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Items: 1 to 50 of 115

1.

Liraglutide Improves Renal Endothelial Function in Obese Zucker Rats on a High-Salt Diet.

Sukumaran V, Tsuchimochi H, Sonobe T, Shirai M, Pearson JT.

J Pharmacol Exp Ther. 2019 Jun;369(3):375-388. doi: 10.1124/jpet.118.254821. Epub 2019 Mar 25.

PMID:
30910920
2.

Transcriptional cofactor Vgll2 is required for functional adaptations of skeletal muscle induced by chronic overload.

Honda M, Tsuchimochi H, Hitachi K, Ohno S.

J Cell Physiol. 2019 Feb 6. doi: 10.1002/jcp.28239. [Epub ahead of print]

PMID:
30724341
3.

Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice.

Takeshita H, Yamamoto K, Nozato S, Takeda M, Fukada SI, Inagaki T, Tsuchimochi H, Shirai M, Nozato Y, Fujimoto T, Imaizumi Y, Yokoyama S, Nagasawa M, Hamano G, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Takeda S, Takahashi T, Akasaka H, Itoh N, Takami Y, Takeya Y, Sugimoto K, Nakagami H, Rakugi H.

J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):975-986. doi: 10.1002/jcsm.12334. Epub 2018 Sep 11.

4.

Ghrelin Pre-treatment Attenuates Local Oxidative Stress and End Organ Damage During Cardiopulmonary Bypass in Anesthetized Rats.

Sukumaran V, Tsuchimochi H, Fujii Y, Hosoda H, Kangawa K, Akiyama T, Shirai M, Tatsumi E, Pearson JT.

Front Physiol. 2018 Mar 9;9:196. doi: 10.3389/fphys.2018.00196. eCollection 2018.

5.

Drinking by amphibious fish: convergent evolution of thirst mechanisms during vertebrate terrestrialization.

Katayama Y, Sakamoto T, Saito K, Tsuchimochi H, Kaiya H, Watanabe T, Pearson JT, Takei Y.

Sci Rep. 2018 Jan 12;8(1):625. doi: 10.1038/s41598-017-18611-4.

6.

Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model.

Pearson JT, Yoshimoto M, Chen YC, Sultani R, Edgley AJ, Nakaoka H, Nishida M, Umetani K, Waddingham MT, Jin HL, Zhang Y, Kelly DJ, Schwenke DO, Inagaki T, Tsuchimochi H, Komuro I, Yamashita S, Shirai M.

Sci Rep. 2017 Dec 22;7(1):18108. doi: 10.1038/s41598-017-18485-6.

7.

Analysis of the microvascular morphology and hemodynamics of breast cancer in mice using SPring-8 synchrotron radiation microangiography.

Torii M, Fukui T, Inoue M, Kanao S, Umetani K, Shirai M, Inagaki T, Tsuchimochi H, Pearson JT, Toi M.

J Synchrotron Radiat. 2017 Sep 1;24(Pt 5):1039-1047. doi: 10.1107/S1600577517008372. Epub 2017 Aug 2.

8.

Influence of coronary architecture on the variability in myocardial infarction induced by coronary ligation in rats.

Kainuma S, Miyagawa S, Fukushima S, Tsuchimochi H, Sonobe T, Fujii Y, Pearson JT, Saito A, Harada A, Toda K, Shirai M, Sawa Y.

PLoS One. 2017 Aug 24;12(8):e0183323. doi: 10.1371/journal.pone.0183323. eCollection 2017.

9.

Azilsartan ameliorates diabetic cardiomyopathy in young db/db mice through the modulation of ACE-2/ANG 1-7/Mas receptor cascade.

Sukumaran V, Tsuchimochi H, Tatsumi E, Shirai M, Pearson JT.

Biochem Pharmacol. 2017 Nov 15;144:90-99. doi: 10.1016/j.bcp.2017.07.022. Epub 2017 Aug 5.

PMID:
28789938
10.

Modified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice.

