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Items: 1 to 50 of 64

1.

Increased Lysosomal Exocytosis Induced by Lysosomal Ca2+ Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity.

Tsunemi T, Perez-Rosello T, Ishiguro Y, Yoroisaka A, Jeon S, Hamada K, Rammonhan M, Wong YC, Xie Z, Akamatsu W, Mazzulli JR, Surmeier DJ, Hattori N, Krainc D.

J Neurosci. 2019 Jul 17;39(29):5760-5772. doi: 10.1523/JNEUROSCI.3085-18.2019. Epub 2019 May 16.

PMID:
31097622
2.

Bilateral thigh compartment syndromes from extended sitting with forward bending.

Shimada T, Tsunemi T, Hattori A, Nakazato-Taniguchi T, Yasuhara H, Ogaki K, Hattori N.

J Clin Neurosci. 2019 Jun;64:35-37. doi: 10.1016/j.jocn.2019.03.027. Epub 2019 Apr 6.

PMID:
30967313
3.

Preliminary evidence of a paternal-maternal genetic conflict on the placenta: Link between imprinting disorder and multi-generational hypertensive disorders.

Naruse K, Tsunemi T, Kawahara N, Kobayashi H.

Placenta. 2019 Sep 1;84:69-73. doi: 10.1016/j.placenta.2019.02.009. Epub 2019 Feb 23. Review.

PMID:
30846225
4.

Differential Cross Section and Photon-Beam Asymmetry for the γ[over →]p → π^{-}Δ^{++}(1232) Reaction at Forward π^{-} Angles for E_{γ}=1.5-2.95  GeV.

Kohri H, Shiu SH, Chang WC, Yanai Y, Ahn DS, Ahn JK, Chen JY, Daté S, Ejiri H, Fujimura H, Fujiwara M, Fukui S, Gohn W, Hicks K, Hosaka A, Hotta T, Hwang SH, Imai K, Ishikawa T, Joo K, Kato Y, Kon Y, Lee HS, Maeda Y, Mibe T, Miyabe M, Morino Y, Muramatsu N, Nakano T, Nakatsugawa Y, Nam SI, Niiyama M, Noumi H, Ohashi Y, Ohta T, Oka M, Parker JD, Rangacharyulu C, Ryu SY, Sawada T, Shimizu H, Strokovsky EA, Sugaya Y, Sumihama M, Tsunemi T, Uchida M, Ungaro M, Wang SY, Yosoi M; LEPS Collaboration.

Phys Rev Lett. 2018 May 18;120(20):202004. doi: 10.1103/PhysRevLett.120.202004.

PMID:
29864366
5.

Comparison of the Different Definition Criteria for the Diagnosis of Amniotic Fluid Embolism.

Kobayashi H, Akasaka J, Naruse K, Sado T, Tsunemi T, Niiro E, Iwai K.

J Clin Diagn Res. 2017 Jul;11(7):QC18-QC21. doi: 10.7860/JCDR/2017/26746.10283. Epub 2017 Jul 1.

6.

The past changes and future perspectives on Parkinson's disease therapeutics in Japan.

Tsunemi T, Hattori N.

Nihon Rinsho. 2017 Jan;75(1):14-20. English, Japanese.

PMID:
30566289
7.

Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.

Mazzulli JR, Zunke F, Tsunemi T, Toker NJ, Jeon S, Burbulla LF, Patnaik S, Sidransky E, Marugan JJ, Sue CM, Krainc D.

J Neurosci. 2016 Jul 20;36(29):7693-706. doi: 10.1523/JNEUROSCI.0628-16.2016.

8.

Interference Effect between ϕ and Λ(1520) Production Channels in the γp→K^{+}K^{-}p Reaction near Threshold.

Ryu SY, Ahn JK, Nakano T, Ahn DS, Ajimura S, Akimune H, Asano Y, Chang WC, Chen JY, Daté S, Ejiri H, Fujimura H, Fujiwara M, Fukui S, Hasegawa S, Hicks K, Horie K, Hotta T, Hwang SH, Imai K, Ishikawa T, Iwata T, Kato Y, Kawai H, Kino K, Kohri H, Kon Y, Kumagai N, Lin PJ, Maeda Y, Makino S, Matsuda T, Matsuoka N, Mibe T, Miyabe M, Miyachi M, Morino Y, Muramatsu N, Murayama R, Nakatsugawa Y, Nam SI, Niiyama M, Nomachi M, Ohashi Y, Ohkuma H, Ohta T, Ooba T, Oshuev DS, Parker JD, Rangacharyulu C, Sakaguchi A, Sawada T, Shagin PM, Shiino Y, Shimizu H, Strokovsky EA, Sugaya Y, Sumihama M, Tokiyasu AO, Toi Y, Toyokawa H, Tsunemi T, Uchida M, Ungaro M, Wakai A, Wang CW, Wang SC, Yonehara K, Yorita T, Yoshimura M, Yosoi M, Zegers RG; LEPS Collaboration.

