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Items: 46


Sex differences underlying pancreatic islet biology and its dysfunction.

Gannon M, Kulkarni RN, Tse HM, Mauvais-Jarvis F.

Mol Metab. 2018 May 30. pii: S2212-8778(18)30520-9. doi: 10.1016/j.molmet.2018.05.017. [Epub ahead of print] Review.


Redox-Dependent Inflammation in Islet Transplantation Rejection.

Barra JM, Tse HM.

Front Endocrinol (Lausanne). 2018 Apr 23;9:175. doi: 10.3389/fendo.2018.00175. eCollection 2018. Review.


Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance.

Pepin ME, Padgett LE, McDowell RE, Burg AR, Brahma MK, Holleman C, Kim T, Crossman D, Kutsch O, Tse HM, Wende AR, Habegger KM.

Mol Metab. 2018 Jun;12:48-61. doi: 10.1016/j.molmet.2018.04.006. Epub 2018 Apr 20.


The proinflammatory effects of macrophage-derived NADPH oxidase function in autoimmune diabetes.

Feduska JM, Tse HM.

Free Radic Biol Med. 2018 Apr 30. pii: S0891-5849(18)30802-5. doi: 10.1016/j.freeradbiomed.2018.04.581. [Epub ahead of print] Review.


Superoxide Production by NADPH Oxidase Intensifies Macrophage Antiviral Responses during Diabetogenic Coxsackievirus Infection.

Burg AR, Das S, Padgett LE, Koenig ZE, Tse HM.

J Immunol. 2018 Jan 1;200(1):61-70. doi: 10.4049/jimmunol.1700478. Epub 2017 Nov 20.


Redox-Sensitive Innate Immune Pathways During Macrophage Activation in Type 1 Diabetes.

Burg AR, Tse HM.

Antioxid Redox Signal. 2017 Nov 27. doi: 10.1089/ars.2017.7243. [Epub ahead of print]


Islet encapsulation with polyphenol coatings decreases pro-inflammatory chemokine synthesis and T cell trafficking.

Pham-Hua D, Padgett LE, Xue B, Anderson B, Zeiger M, Barra JM, Bethea M, Hunter CS, Kozlovskaya V, Kharlampieva E, Tse HM.

Biomaterials. 2017 Jun;128:19-32. doi: 10.1016/j.biomaterials.2017.03.002. Epub 2017 Mar 6.


Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2β (Group VIA Phospholipase A2).

Ashley JW, Hancock WD, Nelson AJ, Bone RN, Tse HM, Wohltmann M, Turk J, Ramanadham S.

J Biol Chem. 2016 Oct 28;291(44):23268-23281. Epub 2016 Sep 20.


NADPH Oxidase-Derived Superoxide Provides a Third Signal for CD4 T Cell Effector Responses.

Padgett LE, Tse HM.

J Immunol. 2016 Sep 1;197(5):1733-42. doi: 10.4049/jimmunol.1502581. Epub 2016 Jul 29.


Minireview: Directed Differentiation and Encapsulation of Islet β-Cells-Recent Advances and Future Considerations.

Tse HM, Kozlovskaya V, Kharlampieva E, Hunter CS.

Mol Endocrinol. 2015 Oct;29(10):1388-99. doi: 10.1210/me.2015-1085. Epub 2015 Sep 4. Review.


Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T-Cell Effector Responses in Type 1 Diabetes.

Padgett LE, Anderson B, Liu C, Ganini D, Mason RP, Piganelli JD, Mathews CE, Tse HM.

Diabetes. 2015 Dec;64(12):4171-83. doi: 10.2337/db15-0546. Epub 2015 Aug 12.


Hydrogen-bonded multilayers of tannic acid as mediators of T-cell immunity.

Kozlovskaya V, Xue B, Lei W, Padgett LE, Tse HM, Kharlampieva E.

Adv Healthc Mater. 2015 Apr 2;4(5):686-94. doi: 10.1002/adhm.201400657. Epub 2014 Dec 9.


LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity.

Liu HF, Lu S, Ho PW, Tse HM, Pang SY, Kung MH, Ho JW, Ramsden DB, Zhou ZJ, Ho SL.

Ann Clin Transl Neurol. 2014 Mar;1(3):199-208. doi: 10.1002/acn3.45. Epub 2014 Mar 4.


Loss of NADPH oxidase-derived superoxide skews macrophage phenotypes to delay type 1 diabetes.

