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Items: 18

1.

Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.

Gui X, Deng M, Song H, Chen Y, Xie J, Li Z, He L, Huang F, Xu Y, Anami Y, Yu H, Yu C, Li L, Yuan Z, Xu X, Wang Q, Chai Y, Huang T, Shi Y, Tsuchikama K, Liao XC, Xia N, Gao GF, Zhang N, Zhang CC, An Z.

Cancer Immunol Res. 2019 Aug;7(8):1244-1257. doi: 10.1158/2326-6066.CIR-19-0036. Epub 2019 Jun 18.

PMID:
31213474
2.

[Novel Chemical Linkers for Next-generation Antibody-drug Conjugates(ADCs)].

Tsuchikama K.

Yakugaku Zasshi. 2019;139(2):209-219. doi: 10.1248/yakushi.18-00169-3. Review. Japanese.

3.

Glutamic acid-valine-citrulline linkers ensure stability and efficacy of antibody-drug conjugates in mice.

Anami Y, Yamazaki CM, Xiong W, Gui X, Zhang N, An Z, Tsuchikama K.

Nat Commun. 2018 Jun 28;9(1):2512. doi: 10.1038/s41467-018-04982-3.

4.

Enzymatic conjugation using branched linkers for constructing homogeneous antibody-drug conjugates with high potency.

Anami Y, Xiong W, Gui X, Deng M, Zhang CC, Zhang N, An Z, Tsuchikama K.

Org Biomol Chem. 2017 Jul 5;15(26):5635-5642. doi: 10.1039/c7ob01027c.

PMID:
28649690
5.

Truncated Autoinducing Peptide Conjugates Selectively Recognize and Kill Staphylococcus aureus.

Tsuchikama K, Shimamoto Y, Anami Y.

ACS Infect Dis. 2017 Jun 9;3(6):406-410. doi: 10.1021/acsinfecdis.7b00013. Epub 2017 Feb 6.

PMID:
28155275
6.

Antibody-drug conjugates: recent advances in conjugation and linker chemistries.

Tsuchikama K, An Z.

Protein Cell. 2018 Jan;9(1):33-46. doi: 10.1007/s13238-016-0323-0. Epub 2016 Oct 14. Review.

7.

Dissecting AI-2-mediated quorum sensing through C5-analogue synthesis and biochemical analysis.

Collins KC, Tsuchikama K, Lowery CA, Zhu J, Janda KD.

Tetrahedron. 2015 Jun;72(25):3593-3598.

8.

Glycation Reactivity of a Quorum-Sensing Signaling Molecule.

Tsuchikama K, Gooyit M, Harris TL, Zhu J, Globisch D, Kaufmann GF, Janda KD.

Angew Chem Int Ed Engl. 2016 Mar 14;55(12):4002-6. doi: 10.1002/anie.201511911. Epub 2016 Feb 17.

9.

Modulating cocaine vaccine potency through hapten fluorination.

Cai X, Tsuchikama K, Janda KD.

J Am Chem Soc. 2013 Feb 27;135(8):2971-4. doi: 10.1021/ja400356g. Epub 2013 Feb 14.

10.

C4-alkoxy-HPD: a potent class of synthetic modulators surpassing nature in AI-2 quorum sensing.

Tsuchikama K, Zhu J, Lowery CA, Kaufmann GF, Janda KD.

J Am Chem Soc. 2012 Aug 22;134(33):13562-4. doi: 10.1021/ja305532y. Epub 2012 Aug 9.

11.

Highly enantioselective synthesis of silahelicenes using Ir-catalyzed [2+2+2] cycloaddition.

Shibata T, Uchiyama T, Yoshinami Y, Takayasu S, Tsuchikama K, Endo K.

Chem Commun (Camb). 2012 Jan 30;48(9):1311-3. doi: 10.1039/c1cc16762f. Epub 2011 Dec 13.

PMID:
22158937
12.

Probing autoinducer-2 based quorum sensing: the biological consequences of molecules unable to traverse equilibrium states.

Tsuchikama K, Lowery CA, Janda KD.

J Org Chem. 2011 Sep 2;76(17):6981-9. doi: 10.1021/jo200882k. Epub 2011 Jun 28.

13.

A cross-over inhibitor of the botulinum neurotoxin light chain B: a natural product implicating an exosite mechanism of action.

Salzameda NT, Eubanks LM, Zakhari JS, Tsuchikama K, DeNunzio NJ, Allen KN, Hixon MS, Janda KD.

Chem Commun (Camb). 2011 Feb 14;47(6):1713-5. doi: 10.1039/c0cc04078a. Epub 2011 Jan 4.

14.

Cationic Ir(I)-Catalyzed sp(3) C-H Bond Alkenylation of Amides with Alkynes.

Tsuchikama K, Kasagawa M, Endo K, Shibata T.

Org Lett. 2009 Apr 16;11(8):1821-3. doi: 10.1021/ol900404r.

PMID:
19354323
15.

Recent advances in enantioselective [2 + 2 + 2] cycloaddition.

Shibata T, Tsuchikama K.

Org Biomol Chem. 2008 Apr 21;6(8):1317-23. doi: 10.1039/b720031e. Epub 2008 Mar 12. Review.

PMID:
18385836
16.

Rh-catalyzed cyclization of diynes and enynes initiated by carbonyl-directed activation of aromatic and vinylic C-H bonds.

Tsuchikama K, Kuwata Y, Tahara YK, Yoshinami Y, Shibata T.

Org Lett. 2007 Aug 2;9(16):3097-9. Epub 2007 Jul 6.

PMID:
17616143
17.
18.

Ir-catalyzed almost perfect enantioselective synthesis of helical polyaryls based on an axially-chiral sequence.

Shibata T, Tsuchikama K.

Chem Commun (Camb). 2005 Dec 28;(48):6017-9. Epub 2005 Nov 4.

PMID:
16333513

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