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Diurnal rhythms in gene expression in the prefrontal cortex in schizophrenia.

Seney ML, Cahill K, Enwright JF 3rd, Logan RW, Huo Z, Zong W, Tseng G, McClung CA.

Nat Commun. 2019 Aug 9;10(1):3355. doi: 10.1038/s41467-019-11335-1.


Immunological evaluation of a novel HLA-A2 restricted phosphopeptide of tumor associated Antigen, TRAP1, on cancer therapy.

Lin MH, Shen KY, Liu BS, Chen IH, Sher YP, Tseng GC, Liu SJ, Sung WC.

Vaccine X. 2019 Mar 11;1:100017. doi: 10.1016/j.jvacx.2019.100017. eCollection 2019 Apr 11.


Dynamic palmitoylation regulates trafficking of K channel interacting protein 2 (KChIP2) across multiple subcellular compartments in cardiac myocytes.

Murthy A, Workman SW, Jiang M, Hu J, Sifa I, Bernas T, Tang W, Deschenes I, Tseng GN.

J Mol Cell Cardiol. 2019 Oct;135:1-9. doi: 10.1016/j.yjmcc.2019.07.013. Epub 2019 Jul 27.


P-value evaluation, variability index and biomarker categorization for adaptively weighted Fisher's meta-analysis method in omics applications.

Huo Z, Tang S, Park Y, Tseng G.

Bioinformatics. 2019 Jul 29. pii: btz589. doi: 10.1093/bioinformatics/btz589. [Epub ahead of print]


S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane.

Jiang M, Hu J, White FKH, Williamson J, Klymchenko AS, Murthy A, Workman SW, Tseng GN.

J Biol Chem. 2019 Sep 6;294(36):13487-13501. doi: 10.1074/jbc.RA118.006772. Epub 2019 Jul 23.


A spontaneous protruded angle-supported anterior chamber intraocular lens: A case report.

Lin HL, Tseng GL.

Medicine (Baltimore). 2019 May;98(22):e15814. doi: 10.1097/MD.0000000000015814.


MethylSeqDesign: a framework for Methyl-Seq genome-wide power calculation and study design issues.

Liu P, Lin CW, Park Y, Tseng G.

Biostatistics. 2019 May 20. pii: kxz016. doi: 10.1093/biostatistics/kxz016. [Epub ahead of print]


Metabolites Associated with Vigor to Frailty Among Community-Dwelling Older Black Men.

Marron MM, Harris TB, Boudreau RM, Clish CB, Moore SC, Murphy RA, Murthy VL, Sanders JL, Shah RV, Tseng GC, Wendell SG, Zmuda JM, Newman AB.

Metabolites. 2019 Apr 30;9(5). pii: E83. doi: 10.3390/metabo9050083.


Host and Bacterial Markers that Differ in Children with Cystitis and Pyelonephritis.

Shaikh N, Martin JM, Hoberman A, Skae M, Milkovich L, Nowalk A, McElheny C, Hickey RW, Kearney D, Majd M, Shalaby-Rana E, Tseng G, Alcorn JF, Kolls J, Kurs-Lasky M, Huo Z, Horne W, Lockhart G, Pohl H, Shope TR.

J Pediatr. 2019 Jun;209:146-153.e1. doi: 10.1016/j.jpeds.2019.01.012. Epub 2019 Mar 21.


Meta-analytic framework for modeling genetic coexpression dynamics.

Kinzy TG, Starr TK, Tseng GC, Ho YY.

Stat Appl Genet Mol Biol. 2019 Feb 9;18(1). pii: /j/sagmb.2019.18.issue-1/sagmb-2017-0052/sagmb-2017-0052.xml. doi: 10.1515/sagmb-2017-0052.


Identification of recurrent fusion genes across multiple cancer types.

Yu YP, Liu P, Nelson J, Hamilton RL, Bhargava R, Michalopoulos G, Chen Q, Zhang J, Ma D, Pennathur A, Luketich J, Nalesnik M, Tseng G, Luo JH.

Sci Rep. 2019 Jan 31;9(1):1074. doi: 10.1038/s41598-019-38550-6.


DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions.

McKinney BC, Lin CW, Rahman T, Oh H, Lewis DA, Tseng G, Sibille E.

