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Items: 1 to 50 of 64

1.

Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC.

Patrick MT, Stuart PE, Raja K, Chi S, He Z, Voorhees JJ, Tejasvi T, Gudjonsson JE, Kahlenberg JM, Chandran V, Rahman P, Gladman DD, Nair RP, Elder JT, Tsoi LC.

Front Genet. 2019 Apr 11;10:304. doi: 10.3389/fgene.2019.00304. eCollection 2019.

2.

2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells.

Le ST, Merleev AA, Luxardi G, Shimoda M, Adamopoulos IE, Tsoi LC, Wang JZ, Alexanian C, Raychaudhuri SP, Hwang ST, Gudjonsson J, Marusina AI, Maverakis E.

Front Immunol. 2019 Apr 4;10:589. doi: 10.3389/fimmu.2019.00589. eCollection 2019.

3.

The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.

Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.

JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18.

4.

Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis.

Teague HL, Varghese NJ, Tsoi LC, Dey AK, Garshick MS, Silverman JI, Baumer Y, Harrington CL, Stempinski E, Elnabawi YA, Dagur PK, Cui K, Tunc I, Seifuddin F, Joshi AA, Stansky E, Purmalek MM, Rodante JA, Keel A, Aridi TZ, Carmona-Rivera C, Sanda GE, Chen MY, Pirooznia M, McCoy JP Jr, Gelfand JM, Zhao K, Gudjonsson JE, Playford MP, Kaplan MJ, Berger JS, Mehta NN.

JACC Basic Transl Sci. 2019 Feb 25;4(1):1-14. doi: 10.1016/j.jacbts.2018.10.008. eCollection 2019 Feb.

5.

Making New Connections-Chromosome Conformation Capture for Identification of Disease-Associated Target Genes.

Patrick MT, Tsoi LC, Gudjonsson JE.

J Invest Dermatol. 2019 Mar;139(3):514-517. doi: 10.1016/j.jid.2018.11.026.

PMID:
30797317
6.

Hypersensitive IFN Responses in Lupus Keratinocytes Reveal Key Mechanistic Determinants in Cutaneous Lupus.

Tsoi LC, Hile GA, Berthier CC, Sarkar MK, Reed TJ, Liu J, Uppala R, Patrick M, Raja K, Xing X, Xing E, He K, Gudjonsson JE, Kahlenberg JM.

J Immunol. 2019 Apr 1;202(7):2121-2130. doi: 10.4049/jimmunol.1800650. Epub 2019 Feb 11.

PMID:
30745462
7.

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.

Budu-Aggrey A, Brumpton B, Tyrrell J, Watkins S, Modalsli EH, Celis-Morales C, Ferguson LD, Vie GÅ, Palmer T, Fritsche LG, Løset M, Nielsen JB, Zhou W, Tsoi LC, Wood AR, Jones SE, Beaumont R, Saunes M, Romundstad PR, Siebert S, McInnes IB, Elder JT, Davey Smith G, Frayling TM, Åsvold BO, Brown SJ, Sattar N, Paternoster L.

PLoS Med. 2019 Jan 31;16(1):e1002739. doi: 10.1371/journal.pmed.1002739. eCollection 2019 Jan.

8.

Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis.

Tsoi LC, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell WR, Sarkar MK, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White BE, Getsios S, Harms PW, Maverakis E, Elder JT, Franke A, Gudjonsson JE, Weidinger S.

J Invest Dermatol. 2019 Jan 11. pii: S0022-202X(19)30007-7. doi: 10.1016/j.jid.2018.12.018. [Epub ahead of print]

PMID:
30641038
9.

A Transethnic Mendelian Randomization Study Identifies Causality of Obesity on Risk of Psoriasis.

Ogawa K, Stuart PE, Tsoi LC, Suzuki K, Nair RP, Mochizuki H, Elder JT, Okada Y.

J Invest Dermatol. 2019 Jun;139(6):1397-1400. doi: 10.1016/j.jid.2018.11.023. Epub 2018 Dec 5. No abstract available.

10.

Neutrophil Extracellular Traps Induce Human Th17 Cells: Effect of Psoriasis-Associated TRAF3IP2 Genotype.

