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Items: 1 to 50 of 906

1.

Adalimumab Dose-Escalation Therapy Is Effective in Refractory Crohn's Disease Patients with Loss of Response to Adalimumab, Especially in Cases without Previous Infliximab Treatment.

Suzuki T, Mizoshita T, Sugiyama T, Hirata Y, Kimura Y, Suzuki Y, Yamada T, Tsukamoto H, Mizushima T, Sugimura N, Katano T, Tanida S, Kataoka H, Sasaki M.

Case Rep Gastroenterol. 2019 Feb 6;13(1):37-49. doi: 10.1159/000496453. eCollection 2019 Jan-Apr.

2.

The counterion-retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation.

Nagata T, Koyanagi M, Tsukamoto H, Mutt E, Schertler GFX, Deupi X, Terakita A.

Commun Biol. 2019 May 13;2:180. doi: 10.1038/s42003-019-0409-3. eCollection 2019.

3.

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease.

Kikuchi K, Saigusa D, Kanemitsu Y, Matsumoto Y, Thanai P, Suzuki N, Mise K, Yamaguchi H, Nakamura T, Asaji K, Mukawa C, Tsukamoto H, Sato T, Oikawa Y, Iwasaki T, Oe Y, Tsukimi T, Fukuda NN, Ho HJ, Nanto-Hara F, Ogura J, Saito R, Nagao S, Ohsaki Y, Shimada S, Suzuki T, Toyohara T, Mishima E, Shima H, Akiyama Y, Akiyama Y, Ichijo M, Matsuhashi T, Matsuo A, Ogata Y, Yang CC, Suzuki C, Breeggemann MC, Heymann J, Shimizu M, Ogawa S, Takahashi N, Suzuki T, Owada Y, Kure S, Mano N, Soga T, Wada T, Kopp JB, Fukuda S, Hozawa A, Yamamoto M, Ito S, Wada J, Tomioka Y, Abe T.

Nat Commun. 2019 Apr 23;10(1):1835. doi: 10.1038/s41467-019-09735-4.

4.

Cell Death and Liver Disease.

Aizawa S, Brar G, Tsukamoto H.

Gut Liver. 2019 Mar 19. doi: 10.5009/gnl18486. [Epub ahead of print]

5.

Nivolumab-induced colitis in a patient with malignant melanoma: A case report and immunological analysis.

Miyashita A, Fukushima S, Tsukamoto H, Itai H, Miyamoto H, Nakahara S, Kubo Y, Kimura T, Kuriyama H, Ihn H.

J Dermatol. 2019 Mar 25. doi: 10.1111/1346-8138.14857. [Epub ahead of print] No abstract available.

PMID:
30908699
6.

Impact of CD123 expression, analyzed by immunohistochemistry, on clinical outcomes in patients with acute myeloid leukemia.

Arai N, Homma M, Abe M, Baba Y, Murai S, Watanuki M, Kawaguchi Y, Fujiwara S, Kabasawa N, Tsukamoto H, Uto Y, Ariizumi H, Yanagisawa K, Hattori N, Saito B, Shiozawa E, Harada H, Yamochi-Onizuka T, Nakamaki T, Takimoto M.

Int J Hematol. 2019 May;109(5):539-544. doi: 10.1007/s12185-019-02616-y. Epub 2019 Mar 7.

PMID:
30847774
7.

Myocardial lipofuscin accumulation in ageing and sudden cardiac death.

Kakimoto Y, Okada C, Kawabe N, Sasaki A, Tsukamoto H, Nagao R, Osawa M.

Sci Rep. 2019 Mar 1;9(1):3304. doi: 10.1038/s41598-019-40250-0.

8.

Summary of the 2018 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Kuprys PV, Tsukamoto H, Gao B, Jia L, McGowan J, Coopersmith CM, Moreno MC, Hulsebus H, Meena AS, Souza-Smith FM, Roper P, Foster MT, Raju SV, Marshall SA, Fujita M, Curtis BJ, Wyatt TA, Mandrekar P, Kovacs EJ, Choudhry MA.

Alcohol. 2019 Jun;77:11-18. doi: 10.1016/j.alcohol.2018.08.010. Epub 2018 Aug 24. Review.

PMID:
30763905
9.

Impaired antigen-specific lymphocyte priming in mice after Toll-like receptor 4 activation via induction of monocytic myeloid-derived suppressor cells.

Tsukamoto H, Kozakai S, Kobayashi Y, Takanashi R, Aoyagi T, Numasaki M, Ohta S, Tomioka Y.

