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Items: 1 to 50 of 222

1.

HER2-overexpressing/amplified breast cancer as a testing ground for antibody-drug conjugate drug development in solid tumors.

Pegram MD, Miles D, Tsui CK, Zong Y.

Clin Cancer Res. 2019 Oct 3. pii: clincanres.1976.2019. doi: 10.1158/1078-0432.CCR-18-1976. [Epub ahead of print]

PMID:
31582515
2.

CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity.

Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC.

Nat Chem Biol. 2019 Oct;15(10):949-958. doi: 10.1038/s41589-019-0342-2. Epub 2019 Aug 26.

PMID:
31451760
3.

Design and Fabrication of a Push-Pull Electrostatic Actuated Cantilever Waveguide Scanner.

Wang WC, Gu K, Tsui C.

Micromachines (Basel). 2019 Jun 29;10(7). pii: E432. doi: 10.3390/mi10070432.

4.

Cost-effectiveness of preventing hepatitis B virus reactivation in patients with lymphoma and resolved HBV infection.

Tsou HH, Yang HC, Hsiao CF, Hsiung CA, Liu TW, Chuang MH, Wu HY, Hsu YT, Tsui CW, Chen PJ, Cheng AL, Hsu C; Taiwan Cooperative Oncology Group.

J Formos Med Assoc. 2019 Jun 21. pii: S0929-6646(19)30139-1. doi: 10.1016/j.jfma.2019.05.027. [Epub ahead of print]

5.

Draft Genome Sequences of Two Streptococcus pneumoniae Strains Causing Invasive Infections in Children in Qatar.

Tsui CKM, Sundararaju S, Al Mana H, Thomas E, Tang P, Hasan MR, Perez-Lopez A.

Microbiol Resour Announc. 2019 Jun 6;8(23). pii: e00511-19. doi: 10.1128/MRA.00511-19.

6.

Structures of the otopetrin proton channels Otop1 and Otop3.

Saotome K, Teng B, Tsui CCA, Lee WH, Tu YH, Kaplan JP, Sansom MSP, Liman ER, Ward AB.

Nat Struct Mol Biol. 2019 Jun;26(6):518-525. doi: 10.1038/s41594-019-0235-9. Epub 2019 Jun 3.

PMID:
31160780
7.

The Relationship between Macular Vessel Density and Thickness with Light Sensitivity in Myopic Eyes.

Tsui CK, Yang B, Yu S, Li J, Lu X, Xu Y, Lv L, Liang X.

Curr Eye Res. 2019 Oct;44(10):1104-1111. doi: 10.1080/02713683.2019.1627461. Epub 2019 Jun 13.

PMID:
31154859
8.

Bagasse Cellulose Grafted with an Amino-Terminated Hyperbranched Polymer for the Removal of Cr(VI) from Aqueous Solution.

Xia L, Huang Z, Zhong L, Xie F, Tang CY, Tsui CP.

Polymers (Basel). 2018 Aug 20;10(8). pii: E931. doi: 10.3390/polym10080931.

9.

In Vitro Priming and Hyper-Activation of Brain Microglia: an Assessment of Phenotypes.

Koss K, Churchward MA, Tsui C, Todd KG.

Mol Neurobiol. 2019 Sep;56(9):6409-6425. doi: 10.1007/s12035-019-1529-y. Epub 2019 Feb 25.

PMID:
30805836
10.

Evaluation of VITEK MS, Clin-ToF-II MS, Autof MS 1000 and VITEK 2 ANC card for identification of Bacteroides fragilis group isolates and antimicrobial susceptibilities of these isolates in a Chinese university hospital.

Wang Y, Chen XF, Xie XL, Xiao M, Yang Y, Zhang G, Zhang JJ, Duan SM, Zhang Q, Zhang P, Tsui C, Xu YC.