Lambert S, Hambro CA, Johnston A, Stuart PE, Tsoi LC, Nair RP, Elder JT.

J Invest Dermatol. 2019 Jun;139(6):1245-1253. doi: 10.1016/j.jid.2018.11.021. Epub 2018 Dec 5.

PMID:
30528823
11.

Novel cytokine and chemokine markers of hidradenitis suppurativa reflect chronic inflammation and itch.

Vossen ARJV, van der Zee HH, Tsoi LC, Xing X, Devalaraja M, Gudjonsson JE, Prens EP.

Allergy. 2019 Mar;74(3):631-634. doi: 10.1111/all.13665. Epub 2018 Dec 10. No abstract available.

PMID:
30421795
12.

Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach.

Patrick MT, Raja K, Miller K, Sotzen J, Gudjonsson JE, Elder JT, Tsoi LC.

J Invest Dermatol. 2019 Mar;139(3):683-691. doi: 10.1016/j.jid.2018.09.018. Epub 2018 Oct 17.

13.

Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.

Tylee DS, Sun J, Hess JL, Tahir MA, Sharma E, Malik R, Worrall BB, Levine AJ, Martinson JJ, Nejentsev S, Speed D, Fischer A, Mick E, Walker BR, Crawford A, Grant SFA, Polychronakos C, Bradfield JP, Sleiman PMA, Hakonarson H, Ellinghaus E, Elder JT, Tsoi LC, Trembath RC, Barker JN, Franke A, Dehghan A; 23 and Me Research Team; Inflammation Working Group of the CHARGE Consortium; METASTROKE Consortium of the International Stroke Genetics Consortium; Netherlands Twin Registry; neuroCHARGE Working Group; Obsessive Compulsive and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, Faraone SV, Glatt SJ.

Am J Med Genet B Neuropsychiatr Genet. 2018 Oct;177(7):641-657. doi: 10.1002/ajmg.b.32652. Epub 2018 Oct 16.

PMID:
30325587
14.

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients.

Patrick MT, Stuart PE, Raja K, Gudjonsson JE, Tejasvi T, Yang J, Chandran V, Das S, Callis-Duffin K, Ellinghaus E, Enerbäck C, Esko T, Franke A, Kang HM, Krueger GG, Lim HW, Rahman P, Rosen CF, Weidinger S, Weichenthal M, Wen X, Voorhees JJ, Abecasis GR, Gladman DD, Nair RP, Elder JT, Tsoi LC.

Nat Commun. 2018 Oct 9;9(1):4178. doi: 10.1038/s41467-018-06672-6.

15.

Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa.

Sarkar MK, Hile GA, Tsoi LC, Xing X, Liu J, Liang Y, Berthier CC, Swindell WR, Patrick MT, Shao S, Tsou PS, Uppala R, Beamer MA, Srivastava A, Bielas SL, Harms PW, Getsios S, Elder JT, Voorhees JJ, Gudjonsson JE, Kahlenberg JM.

Ann Rheum Dis. 2018 Nov;77(11):1653-1664. doi: 10.1136/annrheumdis-2018-213197. Epub 2018 Jul 18.

PMID:
30021804
16.

Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A.

Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis E.

JCI Insight. 2018 Jul 12;3(13). pii: 120682. doi: 10.1172/jci.insight.120682.

17.

The psoriasis-protective TYK2 I684S variant impairs IL-12 stimulated pSTAT4 response in skin-homing CD4+ and CD8+ memory T-cells.

Enerbäck C, Sandin C, Lambert S, Zawistowski M, Stuart PE, Verma D, Tsoi LC, Nair RP, Johnston A, Elder JT.

Sci Rep. 2018 May 4;8(1):7043. doi: 10.1038/s41598-018-25282-2.

18.

Research Techniques Made Simple: Using Genome-Wide Association Studies to Understand Complex Cutaneous Disorders.

Tsoi LC, Patrick MT, Elder JT.

J Invest Dermatol. 2018 Mar;138(3):e23-e29. doi: 10.1016/j.jid.2018.01.004. Review.

19.

RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature.

Swindell WR, Beamer MA, Sarkar MK, Loftus S, Fullmer J, Xing X, Ward NL, Tsoi LC, Kahlenberg MJ, Liang Y, Gudjonsson JE.

