhang F, Ke C, Zhuang X.

Chemistry. 2019 Dec 1. doi: 10.1002/chem.201904769. [Epub ahead of print]


Cardiac autonomic functioning and post-traumatic stress: A preliminary study in youth at-risk for PTSD.

Cohen JR, Thomsen KN, Tu KM, Thakur H, McNeil S, Menon SV.

Psychiatry Res. 2020 Feb;284:112684. doi: 10.1016/j.psychres.2019.112684. Epub 2019 Nov 7.


Hot air and UV-C treatments promote anthocyanin accumulation in peach fruit through their regulations of sugars and organic acids.

Zhou D, Li R, Zhang H, Chen S, Tu K.

Food Chem. 2020 Mar 30;309:125726. doi: 10.1016/j.foodchem.2019.125726. Epub 2019 Oct 21.


MS risk in immigrants in the McDonald era: A population-based study in Ontario, Canada.

Rotstein DL, Marrie RA, Maxwell C, Gandhi S, Schultz SE, Fung K, Tu K.

Neurology. 2019 Dec 10;93(24):e2203-e2215. doi: 10.1212/WNL.0000000000008611. Epub 2019 Nov 5.


Self-assembled N-doped carbon with a tube-in-tube nanostructure for lithium-sulfur batteries.

Zhu X, Li Y, Li R, Tu K, Li J, Xie Z, Lei J, Liu D, Qu D.

J Colloid Interface Sci. 2020 Feb 1;559:244-253. doi: 10.1016/j.jcis.2019.10.027. Epub 2019 Oct 9.


Element Effects on High-Entropy Alloy Vacancy and Heterogeneous Lattice Distortion Subjected to Quasi-equilibrium Heating.

Huang EW, Chou HS, Tu KN, Hung WS, Lam TN, Tsai CW, Chiang CY, Lin BH, Yeh AC, Chang SH, Chang YJ, Yang JJ, Li XY, Ku CS, An K, Chang YW, Jao YL.

Sci Rep. 2019 Oct 15;9(1):14788. doi: 10.1038/s41598-019-51297-4.


Effect on Treatment Adherence of Distributing Essential Medicines at No Charge: The CLEAN Meds Randomized Clinical Trial.

Persaud N, Bedard M, Boozary AS, Glazier RH, Gomes T, Hwang SW, Jüni P, Law MR, Mamdani MM, Manns BJ, Martin D, Morgan SG, Oh PI, Pinto AD, Shah BR, Sullivan F, Umali N, Thorpe KE, Tu K, Laupacis A; Carefully Selected and Easily Accessible at No Charge Medicines (CLEAN Meds) Study Team.

JAMA Intern Med. 2019 Oct 7. doi: 10.1001/jamainternmed.2019.4472. [Epub ahead of print]


MicroRNA-769-5p contributes to the proliferation, migration and invasion of hepatocellular carcinoma cells by attenuating RYBP.

Xian Y, Wang L, Yao B, Yang W, Mo H, Zhang L, Tu K.

Biomed Pharmacother. 2019 Oct;118:109343. doi: 10.1016/j.biopha.2019.109343. Epub 2019 Aug 13.


Semiconducting SN2 monolayer with three-dimensional auxetic properties: a global minimum with tetracoordinated sulfurs.

Li F, Lv X, Gu J, Tu K, Gong J, Jin P, Chen Z.

Nanoscale. 2020 Jan 7;12(1):85-92. doi: 10.1039/c9nr07263b. Epub 2019 Sep 18.


Improving the anti-fouling property and permeate flux of hollow fiber composite nanofiltration membrane using β-cyclodextrin.

He Y, Miao J, Jiang Z, Tu K, Yang H, Chen S, Zhang L, Zhang R.

Sci Rep. 2019 Aug 27;9(1):12435. doi: 10.1038/s41598-019-48908-5.


Ambient Air Pollution and the Risk of Atrial Fibrillation and Stroke: A Population-Based Cohort Study.

Shin S, Burnett RT, Kwong JC, Hystad P, van Donkelaar A, Brook JR, Goldberg MS, Tu K, Copes R, Martin RV, Liu Y, Kopp A, Chen H.

