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Items: 1 to 50 of 923

1.

Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation.

Charitou T, Srihari S, Lynn MA, Jarboui MA, Fasterius E, Moldovan M, Shirasawa S, Tsunoda T, Ueffing M, Xie J, Xin J, Wang X, Proud CG, Boldt K, Al-Khalili Szigyarto C, Kolch W, Lynn DJ.

Br J Cancer. 2019 May 28. doi: 10.1038/s41416-019-0477-7. [Epub ahead of print]

PMID:
31133691
2.

Xanthine oxidoreductase activity correlates with vascular endothelial dysfunction in patients with type 1 diabetes.

Washio K, Kusunoki Y, Tsunoda T, Osugi K, Ohigashi M, Murase T, Nakamura T, Matsuo T, Konishi K, Katsuno T, Namba M, Koyama H.

Acta Diabetol. 2019 May 15. doi: 10.1007/s00592-019-01362-1. [Epub ahead of print]

PMID:
31093763
3.

Author Correction: A missense mutation in the HECT domain of NEDD4L identified in a girl with periventricular nodular heterotopia, polymicrogyria, and cleft palate.

Kato K, Miya F, Hori I, Ieda D, Ohashi K, Negishi Y, Hattori A, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Saitoh S.

J Hum Genet. 2019 Apr 26. doi: 10.1038/s10038-019-0610-8. [Epub ahead of print]

PMID:
31028281
4.

HseSUMO: Sumoylation site prediction using half-sphere exposures of amino acids residues.

Sharma A, Lysenko A, López Y, Dehzangi A, Sharma R, Reddy H, Sattar A, Tsunoda T.

BMC Genomics. 2019 Apr 18;19(Suppl 9):982. doi: 10.1186/s12864-018-5206-8.

5.

EvolStruct-Phogly: incorporating structural properties and evolutionary information from profile bigrams for the phosphoglycerylation prediction.

Chandra AA, Sharma A, Dehzangi A, Tsunoda T.

BMC Genomics. 2019 Apr 18;19(Suppl 9):984. doi: 10.1186/s12864-018-5383-5.

6.

CD70 expression in tumor-associated fibroblasts predicts worse survival in colorectal cancer patients.

Inoue S, Ito H, Tsunoda T, Murakami H, Ebi M, Ogasawara N, Kasugai K, Kasai K, Ikeda H, Inaguma S.

Virchows Arch. 2019 Apr 13. doi: 10.1007/s00428-019-02565-1. [Epub ahead of print]

PMID:
30980190
7.

Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, and 5-fluorouracil.

Sekido M, Fujita KI, Kubota Y, Ishida H, Takahashi T, Ohkuma R, Tsunoda T, Ishikawa F, Shibanuma M, Sasaki Y.

Cancer Chemother Pharmacol. 2019 Jun;83(6):1127-1135. doi: 10.1007/s00280-019-03837-y. Epub 2019 Apr 9.

PMID:
30972456
8.

Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients.

Nitta S, Asahina Y, Kato T, Tsuchiya J, Inoue-Shinomiya E, Sato A, Tsunoda T, Miyoshi M, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Kakinuma S, Hikita H, Takehara T, Watanabe M.

Sci Rep. 2019 Apr 5;9(1):5722. doi: 10.1038/s41598-019-42114-z.

9.

Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium.

Tsunoda T, Kakinuma S, Miyoshi M, Kamiya A, Kaneko S, Sato A, Tsuchiya J, Nitta S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Sogo T, Komatsu H, Mukouchi R, Inui A, Fujisawa T, Nakauchi H, Asahina Y, Watanabe M.

J Hepatol. 2019 Jul;71(1):143-152. doi: 10.1016/j.jhep.2019.02.024. Epub 2019 Mar 19.

PMID:
30898581
10.

Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data.

Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S.

Commun Biol. 2019 Feb 25;2:77. doi: 10.1038/s42003-019-0324-7. eCollection 2019.

11.

LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells.

Miyoshi M, Kakinuma S, Kamiya A, Tsunoda T, Tsuchiya J, Sato A, Kaneko S, Nitta S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Nakauchi H, Asahina Y, Watanabe M.

Sci Rep. 2019 Feb 14;9(1):2072. doi: 10.1038/s41598-018-37430-9.