Eur J Immunol. 2019 Apr;49(4):546-563. doi: 10.1002/eji.201847805. Epub 2019 Feb 1.

PMID:
30671932
10.

CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan.

Ayano M, Tsukamoto H, Mitoma H, Kimoto Y, Akahoshi M, Arinobu Y, Miyamoto T, Horiuchi T, Niiro H, Nagafuji K, Harada M, Akashi K.

Arthritis Res Ther. 2019 Jan 22;21(1):30. doi: 10.1186/s13075-019-1823-0.

11.

Inflammatory pathways in alcoholic steatohepatitis.

Gao B, Ahmad MF, Nagy LE, Tsukamoto H.

J Hepatol. 2019 Feb;70(2):249-259. doi: 10.1016/j.jhep.2018.10.023. Review.

PMID:
30658726
12.

Alcoholic and non-alcoholic steatohepatitis: global perspective and emerging science.

Brar G, Tsukamoto H.

J Gastroenterol. 2019 Mar;54(3):218-225. doi: 10.1007/s00535-018-01542-w. Epub 2019 Jan 14. Review.

13.

Monitoring TIGIT/DNAM-1 and PVR/PVRL2 Immune Checkpoint Expression Levels in Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia.

Hattori N, Kawaguchi Y, Sasaki Y, Shimada S, Murai S, Abe M, Baba Y, Watanuki M, Fujiwara S, Arai N, Kabasawa N, Tsukamoto H, Uto Y, Yanagisawa K, Saito B, Harada H, Nakamaki T.

Biol Blood Marrow Transplant. 2019 May;25(5):861-867. doi: 10.1016/j.bbmt.2019.01.013. Epub 2019 Jan 11.

PMID:
30639819
14.

[Syndrome of inappropriate secretion of antidiuretic hormone in multiple myeloma patients treated with bortezomib, lenalidomide, and dexamethasone combination therapy].

Baba Y, Harada H, Shimada S, Sasaki Y, Murai S, Abe M, Fujiwara S, Arai N, Kawaguchi Y, Kabasawa N, Tsukamoto H, Uto Y, Ariizumi H, Yanagisawa K, Hattori N, Saito B, Nakamaki T.

Rinsho Ketsueki. 2018;59(11):2423-2427. doi: 10.11406/rinketsu.59.2423. Japanese.

PMID:
30531137
15.

Long-term efficacy of infliximab treatment and the predictors of treatment outcomes in patients with refractory uveitis associated with Behçet's disease.

Ueda S, Akahoshi M, Takeda A, Inoue Y, Omoto A, Ayano M, Kimoto Y, Mitoma H, Arinobu Y, Niiro H, Tsukamoto H, Horiuchi T, Hikita SI, Fukuhara T, Ishibashi T, Sonoda KH, Akashi K.

Eur J Rheumatol. 2018 Mar;5(1):9-15. doi: 10.5152/eurjrheum.2017.17068.

16.

Influence of UGT1A1 polymorphism on etoposide plus platinum-induced neutropenia in Japanese patients with small-cell lung cancer.

Negoro Y, Yano R, Yoshimura M, Suehiro Y, Yamashita S, Kodawara T, Watanabe K, Tsukamoto H, Nakamura T, Kadowaki M, Morikawa M, Umeda Y, Anzai M, Ishizuka T, Goto N.

Int J Clin Oncol. 2019 Mar;24(3):256-261. doi: 10.1007/s10147-018-1358-4. Epub 2018 Oct 17.

PMID:
30328531
17.

Dynamic Cerebral Autoregulation Is Maintained during High-Intensity Interval Exercise.

Tsukamoto H, Hashimoto T, Olesen ND, Petersen LG, Sørensen H, Nielsen HB, Secher NH, Ogoh S.

Med Sci Sports Exerc. 2019 Feb;51(2):372-378. doi: 10.1249/MSS.0000000000001792.

PMID:
30252775
18.

Impact of endoscopic ultrasound-guided fine-needle biopsy on the diagnosis of subepithelial tumors: A propensity score-matching analysis.

Inoue T, Okumura F, Sano H, Mizushima T, Tsukamoto H, Fujita Y, Ibusuki M, Kitano R, Kobayashi Y, Ishii N, Ito K, Yoneda M.

Dig Endosc. 2019 Mar;31(2):156-163. doi: 10.1111/den.13269. Epub 2018 Oct 3.

PMID:
30171772
19.

Publisher Correction: Alcoholic liver disease.

Seitz HK, Bataller R, Cortez-Pinto H, Gao B, Gual A, Lackner C, Mathurin P, Mueller S, Szabo G, Tsukamoto H.

