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Items: 1 to 50 of 345

1.

Reciprocal Association between the Apical Junctional Complex and AMPK: A Promising Therapeutic Target for Epithelial/Endothelial Barrier Function?

Tsukita K, Yano T, Tamura A, Tsukita S.

Int J Mol Sci. 2019 Nov 29;20(23). pii: E6012. doi: 10.3390/ijms20236012. Review.

2.

Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice.

Ito C, Akutsu H, Yao R, Yoshida K, Yamatoya K, Mutoh T, Makino T, Aoyama K, Ishikawa H, Kunimoto K, Tsukita S, Noda T, Kikkawa M, Toshimori K.

Sci Rep. 2019 Oct 3;9(1):14249. doi: 10.1038/s41598-019-50516-2.

3.

R40.76 binds to the α domain of ZO-1: role of ZO-1 (α+) in epithelial differentiation and mechano-sensing.

Rouaud F, Vasileva E, Spadaro D, Tsukita S, Citi S.

Tissue Barriers. 2019;7(3):e1653748. doi: 10.1080/21688370.2019.1653748. Epub 2019 Aug 22.

4.

Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions.

Konishi S, Yano T, Tanaka H, Mizuno T, Kanoh H, Tsukita K, Namba T, Tamura A, Yonemura S, Gotoh S, Matsumoto H, Hirai T, Tsukita S.

Life Sci Alliance. 2019 Aug 9;2(4). pii: e201900414. doi: 10.26508/lsa.201900414. Print 2019 Aug.

5.

Publisher Correction: Claudin-3-deficient C57BL/6J mice display intact brain barriers.

Dias MC, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, Betsholtz C, Furuse M, Tsukita S, Engelhardt B.

Sci Rep. 2019 Jul 18;9(1):10702. doi: 10.1038/s41598-019-43511-0.

6.

Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori Infection.

Suzuki K, Sentani K, Tanaka H, Yano T, Suzuki K, Oshima M, Yasui W, Tamura A, Tsukita S.

Cell Mol Gastroenterol Hepatol. 2019;8(1):119-142. doi: 10.1016/j.jcmgh.2019.03.003. Epub 2019 Mar 23.

7.

Morphologic determinant of tight junctions revealed by claudin-3 structures.

Nakamura S, Irie K, Tanaka H, Nishikawa K, Suzuki H, Saitoh Y, Tamura A, Tsukita S, Fujiyoshi Y.

Nat Commun. 2019 Feb 18;10(1):816. doi: 10.1038/s41467-019-08760-7.

8.

Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5+ Stem Cells via Inhibition of Wnt and Notch Signaling.

Zha JM, Li HS, Lin Q, Kuo WT, Jiang ZH, Tsai PY, Ding N, Wu J, Xu SF, Wang YT, Pan J, Zhou XM, Chen K, Tao M, Odenwald MA, Tamura A, Tsukita S, Turner JR, He WQ.

Cell Mol Gastroenterol Hepatol. 2019;7(2):255-274. doi: 10.1016/j.jcmgh.2018.09.006. Epub 2018 Sep 18.

9.

The Claudins: From Tight Junctions to Biological Systems.

Tsukita S, Tanaka H, Tamura A.

Trends Biochem Sci. 2019 Feb;44(2):141-152. doi: 10.1016/j.tibs.2018.09.008. Epub 2018 Oct 25. Review.

PMID:
30665499
10.

Claudin-3-deficient C57BL/6J mice display intact brain barriers.

Castro Dias M, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, Betsholtz C, Furuse M, Tsukita S, Engelhardt B.

Sci Rep. 2019 Jan 18;9(1):203. doi: 10.1038/s41598-018-36731-3. Erratum in: Sci Rep. 2019 Jul 18;9(1):10702.

11.

Cep128 associates with Odf2 to form the subdistal appendage of the centriole.

Kashihara H, Chiba S, Kanno SI, Suzuki K, Yano T, Tsukita S.

Genes Cells. 2019 Mar;24(3):231-243. doi: 10.1111/gtc.12668. Epub 2019 Feb 18.

12.

Publisher Correction: AMPK-dependent phosphorylation of cingulin reversibly regulates its binding to actin filaments and microtubules.

Yano T, Torisawa T, Oiwa K, Tsukita S.

Sci Rep. 2018 Dec 17;8(1):17991. doi: 10.1038/s41598-018-37079-4.

13.

AMPK-dependent phosphorylation of cingulin reversibly regulates its binding to actin filaments and microtubules.

Yano T, Torisawa T, Oiwa K, Tsukita S.

Sci Rep. 2018 Oct 19;8(1):15550. doi: 10.1038/s41598-018-33418-7. Erratum in: Sci Rep. 2018 Dec 17;8(1):17991.

