Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41


Alzheimer's disease: insights for risk evaluation and prevention in the Chinese population and the need for a comprehensive programme in Hong Kong/China.

Yee A, Tsui NB, Chang YN, Au CS, Fok M, Lau LT, Chung T, Chung G, Kwan RY, Leung AY, Lau JY, Dai DL.

Hong Kong Med J. 2018 Oct;24(5):492-500. doi: 10.12809/hkmj187244. Review.


Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.

Tsui NBY, Cheng G, Chung T, Lam CWK, Yee A, Chung PKC, Kwan TK, Ko E, He D, Wong WT, Lau JYN, Lau LT, Fok M.

Sci Rep. 2018 Jan 30;8(1):1853. doi: 10.1038/s41598-017-19017-y.


Novel structural co-expression analysis linking the NPM1-associated ribosomal biogenesis network to chronic myelogenous leukemia.

Chan LW, Lin X, Yung G, Lui T, Chiu YM, Wang F, Tsui NB, Cho WC, Yip SP, Siu PM, Wong SC, Yung BY.

Sci Rep. 2015 Jul 24;5:10973. doi: 10.1038/srep10973.


Current and future molecular diagnostics in non-small-cell lung cancer.

Li CM, Chu WY, Wong DL, Tsang HF, Tsui NB, Chan CM, Xue VW, Siu PM, Yung BY, Chan LW, Wong SC.

Expert Rev Mol Diagn. 2015;15(8):1061-74. doi: 10.1586/14737159.2015.1063420. Epub 2015 Jul 7. Review.


DECODE: an integrated differential co-expression and differential expression analysis of gene expression data.

Lui TW, Tsui NB, Chan LW, Wong CS, Siu PM, Yung BY.

BMC Bioinformatics. 2015 May 31;16:182. doi: 10.1186/s12859-015-0582-4.


Coexpression Pattern Analysis of NPM1-Associated Genes in Chronic Myelogenous Leukemia.

Wang F, Chan LW, Tsui NB, Wong SC, Siu PM, Yip SP, Yung BY.

Biomed Res Int. 2015;2015:610595. doi: 10.1155/2015/610595. Epub 2015 Apr 15.


Gene network exploration of crosstalk between apoptosis and autophagy in chronic myelogenous leukemia.

Wang F, Cho WC, Chan LW, Wong SC, Tsui NB, Siu PM, Yip SP, Yung BY.

Biomed Res Int. 2015;2015:459840. doi: 10.1155/2015/459840. Epub 2015 Mar 3.


Novel approach for coexpression analysis of E2F1-3 and MYC target genes in chronic myelogenous leukemia.

Wang F, Chan LW, Cho WC, Tang P, Yu J, Shyu CR, Tsui NB, Wong SC, Siu PM, Yip SP, Yung BY.

Biomed Res Int. 2014;2014:439840. doi: 10.1155/2014/439840. Epub 2014 Aug 10.


Current and future molecular diagnostics in colorectal cancer and colorectal adenoma.

Tsang AH, Cheng KH, Wong AS, Ng SS, Ma BB, Chan CM, Tsui NB, Chan LW, Yung BY, Wong SC.

World J Gastroenterol. 2014 Apr 14;20(14):3847-57. doi: 10.3748/wjg.v20.i14.3847. Review.


Maternal plasma RNA sequencing for genome-wide transcriptomic profiling and identification of pregnancy-associated transcripts.

Tsui NB, Jiang P, Wong YF, Leung TY, Chan KC, Chiu RW, Sun H, Lo YM.

Clin Chem. 2014 Jul;60(7):954-62. doi: 10.1373/clinchem.2014.221648. Epub 2014 Apr 16.


Investigation of biological factors influencing the placental mRNA profile in maternal plasma.

Tsui NB, Wong CS, Chow KC, Lo ES, Cheng YK.

Prenat Diagn. 2014 Mar;34(3):251-8. doi: 10.1002/pd.4300. Epub 2014 Jan 10.


Advanced technologies for studying circulating tumor cells at the protein level.

Chan CM, Au TC, Chan AT, Ma BB, Tsui NB, Ng SS, Hui EP, Chan LW, Ho WS, Yung BY, Wong SC.

Expert Rev Proteomics. 2013 Dec;10(6):579-89. doi: 10.1586/14789450.2013.858021. Review.


Noninvasive fetal RHD genotyping by microfluidics digital PCR using maternal plasma from two alloimmunized women with the variant RHD(IVS3+1G>A) allele.

