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Rural-Urban Differences in Stroke Risk Factors, Incidence, and Mortality in People With and Without Prior Stroke.

Kapral MK, Austin PC, Jeyakumar G, Hall R, Chu A, Khan AM, Jin AY, Martin C, Manuel D, Silver FL, Swartz RH, Tu JV.

Circ Cardiovasc Qual Outcomes. 2019 Feb;12(2):e004973. doi: 10.1161/CIRCOUTCOMES.118.004973.


The Risk of Heart Failure and Other Cardiovascular Hospitalizations After Early Stage Breast Cancer: A Matched Cohort Study.

Abdel-Qadir H, Thavendiranathan P, Austin PC, Lee DS, Amir E, Tu JV, Fung K, Anderson GM.

J Natl Cancer Inst. 2019 Jan 31. doi: 10.1093/jnci/djy218. [Epub ahead of print]


Unexpected High Prevalence of Cardiovascular Disease Risk Factors and Psychiatric Disease Among Young People With Sudden Cardiac Arrest.

Allan KS, Morrison LJ, Pinter A, Tu JV, Dorian P; Rescu Investigators.

J Am Heart Assoc. 2019 Jan 22;8(2):e010330. doi: 10.1161/JAHA.118.010330.


Association between transitional care factors and hospital readmission after transcatheter aortic valve replacement: a retrospective observational cohort study.

Czarnecki A, Austin PC, Fremes SE, Tu JV, Wijeysundera HC, Ko DT.

BMC Cardiovasc Disord. 2019 Jan 18;19(1):23. doi: 10.1186/s12872-019-1003-9.


Prospective Validation of the Emergency Heart Failure Mortality Risk Grad for Acute Heart Failure: The Acute Congestive Heart Failure Urgent Care Evaluation (ACUTE) Study.

Lee DS, Lee JS, Schull MJ, Borgundvaag B, Edmonds ML, Ivankovic M, McLeod SL, Dreyer JF, Sabbah S, Levy PD, O'Neill T, Chong A, Stukel TA, Austin PC, Tu JV.

Circulation. 2018 Nov 29. doi: 10.1161/CIRCULATIONAHA.118.035509. [Epub ahead of print]


Eligibility, Clinical Outcomes, and Budget Impact of PCSK9 Inhibitor Adoption: The CANHEART PCSK9 Study.

Ko DT, Khan AM, Kotrri G, Austin PC, Wijeysundera HC, Koh M, Chu A, Jackevicius CA, Lawler PR, Tu JV.

J Am Heart Assoc. 2018 Nov 6;7(21):e010007. doi: 10.1161/JAHA.118.010007.


Risk factors for cardiovascular disease in heterozygous familial hypercholesterolemia: A systematic review and meta-analysis.

Akioyamen LE, Genest J, Chu A, Inibhunu H, Ko DT, Tu JV.

J Clin Lipidol. 2019 Jan - Feb;13(1):15-30. doi: 10.1016/j.jacl.2018.10.012. Epub 2018 Nov 7.


A Clinical Risk Scoring Tool to Predict Readmission After Cardiac Surgery: An Ontario Administrative and Clinical Population Database Study.

Tam DY, Fang J, Tran A, Tu JV, Ko DT, Deb S, Fremes SE.

Can J Cardiol. 2018 Dec;34(12):1655-1664. doi: 10.1016/j.cjca.2018.09.004. Epub 2018 Sep 22.


Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Update 2018.

Brunham LR, Ruel I, Aljenedil S, Rivière JB, Baass A, Tu JV, Mancini GBJ, Raggi P, Gupta M, Couture P, Pearson GJ, Bergeron J, Francis GA, McCrindle BW, Morrison K, St-Pierre J, Henderson M, Hegele RA, Genest J, Goguen J, Gaudet D, Paré G, Romney J, Ransom T, Bernard S, Katz P, Joy TR, Bewick D, Brophy J.

Can J Cardiol. 2018 Dec;34(12):1553-1563. doi: 10.1016/j.cjca.2018.09.005.


Disability-free survival after coronary artery bypass grafting in women and men with heart failure.

Sun LY, Tu JV, Lee DS, Beanlands RS, Ruel M, Austin PC, Eddeen AB, Liu PP.