14.

Claudin-3 regulates bile canalicular paracellular barrier and cholesterol gallstone core formation in mice.

Tanaka H, Imasato M, Yamazaki Y, Matsumoto K, Kunimoto K, Delpierre J, Meyer K, Zerial M, Kitamura N, Watanabe M, Tamura A, Tsukita S.

J Hepatol. 2018 Dec;69(6):1308-1316. doi: 10.1016/j.jhep.2018.08.025. Epub 2018 Sep 11.

PMID:
30213590
15.

Deficient ganglioside synthesis restores responsiveness to leptin and melanocortin signaling in obese KKAy mice.

Inamori KI, Ito H, Tamura Y, Nitta T, Yang X, Nihei W, Shishido F, Imazu S, Tsukita S, Yamada T, Katagiri H, Inokuchi JI.

J Lipid Res. 2018 Aug;59(8):1472-1481. doi: 10.1194/jlr.M085753. Epub 2018 Jun 7.

16.

Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers.

Honma M, Sawada S, Ueno Y, Murakami K, Yamada T, Gao J, Kodama S, Izumi T, Takahashi K, Tsukita S, Uno K, Imai J, Kakazu E, Kondo Y, Mizuno K, Kawagishi N, Shimosegawa T, Katagiri H.

Int J Obes (Lond). 2018 Sep;42(9):1544-1555. doi: 10.1038/s41366-018-0062-9. Epub 2018 May 1.

17.

[Home Medical Care Promotion for Multidisciplinary Cooperation].

Midorikawa Y, Tamotsu K, Tsukita S, Kimura M, Yamauchi T.

Gan To Kagaku Ryoho. 2018 Mar;45(Suppl 1):58-60. Japanese.

PMID:
29650876
18.

Olfactory receptors are expressed in pancreatic β-cells and promote glucose-stimulated insulin secretion.

Munakata Y, Yamada T, Imai J, Takahashi K, Tsukita S, Shirai Y, Kodama S, Asai Y, Sugisawa T, Chiba Y, Kaneko K, Uno K, Sawada S, Hatakeyama H, Kanzaki M, Miyazaki JI, Oka Y, Katagiri H.

Sci Rep. 2018 Jan 24;8(1):1499. doi: 10.1038/s41598-018-19765-5.

19.

Claudin-3 Loss Causes Leakage of Sweat from the Sweat Gland to Contribute to the Pathogenesis of Atopic Dermatitis.

Yamaga K, Murota H, Tamura A, Miyata H, Ohmi M, Kikuta J, Ishii M, Tsukita S, Katayama I.

J Invest Dermatol. 2018 Jun;138(6):1279-1287. doi: 10.1016/j.jid.2017.11.040. Epub 2017 Dec 23.

20.

Site-specific distribution of claudin-based paracellular channels with roles in biological fluid flow and metabolism.

Tanaka H, Tamura A, Suzuki K, Tsukita S.

Ann N Y Acad Sci. 2017 Oct;1405(1):44-52. doi: 10.1111/nyas.13438. Epub 2017 Sep 4. Review.

PMID:
28869648
21.

Apical cytoskeletons and junctional complexes as a combined system in epithelial cell sheets.

Yano T, Kanoh H, Tamura A, Tsukita S.

Ann N Y Acad Sci. 2017 Oct;1405(1):32-43. doi: 10.1111/nyas.13432. Epub 2017 Aug 1. Review.

PMID:
28763830
22.

Time- and dose-dependent claudin contribution to biological functions: Lessons from claudin-1 in skin.

Tokumasu R, Tamura A, Tsukita S.

Tissue Barriers. 2017 Jul 3;5(3):e1336194. doi: 10.1080/21688370.2017.1336194. Epub 2017 Jun 19.

23.

IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance.

Tsai PY, Zhang B, He WQ, Zha JM, Odenwald MA, Singh G, Tamura A, Shen L, Sailer A, Yeruva S, Kuo WT, Fu YX, Tsukita S, Turner JR.

Cell Host Microbe. 2017 Jun 14;21(6):671-681.e4. doi: 10.1016/j.chom.2017.05.009.

24.

Interaction between Plasmodium Glycosylphosphatidylinositol and the Host Protein Moesin Has No Implication in Malaria Pathology.

Dunst J, Azzouz N, Liu X, Tsukita S, Seeberger PH, Kamena F.

Front Cell Infect Microbiol. 2017 May 16;7:183. doi: 10.3389/fcimb.2017.00183. eCollection 2017.

25.

Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity.

Horiuchi T, Sakata N, Narumi Y, Kimura T, Hayashi T, Nagano K, Liu K, Nishibori M, Tsukita S, Yamada T, Katagiri H, Shirakawa R, Horiuchi H.