12.

A case of Niemann-Pick disease type C with neonatal liver failure initially diagnosed as neonatal hemochromatosis.

Kumagai T, Terashima H, Uchida H, Fukuda A, Kasahara M, Kosuga M, Okuyama T, Tsunoda T, Inui A, Fujisawa T, Narita A, Eto Y, Kubota M.

Brain Dev. 2019 May;41(5):460-464. doi: 10.1016/j.braindev.2019.01.004. Epub 2019 Feb 6.

13.

Altered upright face recognition and presence of face inversion effect in temporal lobe epilepsy: An event-related potential study.

Mogi T, Tsunoda T, Yoshino A.

Psychiatry Clin Neurosci. 2019 May;73(5):269-276. doi: 10.1111/pcn.12829. Epub 2019 Mar 14.

PMID:
30734399
14.

First detection of a Vssc allele V1016G conferring a high level of insecticide resistance in Aedes albopictus collected from Europe (Italy) and Asia (Vietnam), 2016: a new emerging threat to controlling arboviral diseases.

Kasai S, Caputo B, Tsunoda T, Cuong TC, Maekawa Y, Lam-Phua SG, Pichler V, Itokawa K, Murota K, Komagata O, Yoshida C, Chung HH, Bellini R, Tsuda Y, Teng HJ, Filho JLL, Alves LC, Ng LC, Minakawa N, Yen NT, Phong TV, Sawabe K, Tomita T.

Euro Surveill. 2019 Jan;24(5). doi: 10.2807/1560-7917.ES.2019.24.5.1700847.

15.

Discovering MoRFs by trisecting intrinsically disordered protein sequence into terminals and middle regions.

Sharma R, Sharma A, Patil A, Tsunoda T.

BMC Bioinformatics. 2019 Feb 4;19(Suppl 13):378. doi: 10.1186/s12859-018-2396-7.

16.

GlyStruct: glycation prediction using structural properties of amino acid residues.

Reddy HM, Sharma A, Dehzangi A, Shigemizu D, Chandra AA, Tsunoda T.

BMC Bioinformatics. 2019 Feb 4;19(Suppl 13):547. doi: 10.1186/s12859-018-2547-x.

17.

Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance.

Hirpara J, Eu JQ, Tan JKM, Wong AL, Clement MV, Kong LR, Ohi N, Tsunoda T, Qu J, Goh BC, Pervaiz S.

Redox Biol. 2018 Dec 17:101076. doi: 10.1016/j.redox.2018.101076. [Epub ahead of print]

18.

Diabetic Retinopathy as a Risk Factor Associated with the Development of Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease.

Azuma S, Asahina Y, Kakinuma S, Azuma K, Miyoshi M, Inoue E, Tsunoda T, Sato A, Kaneko S, Nagata H, Kawai-Kitahata F, Murakawa M, Nitta S, Itsui Y, Tomita M, Nakagawa M, Watanabe M.

Dig Dis. 2019;37(3):247-254. doi: 10.1159/000493580. Epub 2019 Jan 9.

PMID:
30625487
19.

Association of serum interferon-λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents.

Inoue-Shinomiya E, Murakawa M, Asahina Y, Nakagawa M, Tsuchiya J, Sato A, Tsunoda T, Miyoshi M, Nitta S, Kawai-Kitahata F, Itsui Y, Azuma S, Kakinuma S, Murata K, Mizokami M, Watanabe M.

Hepatol Res. 2019 May;49(5):500-511. doi: 10.1111/hepr.13307. Epub 2019 Feb 7.

PMID:
30623518
20.

MYCN de novo gain-of-function mutation in a patient with a novel megalencephaly syndrome.

Kato K, Miya F, Hamada N, Negishi Y, Narumi-Kishimoto Y, Ozawa H, Ito H, Hori I, Hattori A, Okamoto N, Kato M, Tsunoda T, Kanemura Y, Kosaki K, Takahashi Y, Nagata KI, Saitoh S.

J Med Genet. 2019 Jun;56(6):388-395. doi: 10.1136/jmedgenet-2018-105487. Epub 2018 Dec 20.

PMID:
30573562
21.

PhoglyStruct: Prediction of phosphoglycerylated lysine residues using structural properties of amino acids.