Open Heart. 2018 Nov 5;5(2):e000911. doi: 10.1136/openhrt-2018-000911. eCollection 2018.


Multiple Arterial Grafting Is Associated With Better Outcomes for Coronary Artery Bypass Grafting Patients.

Rocha RV, Tam DY, Karkhanis R, Nedadur R, Fang J, Tu JV, Gaudino M, Royse A, Fremes SE.

Circulation. 2018 Nov 6;138(19):2081-2090. doi: 10.1161/CIRCULATIONAHA.118.034464.


Factors associated with door-in to door-out delays among ST-segment elevation myocardial infarction (STEMI) patients transferred for primary percutaneous coronary intervention: a population-based cohort study in Ontario, Canada.

Shi O, Khan AM, Rezai MR, Jackevicius CA, Cox J, Atzema CL, Ko DT, Stukel TA, Lambert LJ, Natarajan MK, Zheng ZJ, Tu JV.

BMC Cardiovasc Disord. 2018 Oct 29;18(1):204. doi: 10.1186/s12872-018-0940-z.


Statins Reduce Abdominal Aortic Aneurysm Growth, Rupture, and Perioperative Mortality: A Systematic Review and Meta-Analysis.

Salata K, Syed M, Hussain MA, de Mestral C, Greco E, Mamdani M, Tu JV, Forbes TL, Bhatt DL, Verma S, Al-Omran M.

J Am Heart Assoc. 2018 Oct 2;7(19):e008657. doi: 10.1161/JAHA.118.008657.


Association Between Statin Use and Cardiovascular Events After Carotid Artery Revascularization.

Hussain MA, Saposnik G, Raju S, Salata K, Mamdani M, Tu JV, Bhatt DL, Verma S, Al-Omran M.

J Am Heart Assoc. 2018 Aug 21;7(16):e009745. doi: 10.1161/JAHA.118.009745.


Emergency Department Volume and Outcomes for Patients After Chest Pain Assessment.

Ko DT, Dattani ND, Austin PC, Schull MJ, Ross JS, Wijeysundera HC, Tu JV, Eberg M, Koh M, Krumholz HM.

Circ Cardiovasc Qual Outcomes. 2018 Nov;11(11):e004683. doi: 10.1161/CIRCOUTCOMES.118.004683.


Validation of abdominal aortic aneurysm repair codes in Ontario administrative data.

Salata K, Hussain MA, De Mestral C, Greco E, Mamdani M, Tu JV, Forbes TL, Verma S, Al-Omran M.

Clin Invest Med. 2018 Sep 30;41(3):E148-E155. doi: 10.25011/cim.v41i3.30858.


Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2018 update.

Tobe SW, Stone JA, Anderson T, Bacon S, Cheng AYY, Daskalopoulou SS, Ezekowitz JA, Gregoire JC, Gubitz G, Jain R, Keshavjee K, Lindsay P, L'Abbe M, Lau DCW, Leiter LA, O'Meara E, Pearson GJ, Rabi DM, Sherifali D, Selby P, Tu JV, Wharton S, Walker KM, Hua-Stewart D, Liu PP.

CMAJ. 2018 Oct 9;190(40):E1192-E1206. doi: 10.1503/cmaj.180194. No abstract available.


Sex-Specific Trends in Incidence and Mortality for Urban and Rural Ambulatory Patients with Heart Failure in Eastern Ontario from 1994 to 2013.

Sun LY, Tu JV, Sherrard H, Rodger N, Coutinho T, Turek M, Chan E, Tulloch H, McDonnell L, Mielniczuk LM.

J Card Fail. 2018 Sep;24(9):568-574. doi: 10.1016/j.cardfail.2018.07.465. Epub 2018 Aug 10.


Simplified Canadian Definition for Familial Hypercholesterolemia.

Ruel I, Brisson D, Aljenedil S, Awan Z, Baass A, Bélanger A, Bergeron J, Bewick D, Brophy JM, Brunham LR, Couture P, Dufour R, Francis GA, Frohlich J, Gagné C, Gaudet D, Grégoire JC, Gupta M, Hegele RA, Mancini GBJ, McCrindle BW, Pang J, Raggi P, Tu JV, Watts GF, Genest J.