Phys Rev Lett. 2016 Jun 10;116(23):232001. doi: 10.1103/PhysRevLett.116.232001. Epub 2016 Jun 7.

PMID:
27341225
9.

Evaluation of vaginal fluid squamous cell carcinoma antigen test in diagnosis of premature rupture of membranes.

Koike N, Oi H, Naruse K, Tsunemi T, Akasaka J, Sado T, Kobayashi H.

J Matern Fetal Neonatal Med. 2017 Feb;30(3):334-337. Epub 2016 Apr 19.

PMID:
27095020
10.

Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway.

Song P, Trajkovic K, Tsunemi T, Krainc D.

J Neurosci. 2016 Feb 24;36(8):2425-37. doi: 10.1523/JNEUROSCI.2569-15.2016.

11.

PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.

Dickey AS, Pineda VV, Tsunemi T, Liu PP, Miranda HC, Gilmore-Hall SK, Lomas N, Sampat KR, Buttgereit A, Torres MJ, Flores AL, Arreola M, Arbez N, Akimov SS, Gaasterland T, Lazarowski ER, Ross CA, Yeo GW, Sopher BL, Magnuson GK, Pinkerton AB, Masliah E, La Spada AR.

Nat Med. 2016 Jan;22(1):37-45. doi: 10.1038/nm.4003. Epub 2015 Dec 7.

12.

Clinical, biochemical and molecular investigation of adult-onset glutaric acidemia type II: Characteristics in comparison with pediatric cases.

Yamada K, Kobayashi H, Bo R, Takahashi T, Purevsuren J, Hasegawa Y, Taketani T, Fukuda S, Ohkubo T, Yokota T, Watanabe M, Tsunemi T, Mizusawa H, Takuma H, Shioya A, Ishii A, Tamaoka A, Shigematsu Y, Sugie H, Yamaguchi S.

Brain Dev. 2016 Mar;38(3):293-301. doi: 10.1016/j.braindev.2015.08.011. Epub 2015 Sep 26.

PMID:
26403312
13.

Involvement of Visceral Adipose Tissue in Immunological Modulation of Inflammatory Cascade in Preeclampsia.

Naruse K, Akasaka J, Shigemitsu A, Tsunemi T, Koike N, Yoshimoto C, Kobayashi H.

Mediators Inflamm. 2015;2015:325932. doi: 10.1155/2015/325932. Epub 2015 May 31.

14.

ATP13A2/PARK9 regulates secretion of exosomes and α-synuclein.

Tsunemi T, Hamada K, Krainc D.

J Neurosci. 2014 Nov 12;34(46):15281-7. doi: 10.1523/JNEUROSCI.1629-14.2014.

15.

Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy.

Cortes CJ, Ling SC, Guo LT, Hung G, Tsunemi T, Ly L, Tokunaga S, Lopez E, Sopher BL, Bennett CF, Shelton GD, Cleveland DW, La Spada AR.

Neuron. 2014 Apr 16;82(2):295-307. doi: 10.1016/j.neuron.2014.03.001.

16.

Zn²⁺ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation.

Tsunemi T, Krainc D.

Hum Mol Genet. 2014 Jun 1;23(11):2791-801. doi: 10.1093/hmg/ddt572. Epub 2013 Dec 13.

17.

Predictor of mortality in patients with amniotic fluid embolism.

Oi H, Naruse K, Koike N, Tsunemi T, Shigetomi H, Kanayama N, Kobayashi H.

J Obstet Gynaecol Res. 2014 Apr;40(4):941-5. doi: 10.1111/jog.12278. Epub 2013 Dec 10.

PMID:
24320844
18.

New insights into the role of aminopeptidases in the treatment for both preeclampsia and preterm labor.

Mizutani S, Tsunemi T, Mizutani E, Hattori A, Tsujimoto M, Kobayashi H.

Expert Opin Investig Drugs. 2013 Nov;22(11):1425-36. doi: 10.1517/13543784.2013.825248. Epub 2013 Aug 10. Review.

PMID:
23931642
19.

S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease.

Haun F, Nakamura T, Shiu AD, Cho DH, Tsunemi T, Holland EA, La Spada AR, Lipton SA.

Antioxid Redox Signal. 2013 Oct 10;19(11):1173-84. doi: 10.1089/ars.2012.4928. Epub 2013 Jun 20.