J Biol Chem. 2017 May 19;292(20):8436-8446. doi: 10.1074/jbc.M116.769380. Epub 2017 Apr 3.

26.

Three-dimensional Organization of Layered Apical Cytoskeletal Networks Associated with Mouse Airway Tissue Development.

Tateishi K, Nishida T, Inoue K, Tsukita S.

Sci Rep. 2017 Mar 8;7:43783. doi: 10.1038/srep43783.

27.

ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity.

Suzuki T, Gao J, Ishigaki Y, Kondo K, Sawada S, Izumi T, Uno K, Kaneko K, Tsukita S, Takahashi K, Asao A, Ishii N, Imai J, Yamada T, Oyadomari S, Katagiri H.

Cell Rep. 2017 Feb 21;18(8):2045-2057. doi: 10.1016/j.celrep.2017.01.076.

28.

Activation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.

Asai Y, Yamada T, Tsukita S, Takahashi K, Maekawa M, Honma M, Ikeda M, Murakami K, Munakata Y, Shirai Y, Kodama S, Sugisawa T, Chiba Y, Kondo Y, Kaneko K, Uno K, Sawada S, Imai J, Nakamura Y, Yamaguchi H, Tanaka K, Sasano H, Mano N, Ueno Y, Shimosegawa T, Katagiri H.

Gastroenterology. 2017 May;152(6):1521-1535.e8. doi: 10.1053/j.gastro.2017.01.001. Epub 2017 Jan 11.

29.

MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic β-Cell Proliferation.

Tsukita S, Yamada T, Takahashi K, Munakata Y, Hosaka S, Takahashi H, Gao J, Shirai Y, Kodama S, Asai Y, Sugisawa T, Chiba Y, Kaneko K, Uno K, Sawada S, Imai J, Katagiri H.

EBioMedicine. 2017 Feb;15:163-172. doi: 10.1016/j.ebiom.2016.12.002. Epub 2016 Dec 7.

30.

Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton.

Herawati E, Taniguchi D, Kanoh H, Tateishi K, Ishihara S, Tsukita S.

J Cell Biol. 2016 Aug 29;214(5):571-86. doi: 10.1083/jcb.201601023.

31.

Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.

Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K.

Mucosal Immunol. 2017 Mar;10(2):446-459. doi: 10.1038/mi.2016.58. Epub 2016 Jul 6.

PMID:
27381925
32.

Presence of anti-phosphatidylserine-prothrombin complex antibodies and anti-moesin antibodies in patients with polyarteritis nodosa.

Okano T, Takeuchi S, Soma Y, Suzuki K, Tsukita S, Ishizu A, Suzuki K, Kawakami T.

J Dermatol. 2017 Jan;44(1):18-22. doi: 10.1111/1346-8138.13491. Epub 2016 Jun 27.

PMID:
27345569
33.

Dose-dependent role of claudin-1 in vivo in orchestrating features of atopic dermatitis.

Tokumasu R, Yamaga K, Yamazaki Y, Murota H, Suzuki K, Tamura A, Bando K, Furuta Y, Katayama I, Tsukita S.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):E4061-8. doi: 10.1073/pnas.1525474113. Epub 2016 Jun 24.

34.

Lipoprotein Lipase Deficiency (R243H) in a Type 2 Diabetes Patient with Multiple Arterial Aneurysms.

Suzuki T, Sawada S, Ishigaki Y, Tsukita S, Kodama S, Sugisawa T, Imai J, Yamada T, Yamaguchi T, Murano T, Katagiri H.

Intern Med. 2016;55(9):1131-6. doi: 10.2169/internalmedicine.55.5239. Epub 2016 May 1.

35.

Dapagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, Acutely Reduces Energy Expenditure in BAT via Neural Signals in Mice.

Chiba Y, Yamada T, Tsukita S, Takahashi K, Munakata Y, Shirai Y, Kodama S, Asai Y, Sugisawa T, Uno K, Sawada S, Imai J, Nakamura K, Katagiri H.

PLoS One. 2016 Mar 10;11(3):e0150756. doi: 10.1371/journal.pone.0150756. eCollection 2016.

36.

Claudin-21 Has a Paracellular Channel Role at Tight Junctions.

Tanaka H, Yamamoto Y, Kashihara H, Yamazaki Y, Tani K, Fujiyoshi Y, Mineta K, Takeuchi K, Tamura A, Tsukita S.

Mol Cell Biol. 2016 Jan 4;36(6):954-64. doi: 10.1128/MCB.00758-15.

37.

Directed Induction of Functional Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human Pluripotent Stem Cells.