J Microbiol Immunol Infect. 2019 Jun;52(3):456-464. doi: 10.1016/j.jmii.2018.12.009. Epub 2019 Jan 4.

11.

Enzymatic Activity in Fractal Networks of Self-Assembling Peptides.

Koss KM, Tsui C, Unsworth LD.

Biomacromolecules. 2019 Jan 14;20(1):422-434. doi: 10.1021/acs.biomac.8b01496. Epub 2018 Dec 7.

PMID:
30457842
12.

Dynamic reorganisation of intermediate filaments coordinates early B-cell activation.

Tsui C, Maldonado P, Montaner B, Borroto A, Alarcon B, Bruckbauer A, Martinez-Martin N, Batista FD.

Life Sci Alliance. 2018 Aug 20;1(5):e201800060. doi: 10.26508/lsa.201800060. eCollection 2018 Oct.

13.

Biomaterials and glia: Progress on designs to modulate neuroinflammation.

Tsui C, Koss K, Churchward MA, Todd KG.

Acta Biomater. 2019 Jan 1;83:13-28. doi: 10.1016/j.actbio.2018.11.008. Epub 2018 Nov 7. Review.

PMID:
30414483
14.

Optic Nerve Stimulation System with Adaptive Wireless Powering and Data Telemetry.

Li X, Lu Y, Meng X, Tsui CY, Ki WH.

Micromachines (Basel). 2017 Dec 20;8(12). pii: E368. doi: 10.3390/mi8120368.

15.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

Haney MS, Bohlen CJ, Morgens DW, Ousey JA, Barkal AA, Tsui CK, Ego BK, Levin R, Kamber RA, Collins H, Tucker A, Li A, Vorselen D, Labitigan L, Crane E, Boyle E, Jiang L, Chan J, Rincón E, Greenleaf WJ, Li B, Snyder MP, Weissman IL, Theriot JA, Collins SR, Barres BA, Bassik MC.

Nat Genet. 2018 Dec;50(12):1716-1727. doi: 10.1038/s41588-018-0254-1. Epub 2018 Nov 5.

16.

Cryo-EM structure of the mechanically activated ion channel OSCA1.2.

Jojoa-Cruz S, Saotome K, Murthy SE, Tsui CCA, Sansom MS, Patapoutian A, Ward AB.

Elife. 2018 Nov 1;7. pii: e41845. doi: 10.7554/eLife.41845.

17.

Fibrillary Glomerulonephritis with Crescentic and Necrotizing Glomerulonephritis and Concurrent Thrombotic Microangiopathy.

Tsui C, Dokouhaki P, Prasad B.

Case Rep Nephrol Dial. 2018 Aug 31;8(2):182-191. doi: 10.1159/000492529. eCollection 2018 May-Aug.

18.

Effects of Compositional Tailoring on Drug Delivery Behaviours of Silica Xerogel/Polymer Core-shell Composite Nanoparticles.

Huang W, Tsui CP, Tang CY, Gu L.

Sci Rep. 2018 Aug 29;8(1):13002. doi: 10.1038/s41598-018-31070-9.

19.

Cryptic Speciation in Western North America and Eastern Eurasia of the Pathogens Responsible for Laminated Root Rot.

Leal I, Bergeron MJ, Feau N, Tsui CKM, Foord B, Pellow K, Hamelin RC, Sturrock RN.

Phytopathology. 2019 Mar;109(3):456-468. doi: 10.1094/PHYTO-12-17-0399-R. Epub 2019 Jan 7.

PMID:
30145938
20.

Abdominal muscle recruitment and its effect on the activity level of the hip and posterior thigh muscles during therapeutic exercises of the hip joint.

Tsang SMH, Lam AHM, Ng MHL, Ng KWK, Tsui COH, Yiu B.

J Electromyogr Kinesiol. 2018 Oct;42:10-19. doi: 10.1016/j.jelekin.2018.06.005. Epub 2018 Jun 12.

PMID:
29909357
21.

