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Items: 1 to 50 of 198


Progression of diabetic kidney disease and trajectory of kidney function decline in Chinese patients with Type 2 diabetes.

Jiang G, Luk AOY, Tam CHT, Xie F, Carstensen B, Lau ESH, Lim CKP, Lee HM, Ng ACW, Ng MCY, Ozaki R, Kong APS, Chow CC, Yang X, Lan HY, Tsui SKW, Fan X, Szeto CC, So WY, Chan JCN, Ma RCW; Hong Kong Diabetes Register TRS Study Group.

Kidney Int. 2019 Jan;95(1):178-187. doi: 10.1016/j.kint.2018.08.026. Epub 2018 Nov 8.


Preventive sublingual immunotherapy with House Dust Mite extract modulates epitope diversity in pre-school children.

Ponce M, Schroeder F, Bannert C, Schmidthaler K, Hansen CS, Lindholm Bøgh K, Soldo R, Tsui SK, Weinhäusel A, Szépfalusi Z, Eiwegger T.

Allergy. 2018 Nov 5. doi: 10.1111/all.13658. [Epub ahead of print]


Systematic Comparison of Bacterial Colonization of Endometrial Tissue and Fluid Samples in Recurrent Miscarriage Patients: Implications for Future Endometrial Microbiome Studies.

Liu Y, Wong KK, Ko EY, Chen X, Huang J, Tsui SK, Li TC, Chim SS.

Clin Chem. 2018 Dec;64(12):1743-1752. doi: 10.1373/clinchem.2018.289306. Epub 2018 Sep 20.


Turmeric extract, with absorbable curcumin, has potent anti-metastatic effect in vitro and in vivo.

Li M, Yue GG, Tsui SK, Fung KP, Lau CB.

Phytomedicine. 2018 Jul 15;46:131-141. doi: 10.1016/j.phymed.2018.03.065. Epub 2018 Apr 3.


Regulation of TLR4 in silica-induced inflammation: An underlying mechanism of silicosis.

Chan JYW, Tsui JCC, Law PTW, So WKW, Leung DYP, Sham MMK, Tsui SKW, Chan CWH.

Int J Med Sci. 2018 Jun 14;15(10):986-991. doi: 10.7150/ijms.24715. eCollection 2018.


Whole genome sequencing data of 1110 Mycobacterium tuberculosis isolates identifies insertions and deletions associated with drug resistance.

Zeng X, Kwok JS, Yang KY, Leung KS, Shi M, Yang Z, Yam WC, Tsui SK.

BMC Genomics. 2018 May 16;19(1):365. doi: 10.1186/s12864-018-4734-6.


Functional Annotation of Proteins Encoded by the Minimal Bacterial Genome Based on Secondary Structure Element Alignment.

Yang Z, Tsui SK.

J Proteome Res. 2018 Jul 6;17(7):2511-2520. doi: 10.1021/acs.jproteome.8b00262. Epub 2018 May 24.


Adverse Effects of Azathioprine in a Child and Her Mother with Eczema.

Hon KL, Chang M, Chong SC, Yuen YP, Tsui SKW.

Indian J Pediatr. 2018 Oct;85(10):918-919. doi: 10.1007/s12098-018-2687-z. Epub 2018 May 12. No abstract available.


Differential regulation of the pro-inflammatory biomarker, YKL-40/CHI3L1, by PTEN/Phosphoinositide 3-kinase and JAK2/STAT3 pathways in glioblastoma.

Wang Y, Wong CW, Yan M, Li L, Liu T, Or PM, Tsui SK, Waye MM, Chan AM.

Cancer Lett. 2018 Aug 10;429:54-65. doi: 10.1016/j.canlet.2018.04.040. Epub 2018 May 3.


Drugs for targeted therapies of Alzheimer's disease.

Tam C, Wong JH, Ng TB, Tsui SK, Zuo T.

Curr Med Chem. 2018 Apr 30. doi: 10.2174/0929867325666180430150940. [Epub ahead of print]


Functional roles of eriocalyxin B in zebrafish revealed by transcriptome analysis.

Zhou X, Cao CY, Wan AT, Yue GG, Kwok FH, Fung KP, Sun H, Lau CB, Puno PT, Tsui SK.

Mol Omics. 2018 Jun 12;14(3):156-169. doi: 10.1039/c7mo00125h.


Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments.

Qin H, Lo NW, Loo JF, Lin X, Yim AK, Tsui SK, Lau TC, Ip M, Chan TF.

Sci Rep. 2018 Feb 23;8(1):3515. doi: 10.1038/s41598-018-21841-9.


Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.