Transl Psychiatry. 2019 Jan 29;9(1):39. doi: 10.1038/s41398-019-0372-2.


Cisplatin-induced immune modulation in ovarian cancer mouse models with distinct inflammation profiles.

Grabosch S, Bulatovic M, Zeng F, Ma T, Zhang L, Ross M, Brozick J, Fang Y, Tseng G, Kim E, Gambotto A, Elishaev E, P Edwards R, Vlad AM.

Oncogene. 2019 Mar;38(13):2380-2393. doi: 10.1038/s41388-018-0581-9. Epub 2018 Dec 5.


MetaOmics: analysis pipeline and browser-based software suite for transcriptomic meta-analysis.

Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, Liu S, Wang L, Liu P, Rahman T, Chang LC, Kim S, Li J, Park Y, Song C, Oesterreich S, Sibille E, Tseng GC.

Bioinformatics. 2019 May 1;35(9):1597-1599. doi: 10.1093/bioinformatics/bty825.


The Evolution of Estrogen Receptor Signaling in the Progression of Endometriosis to Endometriosis-Associated Ovarian Cancer.

Andersen CL, Boisen MM, Sikora MJ, Ma T, Tseng G, Suryawanshi S, Vlad A, Elishaev E, Edwards RP, Oesterreich S.

Horm Cancer. 2018 Dec;9(6):399-407. doi: 10.1007/s12672-018-0350-9. Epub 2018 Oct 9.


Deep Brain Stimulation for Amelioration of Cognitive Impairment in Neurological Disorders: Neurogenesis and Circuit Reanimation.

Tsai ST, Harn HJ, Lin SZ, Tseng GF, Chen SY.

Cell Transplant. 2019 Jul;28(7):813-818. doi: 10.1177/0963689718804144. Epub 2018 Oct 9.


Diagnosis of T-cell-mediated kidney rejection in formalin-fixed, paraffin-embedded tissues using RNA-Seq-based machine learning algorithms.

Liu P, Tseng G, Wang Z, Huang Y, Randhawa P.

Hum Pathol. 2019 Feb;84:283-290. doi: 10.1016/j.humpath.2018.09.013. Epub 2018 Oct 6.


Gene Expression Signatures Can Aid Diagnosis of Sexually Transmitted Infection-Induced Endometritis in Women.

Zheng X, O'Connell CM, Zhong W, Poston TB, Wiesenfeld HC, Hillier SL, Trent M, Gaydos C, Tseng G, Taylor BD, Darville T.

Front Cell Infect Microbiol. 2018 Sep 20;8:307. doi: 10.3389/fcimb.2018.00307. eCollection 2018.


Activity Dependent Mammalian Target of Rapamycin Pathway and Brain Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Effects of Puerarin.

Huang CC, Tsai MH, Wu YC, Chen KT, Chuang HW, Chen Y, Tseng GW, Fu PI, Wei IH.

Am J Chin Med. 2018 Oct 4:1-16. doi: 10.1142/S0192415X18500787. [Epub ahead of print]


Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures.

Tasdemir N, Bossart EA, Li Z, Zhu L, Sikora MJ, Levine KM, Jacobsen BM, Tseng GC, Davidson NE, Oesterreich S.

Cancer Res. 2018 Nov 1;78(21):6209-6222. doi: 10.1158/0008-5472.CAN-18-1416. Epub 2018 Sep 18.


Bayesian integrative model for multi-omics data with missingness.

Fang Z, Ma T, Tang G, Zhu L, Yan Q, Wang T, Celedón JC, Chen W, Tseng GC.

Bioinformatics. 2018 Nov 15;34(22):3801-3808. doi: 10.1093/bioinformatics/bty775.


Chronic in vivo angiotensin II administration differentially modulates the slow delayed rectifier channels in atrial and ventricular myocytes.

Zankov DP, Salloum FN, Jiang M, Tseng GN.

Heart Rhythm. 2019 Jan;16(1):108-116. doi: 10.1016/j.hrthm.2018.07.036. Epub 2018 Aug 1.


Combined Systemic Disruption of MET and Epidermal Growth Factor Receptor Signaling Causes Liver Failure in Normal Mice.