Protein Kinase C-β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis.

Tsui C, Martinez-Martin N, Gaya M, Maldonado P, Llorian M, Legrave NM, Rossi M, MacRae JI, Cameron AJ, Parker PJ, Leitges M, Bruckbauer A, Batista FD.

Immunity. 2018 Jun 19;48(6):1144-1159.e5. doi: 10.1016/j.immuni.2018.04.031. Epub 2018 Jun 5.

22.

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.

Sakthianandeswaren A, Parsons MJ, Mouradov D, MacKinnon RN, Catimel B, Liu S, Palmieri M, Love C, Jorissen RN, Li S, Whitehead L, Putoczki TL, Preaudet A, Tsui C, Nowell CJ, Ward RL, Hawkins NJ, Desai J, Gibbs P, Ernst M, Street I, Buchert M, Sieber OM.

Cancer Discov. 2018 Aug;8(8):988-1005. doi: 10.1158/2159-8290.CD-17-0909. Epub 2018 Jun 7.

23.

Ultra-Low-Power Smart Electronic Nose System Based on Three-Dimensional Tin Oxide Nanotube Arrays.

Chen J, Chen Z, Boussaid F, Zhang D, Pan X, Zhao H, Bermak A, Tsui CY, Wang X, Fan Z.

ACS Nano. 2018 Jun 26;12(6):6079-6088. doi: 10.1021/acsnano.8b02371. Epub 2018 Jun 4.

PMID:
29792677
24.

Beaver Fever: Whole-Genome Characterization of Waterborne Outbreak and Sporadic Isolates To Study the Zoonotic Transmission of Giardiasis.

Tsui CK, Miller R, Uyaguari-Diaz M, Tang P, Chauve C, Hsiao W, Isaac-Renton J, Prystajecky N.

mSphere. 2018 Apr 25;3(2). pii: e00090-18. doi: 10.1128/mSphere.00090-18. Print 2018 Apr 25.

25.

Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms.

Peng J, Santiago IJ, Ahn C, Gur B, Tsui CK, Su Z, Xu C, Karakhanyan A, Silies M, Pecot MY.

Elife. 2018 Mar 7;7. pii: e33962. doi: 10.7554/eLife.33962.

26.

CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity.

Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD.

Nat Genet. 2018 Apr;50(4):603-612. doi: 10.1038/s41588-018-0070-7. Epub 2018 Mar 5.

27.

dCas9-targeted locus-specific protein isolation method identifies histone gene regulators.

Tsui C, Inouye C, Levy M, Lu A, Florens L, Washburn MP, Tjian R.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2734-E2741. doi: 10.1073/pnas.1718844115. Epub 2018 Mar 5.

28.

Genome-Enhanced Detection and Identification (GEDI) of plant pathogens.

Feau N, Beauseigle S, Bergeron MJ, Bilodeau GJ, Birol I, Cervantes-Arango S, Dhillon B, Dale AL, Herath P, Jones SJM, Lamarche J, Ojeda DI, Sakalidis ML, Taylor G, Tsui CKM, Uzunovic A, Yueh H, Tanguay P, Hamelin RC.

PeerJ. 2018 Feb 22;6:e4392. doi: 10.7717/peerj.4392. eCollection 2018.

29.

Transcriptional profile of the human skin pathogenic fungus Mucor irregularis in response to low oxygen.

Xu W, Peng J, Li D, Tsui CKM, Long Z, Wang Q, Mei H, Liu W.

Med Mycol. 2018 Jul 1;56(5):631-644. doi: 10.1093/mmy/myx081.

PMID:
29420826
30.

Melatonin attenuated retinal neovascularization and neuroglial dysfunction by inhibition of HIF-1α-VEGF pathway in oxygen-induced retinopathy mice.

Xu Y, Lu X, Hu Y, Yang B, Tsui CK, Yu S, Lu L, Liang X.

