Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 78

1.

Regulation of immune responsiveness in vivo by disrupting an early T-cell signaling event using a cell-permeable peptide.

Guimond DM, Cam NR, Hirve N, Duan W, Lambris JD, Croft M, Tsoukas CD.

PLoS One. 2013 May 7;8(5):e63645. doi: 10.1371/journal.pone.0063645. Print 2013.

2.

A conserved motif in the ITK PH-domain is required for phosphoinositide binding and TCR signaling but dispensable for adaptor protein interactions.

Hirve N, Levytskyy RM, Rigaud S, Guimond DM, Zal T, Sauer K, Tsoukas CD.

PLoS One. 2012;7(9):e45158. doi: 10.1371/journal.pone.0045158. Epub 2012 Sep 18.

3.

In Vivo Consequences of Disrupting SH3-Mediated Interactions of the Inducible T-Cell Kinase.

Levytskyy RM, Hirve N, Guimond DM, Min L, Andreotti AH, Tsoukas CD.

J Signal Transduct. 2012;2012:694386. doi: 10.1155/2012/694386. Epub 2012 May 9.

4.

Itk: the rheostat of the T cell response.

Grasis JA, Tsoukas CD.

J Signal Transduct. 2011;2011:297868. doi: 10.1155/2011/297868. Epub 2011 Apr 7.

5.

In vivo significance of ITK-SLP-76 interaction in cytokine production.

Grasis JA, Guimond DM, Cam NR, Herman K, Magotti P, Lambris JD, Tsoukas CD.

Mol Cell Biol. 2010 Jul;30(14):3596-609. doi: 10.1128/MCB.01657-09. Epub 2010 May 10.

6.

Navigating the leukocyte signaling maze guided by Ariadne's thread.

Altman A, Koretzky GA, Tsoukas CD.

Nat Immunol. 2009 Nov;10(11):1134-6. doi: 10.1038/ni1109-1134.

PMID:
19841642
7.

Positive regulation of Itk PH domain function by soluble IP4.

Huang YH, Grasis JA, Miller AT, Xu R, Soonthornvacharin S, Andreotti AH, Tsoukas CD, Cooke MP, Sauer K.

Science. 2007 May 11;316(5826):886-9. Epub 2007 Apr 5.

8.

Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway.

Bueno C, Lemke CD, Criado G, Baroja ML, Ferguson SS, Rahman AK, Tsoukas CD, McCormick JK, Madrenas J.

Immunity. 2006 Jul;25(1):67-78.

9.

Inducible T cell tyrosine kinase (ITK): structural requirements and actin polymerization.

Tsoukas CD, Grasis JA, Browne CD, Ching KA.

Adv Exp Med Biol. 2006;584:29-41. Review. No abstract available.

PMID:
16802597
10.
11.

Itk/Emt: a link between T cell antigen receptor-mediated Ca2+ events and cytoskeletal reorganization.

Tsoukas CD, Grasis JA, Ching KA, Kawakami Y, Kawakami T.

Trends Immunol. 2001 Jan;22(1):17-20. Review.

PMID:
11286686
12.
13.

TCR/CD3-Induced activation and binding of Emt/Itk to linker of activated T cell complexes: requirement for the Src homology 2 domain.

Ching KA, Grasis JA, Tailor P, Kawakami Y, Kawakami T, Tsoukas CD.

J Immunol. 2000 Jul 1;165(1):256-62.

14.

Activation of heterotrimeric GTP-binding proteins upon TCR/CD3 engagement.

Tsoukas CD, Stanners J, Ching KA.

Methods Mol Biol. 2000;134:319-24. No abstract available.

PMID:
10730270
15.

Emt/Itk associates with activated TCR complexes: role of the pleckstrin homology domain.

Ching KA, Kawakami Y, Kawakami T, Tsoukas CD.

J Immunol. 1999 Dec 1;163(11):6006-13.

16.

Inhibition of TCR/CD3-mediated signaling by a mutant of the hematopoietically expressed G16 GTP-binding protein.

Zhou J, Stanners J, Kabouridis P, Han H, Tsoukas CD.

Eur J Immunol. 1998 May;28(5):1645-55.

17.

CD81 expressed on human thymocytes mediates integrin activation and interleukin 2-dependent proliferation.