Takeshita H, Yamamoto K, Nozato S, Inagaki T, Tsuchimochi H, Shirai M, Yamamoto R, Imaizumi Y, Hongyo K, Yokoyama S, Takeda M, Oguro R, Takami Y, Itoh N, Takeya Y, Sugimoto K, Fukada SI, Rakugi H.

Sci Rep. 2017 Feb 8;7:42323. doi: 10.1038/srep42323.

11.

Chronic intermittent hypoxia accelerates coronary microcirculatory dysfunction in insulin-resistant Goto-Kakizaki rats.

Chen YC, Inagaki T, Fujii Y, Schwenke DO, Tsuchimochi H, Edgley AJ, Umetani K, Zhang Y, Kelly DJ, Yoshimoto M, Nagai H, Evans RG, Kuwahira I, Shirai M, Pearson JT.

Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1.

12.

Sympathetic hyper-excitation in obesity and pulmonary hypertension: physiological relevance to the 'obesity paradox'.

Diong C, Jones PP, Tsuchimochi H, Gray EA, Hughes G, Inagaki T, Bussey CT, Fujii Y, Umetani K, Shirai M, Schwenke DO.

Int J Obes (Lond). 2016 Jun;40(6):938-46. doi: 10.1038/ijo.2016.33. Epub 2016 Feb 23.

PMID:
27001546
13.

Ghrelin Promotes Functional Angiogenesis in a Mouse Model of Critical Limb Ischemia Through Activation of Proangiogenic MicroRNAs.

Katare R, Rawal S, Munasinghe PE, Tsuchimochi H, Inagaki T, Fujii Y, Dixit P, Umetani K, Kangawa K, Shirai M, Schwenke DO.

Endocrinology. 2016 Feb;157(2):432-45. doi: 10.1210/en.2015-1799. Epub 2015 Dec 16.

PMID:
26672806
14.

Microvascular oxygen partial pressure during hyperbaric oxygen in diabetic rat skeletal muscle.

Yamakoshi K, Yagishita K, Tsuchimochi H, Inagaki T, Shirai M, Poole DC, Kano Y.

Am J Physiol Regul Integr Comp Physiol. 2015 Dec 15;309(12):R1512-20. doi: 10.1152/ajpregu.00380.2015. Epub 2015 Oct 14.

15.

Chronic Rho-kinase inhibition improves left ventricular contractile dysfunction in early type-1 diabetes by increasing myosin cross-bridge extension.

Waddingham MT, Edgley AJ, Astolfo A, Inagaki T, Fujii Y, Du CK, Zhan DY, Tsuchimochi H, Yagi N, Kelly DJ, Shirai M, Pearson JT.

Cardiovasc Diabetol. 2015 Jul 22;14:92. doi: 10.1186/s12933-015-0256-6.

16.

Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathy.

Waddingham MT, Edgley AJ, Tsuchimochi H, Kelly DJ, Shirai M, Pearson JT.

World J Diabetes. 2015 Jul 10;6(7):943-60. doi: 10.4239/wjd.v6.i7.943. Review.

17.

Pulmonary Macrophages Attenuate Hypoxic Pulmonary Vasoconstriction via β3AR/iNOS Pathway in Rats Exposed to Chronic Intermittent Hypoxia.

Nagai H, Kuwahira I, Schwenke DO, Tsuchimochi H, Nara A, Ogura S, Sonobe T, Inagaki T, Fujii Y, Yamaguchi R, Wingenfeld L, Umetani K, Shimosawa T, Yoshida K, Uemura K, Pearson JT, Shirai M.

PLoS One. 2015 Jul 1;10(7):e0131923. doi: 10.1371/journal.pone.0131923. eCollection 2015.

18.

Ghrelin Supresses Sympathetic Hyperexcitation in Acute Heart Failure in Male Rats: Assessing Centrally and Peripherally Mediated Pathways.

Shirai M, Joe N, Tsuchimochi H, Sonobe T, Schwenke DO.

Endocrinology. 2015 Sep;156(9):3309-16. doi: 10.1210/EN.2015-1333. Epub 2015 Jun 29.

PMID:
26121343
19.

Treadmill running improves hindlimb arteriolar endothelial function in type 1 diabetic mice as visualized by X-ray microangiography.

