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Social anxiety and negative symptoms as the characteristics of patients with schizophrenia who show competence-performance discrepancy in social functioning.

Nemoto T, Uchino T, Aikawa S, Saito J, Matsumoto H, Funatogawa T, Yamaguchi T, Katagiri N, Tsujino N, Mizuno M.

Psychiatry Clin Neurosci. 2019 Apr 9. doi: 10.1111/pcn.12848. [Epub ahead of print]


Effectiveness of Kangaroo Care for a Patient with Postpartum Depression and Comorbid Mother-Infant Bonding Disorder.

Takubo Y, Nemoto T, Obata Y, Baba Y, Yamaguchi T, Katagiri N, Tsujino N, Kitamura T, Mizuno M.

Case Rep Psychiatry. 2019 Feb 25;2019:9157214. doi: 10.1155/2019/9157214. eCollection 2019.


Longitudinal changes in striatum and sub-threshold positive symptoms in individuals with an 'at risk mental state' (ARMS).

Katagiri N, Pantelis C, Nemoto T, Tsujino N, Saito J, Hori M, Yamaguchi T, Funatogawa T, Mizuno M.

Psychiatry Res Neuroimaging. 2019 Mar 30;285:25-30. doi: 10.1016/j.pscychresns.2019.01.008. Epub 2019 Jan 30.


Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture.

Saito YC, Tsujino N, Abe M, Yamazaki M, Sakimura K, Sakurai T.

Front Neurosci. 2018 Nov 30;12:892. doi: 10.3389/fnins.2018.00892. eCollection 2018.


Psychiatrists' opinion towards medication discontinuation in remitted first-episode psychosis: A multi-site study of the Asian Network for Early Psychosis.

Hui CL, Wong AK, Leung WW, Lee EH, Chan SK, Chang WC, Chen EY, Chan TC, Swapna V, Tagata H, Tsujino N, Nemoto T, Mizuno M, Kang NI, Kim SW, Chung YC.

Early Interv Psychiatry. 2018 Nov 28. doi: 10.1111/eip.12765. [Epub ahead of print]


Prediction of remission in pharmacotherapy of untreated major depression: development and validation of multivariable prediction models.

Furukawa TA, Kato T, Shinagawa Y, Miki K, Fujita H, Tsujino N, Kondo M, Inagaki M, Yamada M.

Psychol Med. 2018 Nov 15:1-9. doi: 10.1017/S0033291718003331. [Epub ahead of print]


Federated multi-site longitudinal study of at-risk mental state for psychosis in Japan.

Matsumoto K, Katsura M, Tsujino N, Nishiyama S, Nemoto T, Katagiri N, Takahashi T, Higuchi Y, Ohmuro N, Matsuoka H, Suzuki M, Mizuno M.

Schizophr Res. 2019 Feb;204:343-352. doi: 10.1016/j.schres.2018.09.001. Epub 2018 Sep 13.


Optimising first- and second-line treatment strategies for untreated major depressive disorder - the SUN☺D study: a pragmatic, multi-centre, assessor-blinded randomised controlled trial.

Kato T, Furukawa TA, Mantani A, Kurata K, Kubouchi H, Hirota S, Sato H, Sugishita K, Chino B, Itoh K, Ikeda Y, Shinagawa Y, Kondo M, Okamoto Y, Fujita H, Suga M, Yasumoto S, Tsujino N, Inoue T, Fujise N, Akechi T, Yamada M, Shimodera S, Watanabe N, Inagaki M, Miki K, Ogawa Y, Takeshima N, Hayasaka Y, Tajika A, Shinohara K, Yonemoto N, Tanaka S, Zhou Q, Guyatt GH; SUN☺D Investigators.

BMC Med. 2018 Jul 11;16(1):103. doi: 10.1186/s12916-018-1096-5.


Complete agreement of the post-spinel transition with the 660-km seismic discontinuity.

Ishii T, Huang R, Fei H, Koemets I, Liu Z, Maeda F, Yuan L, Wang L, Druzhbin D, Yamamoto T, Bhat S, Farla R, Kawazoe T, Tsujino N, Kulik E, Higo Y, Tange Y, Katsura T.

Sci Rep. 2018 Apr 20;8(1):6358. doi: 10.1038/s41598-018-24832-y.


Social anxiety and risk factors in patients with schizophrenia: Relationship with duration of untreated psychosis.

Aikawa S, Kobayashi H, Nemoto T, Matsuo S, Wada Y, Mamiya N, Yamaguchi T, Katagiri N, Tsujino N, Mizuno M.

Psychiatry Res. 2018 May;263:94-100. doi: 10.1016/j.psychres.2018.02.038. Epub 2018 Feb 20.


Survey of recognition and treatment of at-risk mental state by Japanese psychiatrists.

