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Clinical and virulence factors related to the 30-day mortality of Klebsiella pneumoniae bacteremia at a tertiary hospital: a case-control study.

Namikawa H, Niki M, Niki M, Yamada K, Nakaie K, Sakiyama A, Oinuma KI, Tsubouchi T, Tochino Y, Takemoto Y, Kaneko Y, Shuto T, Kakeya H.

Eur J Clin Microbiol Infect Dis. 2019 Dec;38(12):2291-2297. doi: 10.1007/s10096-019-03676-y. Epub 2019 Oct 11.


Telemetered common marmosets is useful for the assessment of electrocardiogram parameters changes induced by multiple cardiac ion channel inhibitors.

Watanabe K, Tsubouchi T, Yamada T, Hinoi E, Miyawaki I.

J Toxicol Sci. 2019;44(7):441-457. doi: 10.2131/jts.44.441.


Clinical characteristics of bacteremia caused by hypermucoviscous Klebsiella pneumoniae at a tertiary hospital.

Namikawa H, Yamada K, Sakiyama A, Imoto W, Yamairi K, Shibata W, Yoshii N, Niki M, Nakaie K, Oinuma KI, Tsubouchi T, Niki M, Tochino Y, Takemoto Y, Kaneko Y, Shuto T, Kakeya H.

Diagn Microbiol Infect Dis. 2019 Sep;95(1):84-88. doi: 10.1016/j.diagmicrobio.2019.04.008. Epub 2019 Apr 26.


Discovery of anti-mucoviscous activity of rifampicin and its potential as a candidate antivirulence agent against hypervirulent Klebsiella pneumoniae.

Namikawa H, Oinuma KI, Sakiyama A, Tsubouchi T, Tahara YO, Yamada K, Niki M, Takemoto Y, Miyata M, Kaneko Y, Shuto T, Kakeya H.

Int J Antimicrob Agents. 2019 Aug;54(2):167-175. doi: 10.1016/j.ijantimicag.2019.05.018. Epub 2019 Jun 5.


Molecular and epidemiological analysis of IMP-1 metallo-β-lactamase-producing Klebsiella pneumoniae in a tertiary care hospital in Japan.

Yamakawa H, Kosai K, Akamatsu N, Matsuda J, Kaku N, Uno N, Morinaga Y, Hasegawa H, Tsubouchi T, Kaneko Y, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

J Infect Chemother. 2019 Apr;25(4):240-246. doi: 10.1016/j.jiac.2018.11.012. Epub 2019 Jan 2.


The effect of beam shape on physical parameters of head and neck simultaneous-integrated boost intensity-modulated radiation therapy.

Tsubouchi T, Yagi M, Sumida I, Tamari K, Seo Y, Ogawa K.

Rep Pract Oncol Radiother. 2018 Sep-Oct;23(5):425-432. doi: 10.1016/j.rpor.2018.08.008. Epub 2018 Sep 4.


Complete Genome Sequence of Sphingobium sp. Strain YG1, a Lignin Model Dimer-Metabolizing Bacterium Isolated from Sediment in Kagoshima Bay, Japan.

Ohta Y, Shimane Y, Nishi S, Ichikawa J, Kurosawa K, Tsubouchi T, Ishii S.

Genome Announc. 2018 Apr 26;6(17). pii: e00267-18. doi: 10.1128/genomeA.00267-18.


Predictive performance of dual modality of computed tomography angiography and intravascular ultrasound for no-reflow phenomenon after percutaneous coronary stenting in stable coronary artery disease.

Okutsu M, Horio T, Tanaka H, Akiyama M, Okimoto N, Tsubouchi T, Kawajiri K, Ohashi Y, Sumitsuji S, Ikari Y.

Heart Vessels. 2018 Oct;33(10):1121-1128. doi: 10.1007/s00380-018-1160-2. Epub 2018 Apr 11.


The in vitro pharmacology and non-clinical cardiovascular safety studies of a novel 5-HT4 receptor agonist, DSP-6952.

Tsubouchi T, Kunimatsu T, Tsujimoto S, Kiyoshi A, Katsura Y, Oku S, Chihara K, Mine Y, Yamada T, Shimizu I, Bando K.

Eur J Pharmacol. 2018 May 5;826:96-105. doi: 10.1016/j.ejphar.2018.02.037. Epub 2018 Mar 1.


Quantitative evaluation of potential irradiation geometries for carbon-ion beam grid therapy.

Tsubouchi T, Henry T, Ureba A, Valdman A, Bassler N, Siegbahn A.

Med Phys. 2018 Mar;45(3):1210-1221. doi: 10.1002/mp.12749. Epub 2018 Jan 25.


Polo is not solo in meiosis.

Argunhan B, Tsubouchi T, Tsubouchi H.