Tsui NB, Hyland CA, Gardener GJ, Danon D, Fisk NM, Millard G, Flower RL, Lo YM.

Prenat Diagn. 2013 Dec;33(12):1214-6. doi: 10.1002/pd.4230. Epub 2013 Sep 19. No abstract available.


High resolution size analysis of fetal DNA in the urine of pregnant women by paired-end massively parallel sequencing.

Tsui NB, Jiang P, Chow KC, Su X, Leung TY, Sun H, Chan KC, Chiu RW, Lo YM.

PLoS One. 2012;7(10):e48319. doi: 10.1371/journal.pone.0048319. Epub 2012 Oct 31.


Recent advances in the analysis of fetal nucleic acids in maternal plasma.

Tsui NB, Lo YM.

Curr Opin Hematol. 2012 Nov;19(6):462-8. doi: 10.1097/MOH.0b013e328358e17a. Review.


Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA.

Tsui NB, Kadir RA, Chan KC, Chi C, Mellars G, Tuddenham EG, Leung TY, Lau TK, Chiu RW, Lo YM.

Blood. 2011 Mar 31;117(13):3684-91. doi: 10.1182/blood-2010-10-310789. Epub 2011 Jan 24. Erratum in: Blood. 2012 May 10;119(19):4577.


Synergy of total PLAC4 RNA concentration and measurement of the RNA single-nucleotide polymorphism allelic ratio for the noninvasive prenatal detection of trisomy 21.

Tsui NB, Akolekar R, Chiu RW, Chow KC, Leung TY, Lau TK, Nicolaides KH, Lo YM.

Clin Chem. 2010 Jan;56(1):73-81. doi: 10.1373/clinchem.2009.132662. Epub 2009 Nov 5.


Non-invasive prenatal detection of fetal trisomy 18 by RNA-SNP allelic ratio analysis using maternal plasma SERPINB2 mRNA: a feasibility study.

Tsui NB, Wong BC, Leung TY, Lau TK, Chiu RW, Lo YM.

Prenat Diagn. 2009 Nov;29(11):1031-7. doi: 10.1002/pd.2340.


Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood.

Heung MM, Jin S, Tsui NB, Ding C, Leung TY, Lau TK, Chiu RW, Lo YM.

PLoS One. 2009 Jun 10;4(6):e5858. doi: 10.1371/journal.pone.0005858.


Development of extraction protocols to improve the yield for fetal RNA in maternal plasma.

Heung MM, Tsui NB, Leung TY, Lau TK, Lo YM, Chiu RW.

Prenat Diagn. 2009 Mar;29(3):277-9. doi: 10.1002/pd.2191. No abstract available.


Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma.

Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY, Foo CH, Xie B, Tsui NB, Lun FM, Zee BC, Lau TK, Cantor CR, Lo YM.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20458-63. doi: 10.1073/pnas.0810641105. Epub 2008 Dec 10.


Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma.

Lun FM, Tsui NB, Chan KC, Leung TY, Lau TK, Charoenkwan P, Chow KC, Lo WY, Wanapirak C, Sanguansermsri T, Cantor CR, Chiu RW, Lo YM.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19920-5. doi: 10.1073/pnas.0810373105. Epub 2008 Dec 5.


Presence of donor-derived DNA and cells in the urine of sex-mismatched hematopoietic stem cell transplant recipients: implication for the transrenal hypothesis.

Hung EC, Shing TK, Chim SS, Yeung PC, Chan RW, Chik KW, Lee V, Tsui NB, Li CK, Wong CS, Chiu RW, Lo YM.

Clin Chem. 2009 Apr;55(4):715-22. doi: 10.1373/clinchem.2008.113530. Epub 2008 Oct 30.


Multiple thiopurine S-methyltransferase variation detection: a step toward personalized medicine.

Tsui NB.

Clin Chem. 2008 Oct;54(10):1598-9. doi: 10.1373/clinchem.2008.112896. No abstract available.


A microarray approach for systematic identification of placental-derived RNA markers in maternal plasma.

Tsui NB, Lo YM.

Methods Mol Biol. 2008;444:275-89. doi: 10.1007/978-1-59745-066-9_22.


Digital PCR for the molecular detection of fetal chromosomal aneuploidy.

Lo YM, Lun FM, Chan KC, Tsui NB, Chong KC, Lau TK, Leung TY, Zee BC, Cantor CR, Chiu RW.

Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13116-21. Epub 2007 Jul 30.


Genome-wide expression analysis using microarray identified complex signaling pathways modulated by hypoxia in nasopharyngeal carcinoma.

Sung FL, Hui EP, Tao Q, Li H, Tsui NB, Lo YM, Ma BB, To KF, Harris AL, Chan AT.

Cancer Lett. 2007 Aug 8;253(1):74-88. Epub 2007 Feb 22.


Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection.

Lo YM, Tsui NB, Chiu RW, Lau TK, Leung TN, Heung MM, Gerovassili A, Jin Y, Nicolaides KH, Cantor CR, Ding C.

Nat Med. 2007 Feb;13(2):218-23. Epub 2007 Jan 7.


Mass spectrometric detection of an SNP panel as an internal positive control for fetal DNA analysis in maternal plasma.

Chow KC, Chiu RW, Tsui NB, Ding C, Lau TK, Leung TN, Lo YM.

Clin Chem. 2007 Jan;53(1):141-2. No abstract available.


Placental RNA in maternal plasma: toward noninvasive fetal gene expression profiling.

Tsui NB, Lo YM.

Ann N Y Acad Sci. 2006 Sep;1075:96-102. Review.


Molecular analysis of circulating RNA in plasma.

Tsui NB, Ng EK, Lo YM.

Methods Mol Biol. 2006;336:123-34.


Detection of trisomy 21 by quantitative mass spectrometric analysis of single-nucleotide polymorphisms.

Tsui NB, Chiu RW, Ding C, El-Sheikhah A, Leung TN, Lau TK, Nicolaides KH, Lo YM.

Clin Chem. 2005 Dec;51(12):2358-62. No abstract available.


Circulating placental RNA in maternal plasma is associated with a preponderance of 5' mRNA fragments: implications for noninvasive prenatal diagnosis and monitoring.

Wong BC, Chiu RW, Tsui NB, Chan KC, Chan LW, Lau TK, Leung TN, Lo YM.

Clin Chem. 2005 Oct;51(10):1786-95. Epub 2005 Aug 4. Erratum in: Clin Chem. 2006 May;52(5):909.


Circulating corticotropin-releasing hormone mRNA in maternal plasma: relationship with gestational age and severity of preeclampsia.

Farina A, Chan CW, Chiu RW, Tsui NB, Carinci P, Concu M, Banzola I, Rizzo N, Lo YM.

Clin Chem. 2004 Oct;50(10):1851-4. No abstract available.


Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling.

Tsui NB, Chim SS, Chiu RW, Lau TK, Ng EK, Leung TN, Tong YK, Chan KC, Lo YM.

J Med Genet. 2004 Jun;41(6):461-7. No abstract available.


Effects of filtration on glyceraldehyde-3-phosphate dehydrogenase mRNA in the plasma of trauma patients and healthy individuals.

Rainer TH, Lam NY, Tsui NB, Ng EK, Chiu RW, Joynt GM, Lo YM.

Clin Chem. 2004 Jan;50(1):206-8. No abstract available.


The concentration of circulating corticotropin-releasing hormone mRNA in maternal plasma is increased in preeclampsia.

Ng EK, Leung TN, Tsui NB, Lau TK, Panesar NS, Chiu RW, Lo YM.

Clin Chem. 2003 May;49(5):727-31.


Quantitative analysis of circulating mitochondrial DNA in plasma.

Chiu RW, Chan LY, Lam NY, Tsui NB, Ng EK, Rainer TH, Lo YM.

Clin Chem. 2003 May;49(5):719-26. Erratum in: Clin Chem. 2004 Feb;50(2):461.


mRNA of placental origin is readily detectable in maternal plasma.

Ng EK, Tsui NB, Lau TK, Leung TN, Chiu RW, Panesar NS, Lit LC, Chan KW, Lo YM.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4748-53. Epub 2003 Mar 18.


Stability of endogenous and added RNA in blood specimens, serum, and plasma.

Tsui NB, Ng EK, Lo YM.

Clin Chem. 2002 Oct;48(10):1647-53.


Presence of filterable and nonfilterable mRNA in the plasma of cancer patients and healthy individuals.

Ng EK, Tsui NB, Lam NY, Chiu RW, Yu SC, Wong SC, Lo ES, Rainer TH, Johnson PJ, Lo YM.

Clin Chem. 2002 Aug;48(8):1212-7.

Supplemental Content

Support Center