Sonobe T, Tsuchimochi H, Schwenke DO, Pearson JT, Shirai M.

Cardiovasc Diabetol. 2015 May 13;14:51. doi: 10.1186/s12933-015-0217-0.

20.

APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.

Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N.

Dev Cell. 2015 May 4;33(3):247-59. doi: 10.1016/j.devcel.2015.02.024. Epub 2015 Apr 23.

21.

Functional and Electrical Integration of Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Myocardial Infarction Rat Heart.

Higuchi T, Miyagawa S, Pearson JT, Fukushima S, Saito A, Tsuchimochi H, Sonobe T, Fujii Y, Yagi N, Astolfo A, Shirai M, Sawa Y.

Cell Transplant. 2015;24(12):2479-89. doi: 10.3727/096368914X685799. Epub 2015 Jan 20.

PMID:
25606821
22.

Cell-sheet therapy with omentopexy promotes arteriogenesis and improves coronary circulation physiology in failing heart.

Kainuma S, Miyagawa S, Fukushima S, Pearson J, Chen YC, Saito A, Harada A, Shiozaki M, Iseoka H, Watabe T, Watabe H, Horitsugi G, Ishibashi M, Ikeda H, Tsuchimochi H, Sonobe T, Fujii Y, Naito H, Umetani K, Shimizu T, Okano T, Kobayashi E, Daimon T, Ueno T, Kuratani T, Toda K, Takakura N, Hatazawa J, Shirai M, Sawa Y.

Mol Ther. 2015 Feb;23(2):374-86. doi: 10.1038/mt.2014.225. Epub 2014 Nov 25.

23.

β2-Adrenergic receptor-dependent attenuation of hypoxic pulmonary vasoconstriction prevents progression of pulmonary arterial hypertension in intermittent hypoxic rats.

Nagai H, Kuwahira I, Schwenke DO, Tsuchimochi H, Nara A, Inagaki T, Ogura S, Fujii Y, Umetani K, Shimosawa T, Yoshida K, Pearson JT, Uemura K, Shirai M.

PLoS One. 2014 Oct 28;9(10):e110693. doi: 10.1371/journal.pone.0110693. eCollection 2014.

24.

Pulmonary vascular tone is dependent on the central modulation of sympathetic nerve activity following chronic intermittent hypoxia.

Shirai M, Tsuchimochi H, Nagai H, Gray E, Pearson JT, Sonobe T, Yoshimoto M, Inagaki T, Fujii Y, Umetani K, Kuwahira I, Schwenke DO.

Basic Res Cardiol. 2014;109(5):432. doi: 10.1007/s00395-014-0432-y. Epub 2014 Aug 20.

PMID:
25139633
25.

Carotid Endarterectomy for Pseudo-occlusion of the Cervical Internal Carotid Artery.

Hirata Y, Sakata N, Tsuchimochi H, Tsugu H, Onishi H, Inoue T.

Acta Neurochir Suppl. 2014;119:91-6. doi: 10.1007/978-3-319-02411-0_16.

PMID:
24728640
26.

Increased dietary salt intake enhances the exercise pressor reflex.

Yamauchi K, Tsuchimochi H, Stone AJ, Stocker SD, Kaufman MP.

Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H450-4. doi: 10.1152/ajpheart.00813.2013. Epub 2013 Nov 22.

27.

Acute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculation.

Pearson JT, Jenkins MJ, Edgley AJ, Sonobe T, Joshi M, Waddingham MT, Fujii Y, Schwenke DO, Tsuchimochi H, Yoshimoto M, Umetani K, Kelly DJ, Shirai M.

Cardiovasc Diabetol. 2013 Aug 1;12:111. doi: 10.1186/1475-2840-12-111.

28.

Assessment of the serotonin pathway as a therapeutic target for pulmonary hypertension.

Gray EA, Tsuchimochi H, Pearson JT, Sonobe T, Fujii Y, Yoshimoto M, Umetani K, Shirai M, Schwenke DO.