Environ Health Perspect. 2019 Aug;127(8):87009. doi: 10.1289/EHP4883. Epub 2019 Aug 26.


Verticillin A suppresses HGF-induced migration and invasion via repression of the c-Met/FAK/Src pathway in human gastric and cervical cancer cells.

Lu J, Li X, Tu K, Guan Y, Fung KP, Liu F.

Onco Targets Ther. 2019 Jul 26;12:5823-5833. doi: 10.2147/OTT.S208683. eCollection 2019.


Content and Quality of Websites for Patients With Chronic Kidney Disease: An Environmental Scan.

Smekal M, Gil S, Donald M, Beanlands H, Straus S, Herrington G, Sparkes D, Harwood L, Tong A, Grill A, Tu K, Waldvogel B, Large C, Large C, Novak M, James M, Elliott M, Delgado M, Brimble S, Samuel S, Hemmelgarn BR.

Can J Kidney Health Dis. 2019 Jul 30;6:2054358119863091. doi: 10.1177/2054358119863091. eCollection 2019.


The role of cardiovascular disease in the relationship between air pollution and incident dementia: a population-based cohort study.

Ilango SD, Chen H, Hystad P, van Donkelaar A, Kwong JC, Tu K, Martin RV, Benmarhnia T.

Int J Epidemiol. 2019 Jul 25. pii: dyz154. doi: 10.1093/ije/dyz154. [Epub ahead of print]


miR-1204 promotes hepatocellular carcinoma progression through activating MAPK and c-Jun/AP1 signaling by targeting ZNF418.

Wang L, Sun L, Wang Y, Yao B, Liu R, Chen T, Tu K, Liu Q, Liu Z.

Int J Biol Sci. 2019 Jun 2;15(7):1514-1522. doi: 10.7150/ijbs.33658. eCollection 2019.


The Open Chromatin Landscape of Non-Small Cell Lung Carcinoma.

Wang Z, Tu K, Xia L, Luo K, Luo W, Tang J, Lu K, Hu X, He Y, Qiao W, Zhou Y, Zhang J, Cao F, Dai S, Tian P, Wang Y, Liu L, Che G, Zhou Q, Xie D, Li W.

Cancer Res. 2019 Oct 1;79(19):4840-4854. doi: 10.1158/0008-5472.CAN-18-3663. Epub 2019 Jun 17.


Grading and Sorting of Grape Berries Using Visible-Near Infrared Spectroscopy on the Basis of Multiple Inner Quality Parameters.

Xiao H, Feng L, Song D, Tu K, Peng J, Pan L.

Sensors (Basel). 2019 Jun 7;19(11). pii: E2600. doi: 10.3390/s19112600.


Quality and continuity of information between primary care physicians and rheumatologists.

Wong J, Tu K, Bernatsky S, Jaakkimainen L, Thorne JC, Ahluwalia V, Paterson JM, Widdifield J.

BMC Rheumatol. 2019 May 24;3:1. doi: 10.1186/s41927-019-0067-6. eCollection 2019. Erratum in: BMC Rheumatol. 2019 Aug 20;3:35.


High anti-neutrophil cytoplasmic antibody titers are associated with the requirement of permanent dialysis in patients with myeloperoxidase-ANCA-associated vasculitis.

Yen CL, Tian YC, Wu HH, Tu KH, Liu SH, Lee CC, Fang JT, Yang CW, Li YJ.

J Formos Med Assoc. 2019 Oct;118(10):1408-1415. doi: 10.1016/j.jfma.2019.05.004. Epub 2019 May 24.


Tunable Wood by Reversible Interlocking and Bioinspired Mechanical Gradients.

Frey M, Biffi G, Adobes-Vidal M, Zirkelbach M, Wang Y, Tu K, Hirt AM, Masania K, Burgert I, Keplinger T.

Adv Sci (Weinh). 2019 Mar 28;6(10):1802190. doi: 10.1002/advs.201802190. eCollection 2019 May 17.


Temporal trends in severe obesity prevalence in children and youth from primary care electronic medical records in Ontario: a repeated cross-sectional study.