Nat Rev Dis Primers. 2018 Aug 28;4(1):18. doi: 10.1038/s41572-018-0021-8.

PMID:
30154473
20.

Alcoholic liver disease.

Seitz HK, Bataller R, Cortez-Pinto H, Gao B, Gual A, Lackner C, Mathurin P, Mueller S, Szabo G, Tsukamoto H.

Nat Rev Dis Primers. 2018 Aug 16;4(1):16. doi: 10.1038/s41572-018-0014-7. Review. Erratum in: Nat Rev Dis Primers. 2018 Aug 28;4(1):18.

PMID:
30115921
21.

Effect of acetamiprid on the immature murine testes.

Terayama H, Qu N, Endo H, Ito M, Tsukamoto H, Umemoto K, Kawakami S, Fujino Y, Tatemichi M, Sakabe K.

Int J Environ Health Res. 2018 Dec;28(6):683-696. doi: 10.1080/09603123.2018.1504897. Epub 2018 Aug 13.

PMID:
30103633
22.

Generation and Characterization of Anti-phenyl Sulfate Monoclonal Antibodies and a Potential Use for Phenyl Sulfate Analysis in Human Blood.

Kanemitsu Y, Tsukamoto H, Matsumoto Y, Nozawa-Kumada K, Kondo Y, Abe T, Tomioka Y.

Biol Pharm Bull. 2018;41(8):1170-1177. doi: 10.1248/bpb.b17-00925.

23.

Vaccination strategy for epidemic viral diseases in healthcare workers: Cut-off for optimal immunization.

Yoshioka N, Deguchi M, Hagiya H, Kagita M, Tsukamoto H, Takao M, Tomono K.

J Infect Chemother. 2019 Jan;25(1):78-81. doi: 10.1016/j.jiac.2018.07.008. Epub 2018 Jul 29.

PMID:
30064948
24.

Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment.

Tsukamoto H, Fujieda K, Miyashita A, Fukushima S, Ikeda T, Kubo Y, Senju S, Ihn H, Nishimura Y, Oshiumi H.

Cancer Res. 2018 Sep 1;78(17):5011-5022. doi: 10.1158/0008-5472.CAN-18-0118. Epub 2018 Jul 2.

PMID:
29967259
25.

Total Synthesis of Spiromamakone A and Structure Revision of Spiropreussione A.

Tsukamoto H, Hanada S, Nomura Y, Doi T.

J Org Chem. 2018 Aug 17;83(16):9430-9441. doi: 10.1021/acs.joc.8b01075. Epub 2018 Jul 2.

PMID:
29895147
26.

Self-selected music-induced reduction of perceived exertion during moderate-intensity exercise does not interfere with post-exercise improvements in inhibitory control.

Tanaka D, Tsukamoto H, Suga T, Takenaka S, Hamaoka T, Hashimoto T, Isaka T.

Physiol Behav. 2018 Oct 1;194:170-176. doi: 10.1016/j.physbeh.2018.05.030. Epub 2018 May 26.

PMID:
29807054
27.

Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKϵ-IRF3 axis activation.

Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.

J Biol Chem. 2018 Jun 29;293(26):10186-10201. doi: 10.1074/jbc.M117.796631. Epub 2018 May 14.

PMID:
29760187
28.

Status of Natural Killer Cell Recovery in Day 21 Bone Marrow after Allogeneic Hematopoietic Stem Cell Transplantation Predicts Clinical Outcome.

Hattori N, Saito B, Sasaki Y, Shimada S, Murai S, Abe M, Baba Y, Watanuki M, Fujiwara S, Kawaguchi Y, Arai N, Kabasawa N, Tsukamoto H, Uto Y, Ariizumi H, Yanagisawa K, Harada H, Nakamaki T.

Biol Blood Marrow Transplant. 2018 Sep;24(9):1841-1847. doi: 10.1016/j.bbmt.2018.05.007. Epub 2018 May 16.

PMID:
29753837
29.

Conjugate Addition to Acylketene Acetals Derived from 1,8-Dihydroxynaphthalene and Its Application To Synthesize the Proposed Structure of Spiropreussione A.

Tsukamoto H, Nomura Y, Fujiwara K, Hanada S, Doi T.

Org Lett. 2018 May 18;20(10):3140-3143. doi: 10.1021/acs.orglett.8b01259. Epub 2018 May 8.

PMID:
29737863
30.

Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor-Initiating Stem Cell-Like Cells Resistant to mTORC1 Inhibition.

Wu R, Murali R, Kabe Y, French SW, Chiang YM, Liu S, Sher L, Wang CC, Louie S, Tsukamoto H.