Li M, Yue GG, Song LH, Huang MB, Lee JK, Tsui SK, Fung KP, Tan NH, Lau CB.

Biochem Pharmacol. 2018 Apr;150:191-201. doi: 10.1016/j.bcp.2018.02.017. Epub 2018 Feb 16.


Hypermethylation of NF-κB-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis.

Ng PKS, Lau CPY, Lam EKY, Li SSK, Lui VWY, Yeo W, Ng YK, Lai PBS, Tsui SKW.

Dig Dis Sci. 2018 Mar;63(3):676-686. doi: 10.1007/s10620-018-4929-3. Epub 2018 Jan 20.


High-quality assembly of Dermatophagoides pteronyssinus genome and transcriptome reveals a wide range of novel allergens.

Liu XY, Yang KY, Wang MQ, Kwok JS, Zeng X, Yang Z, Xiao XJ, Lau CP, Li Y, Huang ZM, Ba JG, Yim AK, Ouyang CY, Ngai SM, Chan TF, Leung EL, Liu L, Liu ZG, Tsui SK.

J Allergy Clin Immunol. 2018 Jun;141(6):2268-2271.e8. doi: 10.1016/j.jaci.2017.11.038. Epub 2018 Jan 2. No abstract available.


RNA-Seq revealed ATF3-regulated inflammation induced by silica.

Chan JYW, Tsui JCC, Law PTW, So WKW, Leung DYP, Sham MMK, Tsui SKW, Chan CWH.

Toxicology. 2018 Jan 15;393:34-41. doi: 10.1016/j.tox.2017.11.001. Epub 2017 Nov 2.


Structural basis of the PE-PPE protein interaction in Mycobacterium tuberculosis.

Chen X, Cheng HF, Zhou J, Chan CY, Lau KF, Tsui SK, Au SW.

J Biol Chem. 2017 Oct 13;292(41):16880-16890. doi: 10.1074/jbc.M117.802645. Epub 2017 Aug 23.


Systematic Selection of Reference Genes for the Normalization of Circulating RNA Transcripts in Pregnant Women Based on RNA-Seq Data.

Chim SSC, Wong KKW, Chung CYL, Lam SKW, Kwok JSL, Lai CY, Cheng YKY, Hui ASY, Meng M, Chan OK, Tsui SKW, Lee KY, Chan TF, Leung TY.

Int J Mol Sci. 2017 Aug 4;18(8). pii: E1709. doi: 10.3390/ijms18081709.


Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.

Zhou X, Yue GG, Chan AM, Tsui SK, Fung KP, Sun H, Pu J, Lau CB.

Biochem Pharmacol. 2017 Oct 15;142:58-70. doi: 10.1016/j.bcp.2017.06.133. Epub 2017 Jun 30.


Profiling of the silica-induced molecular events in lung epithelial cells using the RNA-Seq approach.

Chan JYW, Tsui JCC, Law PTW, So WKW, Leung DYP, Sham MMK, Tsui SKW, Chan CWH.

J Appl Toxicol. 2017 Oct;37(10):1162-1173. doi: 10.1002/jat.3471. Epub 2017 Apr 20.


Correction: Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells.

Zhang Y, Kwok JS, Choi PW, Liu M, Yang J, Singh M, Ng SK, Welch WR, Muto MG, Tsui SK, Sugrue SP, Berkowitz RS, Ng SW.

Oncotarget. 2017 Feb 14;8(7):12533. doi: 10.18632/oncotarget.15321. No abstract available.


Elaborating the Role of Natural Products on the Regulation of Autophagy and their Potentials in Breast Cancer Therapy.

Zhou X, Yue GG, Tsui SK, Pu J, Fung KP, Lau CB.

Curr Cancer Drug Targets. 2018;18(3):239-255. doi: 10.2174/1568009617666170330124819.


Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species.

Li M, Song LH, Yue GG, Lee JK, Zhao LM, Li L, Zhou X, Tsui SK, Ng SS, Fung KP, Tan NH, Lau CB.

Sci Rep. 2017 Feb 9;7:42176. doi: 10.1038/srep42176.


Resequencing three candidate genes discovers seven potentially deleterious variants susceptibility to major depressive disorder and suicide attempts in Chinese.

Rao S, Leung CS, Lam MH, Wing YK, Waye MM, Tsui SK.

Gene. 2017 Mar 1;603:34-41. doi: 10.1016/j.gene.2016.12.006. Epub 2016 Dec 10.


Metagenomics of tuberculosis infection in Hong Kong.

Lam WY, Cheung MK, Fung WY, Law PT, Kam KM, Au CH, Nong WY, Hwang D, Chan RC, Kwan HS, Tsui SK.