Tsagianni A, Mars WM, Bhushan B, Bowen WC, Orr A, Stoops J, Paranjpe S, Tseng GC, Liu S, Michalopoulos GK.

Am J Pathol. 2018 Oct;188(10):2223-2235. doi: 10.1016/j.ajpath.2018.06.009. Epub 2018 Jul 20.


Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets.

Varešlija D, Priedigkeit N, Fagan A, Purcell S, Cosgrove N, O'Halloran PJ, Ward E, Cocchiglia S, Hartmaier R, Castro CA, Zhu L, Tseng GC, Lucas PC, Puhalla SL, Brufsky AM, Hamilton RL, Mathew A, Leone JP, Basudan A, Hudson L, Dwyer R, Das S, O'Connor DP, Buckley PG, Farrell M, Hill ADK, Oesterreich S, Lee AV, Young LS.

J Natl Cancer Inst. 2019 Apr 1;111(4):388-398. doi: 10.1093/jnci/djy110.


Improved identification of concordant and discordant gene expression signatures using an updated rank-rank hypergeometric overlap approach.

Cahill KM, Huo Z, Tseng GC, Logan RW, Seney ML.

Sci Rep. 2018 Jun 25;8(1):9588. doi: 10.1038/s41598-018-27903-2.


Pars plana insertion of glaucoma shunt in eyes with refractory neovascular glaucoma: Case report.

Yen CY, Tseng GL.

Medicine (Baltimore). 2018 Jun;97(23):e10977. doi: 10.1097/MD.0000000000010977.


Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.

Du T, Zhu L, Levine KM, Tasdemir N, Lee AV, Vignali DAA, Houten BV, Tseng GC, Oesterreich S.

Sci Rep. 2018 May 8;8(1):7205. doi: 10.1038/s41598-018-25357-0.


Opposite Molecular Signatures of Depression in Men and Women.

Seney ML, Huo Z, Cahill K, French L, Puralewski R, Zhang J, Logan RW, Tseng G, Lewis DA, Sibille E.

Biol Psychiatry. 2018 Jul 1;84(1):18-27. doi: 10.1016/j.biopsych.2018.01.017. Epub 2018 Feb 19.


Effectiveness and confounding factors of penetrating astigmatic keratotomy in clinical practice: Case report.

Yen CY, Tseng GL.

Medicine (Baltimore). 2018 Jan;97(4):e9709. doi: 10.1097/MD.0000000000009709.


Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies.

Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V.

Int J Antimicrob Agents. 2018 Mar;51(3):468-478. doi: 10.1016/j.ijantimicag.2017.12.032. Epub 2018 Jan 11. Review.


Meta-analytic principal component analysis in integrative omics application.

Kim S, Kang D, Huo Z, Park Y, Tseng GC.

Bioinformatics. 2018 Apr 15;34(8):1321-1328. doi: 10.1093/bioinformatics/btx765.


Transcriptome alterations of prefrontal cortical parvalbumin neurons in schizophrenia.

Enwright Iii JF, Huo Z, Arion D, Corradi JP, Tseng G, Lewis DA.

Mol Psychiatry. 2018 Jul;23(7):1606-1613. doi: 10.1038/mp.2017.216. Epub 2017 Nov 7.


Mini-Scleral Lenses for Correction of Refractive Errors After Radial Keratotomy.

Chu HS, Wang IJ, Tseng GA, Chen WL, Hou YC, Hu FR.

Eye Contact Lens. 2018 Nov;44 Suppl 2:S164-S168. doi: 10.1097/ICL.0000000000000437.


Integrative Sparse K-Means With Overlapping Group Lasso in Genomic Applications for Disease Subtype Discovery.

Huo Z, Tseng G.

Ann Appl Stat. 2017 Jun;11(2):1011-1039. doi: 10.1214/17-AOAS1033. Epub 2017 Jul 20.


Sustained Molecular Pathology Across Episodes and Remission in Major Depressive Disorder.

Scifo E, Pabba M, Kapadia F, Ma T, Lewis DA, Tseng GC, Sibille E.

Biol Psychiatry. 2018 Jan 1;83(1):81-89. doi: 10.1016/j.biopsych.2017.08.008. Epub 2017 Aug 18.