20.

PP029. Genetic change of adipose tissue related to inflammation in preeclampsia: Findings under novel culture method.

Naruse K, Tsunemi T, Onogi A, Koike N, Akasaka J, Oi H, Kobayashi H.

Pregnancy Hypertens. 2013 Apr;3(2):77. doi: 10.1016/j.preghy.2013.04.056. Epub 2013 Jun 6.

PMID:
26105885
21.

Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.

Schultheis PJ, Fleming SM, Clippinger AK, Lewis J, Tsunemi T, Giasson B, Dickson DW, Mazzulli JR, Bardgett ME, Haik KL, Ekhator O, Chava AK, Howard J, Gannon M, Hoffman E, Chen Y, Prasad V, Linn SC, Tamargo RJ, Westbroek W, Sidransky E, Krainc D, Shull GE.

Hum Mol Genet. 2013 May 15;22(10):2067-82. doi: 10.1093/hmg/ddt057. Epub 2013 Feb 7.

22.

Pathogenesis and malignant transformation of adenomyosis (review).

Koike N, Tsunemi T, Uekuri C, Akasaka J, Ito F, Shigemitsu A, Kobayashi H.

Oncol Rep. 2013 Mar;29(3):861-7. doi: 10.3892/or.2012.2184. Epub 2012 Dec 13. Review.

PMID:
23242072
23.

The role of components of the chromatin modification machinery in carcinogenesis of clear cell carcinoma of the ovary (Review).

Shigetomi H, Oonogi A, Tsunemi T, Tanase Y, Yamada Y, Kajihara H, Yoshizawa Y, Furukawa N, Haruta S, Yoshida S, Sado T, Oi H, Kobayashi H.

Oncol Lett. 2011 Jul;2(4):591-597. Epub 2011 May 16.

24.

PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.

Tsunemi T, Ashe TD, Morrison BE, Soriano KR, Au J, Roque RA, Lazarowski ER, Damian VA, Masliah E, La Spada AR.

Sci Transl Med. 2012 Jul 11;4(142):142ra97. doi: 10.1126/scitranslmed.3003799.

25.

PP048. Questionnaire for obstetricians and neurosurgeons on brain stroke and hypertension in pregnancy in/around Nara Prefecture, Japan.

Naruse K, Yamada S, Noguchi T, Tsunemi T, Sado T, Suzuki Y, Nakase H, Kobayashi H.

Pregnancy Hypertens. 2012 Jul;2(3):267-8. doi: 10.1016/j.preghy.2012.04.159. Epub 2012 Jun 13.

PMID:
26105370
26.

Molecular mechanisms linking endometriosis under oxidative stress with ovarian tumorigenesis and therapeutic modalities.

Shigetomi H, Tsunemi T, Haruta S, Kajihara H, Yoshizawa Y, Tanase Y, Furukawa N, Yoshida S, Sado T, Kobayashi H.

Cancer Invest. 2012 Jul;30(6):473-80. doi: 10.3109/07357907.2012.681821. Epub 2012 Apr 25. Review.

PMID:
22530740
27.

Chemokine and free fatty acid levels in insulin-resistant state of successful pregnancy: a preliminary observation.

Naruse K, Noguchi T, Sado T, Tsunemi T, Shigetomi H, Kanayama S, Akasaka J, Koike N, Oi H, Kobayashi H.

Mediators Inflamm. 2012;2012:432575. doi: 10.1155/2012/432575. Epub 2012 Feb 9.

28.

Spin-density matrix elements for γp→K*0Σ+ at Eγ=1.85-3.0 GeV with evidence for the κ(800) meson exchange.

Hwang SH, Hicks K, Ahn JK, Nakano T, Ahn DS, Chang WC, Chen JY, Daté S, Ejiri H, Fujimura H, Fujiwara M, Fukui S, Gohn W, Hotta T, Imai K, Ishikawa T, Joo K, Kato Y, Kohri H, Kon Y, Lee HS, Maeda Y, Miyabe M, Mibe T, Morino Y, Muramatsu N, Nakatsugawa Y, Niiyama M, Noumi H, Oh Y, Ohashi Y, Ohta T, Oka M, Parker J, Rangacharyulu C, Ryu SY, Sawada T, Sugaya Y, Sumihama M, Tsunemi T, Uchida M, Ungaro M, Yosoi M; LEPS Collaboration.

Phys Rev Lett. 2012 Mar 2;108(9):092001. Epub 2012 Feb 27.

PMID:
22463625
29.

Peripheral RAGE (receptor for advanced glycation endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response.