Hong Kong Med J. 2016 Dec;22 Suppl 7(6):15-17. No abstract available.


Genome-Wide Transcriptome Profiling of the Neoplastic Giant Cell Tumor of Bone Stromal Cells by RNA Sequencing.

Lau CP, Kwok JS, Tsui JC, Huang L, Yang KY, Tsui SK, Kumta SM.

J Cell Biochem. 2017 Jun;118(6):1349-1360. doi: 10.1002/jcb.25792. Epub 2017 Jan 10.


Differential expression of filamin B splice variants in giant cell tumor cells.

Tsui JC, Lau CP, Cheung AC, Wong KC, Huang L, Tsui SK, Kumta SM.

Oncol Rep. 2016 Dec;36(6):3181-3187. doi: 10.3892/or.2016.5197. Epub 2016 Oct 24.


Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling.

Zhou X, Yue GG, Liu M, Zuo Z, Lee JK, Li M, Tsui SK, Fung KP, Sun H, Pu J, Lau CB.

Oncotarget. 2016 Dec 13;7(50):82820-82835. doi: 10.18632/oncotarget.12652.


Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes.

Li JW, Lee HM, Wang Y, Tong AH, Yip KY, Tsui SK, Lok S, Ozaki R, Luk AO, Kong AP, So WY, Ma RC, Chan JC, Chan TF.

Sci Rep. 2016 Oct 18;6:35228. doi: 10.1038/srep35228.


Immune competence assessment in marine medaka (Orzyias melastigma)-a holistic approach for immunotoxicology.

Ye RR, Peterson DR, Seemann F, Kitamura SI, Lee JS, Lau TCK, Tsui SKW, Au DWT.

Environ Sci Pollut Res Int. 2017 Dec;24(36):27687-27701. doi: 10.1007/s11356-016-7208-x. Epub 2016 Jul 29.


Environmental Factors Associated with Altered Gut Microbiota in Children with Eczema: A Systematic Review.

Chan CW, Wong RS, Law PT, Wong CL, Tsui SK, Tang WP, Sit JW.

Int J Mol Sci. 2016 Jul 16;17(7). pii: E1147. doi: 10.3390/ijms17071147. Review.


Genetic Modification of Human Pancreatic Progenitor Cells Through Modified mRNA.

Lu S, Chow CC, Zhou J, Leung PS, Tsui SK, Lui KO.

Methods Mol Biol. 2016;1428:307-17. doi: 10.1007/978-1-4939-3625-0_21.


Phylogenetic and Structural Significance of Dihydrofolate Synthase (folC) Mutations in Drug-Resistant Mycobacterium tuberculosis.

Cheng VW, Leung KS, Kwok JS, Leung RK, Yang KY, Chan RC, Kam KM, Tsui SK.

Microb Drug Resist. 2016 Oct;22(7):545-551. Epub 2016 Apr 15.


Transcriptome analysis of different developmental stages of amphioxus reveals dynamic changes of distinct classes of genes during development.

Yang KY, Chen Y, Zhang Z, Ng PK, Zhou WJ, Zhang Y, Liu M, Chen J, Mao B, Tsui SK.

Sci Rep. 2016 Mar 16;6:23195. doi: 10.1038/srep23195.


The Utilization of the Immune System in Lung Cancer Treatment: Beyond Chemotherapy.

Chan CW, Tsui SK, Law BM, So WK, Tang FW, Wong CL.

Int J Mol Sci. 2016 Feb 25;17(3):286. doi: 10.3390/ijms17030286. Review.


Characterisation of novel anti-HIV/tuberculosis natural product analogues.

Chen ZW, Liu G, Lu XF, Liu L, Zhang X, Lau TC, Tsui SK, Kang YX, Zheng PR, Zheng BJ.

Hong Kong Med J. 2015 Dec;21 Suppl 7:S14-7. No abstract available.


Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells.

Zhang Y, Kwok JS, Choi PW, Liu M, Yang J, Singh M, Ng SK, Welch WR, Muto MG, Tsui SK, Sugrue SP, Berkowitz RS, Ng SW.

Oncotarget. 2016 Mar 8;7(10):11397-411. doi: 10.18632/oncotarget.7242. Erratum in: Oncotarget. 2017 Feb 14;8(7):12533.


Genetic and clinical variables identify predictors for chronic kidney disease in type 2 diabetes.

Jiang G, Hu C, Tam CH, Lau ES, Wang Y, Luk AO, Yang X, Kong AP, Ho JS, Lam VK, Lee HM, Wang J, Zhang R, Tsui SK, Ng MC, Szeto CC, Jia W, Fan X, So WY, Chan JC, Ma RC.