Can J Cardiol. 2018 Sep;34(9):1210-1214. doi: 10.1016/j.cjca.2018.05.015. Epub 2018 May 19.


A clinical decision instrument to predict 30-day death and cardiovascular hospitalizations after an emergency department visit for atrial fibrillation: The Atrial Fibrillation in the Emergency Room, Part 2 (AFTER2) study.

Atzema CL, Dorian P, Fang J, Tu JV, Lee DS, Chong AS, Austin PC.

Am Heart J. 2018 Sep;203:85-92. doi: 10.1016/j.ahj.2018.06.005. Epub 2018 Jun 12.


Development and validation of a cardiovascular disease risk-prediction model using population health surveys: the Cardiovascular Disease Population Risk Tool (CVDPoRT).

Manuel DG, Tuna M, Bennett C, Hennessy D, Rosella L, Sanmartin C, Tu JV, Perez R, Fisher S, Taljaard M.

CMAJ. 2018 Jul 23;190(29):E871-E882. doi: 10.1503/cmaj.170914.


Association of Frailty and Long-Term Survival in Patients Undergoing Coronary Artery Bypass Grafting.

Tran DTT, Tu JV, Dupuis JY, Bader Eddeen A, Sun LY.

J Am Heart Assoc. 2018 Jul 20;7(15). pii: e009882. doi: 10.1161/JAHA.118.009882.


Sex differences in outcomes of heart failure in an ambulatory, population-based cohort from 2009 to 2013.

Sun LY, Tu JV, Coutinho T, Turek M, Rubens FD, McDonnell L, Tulloch H, Eddeen AB, Mielniczuk LM.

CMAJ. 2018 Jul 16;190(28):E848-E854. doi: 10.1503/cmaj.180177.


Importance of Considering Competing Risks in Time-to-Event Analyses: Application to Stroke Risk in a Retrospective Cohort Study of Elderly Patients With Atrial Fibrillation.

Abdel-Qadir H, Fang J, Lee DS, Tu JV, Amir E, Austin PC, Anderson GM.

Circ Cardiovasc Qual Outcomes. 2018 Jul;11(7):e004580. doi: 10.1161/CIRCOUTCOMES.118.004580.


Prevalence and Long-Term Survival After Coronary Artery Bypass Grafting in Women and Men With Heart Failure and Preserved Versus Reduced Ejection Fraction.

Sun LY, Tu JV, Bader Eddeen A, Liu PP.

J Am Heart Assoc. 2018 Jun 16;7(12). pii: e008902. doi: 10.1161/JAHA.118.008902.


Anxiety, depression, and health-related quality of life in heterozygous familial hypercholesterolemia: A systematic review and meta-analysis.

Akioyamen LE, Genest J, Shan SD, Inibhunu H, Chu A, Tu JV.

J Psychosom Res. 2018 Jun;109:32-43. doi: 10.1016/j.jpsychores.2018.03.170. Epub 2018 Mar 27.


Trends in the incidence and outcomes of patients with aortic stenosis hospitalization.

Czarnecki A, Qiu F, Koh M, Alter DA, Austin PC, Fremes SE, Tu JV, Wijeysundera HC, Yan AT, Ko DT.

Am Heart J. 2018 May;199:144-149. doi: 10.1016/j.ahj.2018.02.010. Epub 2018 Feb 13.


Projected Real-World Effectiveness of Using Aggressive Low-Density Lipoprotein Cholesterol Targets Among Elderly Statin Users Following Acute Coronary Syndromes in Canada.

Alter DA, Tu JV, Koh M, Jackevicius CA, Austin PC, Rezai MR, Bhatia RS, Johnston S, Udell JA, Ko DT.

J Am Heart Assoc. 2018 May 12;7(10). pii: e007535. doi: 10.1161/JAHA.117.007535.


Canadian Alliance for Healthy Hearts and Minds: First Nations Cohort Study Rationale and Design.

Anand SS, Abonyi S, Arbour L, Brook J, Bruce S, Castleden H, Desai D, de Souza RJ, Harris S, Irvine J, Lai C, Lewis D, Oster RT, Poirier P, Toth EL, Bannon K, Chrisjohn V, Davis AD, L'Hommecourt J, Littlechild R, McMullin K, McIntosh S, Morrison J, Picard M, Landing First Nation P, M Thomas M, Tusevljak N, Friedrich MG, Tu JV.