Hepatology. 2018 Nov;68(5):1726-1740. doi: 10.1002/hep.30071. Epub 2018 Oct 9.

PMID:
29729190
31.

Synthesis of multi-substituted dihydrofurans via palladium-catalysed coupling between 2,3-alkadienols and pronucleophiles.

Tsukamoto H, Ito K, Doi T.

Chem Commun (Camb). 2018 May 15;54(40):5102-5105. doi: 10.1039/c8cc02589d.

PMID:
29714394
32.

Activation of TLR3 and its adaptor TICAM-1 increases miR-21 levels in extracellular vesicles released from human cells.

Fukushima Y, Okamoto M, Ishikawa K, Kouwaki T, Tsukamoto H, Oshiumi H.

Biochem Biophys Res Commun. 2018 Jun 7;500(3):744-750. doi: 10.1016/j.bbrc.2018.04.146. Epub 2018 Apr 23.

PMID:
29679565
33.

A Go-type opsin mediates the shadow reflex in the annelid Platynereis dumerilii.

Ayers T, Tsukamoto H, Gühmann M, Veedin Rajan VB, Tessmar-Raible K.

BMC Biol. 2018 Apr 18;16(1):41. doi: 10.1186/s12915-018-0505-8.

34.

Loss of Stemness, EMT, and Supernumerary Tooth Formation in Cebpb-/-Runx2+/- Murine Incisors.

Saito K, Takahashi K, Huang B, Asahara M, Kiso H, Togo Y, Tsukamoto H, Mishima S, Nagata M, Iida M, Tokita Y, Asai M, Shimizu A, Komori T, Harada H, MacDougall M, Sugai M, Bessho K.

Sci Rep. 2018 Mar 26;8(1):5169. doi: 10.1038/s41598-018-23515-y.

35.

Structural properties determining low K+ affinity of the selectivity filter in the TWIK1 K+ channel.

Tsukamoto H, Higashi M, Motoki H, Watanabe H, Ganser C, Nakajo K, Kubo Y, Uchihashi T, Furutani Y.

J Biol Chem. 2018 May 4;293(18):6969-6984. doi: 10.1074/jbc.RA118.001817. Epub 2018 Mar 15.

36.

Association of red cell distribution width with clinical outcomes in myelodysplastic syndrome.

Baba Y, Saito B, Shimada S, Sasaki Y, Murai S, Abe M, Fujiwara S, Arai N, Kawaguchi Y, Kabasawa N, Tsukamoto H, Uto Y, Ariizumi H, Yanagisawa K, Hattori N, Harada H, Nakamaki T.

Leuk Res. 2018 Apr;67:56-59. doi: 10.1016/j.leukres.2018.02.004. Epub 2018 Feb 7.

37.

Serum apolipoprotein E may be a novel biomarker of migraine.

Yuasa N, Nagata E, Fujii N, Ito M, Tsukamoto H, Takizawa S.

PLoS One. 2018 Jan 22;13(1):e0190620. doi: 10.1371/journal.pone.0190620. eCollection 2018.

38.

Association of Soluble Interleukin-2 Receptor and C-Reactive Protein with the Efficacy of Bendamustine Salvage Treatment for Indolent Lymphomas and Mantle Cell Lymphoma.

Kawaguchi Y, Nakamaki T, Abe M, Baba Y, Murai S, Watanuki M, Arai N, Fujiwara S, Kabasawa N, Tsukamoto H, Uto Y, Ariizumi H, Yanagisawa K, Hattori N, Harada H, Saito B.

Acta Haematol. 2018;139(1):12-18. doi: 10.1159/000484711. Epub 2018 Jan 5.

PMID:
29301121
39.

Flavanol-rich cocoa consumption enhances exercise-induced executive function improvements in humans.

Tsukamoto H, Suga T, Ishibashi A, Takenaka S, Tanaka D, Hirano Y, Hamaoka T, Goto K, Ebi K, Isaka T, Hashimoto T.

Nutrition. 2018 Feb;46:90-96. doi: 10.1016/j.nut.2017.08.017. Epub 2017 Sep 28.

PMID:
29290363
40.

Beneficial use of serum ferritin and heme oxygenase-1 as biomarkers in adult-onset Still's disease: A multicenter retrospective study.

Kirino Y, Kawaguchi Y, Tada Y, Tsukamoto H, Ota T, Iwamoto M, Takahashi H, Nagasawa K, Takei S, Horiuchi T, Ichida H, Minota S, Ueda A, Ohta A, Ishigatsubo Y.