Cell Cycle. 2018;17(3):273-274. doi: 10.1080/15384101.2017.1411435. Epub 2018 Feb 19. No abstract available.


Draft Genome Sequence of the Arsenic-Resistant Bacterium Brevundimonas denitrificans TAR-002T.

Tsubouchi T, Kaneko Y.

Genome Announc. 2017 Nov 22;5(47). pii: e01326-17. doi: 10.1128/genomeA.01326-17.


Exiting prophase I: no clear boundary.

Tsubouchi H, Argunhan B, Tsubouchi T.

Curr Genet. 2018 Apr;64(2):423-427. doi: 10.1007/s00294-017-0771-y. Epub 2017 Oct 25. Review.


Development of an interlaced-crossfiring geometry for proton grid therapy.

Henry T, Bassler N, Ureba A, Tsubouchi T, Valdman A, Siegbahn A.

Acta Oncol. 2017 Nov;56(11):1437-1443. doi: 10.1080/0284186X.2017.1350287. Epub 2017 Aug 22.


Fundamental cell cycle kinases collaborate to ensure timely destruction of the synaptonemal complex during meiosis.

Argunhan B, Leung WK, Afshar N, Terentyev Y, Subramanian VV, Murayama Y, Hochwagen A, Iwasaki H, Tsubouchi T, Tsubouchi H.

EMBO J. 2017 Sep 1;36(17):2488-2509. doi: 10.15252/embj.201695895. Epub 2017 Jul 10.


Significance of integrated in silico transmural ventricular wedge preparation models of human non-failing and failing hearts for safety evaluation of drug candidates.

Kubo T, Ashihara T, Tsubouchi T, Horie M.

J Pharmacol Toxicol Methods. 2017 Jan - Feb;83:30-41. doi: 10.1016/j.vascn.2016.08.007. Epub 2016 Aug 18.


Inhibition of late sodium current attenuates ionic arrhythmia mechanism in ventricular myocytes expressing LaminA-N195K mutation.

Markandeya YS, Tsubouchi T, Hacker TA, Wolff MR, Belardinelli L, Balijepalli RC.

Heart Rhythm. 2016 Nov;13(11):2228-2236. doi: 10.1016/j.hrthm.2016.08.007. Epub 2016 Aug 3.


Shaping meiotic chromosomes with SUMO: a feedback loop controls the assembly of the synaptonemal complex in budding yeast.

Tsubouchi H, Argunhan B, Tsubouchi T.

Microb Cell. 2016 Feb 19;3(3):126-128. doi: 10.15698/mic2016.03.486.


The synaptonemal complex is assembled by a polySUMOylation-driven feedback mechanism in yeast.

Leung WK, Humphryes N, Afshar N, Argunhan B, Terentyev Y, Tsubouchi T, Tsubouchi H.

J Cell Biol. 2015 Nov 23;211(4):785-93. doi: 10.1083/jcb.201506103.


Halarchaeum grantii sp. nov., a moderately acidophilic haloarchaeon isolated from a commercial salt sample.

Shimane Y, Minegishi H, Echigo A, Kamekura M, Itoh T, Ohkuma M, Tsubouchi T, Usui K, Maruyama T, Usami R, Hatada Y.

Int J Syst Evol Microbiol. 2015 Nov;65(11):3830-3835. doi: 10.1099/ijsem.0.000501.


Electrical Retrieval of Living Microorganisms from Cryopreserved Marine Sponges Using a Potential-Controlled Electrode.

Koyama S, Nishi S, Tokuda M, Uemura M, Ishikawa Y, Seya T, Chow S, Ise Y, Hatada Y, Fujiwara Y, Tsubouchi T.

Mar Biotechnol (NY). 2015 Oct;17(5):678-92. doi: 10.1007/s10126-015-9651-y. Epub 2015 Aug 5.


Involvement of flocculin in negative potential-applied ITO electrode adhesion of yeast cells.

Koyama S, Tsubouchi T, Usui K, Uematsu K, Tame A, Nogi Y, Ohta Y, Hatada Y, Kato C, Miwa T, Toyofuku T, Nagahama T, Konishi M, Nagano Y, Abe F.

FEMS Yeast Res. 2015 Sep;15(6). pii: fov064. doi: 10.1093/femsyr/fov064. Epub 2015 Jul 17.


Draft Genome Sequence of Aneurinibacillus tyrosinisolvens LL-002T, Which Possesses Some Pseudouridine Synthases.

Tsubouchi T, Nishi S, Maruyama T, Hatada Y.

Genome Announc. 2015 May 28;3(3). pii: e00529-15. doi: 10.1128/genomeA.00529-15.


Aneurinibacillus tyrosinisolvens sp. nov., a tyrosine-dissolving bacterium isolated from organics- and methane-rich seafloor sediment.