Tsujino N, Tagata H, Baba Y, Kojima A, Yamaguchi T, Katagiri N, Nemoto T, Mizuno M.

Psychiatry Clin Neurosci. 2018 Jun;72(6):391-398. doi: 10.1111/pcn.12647. Epub 2018 Mar 23.


Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting.

Matsumoto K, Ohmuro N, Tsujino N, Nishiyama S, Abe K, Hamaie Y, Katsura M, Inoue N, Matsuoka H, Kawasaki Y, Kishimoto T, Suzuki M, Mizuno M.

Early Interv Psychiatry. 2019 Feb;13(1):137-141. doi: 10.1111/eip.12541. Epub 2018 Jan 22.


Cognitive and Behavioral Skills Exercises Completed by Patients with Major Depression During Smartphone Cognitive Behavioral Therapy: Secondary Analysis of a Randomized Controlled Trial.

Furukawa TA, Horikoshi M, Fujita H, Tsujino N, Jinnin R, Kako Y, Ogawa S, Sato H, Kitagawa N, Shinagawa Y, Ikeda Y, Imai H, Tajika A, Ogawa Y, Akechi T, Yamada M, Shimodera S, Watanabe N, Inagaki M, Hasegawa A.

JMIR Ment Health. 2018 Jan 11;5(1):e4. doi: 10.2196/mental.9092.


Symptom recovery and relationship to structure of corpus callosum in individuals with an 'at risk mental state'.

Katagiri N, Pantelis C, Nemoto T, Tsujino N, Saito J, Hori M, Yamaguchi T, Funatogawa T, Mizuno M.

Psychiatry Res Neuroimaging. 2018 Feb 28;272:1-6. doi: 10.1016/j.pscychresns.2017.11.016. Epub 2017 Nov 29.


Synthesis of boron-doped diamond and its application as a heating material in a multi-anvil high-pressure apparatus.

Xie L, Yoneda A, Yoshino T, Yamazaki D, Tsujino N, Higo Y, Tange Y, Irifune T, Shimei T, Ito E.

Rev Sci Instrum. 2017 Sep;88(9):093904. doi: 10.1063/1.4993959.


School mental healthcare services using internet-based cognitive behaviour therapy for young male athletes in Japan.

Sekizaki R, Nemoto T, Tsujino N, Takano C, Yoshida C, Yamaguchi T, Katagiri N, Ono Y, Mizuno M.

Early Interv Psychiatry. 2019 Feb;13(1):79-85. doi: 10.1111/eip.12454. Epub 2017 Jun 14.


Longitudinal study examining abnormal white matter integrity using a tract-specific analysis in individuals with a high risk for psychosis.

Saito J, Hori M, Nemoto T, Katagiri N, Shimoji K, Ito S, Tsujino N, Yamaguchi T, Shiraga N, Aoki S, Mizuno M.

Psychiatry Clin Neurosci. 2017 Aug;71(8):530-541. doi: 10.1111/pcn.12515. Epub 2017 Apr 3.


Stigma toward psychosis and its formulation process: prejudice and discrimination against early stages of schizophrenia.

Baba Y, Nemoto T, Tsujino N, Yamaguchi T, Katagiri N, Mizuno M.

Compr Psychiatry. 2017 Feb;73:181-186. doi: 10.1016/j.comppsych.2016.11.005. Epub 2016 Nov 17.


Mantle dynamics inferred from the crystallographic preferred orientation of bridgmanite.

Tsujino N, Nishihara Y, Yamazaki D, Seto Y, Higo Y, Takahashi E.

Nature. 2016 Nov 3;539(7627):81-84. doi: 10.1038/nature19777. Epub 2016 Oct 17.


Effect of cation substitution on bridgmanite elasticity: A key to interpret seismic anomalies in the lower mantle.

Fukui H, Yoneda A, Nakatsuka A, Tsujino N, Kamada S, Ohtani E, Shatskiy A, Hirao N, Tsutsui S, Uchiyama H, Baron AQ.

Sci Rep. 2016 Sep 19;6:33337. doi: 10.1038/srep33337.


Generation of pressures over 40 GPa using Kawai-type multi-anvil press with tungsten carbide anvils.

Ishii T, Shi L, Huang R, Tsujino N, Druzhbin D, Myhill R, Li Y, Wang L, Yamamoto T, Miyajima N, Kawazoe T, Nishiyama N, Higo Y, Tange Y, Katsura T.

Rev Sci Instrum. 2016 Feb;87(2):024501. doi: 10.1063/1.4941716.


Characteristics of motivation and their impacts on the functional outcomes in patients with schizophrenia.

Tobe M, Nemoto T, Tsujino N, Yamaguchi T, Katagiri N, Fujii C, Mizuno M.

Compr Psychiatry. 2016 Feb;65:103-9. doi: 10.1016/j.comppsych.2015.10.006. Epub 2015 Oct 27.