J Synchrotron Radiat. 2013 Sep;20(Pt 5):756-64. doi: 10.1107/S0909049513021213. Epub 2013 Aug 8.

PMID:
23955040
29.

Hyperoxic condition promotes an inflammatory response during cardiopulmonary bypass in a rat model.

Fujii Y, Shirai M, Tsuchimochi H, Pearson JT, Takewa Y, Tatsumi E, Taenaka Y.

Artif Organs. 2013 Dec;37(12):1034-40. doi: 10.1111/aor.12125. Epub 2013 Jul 19.

PMID:
23865518
30.

Dynamic exercise improves cognitive function in association with increased prefrontal oxygenation.

Endo K, Matsukawa K, Liang N, Nakatsuka C, Tsuchimochi H, Okamura H, Hamaoka T.

J Physiol Sci. 2013 Jul;63(4):287-98. doi: 10.1007/s12576-013-0267-6. Epub 2013 May 10.

PMID:
23661275
31.

Impaired pulmonary blood flow distribution in congestive heart failure assessed using synchrotron radiation microangiography.

Shirai M, Beard M, Pearson JT, Sonobe T, Tsuchimochi H, Fujii Y, Gray E, Umetani K, Schwenke DO.

J Synchrotron Radiat. 2013 May;20(Pt 3):441-8. doi: 10.1107/S0909049513007413. Epub 2013 Apr 6.

PMID:
23592623
32.

In vivo monitoring of acetylcholine release from cardiac vagal nerve endings in anesthetized mice.

Zhan DY, Du CK, Akiyama T, Sonobe T, Tsuchimochi H, Shimizu S, Kawada T, Shirai M.

Auton Neurosci. 2013 Jun;176(1-2):91-4. doi: 10.1016/j.autneu.2013.02.014. Epub 2013 Mar 15.

PMID:
23499513
33.

Synchrotron radiation imaging for advancing our understanding of cardiovascular function.

Shirai M, Schwenke DO, Tsuchimochi H, Umetani K, Yagi N, Pearson JT.

Circ Res. 2013 Jan 4;112(1):209-21. doi: 10.1161/CIRCRESAHA.111.300096. Review.

PMID:
23287456
34.

Insufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model.

Fujii Y, Shirai M, Inamori S, Shimouchi A, Sonobe T, Tsuchimochi H, Pearson JT, Takewa Y, Tatsumi E, Taenaka Y.

Artif Organs. 2013 Feb;37(2):136-41. doi: 10.1111/j.1525-1594.2012.01535.x. Epub 2012 Sep 30.

PMID:
23020073
35.

Modulation of radial blood flow during Braille character discrimination task.

Murata J, Matsukawa K, Komine H, Tsuchimochi H.

Acta Physiol Hung. 2012 Mar;99(1):25-32. doi: 10.1556/APhysiol.99.2012.1.3.

PMID:
22425805
36.

Blockade of acid sensing ion channels attenuates the augmented exercise pressor reflex in rats with chronic femoral artery occlusion.

Tsuchimochi H, Yamauchi K, McCord JL, Kaufman MP.

J Physiol. 2011 Dec 15;589(Pt 24):6173-89. doi: 10.1113/jphysiol.2011.217851. Epub 2011 Oct 17.

37.

Blockade of the TP receptor attenuates the exercise pressor reflex in decerebrated rats with chronic femoral artery occlusion.

Leal AK, McCord JL, Tsuchimochi H, Kaufman MP.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H2140-6. doi: 10.1152/ajpheart.00403.2011. Epub 2011 Aug 19.

38.

Surgical strategy for intracranial endodermal cyst--case report.

Hashimoto M, Yamamoto J, Takahashi M, Saito T, Kitagawa T, Tsuchimochi H, Fukushima Y, Harada T, Nakashima Y, Nishizawa S.

Neurol Med Chir (Tokyo). 2011;51(7):531-4.

39.

Tempol attenuates the exercise pressor reflex independently of neutralizing reactive oxygen species in femoral artery ligated rats.

McCord JL, Tsuchimochi H, Yamauchi K, Leal A, Kaufman MP.