Tsubouchi T, Mori K, Miyamoto N, Fujiwara Y, Kawato M, Shimane Y, Usui K, Tokuda M, Uemura M, Tame A, Uematsu K, Maruyama T, Hatada Y.

Int J Syst Evol Microbiol. 2015 Jun;65(Pt 6):1999-2005. doi: 10.1099/ijs.0.000213. Epub 2015 Mar 26.


Draft Genome Sequence of Novosphingobium sp. Strain MBES04, Isolated from Sunken Wood from Suruga Bay, Japan.

Ohta Y, Nishi S, Kobayashi K, Tsubouchi T, Iida K, Tanizaki A, Kurosawa K, Adachi A, Nishihara M, Sato R, Hasegawa R, Hatada Y.

Genome Announc. 2015 Jan 15;3(1). pii: e01373-14. doi: 10.1128/genomeA.01373-14.


Brevundimonas denitrificans sp. nov., a denitrifying bacterium isolated from deep subseafloor sediment.

Tsubouchi T, Koyama S, Mori K, Shimane Y, Usui K, Tokuda M, Tame A, Uematsu K, Maruyama T, Hatada Y.

Int J Syst Evol Microbiol. 2014 Nov;64(Pt 11):3709-16. doi: 10.1099/ijs.0.067199-0. Epub 2014 Aug 8.


High frequency of phylogenetically diverse reductive dehalogenase-homologous genes in deep subseafloor sedimentary metagenomes.

Kawai M, Futagami T, Toyoda A, Takaki Y, Nishi S, Hori S, Arai W, Tsubouchi T, Morono Y, Uchiyama I, Ito T, Fujiyama A, Inagaki F, Takami H.

Front Microbiol. 2014 Mar 3;5:80. doi: 10.3389/fmicb.2014.00080. eCollection 2014.


Draft Genome Sequence of Loktanella cinnabarina LL-001T, Isolated from Deep-Sea Floor Sediment.

Nishi S, Tsubouchi T, Takaki Y, Koyanagi R, Satoh N, Maruyama T, Hatada Y.

Genome Announc. 2013 Nov 14;1(6). pii: e00927-13. doi: 10.1128/genomeA.00927-13.


Draft Genome Sequence of the Dimorphic Prosthecate Bacterium Brevundimonas abyssalis TAR-001T.

Tsubouchi T, Nishi S, Usui K, Shimane Y, Takaki Y, Maruyama T, Hatada Y.

Genome Announc. 2013 Oct 17;1(5). pii: e00826-13. doi: 10.1128/genomeA.00826-13.


Thalassospira alkalitolerans sp. nov. and Thalassospira mesophila sp. nov., isolated from a decaying bamboo sunken in the marine environment, and emended description of the genus Thalassospira.

Tsubouchi T, Ohta Y, Haga T, Usui K, Shimane Y, Mori K, Tanizaki A, Adachi A, Kobayashi K, Yukawa K, Takagi E, Tame A, Uematsu K, Maruyama T, Hatada Y.

Int J Syst Evol Microbiol. 2014 Jan;64(Pt 1):107-15. doi: 10.1099/ijs.0.056028-0. Epub 2013 Sep 10.


Direct and indirect control of the initiation of meiotic recombination by DNA damage checkpoint mechanisms in budding yeast.

Argunhan B, Farmer S, Leung WK, Terentyev Y, Humphryes N, Tsubouchi T, Toyoizumi H, Tsubouchi H.

PLoS One. 2013 Jun 10;8(6):e65875. doi: 10.1371/journal.pone.0065875. Print 2013.


Molecular biological and isotopic biogeochemical prognoses of the nitrification-driven dynamic microbial nitrogen cycle in hadopelagic sediments.

Nunoura T, Nishizawa M, Kikuchi T, Tsubouchi T, Hirai M, Koide O, Miyazaki J, Hirayama H, Koba K, Takai K.

Environ Microbiol. 2013 Nov;15(11):3087-107. doi: 10.1111/1462-2920.12152. Epub 2013 May 29.


Reprogramming and the pluripotent stem cell cycle.

Tsubouchi T, Fisher AG.

Curr Top Dev Biol. 2013;104:223-41. doi: 10.1016/B978-0-12-416027-9.00007-3. Review.


Attachment and detachment of living microorganisms using a potential-controlled electrode.

Koyama S, Konishi MA, Ohta Y, Miwa T, Hatada Y, Toyofuku T, Maruyama T, Nogi Y, Kato C, Tsubouchi T.

Mar Biotechnol (NY). 2013 Aug;15(4):461-75. doi: 10.1007/s10126-013-9495-2. Epub 2013 Feb 19.


DNA synthesis is required for reprogramming mediated by stem cell fusion.

Tsubouchi T, Soza-Ried J, Brown K, Piccolo FM, Cantone I, Landeira D, Bagci H, Hochegger H, Merkenschlager M, Fisher AG.