Front Immunol. 2018 Jan 29;9:80. doi: 10.3389/fimmu.2018.00080. eCollection 2018.

20.

Transcriptional determinants of individualized inflammatory responses at anatomically separate sites.

Tsoi LC, Yang J, Liang Y, Sarkar MK, Xing X, Beamer MA, Aphale A, Raja K, Kozlow JH, Getsios S, Voorhees JJ, Kahlenberg JM, Elder JT, Gudjonsson JE.

J Allergy Clin Immunol. 2018 Feb;141(2):805-808. doi: 10.1016/j.jaci.2017.07.054. Epub 2017 Oct 13. No abstract available.

21.

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.

Dand N, Mucha S, Tsoi LC, Mahil SK, Stuart PE, Arnold A, Baurecht H, Burden AD, Callis Duffin K, Chandran V, Curtis CJ, Das S, Ellinghaus D, Ellinghaus E, Enerback C, Esko T, Gladman DD, Griffiths CEM, Gudjonsson JE, Hoffman P, Homuth G, Hüffmeier U, Krueger GG, Laudes M, Lee SH, Lieb W, Lim HW, Löhr S, Mrowietz U, Müller-Nurayid M, Nöthen M, Peters A, Rahman P, Reis A, Reynolds NJ, Rodriguez E, Schmidt CO, Spain SL, Strauch K, Tejasvi T, Voorhees JJ, Warren RB, Weichenthal M, Weidinger S, Zawistowski M, Nair RP, Capon F, Smith CH, Trembath RC, Abecasis GR, Elder JT, Franke A, Simpson MA, Barker JN.

Hum Mol Genet. 2017 Nov 1;26(21):4301-4313. doi: 10.1093/hmg/ddx328.

22.

The Promise of Genomic Studies on Human Diseases: From Basic Science to Clinical Application.

Tsoi LC, Wolf B, Chen YA.

Int J Genomics. 2017;2017:5093167. doi: 10.1155/2017/5093167. Epub 2017 Mar 29. No abstract available.

23.

Simple Analysis of Deposited Gene Expression Datasets for the Non-Bioinformatician: How to Use GEO for Fibrosis Research.

Guo Y, Townsend R, Tsoi LC.

Methods Mol Biol. 2017;1627:511-525. doi: 10.1007/978-1-4939-7113-8_31.

PMID:
28836221
24.

Psoriasis: a mixed autoimmune and autoinflammatory disease.

Liang Y, Sarkar MK, Tsoi LC, Gudjonsson JE.

Curr Opin Immunol. 2017 Dec;49:1-8. doi: 10.1016/j.coi.2017.07.007. Epub 2017 Jul 22. Review.

25.

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.

Niehues H, Tsoi LC, van der Krieken DA, Jansen PAM, Oortveld MAW, Rodijk-Olthuis D, van Vlijmen IMJJ, Hendriks WJAJ, Helder RW, Bouwstra JA, van den Bogaard EH, Stuart PE, Nair RP, Elder JT, Zeeuwen PLJM, Schalkwijk J.

J Invest Dermatol. 2017 Nov;137(11):2380-2388. doi: 10.1016/j.jid.2017.06.003. Epub 2017 Jun 17.

26.
27.

miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis.

Hermann H, Runnel T, Aab A, Baurecht H, Rodriguez E, Magilnick N, Urgard E, Šahmatova L, Prans E, Maslovskaja J, Abram K, Karelson M, Kaldvee B, Reemann P, Haljasorg U, Rückert B, Wawrzyniak P, Weichenthal M, Mrowietz U, Franke A, Gieger C, Barker J, Trembath R, Tsoi LC, Elder JT, Tkaczyk ER, Kisand K, Peterson P, Kingo K, Boldin M, Weidinger S, Akdis CA, Rebane A.

J Invest Dermatol. 2017 Sep;137(9):1945-1954. doi: 10.1016/j.jid.2017.05.012. Epub 2017 Jun 6.

28.

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.

Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S, Zawistowski M, Ellinghaus E, Barker JN, Chandran V, Dand N, Duffin KC, Enerbäck C, Esko T, Franke A, Gladman DD, Hoffmann P, Kingo K, Kõks S, Krueger GG, Lim HW, Metspalu A, Mrowietz U, Mucha S, Rahman P, Reis A, Tejasvi T, Trembath R, Voorhees JJ, Weidinger S, Weichenthal M, Wen X, Eriksson N, Kang HM, Hinds DA, Nair RP, Abecasis GR, Elder JT.

Nat Commun. 2017 May 24;8:15382. doi: 10.1038/ncomms15382.

29.

A rare coding allele in IFIH1 is protective for psoriatic arthritis.

Budu-Aggrey A, Bowes J, Stuart PE, Zawistowski M, Tsoi LC, Nair R, Jadon DR, McHugh N, Korendowych E, Elder JT, Barton A, Raychaudhuri S.

Ann Rheum Dis. 2017 Jul;76(7):1321-1324. doi: 10.1136/annrheumdis-2016-210592. Epub 2017 May 13.

30.

GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states.

Klein RH, Lin Z, Hopkin AS, Gordon W, Tsoi LC, Liang Y, Gudjonsson JE, Andersen B.

PLoS Genet. 2017 Apr 26;13(4):e1006745. doi: 10.1371/journal.pgen.1006745. eCollection 2017 Apr.

31.

The Molecular Revolution in Cutaneous Biology: The Era of Global Transcriptional Analysis.

Johnston A, Sarkar MK, Vrana A, Tsoi LC, Gudjonsson JE.

J Invest Dermatol. 2017 May;137(5):e87-e91. doi: 10.1016/j.jid.2016.02.817. Review.

32.

A Review of Recent Advancement in Integrating Omics Data with Literature Mining towards Biomedical Discoveries.

Raja K, Patrick M, Gao Y, Madu D, Yang Y, Tsoi LC.

Int J Genomics. 2017;2017:6213474. doi: 10.1155/2017/6213474. Epub 2017 Feb 26. Review.

33.

Dual Role of Act1 in Keratinocyte Differentiation and Host Defense: TRAF3IP2 Silencing Alters Keratinocyte Differentiation and Inhibits IL-17 Responses.

Lambert S, Swindell WR, Tsoi LC, Stoll SW, Elder JT.

J Invest Dermatol. 2017 Jul;137(7):1501-1511. doi: 10.1016/j.jid.2016.12.032. Epub 2017 Mar 6.

34.

Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation.

Sarkar MK, Kaplan N, Tsoi LC, Xing X, Liang Y, Swindell WR, Hoover P, Aravind M, Baida G, Clark M, Voorhees JJ, Nair RP, Elder JT, Budunova I, Getsios S, Gudjonsson JE.

J Invest Dermatol. 2017 Jul;137(7):1474-1483. doi: 10.1016/j.jid.2017.02.972. Epub 2017 Mar 1. Erratum in: J Invest Dermatol. 2017 Dec;137(12):2665.

35.

A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases.

Liang Y, Tsoi LC, Xing X, Beamer MA, Swindell WR, Sarkar MK, Berthier CC, Stuart PE, Harms PW, Nair RP, Elder JT, Voorhees JJ, Kahlenberg JM, Gudjonsson JE.

Nat Immunol. 2017 Feb;18(2):152-160. doi: 10.1038/ni.3643. Epub 2016 Dec 19.

36.

Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.

Zhou F, Shen C, Xu J, Gao J, Zheng X, Ko R, Dou J, Cheng Y, Zhu C, Xu S, Tang X, Zuo X, Yin X, Cui Y, Sun L, Tsoi LC, Hsu YH, Yang S, Zhang X.

Clin Epigenetics. 2016 Dec 5;8:131. doi: 10.1186/s13148-016-0297-z. eCollection 2016.

37.