Naruse K, Sado T, Noguchi T, Tsunemi T, Yoshida S, Akasaka J, Koike N, Oi H, Kobayashi H.

J Reprod Immunol. 2012 Mar;93(2):69-74. doi: 10.1016/j.jri.2011.12.003. Epub 2012 Mar 3.

PMID:
22382005
30.

Antiangiogenic-induced hypertension: the molecular basis of signaling network.

Nagai A, Sado T, Naruse K, Noguchi T, Haruta S, Yoshida S, Tanase Y, Tsunemi T, Kobayashi H.

Gynecol Obstet Invest. 2012;73(2):89-98. doi: 10.1159/000334458. Epub 2012 Jan 3. Review.

PMID:
22222493
31.

PGC-1α at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond.

Tsunemi T, La Spada AR.

Prog Neurobiol. 2012 May;97(2):142-51. doi: 10.1016/j.pneurobio.2011.10.004. Epub 2011 Nov 9. Review.

32.

Molecular genetics and epidemiology of epithelial ovarian cancer (Review).

Haruta S, Furukawa N, Yoshizawa Y, Tsunemi T, Nagai A, Kawaguchi R, Tanase Y, Yoshida S, Kobayashi H.

Oncol Rep. 2011 Dec;26(6):1347-56. doi: 10.3892/or.2011.1456. Epub 2011 Sep 12. Review.

PMID:
21922146
33.

Redox-active iron-induced oxidative stress in the pathogenesis of clear cell carcinoma of the ovary.

Yamada Y, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Yoshida S, Furukawa N, Nagai A, Tanase Y, Tsunemi T, Oi H, Kobayashi H.

Int J Gynecol Cancer. 2011 Oct;21(7):1200-7. doi: 10.1097/IGC.0b013e318222cfdd. Review.

PMID:
21885986
34.

Hypoxia inhibits invasion of extravillous trophoblast cells through reduction of matrix metalloproteinase (MMP)-2 activation in the early first trimester of human pregnancy.

Onogi A, Naruse K, Sado T, Tsunemi T, Shigetomi H, Noguchi T, Yamada Y, Akasaki M, Oi H, Kobayashi H.

Placenta. 2011 Sep;32(9):665-670. doi: 10.1016/j.placenta.2011.06.023. Epub 2011 Jul 20.

PMID:
21764444
35.

Increase of high molecular weight adiponectin in hypertensive pregnancy was correlated with brain-type natriuretic peptide stimulation on adipocyte.

Naruse K, Yamasaki Y, Tsunemi T, Onogi A, Noguchi T, Sado T, Oi H, Kobayashi H.

Pregnancy Hypertens. 2011 Jul-Oct;1(3-4):200-5. doi: 10.1016/j.preghy.2011.07.004. Epub 2011 Jul 26.

PMID:
26009027
36.

New insights into pattern recognition receptors and their ligands in gynecologic pathologies.

Yamada Y, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Yoshida S, Furukawa N, Nagai A, Tanase Y, Tsunemi T, Oi H, Kobayashi H.

Hum Immunol. 2011 Mar;72(3):213-8. doi: 10.1016/j.humimm.2010.12.009. Epub 2010 Dec 15. Review.

PMID:
21167248
37.

The effect of 3,4-diaminopyridine on the patients with hereditary pure cerebellar ataxia.

Tsunemi T, Ishikawa K, Tsukui K, Sumi T, Kitamura K, Mizusawa H.

J Neurol Sci. 2010 May 15;292(1-2):81-4. doi: 10.1016/j.jns.2010.01.021. Epub 2010 Feb 23.

PMID:
20181362
38.

Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n.

Sato N, Amino T, Kobayashi K, Asakawa S, Ishiguro T, Tsunemi T, Takahashi M, Matsuura T, Flanigan KM, Iwasaki S, Ishino F, Saito Y, Murayama S, Yoshida M, Hashizume Y, Takahashi Y, Tsuji S, Shimizu N, Toda T, Ishikawa K, Mizusawa H.

Am J Hum Genet. 2009 Nov;85(5):544-57. doi: 10.1016/j.ajhg.2009.09.019. Epub 2009 Oct 29.

39.

[Malignant lymphoma presented as left trigeminal neuralgia].

Akaza M, Tsunemi T, Sanjo N, Wakimoto H, Kobayashi D, Mizusawa H.

Rinsho Shinkeigaku. 2009 Jul;49(7):432-6. Review. Japanese.

PMID:
19715173
40.

18F-FDG PET successfully detects spinal cord sarcoidosis.

Ota K, Tsunemi T, Saito K, Yamanami F, Watanabe M, Irioka T, Mizusawa H.