Chandra A, Sharma A, Dehzangi A, Ranganathan S, Jokhan A, Chou KC, Tsunoda T.

Sci Rep. 2018 Dec 18;8(1):17923. doi: 10.1038/s41598-018-36203-8.

22.

SumSec: Accurate Prediction of Sumoylation Sites Using Predicted Secondary Structure.

Dehzangi A, López Y, Taherzadeh G, Sharma A, Tsunoda T.

Molecules. 2018 Dec 10;23(12). pii: E3260. doi: 10.3390/molecules23123260.

23.

An integrative machine learning approach for prediction of toxicity-related drug safety.

Lysenko A, Sharma A, Boroevich KA, Tsunoda T.

Life Sci Alliance. 2018 Nov 28;1(6):e201800098. doi: 10.26508/lsa.201800098. eCollection 2018 Dec.

24.

Whole Genome Sequencing of a Vietnamese Family from a Dioxin Contamination Hotspot Reveals Novel Variants in the Son with Undiagnosed Intellectual Disability.

Nguyen DT, Nguyen HH, Nguyen TD, Nguyen TTH, Nakano K, Maejima K, Sasaki-Oku A, Nguyen VB, Nguyen DB, Le BQ, Wong JH, Tsunoda T, Nakagawa H, Fujimoto A, Nong VH.

Int J Environ Res Public Health. 2018 Nov 23;15(12). pii: E2629. doi: 10.3390/ijerph15122629.

25.

Relationship between occlusal force and condylar morphology in class II and III after bi-maxillary osteotomy.

Ueki K, Yoshizawa K, Moroi A, Tsutsui T, Hotta A, Hiraide R, Takayama A, Tsunoda T, Saito Y, Sato M, Baba N.

J Craniomaxillofac Surg. 2018 Dec;46(12):2103-2107. doi: 10.1016/j.jcms.2018.10.010. Epub 2018 Oct 22.

PMID:
30420148
26.

Gene expression dataset for whole cochlea of Macaca fascicularis.

Mutai H, Miya F, Shibata H, Yasutomi Y, Tsunoda T, Matsunaga T.

Sci Rep. 2018 Oct 22;8(1):15554. doi: 10.1038/s41598-018-33985-9.

27.

Histone deacetylase inhibitors sensitize 5-fluorouracil-resistant MDA-MB-468 breast cancer cells to 5-fluorouracil.

Minegaki T, Suzuki A, Mori M, Tsuji S, Yamamoto S, Watanabe A, Tsuzuki T, Tsunoda T, Yamamoto A, Tsujimoto M, Nishiguchi K.

Oncol Lett. 2018 Nov;16(5):6202-6208. doi: 10.3892/ol.2018.9388. Epub 2018 Sep 4.

28.

OPAL+: Length-Specific MoRF Prediction in Intrinsically Disordered Protein Sequences.

Sharma R, Sharma A, Raicar G, Tsunoda T, Patil A.

Proteomics. 2019 Mar;19(6):e1800058. doi: 10.1002/pmic.201800058. Epub 2018 Nov 2.

PMID:
30324701
29.

Lack of correlation between the costs of anticancer drugs and clinical benefits in Japan.

Satoh E, Sasaki Y, Ohkuma R, Takahashi T, Kubota Y, Ishida H, Hamada K, Kiuchi Y, Tsunoda T.

Cancer Sci. 2018 Dec;109(12):3896-3901. doi: 10.1111/cas.13831. Epub 2018 Nov 27.

30.

Acquisition of resistance to vemurafenib leads to interleukin-10 production through an aberrant activation of Akt in a melanoma cell line.

Inozume T, Tsunoda T, Morisaki T, Harada K, Shirasawa S, Kawamura T.

J Dermatol. 2018 Dec;45(12):1434-1439. doi: 10.1111/1346-8138.14651. Epub 2018 Sep 17.

PMID:
30222203
31.

Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models.

Otani T, Noma H, Sugasawa S, Kuchiba A, Goto A, Yamaji T, Kochi Y, Iwasaki M, Matsui S, Tsunoda T.

Eur J Hum Genet. 2019 Jan;27(1):140-149. doi: 10.1038/s41431-018-0251-y. Epub 2018 Sep 10.