Sleep as a biological problem: an overview of frontiers in sleep research.

Kanda T, Tsujino N, Kuramoto E, Koyama Y, Susaki EA, Chikahisa S, Funato H.

J Physiol Sci. 2016 Jan;66(1):1-13. doi: 10.1007/s12576-015-0414-3. Epub 2015 Nov 5. Review.


Differential impacts of duration of untreated psychosis (DUP) on cognitive function in first-episode schizophrenia according to mode of onset.

Ito S, Nemoto T, Tsujino N, Ohmuro N, Matsumoto K, Matsuoka H, Tanaka K, Nishiyama S, Suzuki M, Kinoshita H, Ozawa H, Fujita H, Shimodera S, Kishimoto T, Matsumoto K, Hasegawa T, Mizuno M.

Eur Psychiatry. 2015 Nov;30(8):995-1001. doi: 10.1016/j.eurpsy.2015.08.004. Epub 2015 Oct 24.


Differences between subjective experiences and observed behaviors in near-fatal suicide attempters with untreated schizophrenia: a qualitative pilot study.

Yamaguchi T, Fujii C, Nemoto T, Tsujino N, Takeshi K, Mizuno M.

Ann Gen Psychiatry. 2015 Apr 15;14:17. doi: 10.1186/s12991-015-0055-1. eCollection 2015.


A longitudinal study investigating sub-threshold symptoms and white matter changes in individuals with an 'at risk mental state' (ARMS).

Katagiri N, Pantelis C, Nemoto T, Zalesky A, Hori M, Shimoji K, Saito J, Ito S, Dwyer DB, Fukunaga I, Morita K, Tsujino N, Yamaguchi T, Shiraga N, Aoki S, Mizuno M.

Schizophr Res. 2015 Mar;162(1-3):7-13. doi: 10.1016/j.schres.2015.01.002. Epub 2015 Jan 28.


Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice.

Etori K, Saito YC, Tsujino N, Sakurai T.

Front Neurosci. 2014 Jan 31;8:8. doi: 10.3389/fnins.2014.00008. eCollection 2014.


Long-term Efficacy and Tolerability of Perospirone for Young Help-seeking People at Clinical High Risk: a Preliminary Open Trial.

Tsujino N, Nemoto T, Morita K, Katagiri N, Ito S, Mizuno M.

Clin Psychopharmacol Neurosci. 2013 Dec;11(3):132-6. doi: 10.9758/cpn.2013.11.3.132. Epub 2013 Dec 24.


GABAergic neurons in the preoptic area send direct inhibitory projections to orexin neurons.

Saito YC, Tsujino N, Hasegawa E, Akashi K, Abe M, Mieda M, Sakimura K, Sakurai T.

Front Neural Circuits. 2013 Dec 2;7:192. doi: 10.3389/fncir.2013.00192. eCollection 2013.


Chronic alterations in monoaminergic cells in the locus coeruleus in orexin neuron-ablated narcoleptic mice.

Tsujino N, Tsunematsu T, Uchigashima M, Konno K, Yamanaka A, Kobayashi K, Watanabe M, Koyama Y, Sakurai T.

PLoS One. 2013 Jul 29;8(7):e70012. doi: 10.1371/journal.pone.0070012. Print 2013.


Differential roles of orexin receptors in the regulation of sleep/wakefulness.

Mieda M, Tsujino N, Sakurai T.

Front Endocrinol (Lausanne). 2013 May 16;4:57. doi: 10.3389/fendo.2013.00057. eCollection 2013.


[Efforts toward comprehensive early intervention at Early Psychosis Unit "II Bosco"].

Funatogawa T, Nemoto T, Takeshi K, Saito J, Yamaguchi T, Tsujino N, Mizuno M.

Seishin Shinkeigaku Zasshi. 2013;115(2):154-9. Japanese.


Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states.

Furutani N, Hondo M, Kageyama H, Tsujino N, Mieda M, Yanagisawa M, Shioda S, Sakurai T.

PLoS One. 2013 Apr 19;8(4):e62391. doi: 10.1371/journal.pone.0062391. Print 2013.


Role of orexin in modulating arousal, feeding, and motivation.

Tsujino N, Sakurai T.

Front Behav Neurosci. 2013 Apr 18;7:28. doi: 10.3389/fnbeh.2013.00028. eCollection 2013.


[Survey on the actual condition of psychiatrists and psychiatric services in Japan. (Part 2): Change in geographical working area and setting of each psychiatrist].

Inagaki A, Mizuno M, Fujiwara S, Enokido F, Tsujino N, Nemoto Y, Nozaki S, Kojima T.

Seishin Shinkeigaku Zasshi. 2012;114(12):1374-84. Japanese.