Prog Community Health Partnersh. 2018;12(1):55-64. doi: 10.1353/cpr.2018.0006.


Clinical Outcomes of Plavix and Generic Clopidogrel for Patients Hospitalized With an Acute Coronary Syndrome.

Ko DT, Krumholz HM, Tu JV, Austin PC, Stukel TA, Koh M, Chong A, de Melo JF Jr, Jackevicius CA.

Circ Cardiovasc Qual Outcomes. 2018 Mar;11(3):e004194. doi: 10.1161/CIRCOUTCOMES.117.004194.


Effect of Electrophysiology Assessment on Mortality and Hospitalizations in Patients With New-Onset Atrial Fibrillation.

Singh SM, Webster L, Qiu F, Austin PC, Ko DT, Tu JV, Wijeysundera HC.

Am J Cardiol. 2018 Apr 1;121(7):830-835. doi: 10.1016/j.amjcard.2017.12.031. Epub 2018 Jan 9.


Risk of intracranial hemorrhage after carotid artery stenting versus endarterectomy: a population-based study.

Hussain MA, Alali AS, Mamdani M, Tu JV, Saposnik G, Salata K, Nathens AB, de Mestral C, Bhatt DL, Verma S, Al-Omran M.

J Neurosurg. 2018 Dec 1;129(6):1522-1529. doi: 10.3171/2017.8.JNS171142.


Association of high-density lipoprotein cholesterol with non-fatal cardiac and non-cardiac events: a CANHEART substudy.

Wijeysundera HC, Koh M, Alter DA, Austin PC, Jackevicius CA, Tu JV, Ko DT.

Open Heart. 2017 Dec 17;4(2):e000731. doi: 10.1136/openhrt-2017-000731. eCollection 2017.


Recurrent events analysis for examination of hospitalizations in heart failure: insights from the Enhanced Feedback for Effective Cardiac Treatment (EFFECT) trial.

Braga JR, Tu JV, Austin PC, Sutradhar R, Ross HJ, Lee DS.

Eur Heart J Qual Care Clin Outcomes. 2018 Jan 1;4(1):18-26. doi: 10.1093/ehjqcco/qcx015.


The Relationship Between Cardiologist Care and Clinical Outcomes in Patients With New-Onset Atrial Fibrillation.

Singh SM, Qiu F, Webster L, Austin PC, Ko DT, Tu JV, Wijeysundera HC.

Can J Cardiol. 2017 Dec;33(12):1693-1700. doi: 10.1016/j.cjca.2017.10.003.


Estimating the prevalence of heterozygous familial hypercholesterolaemia: a systematic review and meta-analysis.

Akioyamen LE, Genest J, Shan SD, Reel RL, Albaum JM, Chu A, Tu JV.

BMJ Open. 2017 Sep 1;7(9):e016461. doi: 10.1136/bmjopen-2017-016461. Review.


Association between operator specialty and outcomes after carotid artery revascularization.

Hussain MA, Mamdani M, Tu JV, Saposnik G, Salata K, Bhatt DL, Verma S, Al-Omran M.

J Vasc Surg. 2018 Feb;67(2):478-489.e6. doi: 10.1016/j.jvs.2017.05.123. Epub 2017 Aug 18.


Interventions Supporting Long-term Adherence aNd Decreasing cardiovascular events (ISLAND): Pragmatic randomized trial protocol.

Ivers N, Schwalm JD, Witteman HO, Presseau J, Taljaard M, McCready T, Bosiak B, Cunningham J, Smarz S, Desveaux L, Tu JV, Atzema C, Oakes G, Isaranuwatchai W, Grace SL, Bhatia RS, Natarajan M, Grimshaw JM.

Am Heart J. 2017 Aug;190:64-75. doi: 10.1016/j.ahj.2017.05.007. Epub 2017 May 21.


Comparison of Anatomic and Clinical Outcomes in Patients Undergoing Alternative Initial Noninvasive Testing Strategies for the Diagnosis of Stable Coronary Artery Disease.

