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Adjuvant Radiation Therapy Compared with Observation Alone for Postoperative Residual Nonfunctional Pituitary Adenomas.

Deng WC, Yan JL, Chuang CC, Wei KC, Chang CN, Wu CT, Chen HC, Wang CC, Tseng CK, Hsu PW.

World Neurosurg. 2019 May 17. pii: S1878-8750(19)31340-3. doi: 10.1016/j.wneu.2019.05.066. [Epub ahead of print]


A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.

Xia S, Yan L, Xu W, Agrawal AS, Algaissi A, Tseng CK, Wang Q, Du L, Tan W, Wilson IA, Jiang S, Yang B, Lu L.

Sci Adv. 2019 Apr 10;5(4):eaav4580. doi: 10.1126/sciadv.aav4580. eCollection 2019 Apr.


The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN.

Tseng CK, Wang HF, Schroeder MR, Baumann P.

Nat Commun. 2018 Dec 21;9(1):5430. doi: 10.1038/s41467-018-07822-6.


The dose-response effects of uric acid on the prevalence of metabolic syndrome and electrocardiographic left ventricular hypertrophy in healthy individuals.

Liu CW, Chen KH, Tseng CK, Chang WC, Wu YW, Hwang JJ.

Nutr Metab Cardiovasc Dis. 2019 Jan;29(1):30-38. doi: 10.1016/j.numecd.2018.10.001. Epub 2018 Oct 16.


Prostasin Impairs Epithelial Growth Factor Receptor Activation to Suppress Dengue Virus Propagation.

Lin CK, Tseng CK, Wu YH, Lin CY, Huang CH, Wang WH, Liaw CC, Chen YH, Lee JC.

J Infect Dis. 2019 Apr 16;219(9):1377-1388. doi: 10.1093/infdis/jiy677.


Discovery of 3-Amino-2-Hydroxypropoxyisoflavone Derivatives as Potential Anti-HCV Agents.

Lee JC, Lin CK, Tseng CK, Chen YL, Tzeng CC, Tseng CH.

Molecules. 2018 Nov 2;23(11). pii: E2863. doi: 10.3390/molecules23112863.


Dynamic protein-RNA interactions in mediating splicing catalysis.

Chung CS, Tseng CK, Lai YH, Wang HF, Newman AJ, Cheng SC.

Nucleic Acids Res. 2019 Jan 25;47(2):899-910. doi: 10.1093/nar/gky1089.


ICR suckling mouse model of Zika virus infection for disease modeling and drug validation.

Wu YH, Tseng CK, Lin CK, Wei CK, Lee JC, Young KC.

PLoS Negl Trop Dis. 2018 Oct 24;12(10):e0006848. doi: 10.1371/journal.pntd.0006848. eCollection 2018 Oct.


Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease.

Algaissi A, Agrawal AS, Han S, Peng BH, Luo C, Li F, Chan TS, Couch RB, Tseng CK.

J Infect Dis. 2019 Feb 15;219(5):829-835. doi: 10.1093/infdis/jiy574.


Demonstration of color display metasurfaces via immersion lithography on a 12-inch silicon wafer.

Hu T, Tseng CK, Fu YH, Xu Z, Dong Y, Wang S, Lai KH, Bliznetsov V, Zhu S, Lin Q, Gu Y.

Opt Express. 2018 Jul 23;26(15):19548-19554. doi: 10.1364/OE.26.019548.


Maintenance of multidomain neurocognitive functions in pediatric patients after proton beam therapy: A prospective case-series study.

Yang CC, Lin SY, Tseng CK.

Appl Neuropsychol Child. 2018 Jun 29:1-7. doi: 10.1080/21622965.2018.1471996. [Epub ahead of print]


Lobohedleolide suppresses hepatitis C virus replication via JNK/c-Jun-C/EBP-mediated down-regulation of cyclooxygenase-2 expression.

Lin CK, Tseng CK, Liaw CC, Huang CY, Wei CK, Sheu JH, Lee JC.

Sci Rep. 2018 Jun 6;8(1):8676. doi: 10.1038/s41598-018-26999-w.


Pretreatment subcutaneous adipose tissue predicts the outcomes of patients with head and neck cancer receiving definitive radiation and chemoradiation in Taiwan.