PMID:
30202041
32.

A role of uroleuconaphins, polyketide red pigments in aphid, as a chemopreventor in the host defense system against infection with entomopathogenic fungi.

Horikawa M, Shimazu M, Aibe M, Kaku H, Inai M, Tsunoda T.

J Antibiot (Tokyo). 2018 Nov;71(12):992-999. doi: 10.1038/s41429-018-0093-4. Epub 2018 Aug 20.

PMID:
30127422
33.

Zfat expression in ZsGreen reporter gene knock‑in mice: Implications for a novel function of Zfat in definitive erythropoiesis.

Tsunoda T, Doi K, Ishikura S, Luo H, Nishi K, Matsuzaki H, Koyanagi M, Tanaka Y, Okamura T, Shirasawa S.

Int J Mol Med. 2018 Nov;42(5):2595-2603. doi: 10.3892/ijmm.2018.3806. Epub 2018 Aug 3.

34.

Genome-wide association study suggests four variants influencing outcomes with ranibizumab therapy in exudative age-related macular degeneration.

Akiyama M, Takahashi A, Momozawa Y, Arakawa S, Miya F, Tsunoda T, Ashikawa K, Oshima Y, Yasuda M, Yoshida S, Enaida H, Tan X, Yanagi Y, Yasukawa T, Ogura Y, Nagai Y, Takahashi K, Fujisawa K, Inoue M, Arakawa A, Tanaka K, Yuzawa M, Kadonosono K, Sonoda KH, Ishibashi T, Kubo M.

J Hum Genet. 2018 Oct;63(10):1083-1091. doi: 10.1038/s10038-018-0493-0. Epub 2018 Jul 27.

PMID:
30054556
35.

Mandibular bone healing after advancement or setback surgery using sagittal split ramus osteotomy.

Ueki K, Moroi A, Tsutsui T, Hotta A, Hiraide R, Takayama A, Tsunoda T, Saito Y, Sato M, Baba N, Yoshizawa K.

J Craniomaxillofac Surg. 2018 Sep;46(9):1500-1503. doi: 10.1016/j.jcms.2018.06.010. Epub 2018 Jun 13.

PMID:
30041994
36.

Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer's disease.

Yamaguchi-Kabata Y, Morihara T, Ohara T, Ninomiya T, Takahashi A, Akatsu H, Hashizume Y, Hayashi N, Shigemizu D, Boroevich KA, Ikeda M, Kubo M, Takeda M, Tsunoda T.

Hum Genet. 2018 Jul;137(6-7):521-533. doi: 10.1007/s00439-018-1906-z. Epub 2018 Jul 13.

37.

Sample Size for Successful Genome-Wide Association Study of Major Depressive Disorder.

Nishino J, Ochi H, Kochi Y, Tsunoda T, Matsui S.

Front Genet. 2018 Jun 28;9:227. doi: 10.3389/fgene.2018.00227. eCollection 2018.

38.

Publisher Correction: IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis.

Shigemizu D, Miya F, Akiyama S, Okuda S, Boroevich KA, Fujimoto A, Nakagawa H, Ozaki K, Niida S, Kanemura Y, Okamoto N, Saitoh S, Kato M, Yamasaki M, Matsunaga T, Mutai H, Kosaki K, Tsunoda T.

Sci Rep. 2018 Jul 4;8(1):10367. doi: 10.1038/s41598-018-28698-y.

39.

Growth Suppression of Human Colorectal Cancer Cells with Mutated KRAS by 3-Deaza-cytarabine in 3D Floating Culture.

Luo H, Nishi K, Ishikura S, Swain A, Morishige N, Yazaki R, Ohshima T, Shirasawa S, Tsunoda T.

Anticancer Res. 2018 Jul;38(7):4247-4256. doi: 10.21873/anticanres.12721.

PMID:
29970558
40.

Whole genome sequencing and mutation rate analysis of trios with paternal dioxin exposure.

Ton ND, Nakagawa H, Ha NH, Duong NT, Nhung VP, Hien LTT, Hue HTT, Hoang NH, Wong JH, Nakano K, Maejima K, Sasaki-Oku A, Tsunoda T, Fujimoto A, Van Hai N.