Surgical treatment of neovascular glaucoma with Ex-PRESS glaucoma shunt: Case report.

Yu TC, Tseng GL, Chen CC, Liou SW.

Medicine (Baltimore). 2017 Sep;96(35):e7845. doi: 10.1097/MD.0000000000007845.


Cortical compression rapidly trimmed transcallosal projections and altered axonal anterograde transport machinery.

Chen LJ, Wang YJ, Tseng GF.

Neuroscience. 2017 Oct 24;362:79-94. doi: 10.1016/j.neuroscience.2017.08.020. Epub 2017 Aug 19.


Biomarker detection and categorization in ribonucleic acid sequencing meta-analysis using Bayesian hierarchical models.

Ma T, Liang F, Tseng G.

J R Stat Soc Ser C Appl Stat. 2017 Aug;66(4):847-867. doi: 10.1111/rssc.12199. Epub 2016 Dec 16.


Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging.

Pabba M, Scifo E, Kapadia F, Nikolova YS, Ma T, Mechawar N, Tseng GC, Sibille E.

Neurobiol Aging. 2017 Oct;58:180-190. doi: 10.1016/j.neurobiolaging.2017.06.023. Epub 2017 Jul 5.


Comparing the effects of afatinib with gefitinib or Erlotinib in patients with advanced-stage lung adenocarcinoma harboring non-classical epidermal growth factor receptor mutations.

Shen YC, Tseng GC, Tu CY, Chen WC, Liao WC, Chen WC, Li CH, Chen HJ, Hsia TC.

Lung Cancer. 2017 Aug;110:56-62. doi: 10.1016/j.lungcan.2017.06.007. Epub 2017 Jun 13.


Age-Related Gene Expression in the Frontal Cortex Suggests Synaptic Function Changes in Specific Inhibitory Neuron Subtypes.

French L, Ma T, Oh H, Tseng GC, Sibille E.

Front Aging Neurosci. 2017 May 29;9:162. doi: 10.3389/fnagi.2017.00162. eCollection 2017.


Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the IKs Amplitude in Check Until When Larger IKs Is Needed.

Jiang M, Wang Y, Tseng GN.

Circ Arrhythm Electrophysiol. 2017 Jun;10(6). pii: e005084. doi: 10.1161/CIRCEP.117.005084.


A Joint Bayesian Model for Integrating Microarray and RNA Sequencing Transcriptomic Data.

Ma T, Liang F, Oesterreich S, Tseng GC.

J Comput Biol. 2017 Jul;24(7):647-662. doi: 10.1089/cmb.2017.0056. Epub 2017 May 25.


Multiplex profiling identifies distinct local and systemic alterations during intraperitoneal chemotherapy for ovarian cancer: An NRG Oncology/Gynecologic Oncology Group Study.

Grabosch S, Tseng G, Edwards RP, Lankes HA, Moore K, Odunsi K, Vlad A, Ma T, Strange M, Brozick J, Lugade A, Omilian A, Bshara W, Stuckey AR, Walker JL, Birrer M.

Gynecol Oncol. 2017 Jul;146(1):137-145. doi: 10.1016/j.ygyno.2017.04.008. Epub 2017 May 5.


Oncogenic activity of amplified miniature chromosome maintenance 8 in human malignancies.

He DM, Ren BG, Liu S, Tan LZ, Cieply K, Tseng G, Yu YP, Luo JH.

Oncogene. 2017 Jun 22;36(25):3629-3639. doi: 10.1038/onc.2017.123. Epub 2017 May 8.


Transcriptome Alterations in Prefrontal Pyramidal Cells Distinguish Schizophrenia From Bipolar and Major Depressive Disorders.

Arion D, Huo Z, Enwright JF, Corradi JP, Tseng G, Lewis DA.

Biol Psychiatry. 2017 Oct 15;82(8):594-600. doi: 10.1016/j.biopsych.2017.03.018. Epub 2017 Apr 4.


Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene.

Chen ZH, Yu YP, Zuo ZH, Nelson JB, Michalopoulos GK, Monga S, Liu S, Tseng G, Luo JH.

Nat Biotechnol. 2017 Jun;35(6):543-550. doi: 10.1038/nbt.3843. Epub 2017 May 1.

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