J Pineal Res. 2018 May;64(4):e12473. doi: 10.1111/jpi.12473. Epub 2018 Mar 8.

PMID:
29411894
31.

Accounting for Debye sheath expansion for proud Langmuir probes in magnetic confinement fusion plasmas.

Tsui CK, Boedo JA, Stangeby PC; TCV Team.

Rev Sci Instrum. 2018 Jan;89(1):013505. doi: 10.1063/1.4995353.

PMID:
29390679
32.

Association of long-term glycaemic control on tear break-up times and dry eye symptoms in Chinese patients with type 2 diabetes.

Ma A, Mak MS, Shih KC, Tsui CK, Cheung RK, Lee SH, Leung H, Leung JN, Leung JT, Van-Boswell MZ, Wong MT, Ng AL, Lee CH, Jhanji V, Tong L.

Clin Exp Ophthalmol. 2018 Aug;46(6):608-615. doi: 10.1111/ceo.13146. Epub 2018 Feb 23.

PMID:
29345402
33.

Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages.

Wong D, Li W, Chao JD, Zhou P, Narula G, Tsui C, Ko M, Xie J, Martinez-Frailes C, Av-Gay Y.

Sci Rep. 2018 Jan 9;8(1):155. doi: 10.1038/s41598-017-18547-9.

34.

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.

Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, Aid M, Tsui C, Maldonado P, Nair U, Ghneim K, Fallon PG, Sekaly RP, Barouch DH, Shalek AK, Bruckbauer A, Strid J, Batista FD.

Cell. 2018 Jan 25;172(3):517-533.e20. doi: 10.1016/j.cell.2017.11.036. Epub 2017 Dec 14.

35.

Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy.

Saison-Ridinger M, DelGiorno KE, Zhang T, Kraus A, French R, Jaquish D, Tsui C, Erikson G, Spike BT, Shokhirev MN, Liddle C, Yu RT, Downes M, Evans RM, Saghatelian A, Lowy AM, Wahl GM.

PLoS One. 2017 Dec 6;12(12):e0189051. doi: 10.1371/journal.pone.0189051. eCollection 2017.

36.

Transcriptional profile of the human skin pathogenic fungus Mucor irregularis in response to low oxygen.

Xu W, Peng J, Li D, Tsui CKM, Long Z, Wang Q, Mei H, Liu W.

Med Mycol. 2018 Oct 1;56(7):e2. doi: 10.1093/mmy/myx132. No abstract available.

PMID:
29182775
37.

Integrated Supported Employment for People With Schizophrenia in Mainland China: A Randomized Controlled Trial.

Zhang GF, Tsui CM, Lu AJB, Yu LB, Tsang HWH, Li D.

Am J Occup Ther. 2017 Nov/Dec;71(6):7106165020p1-7106165020p8. doi: 10.5014/ajot.2017.024802.

PMID:
29135426
38.

Salubrinal attenuated retinal neovascularization by inhibiting CHOP-HIF1α-VEGF pathways.

Hu Y, Lu X, Xu Y, Lu L, Yu S, Cheng Q, Yang B, Tsui CK, Ye D, Huang J, Liang X.

Oncotarget. 2017 Aug 24;8(44):77219-77232. doi: 10.18632/oncotarget.20431. eCollection 2017 Sep 29.

39.

Genome Sequences of the Mycobacterium tuberculosis H37Rv-ptkA Deletion Mutant and Its Parental Strain.

Tsui CKM, Wong D, Narula G, Gardy JL, Hsiao WWH, Av-Gay Y.

Genome Announc. 2017 Nov 2;5(44). pii: e01156-17. doi: 10.1128/genomeA.01156-17.

40.

Comparison of the Impact of Wikipedia, UpToDate, and a Digital Textbook on Short-Term Knowledge Acquisition Among Medical Students: Randomized Controlled Trial of Three Web-Based Resources.