J Appl Physiol (1985). 2011 Oct;111(4):971-9. doi: 10.1152/japplphysiol.00535.2011. Epub 2011 Jul 7.

40.

Dorsal root tetrodotoxin-resistant sodium channels do not contribute to the augmented exercise pressor reflex in rats with chronic femoral artery occlusion.

Tsuchimochi H, McCord JL, Leal AK, Kaufman MP.

Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H652-63. doi: 10.1152/ajpheart.00859.2010. Epub 2010 Nov 12.

41.

P2X2/3 and P2X3 receptors contribute to the metaboreceptor component of the exercise pressor reflex.

McCord JL, Tsuchimochi H, Kaufman MP.

J Appl Physiol (1985). 2010 Nov;109(5):1416-23. doi: 10.1152/japplphysiol.00774.2010. Epub 2010 Aug 26.

42.

Peripheral mu-opioid receptors attenuate the augmented exercise pressor reflex in rats with chronic femoral artery occlusion.

Tsuchimochi H, McCord JL, Kaufman MP.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H557-65. doi: 10.1152/ajpheart.00387.2010. Epub 2010 Jun 11.

43.

Chronic femoral artery occlusion augments exercise pressor reflex in decerebrated rats.

Tsuchimochi H, McCord JL, Hayes SG, Koba S, Kaufman MP.

Am J Physiol Heart Circ Physiol. 2010 Jul;299(1):H106-13. doi: 10.1152/ajpheart.00141.2010. Epub 2010 Apr 23.

44.

[A case of herpetic meningoencephalitis associated with massive intracerebral hemorrhage during acyclovir treatment: a rare complication].

Fukushima Y, Tsuchimochi H, Hashimoto M, Yubi T, Nakajima Y, Fukushima T, Inoue T.

No Shinkei Geka. 2010 Feb;38(2):171-6. Japanese.

PMID:
20166530
45.

Centrally evoked increase in adrenal sympathetic outflow elicits immediate secretion of adrenaline in anaesthetized rats.

Tsuchimochi H, Nakamoto T, Matsukawa K.

Exp Physiol. 2010 Jan;95(1):93-106. doi: 10.1113/expphysiol.2009.048553. Epub 2009 Aug 21.

46.

Acid-sensing ion channels contribute to the metaboreceptor component of the exercise pressor reflex.

McCord JL, Tsuchimochi H, Kaufman MP.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H443-9. doi: 10.1152/ajpheart.00328.2009. Epub 2009 May 22.

47.

Changes in pulmonary blood flow distribution in monocrotaline compared with hypoxia-induced models of pulmonary hypertension: assessed using synchrotron radiation.

Schwenke DO, Pearson JT, Shimochi A, Kangawa K, Tsuchimochi H, Umetani K, Shirai M, Cragg PA.

J Hypertens. 2009 Jul;27(7):1410-9. doi: 10.1097/HJH.0b013e32832af6a1.

PMID:
19424090
48.

Both central command and exercise pressor reflex activate cardiac sympathetic nerve activity in decerebrate cats.

Tsuchimochi H, Hayes SG, McCord JL, Kaufman MP.

Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1157-63. doi: 10.1152/ajpheart.01219.2008. Epub 2009 Feb 20.

49.

Synchrotron-based angiography for investigation of the regulation of vasomotor function in the microcirculation in vivo.

Shirai M, Schwenke DO, Eppel GA, Evans RG, Edgley AJ, Tsuchimochi H, Umetani K, Pearson JT.

Clin Exp Pharmacol Physiol. 2009 Jan;36(1):107-16. doi: 10.1111/j.1440-1681.2008.05073.x. Epub 2008 Oct 15. Review.

PMID:
18986322
50.

Sympathetic cholinergic nerve contributes to increased muscle blood flow at the onset of voluntary static exercise in conscious cats.

Komine H, Matsukawa K, Tsuchimochi H, Nakamoto T, Murata J.

Am J Physiol Regul Integr Comp Physiol. 2008 Oct;295(4):R1251-62. doi: 10.1152/ajpregu.00076.2008. Epub 2008 Aug 13.

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