[Survey on the actual condition of psychiatrists and psychiatric services in Japan. (Part 1): Basic data on number and distribution of psychiatrists].

Mizuno M, Inagaki A, Fujiwara S, Enokido F, Tsujino N, Nemoto Y, Nozaki S, Kojima T.

Seishin Shinkeigaku Zasshi. 2012;114(12):1359-73. Japanese.


Poor outcome associated with symptomatic deterioration among help-seeking individuals at risk for psychosis: a naturalistic follow-up study.

Morita K, Kobayashi H, Takeshi K, Tsujino N, Nemoto T, Mizuno M.

Early Interv Psychiatry. 2014 Feb;8(1):24-31. doi: 10.1111/eip.12032. Epub 2013 Jan 24.


Clinical practice at a multi-dimensional treatment centre for individuals with early psychosis in Japan.

Nemoto T, Funatogawa T, Takeshi K, Tobe M, Yamaguchi T, Morita K, Katagiri N, Tsujino N, Mizuno M.

East Asian Arch Psychiatry. 2012 Sep;22(3):110-3.


[Circadian rhythm of leptin, orexin and ghrelin].

Tsujino N, Sakurai T.

Nihon Rinsho. 2012 Jul;70(7):1121-5. Japanese.


A single nucleotide polymorphism of the neuropeptide B/W receptor-1 gene influences the evaluation of facial expressions.

Watanabe N, Wada M, Irukayama-Tomobe Y, Ogata Y, Tsujino N, Suzuki M, Furutani N, Sakurai T, Yamamoto M.

PLoS One. 2012;7(4):e35390. doi: 10.1371/journal.pone.0035390. Epub 2012 Apr 24.


Early psychosis in Asia: Insights from Japan.

Mizuno M, Nemoto T, Tsujino N, Funatogawa T, Takeshi K.

Asian J Psychiatr. 2012 Mar;5(1):93-7. doi: 10.1016/j.ajp.2012.02.004. Epub 2012 Mar 3.


Cerebral blood flow changes in very-late-onset schizophrenia-like psychosis with catatonia before and after successful treatment.

Tsujino N, Nemoto T, Yamaguchi T, Katagiri N, Tohgi N, Ikeda R, Shiraga N, Mizumura S, Mizuno M.

Psychiatry Clin Neurosci. 2011 Oct;65(6):600-3. doi: 10.1111/j.1440-1819.2011.02257.x.


Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice.

Sasaki K, Suzuki M, Mieda M, Tsujino N, Roth B, Sakurai T.

PLoS One. 2011;6(5):e20360. doi: 10.1371/journal.pone.0020360. Epub 2011 May 27.


Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory.

Nagata-Kuroiwa R, Furutani N, Hara J, Hondo M, Ishii M, Abe T, Mieda M, Tsujino N, Motoike T, Yanagawa Y, Kuwaki T, Yamamoto M, Yanagisawa M, Sakurai T.

PLoS One. 2011 Feb 24;6(2):e16972. doi: 10.1371/journal.pone.0016972.


The orexin system: roles in sleep/wake regulation.

Sakurai T, Mieda M, Tsujino N.

Ann N Y Acad Sci. 2010 Jul;1200:149-61. doi: 10.1111/j.1749-6632.2010.05513.x. Review.


Activation of bombesin receptor subtype-3 influences activity of orexin neurons by both direct and indirect pathways.

Furutani N, Hondo M, Tsujino N, Sakurai T.

J Mol Neurosci. 2010 Sep;42(1):106-11. doi: 10.1007/s12031-010-9382-5. Epub 2010 May 14.


Dyke-Davidoff-Masson Syndrome Demonstrated by Current MR images. A Case Report.

Hori M, Mizuno M, Katagiri N, Takeshi K, Tsujino N, Araki T, Shiraga N.

Neuroradiol J. 2009 Dec 14;22(5):546-9. Epub 2009 Dec 14.


Stress measurement under high pressure using Kawai-type multi-anvil apparatus combined with synchrotron radiation.

Nishihara Y, Funakoshi K, Higo Y, Terasaki H, Nishiyama N, Kubo T, Shimojuku A, Tsujino N.

J Synchrotron Radiat. 2009 Nov;16(Pt 6):757-61. doi: 10.1107/S0909049509034955. Epub 2009 Sep 15.


Nicorandil ameliorates impulse conduction disturbances during ischemia in isolated arterially perfused canine atria.

Hirose M, Yano S, Nakada T, Horiuchi-Hirose M, Tsujino N, Yamada M.

Int J Cardiol. 2011 Jan 7;146(1):37-43. doi: 10.1016/j.ijcard.2009.06.011. Epub 2009 Jul 1.


Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system.

Tsujino N, Sakurai T.

Pharmacol Rev. 2009 Jun;61(2):162-76. doi: 10.1124/pr.109.001321. Review.


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