Kidney Int. 2016 Feb;89(2):411-20. doi: 10.1016/j.kint.2015.09.001. Epub 2016 Jan 6.


Genome-wide analysis of DNA methylation associated with HIV infection based on a pair of monozygotic twins.

Zhang Y, Li SK, Tsui SK.

Genom Data. 2015 Jul 30;6:12-5. doi: 10.1016/j.gdata.2015.07.024. eCollection 2015 Dec.


Metagenomics: A New Way to Illustrate the Crosstalk between Infectious Diseases and Host Microbiome.

Zhang Y, Lun CY, Tsui SK.

Int J Mol Sci. 2015 Nov 3;16(11):26263-79. doi: 10.3390/ijms161125957. Review.


Eczema susceptibility and composition of faecal microbiota at 4 weeks of age: a pilot study in Chinese infants.

Tang MF, Sy HY, Kwok JS, Tam WH, Hon KL, Tung CK, Wong GW, Tsui SK, Leung TF.

Br J Dermatol. 2016 Apr;174(4):898-900. doi: 10.1111/bjd.14205. Epub 2016 Jan 6. No abstract available.


A mouse model of luciferase-transfected stromal cells of giant cell tumor of bone.

Lau CP, Wong KC, Huang L, Li G, Tsui SK, Kumta SM.

Connect Tissue Res. 2015 Nov;56(6):493-503. doi: 10.3109/03008207.2015.1075519. Epub 2015 Sep 1.


Identification of a non-coding KLF4 transcript generated from intron retention and downregulated in human hepatocellular carcinoma.

Zhou J, Lai PB, Tsui SK.

Int J Oncol. 2015 Oct;47(4):1554-62. doi: 10.3892/ijo.2015.3104. Epub 2015 Jul 24.


The FHL2 regulation in the transcriptional circuitry of human cancers.

Cao CY, Mok SW, Cheng VW, Tsui SK.

Gene. 2015 Nov 1;572(1):1-7. doi: 10.1016/j.gene.2015.07.043. Epub 2015 Jul 26. Review.


Molecular changes in endometriosis-associated ovarian clear cell carcinoma.

Worley MJ Jr, Liu S, Hua Y, Kwok JS, Samuel A, Hou L, Shoni M, Lu S, Sandberg EM, Keryan A, Wu D, Ng SK, Kuo WP, Parra-Herran CE, Tsui SK, Welch W, Crum C, Berkowitz RS, Ng SW.

Eur J Cancer. 2015 Sep;51(13):1831-42. doi: 10.1016/j.ejca.2015.05.011. Epub 2015 Jun 6.


Draft Genome Sequence of Catabacter hongkongensis Type Strain HKU16T, Isolated from a Patient with Bacteremia and Intestinal Obstruction.

Lau SK, Teng JL, Huang Y, Curreem SO, Tsui SK, Woo PC.

Genome Announc. 2015 May 21;3(3). pii: e00531-15. doi: 10.1128/genomeA.00531-15.


Draft Genome Sequence of Extensively Drug-Resistant Acinetobacter baumannii Strain CUAB1 from a Patient in Hong Kong, China.

Yim AK, Kwok JS, Yu AC, Leung AK, Lau HH, Chan TF, Ip M, Tsui SK.

Genome Announc. 2015 May 14;3(3). pii: e00442-15. doi: 10.1128/genomeA.00442-15.


MiR-25 suppresses 3T3-L1 adipogenesis by directly targeting KLF4 and C/EBPα.

Liang WC, Wang Y, Liang PP, Pan XQ, Fu WM, Yeung VS, Lu YF, Wan DC, Tsui SK, Tsang SY, Ma WB, Zhang JF, Waye MM.

J Cell Biochem. 2015 Nov;116(11):2658-66. doi: 10.1002/jcb.25214.


Transcriptome analysis of leaves, roots and flowers of Panax notoginseng identifies genes involved in ginsenoside and alkaloid biosynthesis.

Liu MH, Yang BR, Cheung WF, Yang KY, Zhou HF, Kwok JS, Liu GC, Li XF, Zhong S, Lee SM, Tsui SK.

BMC Genomics. 2015 Apr 3;16:265. doi: 10.1186/s12864-015-1477-5.


Heat shock proteins IbpA and IbpB are required for NlpI-participated cell division in Escherichia coli.

Tao J, Sang Y, Teng Q, Ni J, Yang Y, Tsui SK, Yao YF.

Front Microbiol. 2015 Feb 4;6:51. doi: 10.3389/fmicb.2015.00051. eCollection 2015.

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