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

Prins BP, Abbasi A, Wong A, Vaez A, Nolte I, Franceschini N, Stuart PE, Guterriez Achury J, Mistry V, Bradfield JP, Valdes AM, Bras J, Shatunov A; PAGE Consortium; International Stroke Genetics Consortium; Systemic Sclerosis consortium; Treat OA consortium; DIAGRAM Consortium; CARDIoGRAMplusC4D Consortium; ALS consortium; International Parkinson’s Disease Genomics Consortium; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; CKDGen consortium; GERAD1 Consortium; International Consortium for Blood Pressure; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Inflammation Working Group of the CHARGE Consortium, Lu C, Han B, Raychaudhuri S, Bevan S, Mayes MD, Tsoi LC, Evangelou E, Nair RP, Grant SF, Polychronakos C, Radstake TR, van Heel DA, Dunstan ML, Wood NW, Al-Chalabi A, Dehghan A, Hakonarson H, Markus HS, Elder JT, Knight J, Arking DE, Spector TD, Koeleman BP, van Duijn CM, Martin J, Morris AP, Weersma RK, Wijmenga C, Munroe PB, Perry JR, Pouget JG, Jamshidi Y, Snieder H, Alizadeh BZ.

PLoS Med. 2016 Jun 21;13(6):e1001976. doi: 10.1371/journal.pmed.1001976. eCollection 2016 Jun.

38.

Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.

Stuart PE, Nair RP, Tsoi LC, Tejasvi T, Das S, Kang HM, Ellinghaus E, Chandran V, Callis-Duffin K, Ike R, Li Y, Wen X, Enerbäck C, Gudjonsson JE, Kõks S, Kingo K, Esko T, Mrowietz U, Reis A, Wichmann HE, Gieger C, Hoffmann P, Nöthen MM, Winkelmann J, Kunz M, Moreta EG, Mease PJ, Ritchlin CT, Bowcock AM, Krueger GG, Lim HW, Weidinger S, Weichenthal M, Voorhees JJ, Rahman P, Gregersen PK, Franke A, Gladman DD, Abecasis GR, Elder JT.

Am J Hum Genet. 2015 Dec 3;97(6):816-36. doi: 10.1016/j.ajhg.2015.10.019. Epub 2015 Nov 28.

39.

Correction: Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools.

Ding J, Sidore C, Butler TJ, Wing MK, Qian Y, Meirelles O, Busonero F, Tsoi LC, Maschio A, Angius A, Kang HM, Nagaraja R, Cucca F, Abecasis GR, Schlessinger D.

PLoS Genet. 2015 Sep 29;11(9):e1005549. doi: 10.1371/journal.pgen.1005549. eCollection 2015 Sep. No abstract available.

40.

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases.

Lenz TL, Deutsch AJ, Han B, Hu X, Okada Y, Eyre S, Knapp M, Zhernakova A, Huizinga TW, Abecasis G, Becker J, Boeckxstaens GE, Chen WM, Franke A, Gladman DD, Gockel I, Gutierrez-Achury J, Martin J, Nair RP, Nöthen MM, Onengut-Gumuscu S, Rahman P, Rantapää-Dahlqvist S, Stuart PE, Tsoi LC, van Heel DA, Worthington J, Wouters MM, Klareskog L, Elder JT, Gregersen PK, Schumacher J, Rich SS, Wijmenga C, Sunyaev SR, de Bakker PI, Raychaudhuri S.

Nat Genet. 2015 Sep;47(9):1085-90. doi: 10.1038/ng.3379. Epub 2015 Aug 10.

41.

The EGF receptor ligand amphiregulin controls cell division via FoxM1.

Stoll SW, Stuart PE, Swindell WR, Tsoi LC, Li B, Gandarillas A, Lambert S, Johnston A, Nair RP, Elder JT.

Oncogene. 2016 Apr 21;35(16):2075-86. doi: 10.1038/onc.2015.269. Epub 2015 Aug 3.

42.

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools.

Ding J, Sidore C, Butler TJ, Wing MK, Qian Y, Meirelles O, Busonero F, Tsoi LC, Maschio A, Angius A, Kang HM, Nagaraja R, Cucca F, Abecasis GR, Schlessinger D.

PLoS Genet. 2015 Jul 14;11(7):e1005306. doi: 10.1371/journal.pgen.1005306. eCollection 2015 Jul. Erratum in: PLoS Genet. 2015 Sep;11(9):e1005549.

43.

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.