Cell. 2013 Feb 14;152(4):873-83. doi: 10.1016/j.cell.2013.01.012.


Brevundimonas abyssalis sp. nov., a dimorphic prosthecate bacterium isolated from deep-subsea floor sediment.

Tsubouchi T, Shimane Y, Usui K, Shimamura S, Mori K, Hiraki T, Tame A, Uematsu K, Maruyama T, Hatada Y.

Int J Syst Evol Microbiol. 2013 Jun;63(Pt 6):1987-94. doi: 10.1099/ijs.0.043364-0. Epub 2012 Oct 5.


Polycladomyces abyssicola gen. nov., sp. nov., a thermophilic filamentous bacterium isolated from hemipelagic sediment.

Tsubouchi T, Shimane Y, Mori K, Usui K, Hiraki T, Tame A, Uematsu K, Maruyama T, Hatada Y.

Int J Syst Evol Microbiol. 2013 Jun;63(Pt 6):1972-81. doi: 10.1099/ijs.0.043596-0. Epub 2012 Sep 28.


The Hadal Amphipod Hirondellea gigas possessing a unique cellulase for digesting wooden debris buried in the deepest seafloor.

Kobayashi H, Hatada Y, Tsubouchi T, Nagahama T, Takami H.

PLoS One. 2012;7(8):e42727. doi: 10.1371/journal.pone.0042727. Epub 2012 Aug 15.


Loktanella cinnabarina sp. nov., isolated from a deep subseafloor sediment, and emended description of the genus Loktanella.

Tsubouchi T, Shimane Y, Mori K, Miyazaki M, Tame A, Uematsu K, Maruyama T, Hatada Y.

Int J Syst Evol Microbiol. 2013 Apr;63(Pt 4):1390-5. doi: 10.1099/ijs.0.043174-0. Epub 2012 Jul 27.


Using heterokaryons to understand pluripotency and reprogramming.

Piccolo FM, Pereira CF, Cantone I, Brown K, Tsubouchi T, Soza-Ried J, Merkenschlager M, Fisher AG.

Philos Trans R Soc Lond B Biol Sci. 2011 Aug 12;366(1575):2260-5. doi: 10.1098/rstb.2011.0004. Review.


ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.

Pereira CF, Piccolo FM, Tsubouchi T, Sauer S, Ryan NK, Bruno L, Landeira D, Santos J, Banito A, Gil J, Koseki H, Merkenschlager M, Fisher AG.

Cell Stem Cell. 2010 Jun 4;6(6):547-56. doi: 10.1016/j.stem.2010.04.013.


Initiation of meiotic chromosome synapsis at centromeres in budding yeast.

Tsubouchi T, Macqueen AJ, Roeder GS.

Genes Dev. 2008 Nov 15;22(22):3217-26. doi: 10.1101/gad.1709408.


Global analysis of the meiotic crossover landscape.

Chen SY, Tsubouchi T, Rockmill B, Sandler JS, Richards DR, Vader G, Hochwagen A, Roeder GS, Fung JC.

Dev Cell. 2008 Sep;15(3):401-15. doi: 10.1016/j.devcel.2008.07.006. Epub 2008 Aug 7.


Swallowing disorder and inhibition of cough reflex induced by atropine sulfate in conscious dogs.

Tsubouchi T, Tsujimoto S, Sugimoto S, Katsura Y, Mino T, Seki T.

J Pharmacol Sci. 2008 Mar;106(3):452-9. Epub 2008 Mar 12.


Involvement of the arginine repressor in lysine biosynthesis of Thermus thermophilus.

Fujiwara K, Tsubouchi T, Kuzuyama T, Nishiyama M.

Microbiology. 2006 Dec;152(Pt 12):3585-3594. doi: 10.1099/mic.0.29222-0.


Lower critical solution temperature type of phase separation in aqueous mixture of polyelectrolytes.

Tsubouchi T, Nishida K, Kanaya T.

Colloids Surf B Biointerfaces. 2007 Apr 15;56(1-2):265-9. Epub 2006 Nov 10.


A synaptonemal complex protein promotes homology-independent centromere coupling.

Tsubouchi T, Roeder GS.

Science. 2005 May 6;308(5723):870-3.


Leader peptide-mediated transcriptional attenuation of lysine biosynthetic gene cluster in Thermus thermophilus.

Tsubouchi T, Mineki R, Taka H, Kaga N, Murayama K, Nishiyama C, Yamane H, Kuzuyama T, Nishiyama M.

J Biol Chem. 2005 May 6;280(18):18511-6. Epub 2005 Mar 7.


Etizolam and benzodiazepine induced blepharospasm.

Wakakura M, Tsubouchi T, Inouye J.

J Neurol Neurosurg Psychiatry. 2004 Mar;75(3):506-7. No abstract available.

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