Roifman I, Wijeysundera HC, Austin PC, Rezai MR, Wright GA, Tu JV.

J Am Heart Assoc. 2017 Jul 19;6(7). pii: e005462. doi: 10.1161/JAHA.116.005462.


Electrocardiograms in Low-Risk Patients Undergoing an Annual Health Examination.

Bhatia RS, Bouck Z, Ivers NM, Mecredy G, Singh J, Pendrith C, Ko DT, Martin D, Wijeysundera HC, Tu JV, Wilson L, Wintemute K, Dorian P, Tepper J, Austin PC, Glazier RH, Levinson W.

JAMA Intern Med. 2017 Sep 1;177(9):1326-1333. doi: 10.1001/jamainternmed.2017.2649.


Response to: "A comprehensive approach needed to address regional variation".

Tu JV.

CMAJ. 2017 Jun 19;189(24):E841. doi: 10.1503/cmaj.733086. No abstract available.


"Presumed cardiac" arrest in children and young adults: A misnomer?

Allan KS, Morrison LJ, Pinter A, Tu JV, Dorian P; Rescu Epistry Investigators.

Resuscitation. 2017 Aug;117:73-79. doi: 10.1016/j.resuscitation.2017.06.003. Epub 2017 Jun 7.


Reply: Proinflammatory State, Diverse Protective Plasma Proteins Including High-Density Lipoprotein Particles, and Outcome.

Ko DT, Tu JV.

J Am Coll Cardiol. 2017 May 30;69(21):2676-2677. doi: 10.1016/j.jacc.2017.03.576. No abstract available.


Long-term Outcomes of Carotid Endarterectomy Versus Stenting in a Multicenter Population-based Canadian Study.

Hussain MA, Mamdani M, Tu JV, Saposnik G, Aljabri B, Bhatt DL, Verma S, Al-Omran M.

Ann Surg. 2018 Aug;268(2):364-373. doi: 10.1097/SLA.0000000000002301.


The Cardiovascular Health in Ambulatory Care Research Team performance indicators for the primary prevention of cardiovascular disease: a modified Delphi panel study.

Tu JV, Maclagan LC, Ko DT, Atzema CL, Booth GL, Johnston S, Tu K, Lee DS, Bierman A, Hall R, Bhatia RS, Gershon AS, Tobe SW, Sanmartin C, Liu P, Chu A; CANHEART Primary Prevention Indicator Expert Panel.

CMAJ Open. 2017 Apr 25;5(2):E315-E321. doi: 10.9778/cmajo.20160139.


Regional variations in ambulatory care and incidence of cardiovascular events.

Tu JV, Chu A, Maclagan L, Austin PC, Johnston S, Ko DT, Cheung I, Atzema CL, Booth GL, Bhatia RS, Lee DS, Jackevicius CA, Kapral MK, Tu K, Wijeysundera HC, Alter DA, Udell JA, Manuel DG, Mondal P, Hogg W; Cardiovascular Health in Ambulatory Care Research Team (CANHEART).

CMAJ. 2017 Apr 3;189(13):E494-E501. doi: 10.1503/cmaj.160823.


Reply: HDL-C and Mortality.

Ko DT, Tu JV.

J Am Coll Cardiol. 2017 Apr 4;69(13):1759-1760. doi: 10.1016/j.jacc.2017.01.039. No abstract available.


Association Between Cardiovascular Risk Factors and Aortic Stenosis: The CANHEART Aortic Stenosis Study.

Yan AT, Koh M, Chan KK, Guo H, Alter DA, Austin PC, Tu JV, Wijeysundera HC, Ko DT.

J Am Coll Cardiol. 2017 Mar 28;69(12):1523-1532. doi: 10.1016/j.jacc.2017.01.025.


Early non-persistence with dabigatran and rivaroxaban in patients with atrial fibrillation.

Jackevicius CA, Tsadok MA, Essebag V, Atzema C, Eisenberg MJ, Tu JV, Lu L, Rahme E, Ho PM, Turakhia M, Humphries KH, Behlouli H, Zhou L, Pilote L.

Heart. 2017 Sep;103(17):1331-1338. doi: 10.1136/heartjnl-2016-310672. Epub 2017 Mar 12.


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