Todd SC, Lipps SG, Crisa L, Salomon DR, Tsoukas CD.

J Exp Med. 1996 Nov 1;184(5):2055-60.

18.

EBV induces proliferation of immature human thymocytes in an IL-2-mediated response.

Todd SC, Tsoukas CD.

J Immunol. 1996 Jun 1;156(11):4217-23.

PMID:
8666790
19.

Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling.

Stanners J, Kabouridis PS, McGuire KL, Tsoukas CD.

J Biol Chem. 1995 Dec 22;270(51):30635-42.

20.

Expression of GTP-binding protein alpha subunits in human thymocytes.

Kabouridis PS, Waters ST, Escobar S, Stanners J, Tsoukas CD.

Mol Cell Biochem. 1995 Mar 9;144(1):45-51.

PMID:
7791744
21.

Characterization of a 70-kDa, EBV gp350/220-binding protein on HSB-2 T cells.

Hedrick JA, Lao Z, Lipps SG, Wang Y, Todd SC, Lambris JD, Tsoukas CD.

J Immunol. 1994 Nov 15;153(10):4418-26.

PMID:
7963519
22.

CD1+ human thymocytes proliferate in response to superantigen staphylococcal enterotoxin B1.

Todd SC, Baccala R, Hedrick JA, Theofilopoulos AN, Tsoukas CD.

J Immunol. 1994 Sep 1;153(5):2038-45.

PMID:
7519639
23.

Characterization of the EBV/C3d receptor on the human Jurkat T cell line: evidence for a novel transcript.

Sinha SK, Todd SC, Hedrick JA, Speiser CL, Lambris JD, Tsoukas CD.

J Immunol. 1993 Jun 15;150(12):5311-20.

PMID:
8390533
24.

Expression of EBV/C3d receptors on T cells: biological significance.

Tsoukas CD, Lambris JD.

Immunol Today. 1993 Feb;14(2):56-9. Review.

PMID:
8383497
25.

Interaction between Epstein-Barr virus and a T cell line (HSB-2) via a receptor phenotypically distinct from complement receptor type 2.

Hedrick JA, Watry D, Speiser C, O'Donnell P, Lambris JD, Tsoukas CD.

Eur J Immunol. 1992 May;22(5):1123-31.

PMID:
1315687
26.

Evidence for multiple sites of interaction in C3 for complement receptor type 2 (C3d/EBV receptor, CD21).

Esparza I, Becherer JD, Alsenz J, De la Hera A, Lao Z, Tsoukas CD, Lambris JD.

Eur J Immunol. 1991 Nov;21(11):2829-38.

PMID:
1834472
27.

Infection of human thymocytes by Epstein-Barr virus.

Watry D, Hedrick JA, Siervo S, Rhodes G, Lamberti JJ, Lambris JD, Tsoukas CD.

J Exp Med. 1991 Apr 1;173(4):971-80.

28.
29.

Cholera toxin inhibits resting human T cell activation via a cAMP-independent pathway.

Anderson DL, Tsoukas CD.

J Immunol. 1989 Dec 1;143(11):3647-52.

PMID:
2555413
30.

Inhibition of interleukin-1 production by 1,25-dihydroxyvitamin D3.

Tsoukas CD, Watry D, Escobar SS, Provvedini DM, Dinarello CA, Hustmyer FG, Manolagas SC.

J Clin Endocrinol Metab. 1989 Jul;69(1):127-33.

PMID:
2525134
31.

Impairment in T-lymphocyte responses during early infection with the human immunodeficiency virus.

Bentin J, Tsoukas CD, McCutchan JA, Spector SA, Richman DD, Vaughan JH.

J Clin Immunol. 1989 Mar;9(2):159-68.

PMID:
2785531
32.

Expression of CR2/EBV receptors on human thymocytes detected by monoclonal antibodies.

Tsoukas CD, Lambris JD.

Eur J Immunol. 1988 Aug;18(8):1299-302.

PMID:
2970972
33.

T cell proliferation induced by anti-CD3 antibodies: requirement for a T-T cell interaction.

Bentin J, Vaughan JH, Tsoukas CD.

Eur J Immunol. 1988 Apr;18(4):627-32.

PMID:
2966741
34.

Structural and functional characteristics of the CD3 (T3) molecular complex on human thymocytes.