Scaffidi MA, Khan R, Wang C, Keren D, Tsui C, Garg A, Brar S, Valoo K, Bonert M, de Wolff JF, Heilman J, Grover SC.

JMIR Med Educ. 2017 Oct 31;3(2):e20. doi: 10.2196/mededu.8188.

41.

Anticoagulation for Thromboembolic Risk Reduction in Adults With Congenital Heart Disease.

Wan D, Tsui C, Kiess M, Grewal J, Krahn AD, Chakrabarti S.

Can J Cardiol. 2017 Dec;33(12):1597-1603. doi: 10.1016/j.cjca.2017.08.009. Epub 2017 Aug 19. Review.

PMID:
29066332
42.

FK506 suppresses hypoxia‑induced inflammation and protects tight junction function via the CaN‑NFATc1 signaling pathway in retinal microvascular epithelial cells.

Hu Y, Yang B, Xu Y, Jiang L, Tsui CK, Liang X.

Mol Med Rep. 2017 Nov;16(5):6974-6980. doi: 10.3892/mmr.2017.7475. Epub 2017 Sep 12.

PMID:
28901449
43.

Modulation of Staphylococcus aureus Response to Antimicrobials by the Candida albicans Quorum Sensing Molecule Farnesol.

Kong EF, Tsui C, Kucharíková S, Van Dijck P, Jabra-Rizk MA.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01573-17. doi: 10.1128/AAC.01573-17. Print 2017 Dec.

44.

The influence of the mating type on virulence of Mucor irregularis.

Xu W, Liang G, Peng J, Long Z, Li D, Fu M, Wang Q, Shen Y, Lv G, Mei H, Tsui CKM, Liu W.

Sci Rep. 2017 Sep 6;7(1):10629. doi: 10.1038/s41598-017-10954-2.

45.

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens.

Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC.

Nat Commun. 2017 May 5;8:15178. doi: 10.1038/ncomms15178.

46.

Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression.

Poh AR, Love CG, Masson F, Preaudet A, Tsui C, Whitehead L, Monard S, Khakham Y, Burstroem L, Lessene G, Sieber O, Lowell C, Putoczki TL, O'Donoghue RJJ, Ernst M.

Cancer Cell. 2017 Apr 10;31(4):563-575.e5. doi: 10.1016/j.ccell.2017.03.006.

47.

Hyper-elastic modeling and mechanical behavior investigation of porous poly-D-L-lactide/nano-hydroxyapatite scaffold material.

Han QF, Wang ZW, Tang CY, Chen L, Tsui CP, Law WC.

J Mech Behav Biomed Mater. 2017 Jul;71:262-270. doi: 10.1016/j.jmbbm.2017.03.032. Epub 2017 Mar 28.

PMID:
28365543
48.

Genetic and genomic evidence of niche partitioning and adaptive radiation in mountain pine beetle fungal symbionts.

Ojeda Alayon DI, Tsui CK, Feau N, Capron A, Dhillon B, Zhang Y, Massoumi Alamouti S, Boone CK, Carroll AL, Cooke JE, Roe AD, Sperling FA, Hamelin RC.

Mol Ecol. 2017 Apr;26(7):2077-2091. doi: 10.1111/mec.14074. Epub 2017 Mar 22.

PMID:
28231417
49.

A switch from canonical to noncanonical autophagy shapes B cell responses.

Martinez-Martin N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, Tsui C, Burbage M, Keppler SJ, Montaner B, Jefferies HB, Nair U, Zhao YG, Domart MC, Collinson L, Bruckbauer A, Tooze SA, Batista FD.

Science. 2017 Feb 10;355(6325):641-647. doi: 10.1126/science.aal3908.

50.

Finding host targets for HIV therapy.

Tsui CK, Gupta A, Bassik MC.

Nat Genet. 2017 Jan 31;49(2):175-176. doi: 10.1038/ng.3777.

PMID:
28138150

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