Carsley S, Pope EI, Anderson LN, Tremblay MS, Tu K, Birken CS; Team to Address Bariatric Care in Canadian Children.

CMAJ Open. 2019 May 19;7(2):E351-E359. doi: 10.9778/cmajo.20180174. Print 2019 Apr-Jun.


Restoring fresh texture in cooked aged rice with reducing agents.

Diao M, Guo Y, Tian W, Tu K, Guan L, Wei M.

Food Res Int. 2019 Jul;121:84-90. doi: 10.1016/j.foodres.2019.03.023. Epub 2019 Mar 12.


Genomic analysis of benign prostatic hyperplasia implicates cellular re-landscaping in disease pathogenesis.

Middleton LW, Shen Z, Varma S, Pollack AS, Gong X, Zhu S, Zhu C, Foley JW, Vennam S, Sweeney RT, Tu K, Biscocho J, Eminaga O, Nolley R, Tibshirani R, Brooks JD, West RB, Pollack JR.

JCI Insight. 2019 May 16;5. pii: 129749. doi: 10.1172/jci.insight.129749.


Prognostic value of endothelial biomarkers in refractory cardiogenic shock with ECLS: a prospective monocentric study.

Tsai TY, Tu KH, Tsai FC, Nan YY, Fan PC, Chang CH, Tian YC, Fang JT, Yang CW, Chen YC.

BMC Anesthesiol. 2019 May 15;19(1):73. doi: 10.1186/s12871-019-0747-1.


Long non-coding RNA AGAP2-AS1, functioning as a competitive endogenous RNA, upregulates ANXA11 expression by sponging miR-16-5p and promotes proliferation and metastasis in hepatocellular carcinoma.

Liu Z, Wang Y, Wang L, Yao B, Sun L, Liu R, Chen T, Niu Y, Tu K, Liu Q.

J Exp Clin Cancer Res. 2019 May 14;38(1):194. doi: 10.1186/s13046-019-1188-x.


The "Heart" of depression during early adolescence.

Tu KM, Li X, Cohen JR.

Dev Psychobiol. 2019 Dec;61(8):1168-1179. doi: 10.1002/dev.21862. Epub 2019 May 12.


Postharvest hot air and UV-C treatments enhance aroma-related volatiles by simulating the lipoxygenase pathway in peaches during cold storage.

Zhou D, Sun Y, Li M, Zhu T, Tu K.

Food Chem. 2019 Sep 15;292:294-303. doi: 10.1016/j.foodchem.2019.04.049. Epub 2019 Apr 12.


Evidence to support common application switching behaviour on smartphones.

Turner LD, Whitaker RM, Allen SM, Linden DEJ, Tu K, Li J, Towsley D.

R Soc Open Sci. 2019 Mar 20;6(3):190018. doi: 10.1098/rsos.190018. eCollection 2019 Mar.


Reliability of routinely collected anthropometric measurements in primary care.

Carsley S, Parkin PC, Tu K, Pullenayegum E, Persaud N, Maguire JL, Birken CS; TARGet Kids! Collaboration.

BMC Med Res Methodol. 2019 Apr 24;19(1):84. doi: 10.1186/s12874-019-0726-8.


p300 Acetyltransferase Is a Cytoplasm-to-Nucleus Shuttle for SMAD2/3 and TAZ Nuclear Transport in Transforming Growth Factor β-Stimulated Hepatic Stellate Cells.

Wang Y, Tu K, Liu D, Guo L, Chen Y, Li Q, Maiers JL, Liu Z, Shah VH, Dou C, Tschumperlin D, Voneschen L, Yang R, Kang N.

Hepatology. 2019 Oct;70(4):1409-1423. doi: 10.1002/hep.30668. Epub 2019 May 23.


Predictors and variability of antibiotic prescribing amongst family physicians.

Schwartz KL, Brown KA, Etches J, Langford BJ, Daneman N, Tu K, Johnstone J, Achonu C, Garber G.

J Antimicrob Chemother. 2019 Jul 1;74(7):2098-2105. doi: 10.1093/jac/dkz112.


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