Mod Rheumatol. 2018 Sep;28(5):858-864. doi: 10.1080/14397595.2017.1422231. Epub 2018 Jan 11.

PMID:
29278009
41.

Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model.

Mishima E, Fukuda S, Kanemitsu Y, Saigusa D, Mukawa C, Asaji K, Matsumoto Y, Tsukamoto H, Tachikawa T, Tsukimi T, Fukuda NN, Ho HJ, Kikuchi K, Suzuki C, Nanto F, Suzuki T, Ito S, Soga T, Tomioka Y, Abe T.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F824-F833. doi: 10.1152/ajprenal.00314.2017. Epub 2017 Nov 22.

PMID:
29167170
42.

Maintained exercise-enhanced brain executive function related to cerebral lactate metabolism in men.

Hashimoto T, Tsukamoto H, Takenaka S, Olesen ND, Petersen LG, Sørensen H, Nielsen HB, Secher NH, Ogoh S.

FASEB J. 2018 Mar;32(3):1417-1427. doi: 10.1096/fj.201700381RR. Epub 2018 Jan 3.

PMID:
29127193
43.

Durability of immunity by hepatitis B vaccine in Japanese health care workers depends on primary response titers and durations.

Yoshioka N, Deguchi M, Hagiya H, Kagita M, Tsukamoto H, Takao M, Yoshida H, Yamamoto N, Akeda Y, Nabetani Y, Maeda I, Hidaka Y, Tomono K.

PLoS One. 2017 Nov 9;12(11):e0187661. doi: 10.1371/journal.pone.0187661. eCollection 2017.

44.

Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients.

Khanova E, Wu R, Wang W, Yan R, Chen Y, French SW, Llorente C, Pan SQ, Yang Q, Li Y, Lazaro R, Ansong C, Smith RD, Bataller R, Morgan T, Schnabl B, Tsukamoto H.

Hepatology. 2018 May;67(5):1737-1753. doi: 10.1002/hep.29645. Epub 2018 Feb 27.

45.

Immune-suppressive effects of interleukin-6 on T-cell-mediated anti-tumor immunity.

Tsukamoto H, Fujieda K, Senju S, Ikeda T, Oshiumi H, Nishimura Y.

Cancer Sci. 2018 Mar;109(3):523-530. doi: 10.1111/cas.13433. Epub 2017 Nov 16. Review.

46.

Quantitative muscle ultrasound is useful for evaluating secondary axonal degeneration in chronic inflammatory demyelinating polyneuropathy.

Hokkoku K, Matsukura K, Uchida Y, Kuwabara M, Furukawa Y, Tsukamoto H, Hatanaka Y, Sonoo M.

Brain Behav. 2017 Sep 15;7(10):e00812. doi: 10.1002/brb3.812. eCollection 2017 Oct.

47.

Ca2+ -dependent down-regulation of human histamine H1 receptors in Chinese hamster ovary cells.

Hishinuma S, Komazaki H, Tsukamoto H, Hatahara H, Fukui H, Shoji M.

J Neurochem. 2018 Jan;144(1):68-80. doi: 10.1111/jnc.14245. Epub 2017 Nov 21.

48.

Simultaneous quantitative analysis of uremic toxins by LC-MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column.

Kanemitsu Y, Asaji K, Matsumoto Y, Tsukamoto H, Saigusa D, Mukawa C, Tachikawa T, Abe T, Tomioka Y.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Nov 15;1068-1069:1-8. doi: 10.1016/j.jchromb.2017.10.009. Epub 2017 Oct 5.

PMID:
29024911
49.

Sudden Respiratory Failure due to Tracheobronchomalacia by Relapsing Polychondritis, Successfully Rescued by Multiple Metallic Stenting and Tracheostomy.

Oryoji D, Ono N, Himeji D, Yoshihiro K, Kai Y, Matsuda M, Tsukamoto H, Ueda A.

Intern Med. 2017 Dec 15;56(24):3369-3372. doi: 10.2169/internalmedicine.8778-16. Epub 2017 Oct 11.

50.

Evaluation of the highly sensitive chemiluminescent enzyme immunoassay "Lumipulse HBsAg-HQ" for hepatitis B virus screening.

Deguchi M, Kagita M, Yoshioka N, Tsukamoto H, Takao M, Tahara K, Maeda I, Hidaka Y, Yamauchi S, Kaneko A, Miyakoshi H, Isomura M.

J Clin Lab Anal. 2018 May;32(4):e22334. doi: 10.1002/jcla.22334. Epub 2017 Oct 6.

PMID:
28984383

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