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Items: 1 to 50 of 372

1.

Ethanol-Induced Cervical Sympathetic Ganglion Block Applications for Promoting Canine Inferior Alveolar Nerve Regeneration Using an Artificial Nerve.

Shionoya Y, Sunada K, Tsujimoto G, Shigeno K, Nakamura T.

J Vis Exp. 2018 Nov 30;(141). doi: 10.3791/58039.

PMID:
30582606
2.

Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance.

Koshimizu TA, Honda K, Nagaoka-Uozumi S, Ichimura A, Kimura I, Nakaya M, Sakai N, Shibata K, Ushijima K, Fujimura A, Hirasawa A, Kurose H, Tsujimoto G, Tanoue A, Takano Y.

Nat Neurosci. 2018 Jun;21(6):820-833. doi: 10.1038/s41593-018-0144-y. Epub 2018 Apr 30.

PMID:
29713080
3.

The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages.

Nakajima A, Nakatani A, Hasegawa S, Irie J, Ozawa K, Tsujimoto G, Suganami T, Itoh H, Kimura I.

PLoS One. 2017 Jul 10;12(7):e0179696. doi: 10.1371/journal.pone.0179696. eCollection 2017.

4.

Regeneration of gingival tissue using in situ tissue engineering with collagen scaffold.

Hatayama T, Nakada A, Nakamura H, Mariko W, Tsujimoto G, Nakamura T.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Oct;124(4):348-354.e1. doi: 10.1016/j.oooo.2017.05.471. Epub 2017 May 11.

PMID:
28690084
5.

Effect of cervical sympathetic ganglionectomy on facial nerve reconstruction using polyglycolic acid-collagen tubes.

Tsujimoto G, Sunada K, Nakamura T.

Brain Res. 2017 Aug 15;1669:79-88. doi: 10.1016/j.brainres.2017.05.028. Epub 2017 May 31.

PMID:
28578166
6.

Effects of arachidonic acid on FFA4 receptor: Signaling, phosphorylation and internalization.

Villegas-Comonfort S, Takei Y, Tsujimoto G, Hirasawa A, García-Sáinz JA.

Prostaglandins Leukot Essent Fatty Acids. 2017 Feb;117:1-10. doi: 10.1016/j.plefa.2017.01.013. Epub 2017 Jan 26.

PMID:
28237082
7.

Agonists and protein kinase C-activation induce phosphorylation and internalization of FFA1 receptors.

Sosa-Alvarado C, Hernández-Méndez A, Romero-Ávila MT, Sánchez-Reyes OB, Takei Y, Tsujimoto G, Hirasawa A, García-Sáinz JA.

Eur J Pharmacol. 2015 Dec 5;768:108-15. doi: 10.1016/j.ejphar.2015.10.038. Epub 2015 Oct 23.

PMID:
26526350
8.

The Effects of a Selective CK2 Inhibitor on Anti-glomerular Basement Membrane Glomerulonephritis in Rats.

Shi J, Liu N, Xiao Y, Takei Y, Yasue M, Suzuki Y, Hou Z, Ohno H, Yamada M, Fuchi N, Oshida K, Miyamoto Y, Tsujimoto G, Hirasawa A.

Biol Pharm Bull. 2015;38(9):1345-51. doi: 10.1248/bpb.b15-00195.

9.

Effects of a Tricaprylin Emulsion on Anti-glomerular Basement Membrane Glomerulonephritis in Rats: In Vivo and in Silico Studies.

Liu N, Shi J, Xiao Y, Yasue M, Takei Y, Sanefuji H, Tsujimoto G, Hirasawa A.

Biol Pharm Bull. 2015;38(8):1175-84. doi: 10.1248/bpb.b15-00124.

10.

Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening.

Nakanishi I, Murata K, Nagata N, Kurono M, Kinoshita T, Yasue M, Miyazaki T, Takei Y, Nakamura S, Sakurai A, Iwamoto N, Nishiwaki K, Nakaniwa T, Sekiguchi Y, Hirasawa A, Tsujimoto G, Kitaura K.

Eur J Med Chem. 2015;96:396-404. doi: 10.1016/j.ejmech.2015.04.032. Epub 2015 Apr 15.

PMID:
25912672
11.

The oral lipid sensor GPR120 is not indispensable for the orosensory detection of dietary lipids in mice.

Ancel D, Bernard A, Subramaniam S, Hirasawa A, Tsujimoto G, Hashimoto T, Passilly-Degrace P, Khan NA, Besnard P.

J Lipid Res. 2015 Feb;56(2):369-78. doi: 10.1194/jlr.M055202. Epub 2014 Dec 8.