J Neurol. 2009 Nov;256(11):1943-6. doi: 10.1007/s00415-009-5270-8. Epub 2009 Aug 14.

PMID:
19685103
41.

New measurement of the K+-->pi+ nunu branching ratio.

Artamonov AV, Bassalleck B, Bhuyan B, Blackmore EW, Bryman DA, Chen S, Chiang IH, Christidi IA, Cooper PS, Diwan MV, Frank JS, Fujiwara T, Hu J, Ives J, Jaffe DE, Kabe S, Kettell SH, Khabibullin MM, Khotjantsev AN, Kitching P, Kobayashi M, Komatsubara TK, Konaka A, Kozhevnikov AP, Kudenko YG, Kushnirenko A, Landsberg LG, Lewis B, Li KK, Littenberg LS, Macdonald JA, Mildenberger J, Mineev OV, Miyajima M, Mizouchi K, Mukhin VA, Muramatsu N, Nakano T, Nomachi M, Nomura T, Numao T, Obraztsov VF, Omata K, Patalakha DI, Petrenko SV, Poutissou R, Ramberg EJ, Redlinger G, Sato T, Sekiguchi T, Shinkawa T, Strand RC, Sugimoto S, Tamagawa Y, Tschirhart R, Tsunemi T, Vavilov DV, Viren B, Wang Z, Yershov NV, Yoshimura Y, Yoshioka T; E949 Collaboration.

Phys Rev Lett. 2008 Nov 7;101(19):191802. Epub 2008 Nov 7.

PMID:
19113260
42.

Cell-type-specific alternative splicing in spinocerebellar ataxia type 6.

Tsunemi T, Ishikawa K, Jin H, Mizusawa H.

Neurosci Lett. 2008 Dec 5;447(1):78-81. doi: 10.1016/j.neulet.2008.09.065. Epub 2008 Sep 30.

PMID:
18835329
43.

Total synthesis of leustroducsin B.

Miyashita K, Tsunemi T, Hosokawa T, Ikejiri M, Imanishi T.

J Org Chem. 2008 Jul 18;73(14):5360-70. doi: 10.1021/jo8005599. Epub 2008 Jun 13.

PMID:
18549287
44.

Analyses of copy number and mRNA expression level of the alpha-synuclein gene in multiple system atrophy.

Jin H, Ishikawa K, Tsunemi T, Ishiguro T, Amino T, Mizusawa H.

J Med Dent Sci. 2008 Mar;55(1):145-53.

PMID:
19845160
45.

Direct and accurate measurement of CAG repeat configuration in the ataxin-1 (ATXN-1) gene by "dual-fluorescence labeled PCR-restriction fragment length analysis".

Lin JX, Ishikawa K, Sakamoto M, Tsunemi T, Ishiguro T, Amino T, Toru S, Kondo I, Mizusawa H.

J Hum Genet. 2008;53(4):287-95. doi: 10.1007/s10038-007-0242-2. Epub 2008 Feb 27.

PMID:
18301861
46.

Reversible central neurogenic hyperventilation in an awake patient with multiple sclerosis.

Takahashi M, Tsunemi T, Miyayosi T, Mizusawa H.

J Neurol. 2007 Dec;254(12):1763-4. Epub 2007 Nov 21. No abstract available.

PMID:
18004639
47.

Redefining the disease locus of 16q22.1-linked autosomal dominant cerebellar ataxia.

Amino T, Ishikawa K, Toru S, Ishiguro T, Sato N, Tsunemi T, Murata M, Kobayashi K, Inazawa J, Toda T, Mizusawa H.

J Hum Genet. 2007;52(8):643-9. Epub 2007 Jul 5.

PMID:
17611710
48.

Spinal cord herniation which manifested stepwise deterioration.

Akaza M, Tsunemi T, Hotate M, Toru S, Mizusawa H.

Intern Med. 2007;46(8):537-8. Epub 2007 Apr 17. No abstract available.

49.
50.

An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5' untranslated region of the gene encoding a protein with spectrin repeat and Rho guanine-nucleotide exchange-factor domains.

Ishikawa K, Toru S, Tsunemi T, Li M, Kobayashi K, Yokota T, Amino T, Owada K, Fujigasaki H, Sakamoto M, Tomimitsu H, Takashima M, Kumagai J, Noguchi Y, Kawashima Y, Ohkoshi N, Ishida G, Gomyoda M, Yoshida M, Hashizume Y, Saito Y, Murayama S, Yamanouchi H, Mizutani T, Kondo I, Toda T, Mizusawa H.

Am J Hum Genet. 2005 Aug;77(2):280-96. Epub 2005 Jul 6.

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