Konishi S, Gotoh S, Tateishi K, Yamamoto Y, Korogi Y, Nagasaki T, Matsumoto H, Muro S, Hirai T, Ito I, Tsukita S, Mishima M.

Stem Cell Reports. 2016 Jan 12;6(1):18-25. doi: 10.1016/j.stemcr.2015.11.010. Epub 2015 Dec 24.

38.

Deletion of Tricellulin Causes Progressive Hearing Loss Associated with Degeneration of Cochlear Hair Cells.

Kamitani T, Sakaguchi H, Tamura A, Miyashita T, Yamazaki Y, Tokumasu R, Inamoto R, Matsubara A, Mori N, Hisa Y, Tsukita S.

Sci Rep. 2015 Dec 18;5:18402. doi: 10.1038/srep18402.

39.

Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory.

Hausrat TJ, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, Heisler FF, Herich L, Dubroqua S, Breiden P, Feldon J, Schwarz JR, Yee BK, Smart TG, Triller A, Kneussel M.

Nat Commun. 2015 Apr 20;6:6872. doi: 10.1038/ncomms7872.

40.

Fer tyrosine kinase oligomer mediates and amplifies Src-induced tumor progression.

Oneyama C, Yoshikawa Y, Ninomiya Y, Iino T, Tsukita S, Okada M.

Oncogene. 2016 Jan 28;35(4):501-12. doi: 10.1038/onc.2015.110. Epub 2015 Apr 13.

PMID:
25867068
41.

Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice.

Tanaka H, Takechi M, Kiyonari H, Shioi G, Tamura A, Tsukita S.

Gut. 2015 Oct;64(10):1529-38. doi: 10.1136/gutjnl-2014-308419. Epub 2015 Feb 17.

PMID:
25691495
42.

Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin.

Saitoh Y, Suzuki H, Tani K, Nishikawa K, Irie K, Ogura Y, Tamura A, Tsukita S, Fujiyoshi Y.

Science. 2015 Feb 13;347(6223):775-8. doi: 10.1126/science.1261833.

43.

Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient.

Liu X, Yang T, Suzuki K, Tsukita S, Ishii M, Zhou S, Wang G, Cao L, Qian F, Taylor S, Oh MJ, Levitan I, Ye RD, Carnegie GK, Zhao Y, Malik AB, Xu J.

J Exp Med. 2015 Feb 9;212(2):267-80. doi: 10.1084/jem.20140508. Epub 2015 Jan 19.

44.

Model for the architecture of claudin-based paracellular ion channels through tight junctions.

Suzuki H, Tani K, Tamura A, Tsukita S, Fujiyoshi Y.

J Mol Biol. 2015 Jan 30;427(2):291-7. doi: 10.1016/j.jmb.2014.10.020. Epub 2014 Nov 4.

45.

Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice.

Noda K, Nakajima S, Godo S, Saito H, Ikeda S, Shimizu T, Enkhjargal B, Fukumoto Y, Tsukita S, Yamada T, Katagiri H, Shimokawa H.

PLoS One. 2014 Nov 3;9(11):e110446. doi: 10.1371/journal.pone.0110446. eCollection 2014.

46.

Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice.

Hatano R, Akiyama K, Tamura A, Hosogi S, Marunaka Y, Caplan MJ, Ueno Y, Tsukita S, Asano S.

Hepatology. 2015 May;61(5):1660-71. doi: 10.1002/hep.27565. Epub 2015 Mar 23.

47.

Paracellular barrier and channel functions of TJ claudins in organizing biological systems: advances in the field of barriology revealed in knockout mice.

Tamura A, Tsukita S.

Semin Cell Dev Biol. 2014 Dec;36:177-85. doi: 10.1016/j.semcdb.2014.09.019. Epub 2014 Oct 12. Review.

PMID:
25305579
48.

Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.

Adachi M, Kawasaki A, Nojima H, Nishida E, Tsukita S.

Genes Cells. 2014 Nov;19(11):803-20. doi: 10.1111/gtc.12179. Epub 2014 Sep 17.

49.

Fetal growth retardation and lack of hypotaurine in ezrin knockout mice.

Nishimura T, Higuchi K, Sai Y, Sugita Y, Yoshida Y, Tomi M, Wada M, Wakayama T, Tamura A, Tsukita S, Soga T, Nakashima E.

PLoS One. 2014 Aug 21;9(8):e105423. doi: 10.1371/journal.pone.0105423. eCollection 2014.

50.

Ezrin mediates neuritogenesis via down-regulation of RhoA activity in cultured cortical neurons.

Matsumoto Y, Inden M, Tamura A, Hatano R, Tsukita S, Asano S.

PLoS One. 2014 Aug 21;9(8):e105435. doi: 10.1371/journal.pone.0105435. eCollection 2014.

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