Tsoukas CD, Landgraf B, Bentin J, Lamberti JF, Carson DA, Vaughan JH.

J Immunol. 1987 Jun 1;138(11):3885-90.

PMID:
3108378
35.

1 alpha,25-Dihydroxyvitamin D3 receptors in human thymic and tonsillar lymphocytes.

Provvedini DM, Rulot CM, Sobol RE, Tsoukas CD, Manolagas SC.

J Bone Miner Res. 1987 Jun;2(3):239-47.

PMID:
2843004
36.

Effects of recombinant human interferons on rheumatoid arthritis B lymphocytes activated by Epstein-Barr virus.

Lotz M, Tsoukas CD, Curd JG, Carson DA, Vaughan JH.

J Rheumatol. 1987 Feb;14(1):42-5.

PMID:
3033238
37.

1,25-Dihydroxyvitamin D3 receptors in lymphocytes from patients with rheumatoid arthritis.

Manolagas SC, Werntz DA, Tsoukas CD, Provvedini DM, Vaughan JH.

J Lab Clin Med. 1986 Dec;108(6):596-600.

PMID:
3023512
38.

Inhibition of anti-CD3 (T3) antibody-induced activation of T cells by cyclosporine.

Bentin J, Carson DA, Vaughan JH, Tsoukas CD.

Transplantation. 1986 Sep;42(3):317-20. No abstract available.

PMID:
3092413
39.

Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies.

Lotz M, Tsoukas CD, Robinson CA, Dinarello CA, Carson DA, Vaughan JH.

J Clin Invest. 1986 Sep;78(3):713-21.

40.

The antiproliferative effect of calcitriol on human peripheral blood mononuclear cells.

Manolagas SC, Provvedini DM, Murray EJ, Tsoukas CD, Deftos LJ.

J Clin Endocrinol Metab. 1986 Aug;63(2):394-400.

PMID:
3013918
42.

Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans.

Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH.

J Immunol. 1986 May 15;136(10):3636-42.

PMID:
3009608
43.

1 alpha,25-Dihydroxyvitamin D3-binding macromolecules in human B lymphocytes: effects on immunoglobulin production.

Provvedini DM, Tsoukas CD, Deftos LJ, Manolagas SC.

J Immunol. 1986 Apr 15;136(8):2734-40.

PMID:
3007606
44.

Release of lymphokines following Epstein-Barr virus infection in vitro of blood lymphocytes from patients with autoimmune diseases.

Lotz M, Tsoukas CD, Hench PK, Carson DA, Vaughan JH.

Trans Assoc Am Physicians. 1986;99:114-24. No abstract available.

PMID:
2440173
45.

Interactions of 1,25-dihydroxyvitamin D3 and the immune system.

Manolagas SC, Provvedini DM, Tsoukas CD.

Mol Cell Endocrinol. 1985 Dec;43(2-3):113-22. Review.

PMID:
3000847
46.

Characterization of Epstein-Barr virus-specific T-cell hybridomas derived from infectious mononucleosis.

Valentine MA, Tsoukas CD, Vaughan JH, Carson DA.

Clin Immunol Immunopathol. 1985 Oct;37(1):56-62.

PMID:
2992857
47.

Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes.

Tsoukas CD, Landgraf B, Bentin J, Valentine M, Lotz M, Vaughan JH, Carson DA.

J Immunol. 1985 Sep;135(3):1719-23.

PMID:
3926881
48.

Phytohemagglutinin binds to the 20-kDa molecule of the T3 complex.

Valentine MA, Tsoukas CD, Rhodes G, Vaughan JH, Carson DA.

Eur J Immunol. 1985 Aug;15(8):851-4.

PMID:
3161747
49.

Regulation of immunoglobulin secretion by factor H of human complement.

Tsokos GC, Inghirami G, Tsoukas CD, Balow JE, Lambris JD.

Immunology. 1985 Jul;55(3):419-26.

50.

Regulation of Epstein-Barr virus infection by recombinant interferons. Selected sensitivity to interferon-gamma.

Lotz M, Tsoukas CD, Fong S, Carson DA, Vaughan JH.

Eur J Immunol. 1985 May;15(5):520-5.

PMID:
2581792

Supplemental Content

Loading ...
Support Center