Pai PC, Chuang CC, Chuang WC, Tsang NM, Tseng CK, Chen KH, Yen TC, Lin CY, Chang KP, Lei KF.

Cancer Med. 2018 May;7(5):1630-1641. doi: 10.1002/cam4.1365. Epub 2018 Apr 2.


Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen.

Nyon MP, Du L, Tseng CK, Seid CA, Pollet J, Naceanceno KS, Agrawal A, Algaissi A, Peng BH, Tai W, Jiang S, Bottazzi ME, Strych U, Hotez PJ.

Vaccine. 2018 Mar 27;36(14):1853-1862. doi: 10.1016/j.vaccine.2018.02.065. Epub 2018 Feb 26.


Pretreatment clinical stage predicts locoregional recurrence in patients with esophageal cancer who achieved a complete clinical response to chemoradiotherapy.

Liw PX, Wen YW, Tsai CY, Chang HK, Tseng CK, Hung TM, Chao YK.

J Thorac Cardiovasc Surg. 2018 May;155(5):2233-2242.e2. doi: 10.1016/j.jtcvs.2017.12.082. Epub 2017 Dec 26.


Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1.

Chen WC, Tseng CK, Lin CK, Wang SN, Wang WH, Hsu SH, Wu YH, Hung LC, Chen YH, Lee JC.

Virulence. 2018 Jan 1;9(1):588-603. doi: 10.1080/21505594.2017.1421893.


Discovery of naphtho[1,2-d]oxazole derivatives as potential anti-HCV agents through inducing heme oxygenase-1 expression.

Tseng CH, Lin CK, Chen YL, Tseng CK, Lee JY, Lee JC.

Eur J Med Chem. 2018 Jan 1;143:970-982. doi: 10.1016/j.ejmech.2017.12.006. Epub 2017 Dec 5.


An analysis of factors affecting the accuracy of endoscopic biopsy after neoadjuvant chemoradiotherapy in patients with esophageal squamous cell carcinoma.

Chao YK, Wen YW, Chang HK, Tseng CK, Liu YH.

Eur J Surg Oncol. 2017 Dec;43(12):2366-2373. doi: 10.1016/j.ejso.2017.09.022. Epub 2017 Oct 16.


Discovery of novel diarylpyrazolylquinoline derivatives as potent anti-dengue virus agents.

Lee JC, Tseng CK, Lin CK, Tseng CH.

Eur J Med Chem. 2017 Dec 1;141:282-292. doi: 10.1016/j.ejmech.2017.10.001. Epub 2017 Oct 3.


Anatomical distribution of residual cancer in patients with oesophageal squamous cell carcinoma who achieved clinically complete response after neoadjuvant chemoradiotherapy.

Chao YK, Chuang WY, Yeh CJ, Chang HK, Tseng CK.

Eur J Cardiothorac Surg. 2018 Jan 1;53(1):201-208. doi: 10.1093/ejcts/ezx261.


Celastrol inhibits hepatitis C virus replication by upregulating heme oxygenase-1 via the JNK MAPK/Nrf2 pathway in human hepatoma cells.

Tseng CK, Hsu SP, Lin CK, Wu YH, Lee JC, Young KC.

Antiviral Res. 2017 Oct;146:191-200. doi: 10.1016/j.antiviral.2017.09.010. Epub 2017 Sep 19.


Dose-escalated radiation therapy is associated with better overall survival in patients with bone metastases from solid tumors: a propensity score-matched study.

Chou YC, Lin CY, Pai PC, Tseng CK, Hsieh CE, Chang KP, Hsu CL, Liao CT, Wang CC, Chin SC, Yen TC, Ho TY, Hong JH, Lei KF, Chang JT, Tsang NM.

Cancer Med. 2017 Sep;6(9):2087-2097. doi: 10.1002/cam4.1150. Epub 2017 Aug 15.


Perineural invasion through the sheath in posttherapy esophagectomy specimens predicts poor survival in patients with esophageal squamous cell carcinoma.

Tsai CY, Yeh CJ, Chao YK, Chang HK, Tseng CK, Liu YH.

Eur J Surg Oncol. 2017 Oct;43(10):1970-1976. doi: 10.1016/j.ejso.2017.07.014. Epub 2017 Aug 3.


Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities.

Pelliccia S, Wu YH, Coluccia A, La Regina G, Tseng CK, Famiglini V, Masci D, Hiscott J, Lee JC, Silvestri R.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):1091-1101. doi: 10.1080/14756366.2017.1355791.


Predictive value of nodal maximum standardized uptake value of pretreatment [18F]fluorodeoxyglucose positron emission tomography imaging in patients with esophageal cancer.

Yap WK, Chang YC, Tseng CK, Hsieh CH, Chao YK, Su PJ, Hou MM, Yang CK, Pai PC, Lin CR, Hsieh CE, Wu YY, Hung TM.

Dis Esophagus. 2017 Aug 1;30(8):1-10. doi: 10.1093/dote/dox021.


GALNT14 genotype as a response predictor for concurrent chemoradiotherapy in advanced esophageal squamous cell carcinoma.

Tsou YK, Liang KH, Lin WR, Chang HK, Tseng CK, Yeh CT.

Oncotarget. 2017 Apr 25;8(17):29151-29160. doi: 10.18632/oncotarget.16253.


Schisandrin A inhibits dengue viral replication via upregulating antiviral interferon responses through STAT signaling pathway.

Yu JS, Wu YH, Tseng CK, Lin CK, Hsu YC, Chen YH, Lee JC.

Sci Rep. 2017 Mar 24;7:45171. doi: 10.1038/srep45171.


Cyclooxygenase-2 facilitates dengue virus replication and serves as a potential target for developing antiviral agents.

Lin CK, Tseng CK, Wu YH, Liaw CC, Lin CY, Huang CH, Chen YH, Lee JC.

Sci Rep. 2017 Mar 20;7:44701. doi: 10.1038/srep44701.


Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection.

Wang Y, Tai W, Yang J, Zhao G, Sun S, Tseng CK, Jiang S, Zhou Y, Du L, Gao J.

Hum Vaccin Immunother. 2017 Jul 3;13(7):1615-1624. doi: 10.1080/21645515.2017.1296994. Epub 2017 Mar 9.


Grape Seed Extract Attenuates Hepatitis C Virus Replication and Virus-Induced Inflammation.

Chen WC, Tseng CK, Chen BH, Lin CK, Lee JC.

Front Pharmacol. 2016 Dec 21;7:490. doi: 10.3389/fphar.2016.00490. eCollection 2016.


A central role of Cwc25 in spliceosome dynamics during the catalytic phase of pre-mRNA splicing.

Tseng CK, Chung CS, Chen HC, Cheng SC.

RNA. 2017 Apr;23(4):546-556. doi: 10.1261/rna.059204.116. Epub 2017 Jan 5.


Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines.

Du L, Tai W, Yang Y, Zhao G, Zhu Q, Sun S, Liu C, Tao X, Tseng CK, Perlman S, Jiang S, Zhou Y, Li F.

Nat Commun. 2016 Nov 22;7:13473. doi: 10.1038/ncomms13473.


Celastrol inhibits dengue virus replication via up-regulating type I interferon and downstream interferon-stimulated responses.

Yu JS, Tseng CK, Lin CK, Hsu YC, Wu YH, Hsieh CL, Lee JC.

Antiviral Res. 2017 Jan;137:49-57. doi: 10.1016/j.antiviral.2016.11.010. Epub 2016 Nov 12.


Postoperative Adjuvant Therapy Improves Survival in Pathologic Nonresponders After Neoadjuvant Chemoradiation for Esophageal Squamous Cell Carcinoma: A Propensity-Matched Analysis.

Hsu HY, Chao YK, Hsieh CH, Wen YW, Chang HK, Tseng CK, Liu YH.

Ann Thorac Surg. 2016 Nov;102(5):1687-1693. doi: 10.1016/j.athoracsur.2016.05.026. Epub 2016 Jul 22.


Long Term Surgical Outcome and Prognostic Factors of Atypical and Malignant Meningiomas.

Wang YC, Chuang CC, Wei KC, Chang CN, Lee ST, Wu CT, Hsu YH, Lin TK, Hsu PW, Huang YC, Tseng CK, Wang CC, Chen YL, Chen PY.

Sci Rep. 2016 Oct 20;6:35743. doi: 10.1038/srep35743.