Hum Mutat. 2018 Oct;39(10):1384-1392. doi: 10.1002/humu.23585. Epub 2018 Jul 16.

PMID:
29969170
41.

A novel homozygous missense mutation in the SH3-binding motif of STAMBP causing microcephaly-capillary malformation syndrome.

Hori I, Miya F, Negishi Y, Hattori A, Ando N, Boroevich KA, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Saitoh S.

J Hum Genet. 2018 Sep;63(9):957-963. doi: 10.1038/s10038-018-0482-3. Epub 2018 Jun 15.

PMID:
29907875
42.

A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients.

Giraudet AL, Cassier PA, Iwao-Fukukawa C, Garin G, Badel JN, Kryza D, Chabaud S, Gilles-Afchain L, Clapisson G, Desuzinges C, Sarrut D, Halty A, Italiano A, Mori M, Tsunoda T, Katagiri T, Nakamura Y, Alberti L, Cropet C, Baconnier S, Berge-Montamat S, Pérol D, Blay JY.

BMC Cancer. 2018 Jun 8;18(1):646. doi: 10.1186/s12885-018-4544-x.

43.

A case report of reversible generalized seizures in a patient with Waardenburg syndrome associated with a novel nonsense mutation in the penultimate exon of SOX10.

Suzuki N, Mutai H, Miya F, Tsunoda T, Terashima H, Morimoto N, Matsunaga T.

BMC Pediatr. 2018 May 23;18(1):171. doi: 10.1186/s12887-018-1139-2.

44.

Enzyme Immobilization in Mesoporous Silica for Enhancement of Thermostability.

Matsuura SI, Chiba M, Tsunoda T, Yamaguchi A.

J Nanosci Nanotechnol. 2018 Jan 1;18(1):104-109. doi: 10.1166/jnn.2018.14580.

PMID:
29768820
45.

Empirical Bayes Estimation of Semi-parametric Hierarchical Mixture Models for Unbiased Characterization of Polygenic Disease Architectures.

Nishino J, Kochi Y, Shigemizu D, Kato M, Ikari K, Ochi H, Noma H, Matsui K, Morizono T, Boroevich KA, Tsunoda T, Matsui S.

Front Genet. 2018 Apr 24;9:115. doi: 10.3389/fgene.2018.00115. eCollection 2018.

46.

Structure-activity relationship of clovamide and its related compounds for the inhibition of amyloid β aggregation.

Tsunoda T, Takase M, Shigemori H.

Bioorg Med Chem. 2018 Jul 23;26(12):3202-3209. doi: 10.1016/j.bmc.2018.04.044. Epub 2018 Apr 22.

PMID:
29706525
47.

1,4-Dioxane degradation characteristics of Rhodococcus aetherivorans JCM 14343.

Inoue D, Tsunoda T, Yamamoto N, Ike M, Sei K.

Biodegradation. 2018 Jun;29(3):301-310. doi: 10.1007/s10532-018-9832-2. Epub 2018 Apr 25.

PMID:
29696449
48.

Navigating the disease landscape: knowledge representations for contextualizing molecular signatures.

Saqi M, Lysenko A, Guo YK, Tsunoda T, Auffray C.

Brief Bioinform. 2019 Mar 25;20(2):609-623. doi: 10.1093/bib/bby025.

49.

IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis.

Shigemizu D, Miya F, Akiyama S, Okuda S, Boroevich KA, Fujimoto A, Nakagawa H, Ozaki K, Niida S, Kanemura Y, Okamoto N, Saitoh S, Kato M, Yamasaki M, Matsunaga T, Mutai H, Kosaki K, Tsunoda T.

Sci Rep. 2018 Apr 4;8(1):5608. doi: 10.1038/s41598-018-23978-z. Erratum in: Sci Rep. 2018 Jul 4;8(1):10367.

50.

Dysbiosis of the salivary microbiota in pediatric-onset primary sclerosing cholangitis and its potential as a biomarker.

Iwasawa K, Suda W, Tsunoda T, Oikawa-Kawamoto M, Umetsu S, Takayasu L, Inui A, Fujisawa T, Morita H, Sogo T, Hattori M.

Sci Rep. 2018 Apr 3;8(1):5480. doi: 10.1038/s41598-018-23870-w.

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