12.

The SCFA Receptor GPR43 and Energy Metabolism.

Kimura I, Inoue D, Hirano K, Tsujimoto G.

Front Endocrinol (Lausanne). 2014 Jun 5;5:85. doi: 10.3389/fendo.2014.00085. eCollection 2014. Review.

13.

Role of free fatty acid receptors in the regulation of energy metabolism.

Hara T, Kashihara D, Ichimura A, Kimura I, Tsujimoto G, Hirasawa A.

Biochim Biophys Acta. 2014 Sep;1841(9):1292-300. doi: 10.1016/j.bbalip.2014.06.002. Epub 2014 Jun 10. Review.

PMID:
24923869
14.

Regulation of Energy Homeostasis by GPR41.

Inoue D, Tsujimoto G, Kimura I.

Front Endocrinol (Lausanne). 2014 May 26;5:81. doi: 10.3389/fendo.2014.00081. eCollection 2014. Review.

15.

Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation.

Sánchez-Reyes OB, Romero-Ávila MT, Castillo-Badillo JA, Takei Y, Hirasawa A, Tsujimoto G, Villalobos-Molina R, García-Sáinz JA.

Eur J Pharmacol. 2014 Jan 15;723:368-74. doi: 10.1016/j.ejphar.2013.11.003. Epub 2013 Nov 12.

PMID:
24239485
16.

Mice genetically deficient in vasopressin V1a and V1b receptors are resistant to jet lag.

Yamaguchi Y, Suzuki T, Mizoro Y, Kori H, Okada K, Chen Y, Fustin JM, Yamazaki F, Mizuguchi N, Zhang J, Dong X, Tsujimoto G, Okuno Y, Doi M, Okamura H.

Science. 2013 Oct 4;342(6154):85-90. doi: 10.1126/science.1238599.

17.

Voluntary locomotion linked with cerebral activation is mediated by vasopressin V1a receptors in free-moving mice.

Masuki S, Sumiyoshi E, Koshimizu TA, Qian J, Higuchi K, Tsujimoto G, Nose H.

J Physiol. 2013 Jul 15;591(14):3651-65. doi: 10.1113/jphysiol.2013.251876. Epub 2013 May 13.

18.

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.

Kimura I, Ozawa K, Inoue D, Imamura T, Kimura K, Maeda T, Terasawa K, Kashihara D, Hirano K, Tani T, Takahashi T, Miyauchi S, Shioi G, Inoue H, Tsujimoto G.

Nat Commun. 2013;4:1829. doi: 10.1038/ncomms2852.

19.

Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors.

Hou Z, Oishi S, Suzuki Y, Kure T, Nakanishi I, Hirasawa A, Tsujimoto G, Ohno H, Fujii N.

Org Biomol Chem. 2013 May 28;11(20):3288-96. doi: 10.1039/c3ob40223a.

PMID:
23535832
20.

[Physiological functions of fatty acid receptors and their therapeutic potential].

Hara T, Hirasawa A, Ichimura A, Kimura I, Tsujimoto G.

Nihon Yakurigaku Zasshi. 2012 Dec;140(6):275-9. Review. Japanese. No abstract available.

PMID:
23229634
21.

Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development.

Yamauchi J, Miyamoto Y, Torii T, Takashima S, Kondo K, Kawahara K, Nemoto N, Chan JR, Tsujimoto G, Tanoue A.

Sci Signal. 2012 Sep 25;5(243):ra69.

22.

Rapid quantitative profiling of N-glycan by the glycan-labeling method using 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid.

Kaneshiro K, Watanabe M, Terasawa K, Uchimura H, Fukuyama Y, Iwamoto S, Sato TA, Shimizu K, Tsujimoto G, Tanaka K.

Anal Chem. 2012 Aug 21;84(16):7146-51. doi: 10.1021/ac301484f. Epub 2012 Aug 2.

PMID:
22830976
23.

Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation.

Inoue D, Kimura I, Wakabayashi M, Tsumoto H, Ozawa K, Hara T, Takei Y, Hirasawa A, Ishihama Y, Tsujimoto G.

FEBS Lett. 2012 May 21;586(10):1547-54. doi: 10.1016/j.febslet.2012.04.021. Epub 2012 Apr 21.

24.

FFA1-selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models.

Takeuchi M, Hirasawa A, Hara T, Kimura I, Hirano T, Suzuki T, Miyata N, Awaji T, Ishiguro M, Tsujimoto G.

Br J Pharmacol. 2013 Apr;168(7):1570-83. doi: 10.1111/j.1476-5381.2012.02052.x.