A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection.

Tai W, Zhao G, Sun S, Guo Y, Wang Y, Tao X, Tseng CK, Li F, Jiang S, Du L, Zhou Y.

Virology. 2016 Dec;499:375-382. doi: 10.1016/j.virol.2016.10.005. Epub 2016 Oct 15.


Unexpected Microscopically Positive Proximal Resection Margins in Esophageal Squamous Cell Carcinoma After Chemoradiotherapy: Predictors and Prognostic Significance.

Chiu CH, Chao YK, Wen YW, Chang HK, Tseng CK, Liu YH.

World J Surg. 2017 Jan;41(1):191-199. doi: 10.1007/s00268-016-3734-4.


Characterization of residual tumours at the primary site in patients with a near pathological complete response after neoadjuvant chemoradiotherapy for oesophageal cancer.

Chao YK, Chang Y, Yeh CJ, Chang HK, Tseng CK, Chuang WY.

Br J Surg. 2016 Dec;103(13):1874-1879. doi: 10.1002/bjs.10293. Epub 2016 Sep 13.


Human heme oxygenase 1 is a potential host cell factor against dengue virus replication.

Tseng CK, Lin CK, Wu YH, Chen YH, Chen WC, Young KC, Lee JC.

Sci Rep. 2016 Aug 24;6:32176. doi: 10.1038/srep32176.


Circulating Tumour Cells as an Independent Prognostic Factor in Patients with Advanced Oesophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy.

Su PJ, Wu MH, Wang HM, Lee CL, Huang WK, Wu CE, Chang HK, Chao YK, Tseng CK, Chiu TK, Lin NM, Ye SR, Lee JY, Hsieh CH.

Sci Rep. 2016 Aug 17;6:31423. doi: 10.1038/srep31423.


Prognosis of patients with esophageal squamous cell carcinoma who achieve major histopathological response after neoadjuvant chemoradiotherapy.

Chao YK, Chuang WY, Chang HK, Tseng CK, Yeh CJ, Liu YH.

Eur J Surg Oncol. 2017 Jan;43(1):234-239. doi: 10.1016/j.ejso.2016.05.036. Epub 2016 Jun 17.


Oligodendrogliomas in Children: Clinical Experiences With 20 Patients.

Wu CT, Tsay PK, Jaing TH, Chen SH, Tseng CK, Jung SM.

J Pediatr Hematol Oncol. 2016 Oct;38(7):555-8. doi: 10.1097/MPH.0000000000000610.


Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway.

Yu JS, Chen WC, Tseng CK, Lin CK, Hsu YC, Chen YH, Lee JC.

PLoS One. 2016 Mar 29;11(3):e0152236. doi: 10.1371/journal.pone.0152236. eCollection 2016.


Overweight and obesity predict better overall survival rates in cancer patients with distant metastases.

Tsang NM, Pai PC, Chuang CC, Chuang WC, Tseng CK, Chang KP, Yen TC, Lin JD, Chang JT.

Cancer Med. 2016 Apr;5(4):665-75. doi: 10.1002/cam4.634. Epub 2016 Jan 26.


Phosphorylated mTOR expression correlates with podoplanin expression and high tumor grade in esophageal squamous cell carcinoma.

Chuang WY, Chang YS, Chao YK, Yeh CJ, Ueng SH, Chang CY, Liu YH, Tseng CK, Chang HK, Wan YL, Hsueh C.

Int J Clin Exp Pathol. 2015 Oct 1;8(10):12757-65. eCollection 2015.


Hippocampal dosimetry correlates with the change in neurocognitive function after hippocampal sparing during whole brain radiotherapy: a prospective study.

Tsai PF, Yang CC, Chuang CC, Huang TY, Wu YM, Pai PC, Tseng CK, Wu TH, Shen YL, Lin SY.

Radiat Oncol. 2015 Dec 10;10:253. doi: 10.1186/s13014-015-0562-x.


Human Telomerase RNA Processing and Quality Control.

Tseng CK, Wang HF, Burns AM, Schroeder MR, Gaspari M, Baumann P.

Cell Rep. 2015 Dec 15;13(10):2232-43. doi: 10.1016/j.celrep.2015.10.075. Epub 2015 Nov 25.

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