Padgett LE, Burg AR, Lei W, Tse HM.

Diabetes. 2015 Mar;64(3):937-46. doi: 10.2337/db14-0929. Epub 2014 Oct 6.


Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.

Bone RN, Gai Y, Magrioti V, Kokotou MG, Ali T, Lei X, Tse HM, Kokotos G, Ramanadham S.

Diabetes. 2015 Feb;64(2):541-54. doi: 10.2337/db14-0097. Epub 2014 Sep 11.


Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development.

Lei X, Bone RN, Ali T, Zhang S, Bohrer A, Tse HM, Bidasee KR, Ramanadham S.

Endocrinology. 2014 Sep;155(9):3352-64. doi: 10.1210/en.2013-2134. Epub 2014 Jul 8.


Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer.

Leung YK, Chan QK, Ng CF, Ma FM, Tse HM, To KF, Maranchie J, Ho SM, Lau KM.

PLoS One. 2014 May 16;9(5):e98037. doi: 10.1371/journal.pone.0098037. eCollection 2014.


Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways.

Sawant A, Schafer CC, Jin TH, Zmijewski J, Tse HM, Roth J, Sun Z, Siegal GP, Thannickal VJ, Grant SC, Ponnazhagan S, Deshane JS.

Cancer Res. 2013 Nov 15;73(22):6609-20. doi: 10.1158/0008-5472.CAN-13-0987. Epub 2013 Oct 1.


Diabetes-related impairment in bone strength is established early in the life course.

Casazza K, Hanks LJ, Clines GA, Tse HM, Eberhardt AW.

World J Diabetes. 2013 Aug 15;4(4):145-50. doi: 10.4239/wjd.v4.i4.145.


Ultrathin polymeric coatings based on hydrogen-bonded polyphenol for protection of pancreatic islet cells.

Kozlovskaya V, Zavgorodnya O, Chen Y, Ellis K, Tse HM, Cui W, Thompson JA, Kharlampieva E.

Adv Funct Mater. 2012 Aug 21;22(16):3389-3398. Epub 2012 Apr 30.


Effects of metalloporphyrins on reducing inflammation and autoimmunity.

Delmastro-Greenwood MM, Tse HM, Piganelli JD.

Antioxid Redox Signal. 2014 May 20;20(15):2465-77. doi: 10.1089/ars.2013.5257. Epub 2013 Apr 19. Review.


The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis.

Padgett LE, Broniowska KA, Hansen PA, Corbett JA, Tse HM.

Ann N Y Acad Sci. 2013 Apr;1281:16-35. doi: 10.1111/j.1749-6632.2012.06826.x. Epub 2013 Jan 16. Review.


Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells.

Ho PW, Ho JW, Tse HM, So DH, Yiu DC, Liu HF, Chan KH, Kung MH, Ramsden DB, Ho SL.

PLoS One. 2012;7(2):e32810. doi: 10.1371/journal.pone.0032810. Epub 2012 Feb 29.


Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice.

Seleme MC, Lei W, Burg AR, Goh KY, Metz A, Steele C, Tse HM.

Free Radic Biol Med. 2012 May 1;52(9):2047-56. doi: 10.1016/j.freeradbiomed.2012.01.027. Epub 2012 Feb 4.


A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice.

Lin MS, Tse HM, Delmastro MM, Bertera S, Wong CT, Lakomy R, He J, Sklavos MM, Coudriet GM, Pietropaolo M, Trucco MM, Piganelli JD.

Immunol Res. 2011 Aug;50(2-3):213-20. doi: 10.1007/s12026-011-8215-0.


Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.

Thayer TC, Delano M, Liu C, Chen J, Padgett LE, Tse HM, Annamali M, Piganelli JD, Moldawer LL, Mathews CE.

Diabetes. 2011 Aug;60(8):2144-51. doi: 10.2337/db10-1222. Epub 2011 Jun 29.


Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage.

Sheng H, Spasojevic I, Tse HM, Jung JY, Hong J, Zhang Z, Piganelli JD, Batinic-Haberle I, Warner DS.

J Pharmacol Exp Ther. 2011 Sep;338(3):906-16. doi: 10.1124/jpet.110.176701. Epub 2011 Jun 7.


Aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome (HIDS).

Hager EJ, Piganelli JD, Tse HM, Gibson KM.

J Inherit Metab Dis. 2012 Jan;35(1):159-68. doi: 10.1007/s10545-011-9349-x. Epub 2011 May 24.


NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

Tse HM, Thayer TC, Steele C, Cuda CM, Morel L, Piganelli JD, Mathews CE.

J Immunol. 2010 Nov 1;185(9):5247-58. doi: 10.4049/jimmunol.1001472. Epub 2010 Sep 29.


Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.

Batinic-Haberle I, Spasojevic I, Tse HM, Tovmasyan A, Rajic Z, St Clair DK, Vujaskovic Z, Dewhirst MW, Piganelli JD.

Amino Acids. 2012 Jan;42(1):95-113. doi: 10.1007/s00726-010-0603-6. Epub 2010 May 16. Review. Erratum in: Amino Acids. 2012 Jan;42(1):115-6.


Redox modulation protects islets from transplant-related injury.

Sklavos MM, Bertera S, Tse HM, Bottino R, He J, Beilke JN, Coulombe MG, Gill RG, Crapo JD, Trucco M, Piganelli JD.

Diabetes. 2010 Jul;59(7):1731-8. doi: 10.2337/db09-0588. Epub 2010 Apr 22.


Effects of SP6 acupressure on pain and menstrual distress in young women with dysmenorrhea.

Wong CL, Lai KY, Tse HM.

Complement Ther Clin Pract. 2010 May;16(2):64-9. doi: 10.1016/j.ctcp.2009.10.002. Epub 2009 Nov 14.


FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages.

Su D, Coudriet GM, Hyun Kim D, Lu Y, Perdomo G, Qu S, Slusher S, Tse HM, Piganelli J, Giannoukakis N, Zhang J, Dong HH.

Diabetes. 2009 Nov;58(11):2624-33. doi: 10.2337/db09-0232. Epub 2009 Aug 3.


Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.

Sheng H, Yang W, Fukuda S, Tse HM, Paschen W, Johnson K, Batinic-Haberle I, Crapo JD, Pearlstein RD, Piganelli J, Warner DS.

Free Radic Biol Med. 2009 Oct 1;47(7):917-23. doi: 10.1016/j.freeradbiomed.2009.05.039. Epub 2009 Jul 22.


Redox modulation inhibits CD8 T cell effector function.

Sklavos MM, Tse HM, Piganelli JD.

Free Radic Biol Med. 2008 Nov 15;45(10):1477-86. doi: 10.1016/j.freeradbiomed.2008.08.023. Epub 2008 Sep 9.


Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kappaB activation in vascular smooth muscle cells.

Cifarelli V, Luppi P, Tse HM, He J, Piganelli J, Trucco M.

Atherosclerosis. 2008 Dec;201(2):248-57. doi: 10.1016/j.atherosclerosis.2007.12.060. Epub 2008 Feb 21.


Deletion of a single mevalonate kinase (Mvk) allele yields a murine model of hyper-IgD syndrome.

Hager EJ, Tse HM, Piganelli JD, Gupta M, Baetscher M, Tse TE, Pappu AS, Steiner RD, Hoffmann GF, Gibson KM.

J Inherit Metab Dis. 2007 Nov;30(6):888-95. Epub 2007 Nov 19.


Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness.

Tse HM, Milton MJ, Schreiner S, Profozich JL, Trucco M, Piganelli JD.

J Immunol. 2007 Jan 15;178(2):908-17.


Modulatory role of DR4- to DQ8-restricted CD4 T-cell responses and type 1 diabetes susceptibility.

Ge X, Piganelli JD, Tse HM, Bertera S, Mathews CE, Trucco M, Wen L, Rudert WA.

Diabetes. 2006 Dec;55(12):3455-62.


A survey of attitudes to traditional chinese medicine among Chinese medical students.

Hon KL, Leung TF, Tse HM, Lam LN, Tam KC, Chu KM, Wong Y, Fok TF.

Am J Chin Med. 2005;33(2):269-79.


A survey of attitudes to Traditional Chinese Medicine in Hong Kong pharmacy students.

Hon EK, Lee K, Tse HM, Lam LN, Tam KC, Chu KM, Lee V, Lau C, Leung TF.

Complement Ther Med. 2004 Mar;12(1):51-6.


Caspase-1 is not required for type 1 diabetes in the NOD mouse.

Schott WH, Haskell BD, Tse HM, Milton MJ, Piganelli JD, Choisy-Rossi CM, Reifsnyder PC, Chervonsky AV, Leiter EH.

Diabetes. 2004 Jan;53(1):99-104.

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