Tsoi LC, Spain SL, Ellinghaus E, Stuart PE, Capon F, Knight J, Tejasvi T, Kang HM, Allen MH, Lambert S, Stoll SW, Weidinger S, Gudjonsson JE, Koks S, Kingo K, Esko T, Das S, Metspalu A, Weichenthal M, Enerback C, Krueger GG, Voorhees JJ, Chandran V, Rosen CF, Rahman P, Gladman DD, Reis A, Nair RP, Franke A, Barker JNWN, Abecasis GR, Trembath RC, Elder JT.

Nat Commun. 2015 May 5;6:7001. doi: 10.1038/ncomms8001.

44.

Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin.

Tsoi LC, Iyer MK, Stuart PE, Swindell WR, Gudjonsson JE, Tejasvi T, Sarkar MK, Li B, Ding J, Voorhees JJ, Kang HM, Nair RP, Chinnaiyan AM, Abecasis GR, Elder JT.

Genome Biol. 2015 Jan 30;16:24. doi: 10.1186/s13059-014-0570-4.

45.

Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures.

Koch M, Baurecht H, Ried JS, Rodriguez E, Schlesinger S, Volks N, Gieger C, Rückert IM, Heinrich L, Willenborg C, Smith C, Peters A, Thorand B, Koenig W, Lamina C, Jansen H, Kronenberg F, Seissler J, Thiery J, Rathmann W, Schunkert H, Erdmann J, Barker J, Nair RP, Tsoi LC, Elder JT, Mrowietz U, Weichenthal M, Mucha S, Schreiber S, Franke A, Schmitt J, Lieb W, Weidinger S.

J Invest Dermatol. 2015 May;135(5):1283-1293. doi: 10.1038/jid.2015.8. Epub 2015 Jan 19.

46.

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.

Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, Ellinghaus D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger C, Hubner N, Illig T, Irvine AD, Kabesch M, Lee YA, Lieb W, Marenholz I, McLean WH, Morris DW, Mrowietz U, Nair R, Nöthen MM, Novak N, O'Regan GM; Psoriasis Association Genetics Extension, Schreiber S, Smith C, Strauch K, Stuart PE, Trembath R, Tsoi LC, Weichenthal M, Barker J, Elder JT, Weidinger S, Cordell HJ, Brown SJ.

Am J Hum Genet. 2015 Jan 8;96(1):104-20. doi: 10.1016/j.ajhg.2014.12.004. Erratum in: Am J Hum Genet. 2015 Dec 3;97(6):933.

47.

Graphical algorithm for integration of genetic and biological data: proof of principle using psoriasis as a model.

Tsoi LC, Elder JT, Abecasis GR.

Bioinformatics. 2015 Apr 15;31(8):1243-9. doi: 10.1093/bioinformatics/btu799. Epub 2014 Dec 4.

48.

Fine mapping of eight psoriasis susceptibility loci.

Das S, Stuart PE, Ding J, Tejasvi T, Li Y, Tsoi LC, Chandran V, Fischer J, Helms C, Duffin KC, Voorhees JJ, Bowcock AM, Krueger GG, Lathrop GM, Nair RP, Rahman P, Abecasis GR, Gladman D, Elder JT.

Eur J Hum Genet. 2015 Jun;23(6):844-53. doi: 10.1038/ejhg.2014.172. Epub 2014 Sep 3.

49.

Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.

Okada Y, Han B, Tsoi LC, Stuart PE, Ellinghaus E, Tejasvi T, Chandran V, Pellett F, Pollock R, Bowcock AM, Krueger GG, Weichenthal M, Voorhees JJ, Rahman P, Gregersen PK, Franke A, Nair RP, Abecasis GR, Gladman DD, Elder JT, de Bakker PI, Raychaudhuri S.

Am J Hum Genet. 2014 Aug 7;95(2):162-72. doi: 10.1016/j.ajhg.2014.07.002. Epub 2014 Jul 31.

50.

Finding pathway-modulating genes from a novel Ontology Fingerprint-derived gene network.

Qin T, Matmati N, Tsoi LC, Mohanty BK, Gao N, Tang J, Lawson AB, Hannun YA, Zheng WJ.

Nucleic Acids Res. 2014 Oct;42(18):e138. doi: 10.1093/nar/gku678. Epub 2014 Jul 24.

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