25.

Proteomic analysis of the role of S-nitrosoglutathione reductase in lipopolysaccharide-challenged mice.

Ozawa K, Tsumoto H, Wei W, Tang CH, Komatsubara AT, Kawafune H, Shimizu K, Liu L, Tsujimoto G.

Proteomics. 2012 Jun;12(12):2024-35. doi: 10.1002/pmic.201100666.

26.

Design and synthesis of a novel class of CK2 inhibitors: application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles.

Suzuki Y, Oishi S, Takei Y, Yasue M, Misu R, Naoe S, Hou Z, Kure T, Nakanishi I, Ohno H, Hirasawa A, Tsujimoto G, Fujii N.

Org Biomol Chem. 2012 Jul 7;10(25):4907-15. doi: 10.1039/c2ob25298h. Epub 2012 May 21.

PMID:
22610034
27.

Development and application of fluorescent SDF-1 derivatives.

Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Kodama E, Matsuoka M, Fujii N.

Future Med Chem. 2012 May;4(7):837-44. doi: 10.4155/fmc.12.31.

PMID:
22571609
28.

Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists.

Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Navenot JM, Peiper SC, Fujii N.

Bioconjug Chem. 2012 Jun 20;23(6):1259-65. doi: 10.1021/bc300084h. Epub 2012 May 9.

PMID:
22486464
29.

Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells.

Ichikawa T, Sato F, Terasawa K, Tsuchiya S, Toi M, Tsujimoto G, Shimizu K.

PLoS One. 2012;7(2):e31422. doi: 10.1371/journal.pone.0031422. Epub 2012 Feb 27.

30.

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.

Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Lévy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P.

Nature. 2012 Feb 19;483(7389):350-4. doi: 10.1038/nature10798.

PMID:
22343897
31.

Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds.

Hou Z, Nakanishi I, Kinoshita T, Takei Y, Yasue M, Misu R, Suzuki Y, Nakamura S, Kure T, Ohno H, Murata K, Kitaura K, Hirasawa A, Tsujimoto G, Oishi S, Fujii N.

J Med Chem. 2012 Mar 22;55(6):2899-903. doi: 10.1021/jm2015167. Epub 2012 Mar 7.

PMID:
22339433
32.

[Free fatty acid receptors and their physiological role in metabolic regulation].

Hirasawa A, Hara T, Ichimura A, Tsujimoto G.

Yakugaku Zasshi. 2011;131(12):1683-9. Review. Japanese.

33.

The roles of V1a vasopressin receptors in blood pressure homeostasis: a review of studies on V1a receptor knockout mice.

Fujiwara Y, Tanoue A, Tsujimoto G, Koshimizu TA.

Clin Exp Nephrol. 2012 Feb;16(1):30-4. doi: 10.1007/s10157-011-0497-y. Epub 2011 Nov 1. Review.

PMID:
22038263
34.

α(1D)-Adrenoceptor regulates the vasopressor action of α(1A)-adrenoceptor in mesenteric vascular bed of α(1D)-adrenoceptor knockout mice.

Martínez-Salas SG, Campos-Peralta JM, Pardo JP, Hernández-Muñoz R, Ibarra M, Tanoue A, Tsujimoto G, Villalobos-Molina R.

Auton Autacoid Pharmacol. 2011 Jul-Oct;31(3-4):64-71. doi: 10.1111/j.1474-8673.2011.00468.x.

PMID:
21951586
35.

Angiotensin II modifies the expression of α(1)-adrenoceptors in aorta smooth muscle cells of α(1D)-adrenoceptor knockout mice.

Lázaro-Suárez ML, Gómez-Zamudio JH, Delgado-Buenrostro NL, Tanoue A, Tsujimoto G, Villalobos-Molina R.

Auton Autacoid Pharmacol. 2011 Jul-Oct;31(3-4):57-63. doi: 10.1111/j.1474-8673.2011.00467.x.

PMID:
21951585
36.

Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation.

Takai A, Marusawa H, Minaki Y, Watanabe T, Nakase H, Kinoshita K, Tsujimoto G, Chiba T.

Oncogene. 2012 Mar 29;31(13):1733-42. doi: 10.1038/onc.2011.352. Epub 2011 Aug 15.

37.

Synthetic Pre-miRNA-Based shRNA as Potent RNAi Triggers.

Terasawa K, Shimizu K, Tsujimoto G.

J Nucleic Acids. 2011;2011:131579. doi: 10.4061/2011/131579. Epub 2011 Jul 12.

38.

A detailed thermodynamic profile of cyclopentyl and isopropyl derivatives binding to CK2 kinase.

Kinoshita T, Sekiguchi Y, Fukada H, Nakaniwa T, Tada T, Nakamura S, Kitaura K, Ohno H, Suzuki Y, Hirasawa A, Nakanishi I, Tsujimoto G.

Mol Cell Biochem. 2011 Oct;356(1-2):97-105. doi: 10.1007/s11010-011-0960-9. Epub 2011 Jul 7.

PMID:
21735094
39.

Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders.

Hara T, Hirasawa A, Ichimura A, Kimura I, Tsujimoto G.

J Pharm Sci. 2011 Sep;100(9):3594-601. doi: 10.1002/jps.22639. Epub 2011 May 25. Review.

PMID:
21618241
40.

Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus.

Doi M, Ishida A, Miyake A, Sato M, Komatsu R, Yamazaki F, Kimura I, Tsuchiya S, Kori H, Seo K, Yamaguchi Y, Matsuo M, Fustin JM, Tanaka R, Santo Y, Yamada H, Takahashi Y, Araki M, Nakao K, Aizawa S, Kobayashi M, Obrietan K, Tsujimoto G, Okamura H.

Nat Commun. 2011;2:327. doi: 10.1038/ncomms1316.

41.

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41).

Kimura I, Inoue D, Maeda T, Hara T, Ichimura A, Miyauchi S, Kobayashi M, Hirasawa A, Tsujimoto G.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):8030-5. doi: 10.1073/pnas.1016088108. Epub 2011 Apr 25.

42.

MicroRNAs, regulatory networks and diseases: an overview.

Tsujimoto G.

FEBS J. 2011 May;278(10):1597. doi: 10.1111/j.1742-4658.2011.08088.x. Epub 2011 Mar 30. No abstract available.

43.

miRNAs and regulation of cell signaling.

Ichimura A, Ruike Y, Terasawa K, Tsujimoto G.

FEBS J. 2011 May;278(10):1610-8. doi: 10.1111/j.1742-4658.2011.08087.x. Epub 2011 Mar 30. Review.

44.

Analysis of multiple compound-protein interactions reveals novel bioactive molecules.

Yabuuchi H, Niijima S, Takematsu H, Ida T, Hirokawa T, Hara T, Ogawa T, Minowa Y, Tsujimoto G, Okuno Y.

Mol Syst Biol. 2011 Mar 1;7:472. doi: 10.1038/msb.2011.5.

45.

MicroRNA profile predicts recurrence after resection in patients with hepatocellular carcinoma within the Milan Criteria.

Sato F, Hatano E, Kitamura K, Myomoto A, Fujiwara T, Takizawa S, Tsuchiya S, Tsujimoto G, Uemoto S, Shimizu K.

PLoS One. 2011 Jan 27;6(1):e16435. doi: 10.1371/journal.pone.0016435.

46.

MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma.

Imanaka Y, Tsuchiya S, Sato F, Shimada Y, Shimizu K, Tsujimoto G.

J Hum Genet. 2011 Apr;56(4):270-6. doi: 10.1038/jhg.2011.1. Epub 2011 Feb 3.

PMID:
21289630
47.

Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands.

Oishi S, Misu R, Tomita K, Setsuda S, Masuda R, Ohno H, Naniwa Y, Ieda N, Inoue N, Ohkura S, Uenoyama Y, Tsukamura H, Maeda K, Hirasawa A, Tsujimoto G, Fujii N.

ACS Med Chem Lett. 2010 Oct 25;2(1):53-7. doi: 10.1021/ml1002053. eCollection 2011 Jan 13.

48.

MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1).

Tsuchiya S, Fujiwara T, Sato F, Shimada Y, Tanaka E, Sakai Y, Shimizu K, Tsujimoto G.

J Biol Chem. 2011 Jan 7;286(1):420-8. doi: 10.1074/jbc.M110.170852. Epub 2010 Nov 2.

49.

[Overview and future vision of drug discovery based on the genomic science].

Tsujimoto G.

Nihon Rinsho. 2010 Aug;68 Suppl 8:670-5. Review. Japanese. No abstract available.

PMID:
20979314
50.

Structure-activity relationships of GPR120 agonists based on a docking simulation.

Sun Q, Hirasawa A, Hara T, Kimura I, Adachi T, Awaji T, Ishiguro M, Suzuki T, Miyata N, Tsujimoto G.

Mol Pharmacol. 2010 Nov;78(5):804-10. doi: 10.1124/mol.110.066324. Epub 2010 Aug 4.

PMID:
20685848

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