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Low-dose nivolumab induced durable complete response in relapsed primary central nervous system diffuse large B cell lymphoma.

Chan TSY, Khong PL, Au-Yeung R, Kwong YL, Tse E.

Ann Hematol. 2019 Sep;98(9):2227-2230. doi: 10.1007/s00277-019-03758-z. Epub 2019 Jul 26. No abstract available.


Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.

Rizo AN, Lin J, Gates SN, Tse E, Bart SM, Castellano LM, DiMaio F, Shorter J, Southworth DR.

Nat Commun. 2019 Jun 3;10(1):2393. doi: 10.1038/s41467-019-10150-y.


Stereotactic body radiation therapy for early hepatocellular carcinoma: a retrospective analysis of the South Australian experience.

Wigg AJ, Narayana SK, Le H, Iankov I, Chinnaratha MA, Tse E, Chen JW, Gowda R.

ANZ J Surg. 2019 Apr 15. doi: 10.1111/ans.15130. [Epub ahead of print]


Beneficial response to mycophenolate mofetil by patients with autoimmune hepatitis who have failed standard therapy, is predicted by older age and lower immunoglobulin G and INR levels.

Nicoll AJ, Roberts SK, Lim R, Mitchell J, Weltman M, George J, Wigg A, Stuart K, Gow P, MacQuillan G, Tse E, Levy M, Sood S, Zekry A, Cheng W, Mitchell J, Skoien R, Sievert W, Strasser SI, McCaughan GW; ALA Clinical Research Network, Gastroenterological Society of Australia.

Aliment Pharmacol Ther. 2019 May;49(10):1314-1322. doi: 10.1111/apt.15248. Epub 2019 Apr 11.


The past, present and future of anti-malarial medicines.

Tse EG, Korsik M, Todd MH.

Malar J. 2019 Mar 22;18(1):93. doi: 10.1186/s12936-019-2724-z. Review.


Direct medical costs in the preceding, event and subsequent years of a first severe hypoglycaemia episode requiring hospitalization: A population-based cohort study.

Wong CKH, Tong T, Cheng GHL, Tang EHM, Thokala P, Tse ETY, Lam CLK.

Diabetes Obes Metab. 2019 Jun;21(6):1330-1339. doi: 10.1111/dom.13657. Epub 2019 Mar 19.


Chaperone activation and client binding of a 2-cysteine peroxiredoxin.

Teixeira F, Tse E, Castro H, Makepeace KAT, Meinen BA, Borchers CH, Poole LB, Bardwell JC, Tomás AM, Southworth DR, Jakob U.

Nat Commun. 2019 Feb 8;10(1):659. doi: 10.1038/s41467-019-08565-8.


Effective Distance for DNA-Mediated Charge Transport between Repair Proteins.

Tse ECM, Zwang TJ, Bedoya S, Barton JK.

ACS Cent Sci. 2019 Jan 23;5(1):65-72. doi: 10.1021/acscentsci.8b00566. Epub 2019 Jan 11.


Rapid versus gradual lung function decline in bronchiolitis obliterans syndrome after haematopoietic stem cell transplantation is associated with survival outcome.

Kwok WC, Liang BM, Lui MMS, Tam TCC, Sim JPY, Tse EWC, Leung AYH, Kwong YL, Lie AKW, Ip MSM, Lam DCL.

Respirology. 2019 May;24(5):459-466. doi: 10.1111/resp.13472. Epub 2019 Jan 20.


PIN1 in Cell Cycle Control and Cancer.

Cheng CW, Tse E.

Front Pharmacol. 2018 Nov 26;9:1367. doi: 10.3389/fphar.2018.01367. eCollection 2018. Review.


Effect of Obstructive Sleep Apnea on Cardiovascular Function in Obese Youth.

Hui W, Slorach C, Guerra V, Parekh RS, Hamilton J, Messiha S, Tse E, Mertens L, Narang I.

Am J Cardiol. 2019 Jan 15;123(2):341-347. doi: 10.1016/j.amjcard.2018.09.038. Epub 2018 Oct 18.


Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau.

Freilich R, Betegon M, Tse E, Mok SA, Julien O, Agard DA, Southworth DR, Takeuchi K, Gestwicki JE.

Nat Commun. 2018 Nov 1;9(1):4563. doi: 10.1038/s41467-018-07012-4.


Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities.

Munawar S, Windley MJ, Tse EG, Todd MH, Hill AP, Vandenberg JI, Jabeen I.

Front Pharmacol. 2018 Sep 19;9:1035. doi: 10.3389/fphar.2018.01035. eCollection 2018.


Coordinated care for patients with cirrhosis: fewer liver-related emergency admissions and improved survival.

Ramachandran J, Hossain M, Hrycek C, Tse E, Muller KR, Woodman RJ, Kaambwa B, Wigg AJ.

Med J Aust. 2018 Sep 1;209(7):301-305.


Controlling Proton and Electron Transfer Rates to Enhance the Activity of an Oxygen Reduction Electrocatalyst.

Gautam RP, Lee YT, Herman GL, Moreno CM, Tse ECM, Barile CJ.

Angew Chem Int Ed Engl. 2018 Oct 8;57(41):13480-13483. doi: 10.1002/anie.201806795. Epub 2018 Sep 17.


Polyphosphate Stabilizes Protein Unfolding Intermediates as Soluble Amyloid-like Oligomers.

Yoo NG, Dogra S, Meinen BA, Tse E, Haefliger J, Southworth DR, Gray MJ, Dahl JU, Jakob U.

J Mol Biol. 2018 Oct 19;430(21):4195-4208. doi: 10.1016/j.jmb.2018.08.016. Epub 2018 Aug 18.


Cell Cycle-Dependent Uptake and Cytotoxicity of Arsenic-Based Drugs in Single Leukemia Cells.

Zhou Y, Wang H, Tse E, Li H, Sun H.

Anal Chem. 2018 Sep 4;90(17):10465-10471. doi: 10.1021/acs.analchem.8b02444. Epub 2018 Aug 21.


Real-world outcomes of unrestricted direct-acting antiviral treatment for hepatitis C in Australia: The South Australian statewide experience.

Haridy J, Wigg A, Muller K, Ramachandran J, Tilley E, Waddell V, Gordon D, Shaw D, Huynh D, Stewart J, Nelson R, Warner M, Boyd M, Chinnaratha MA, Harding D, Ralton L, Colman A, Liew D, Iyngkaran G, Tse E; Adelaide Liver Group.

J Viral Hepat. 2018 Nov;25(11):1287-1297. doi: 10.1111/jvh.12943. Epub 2018 Jul 10.


Sensing DNA through DNA Charge Transport.

Zwang TJ, Tse ECM, Barton JK.

ACS Chem Biol. 2018 Jul 20;13(7):1799-1809. doi: 10.1021/acschembio.8b00347. Epub 2018 Jun 1. Review.


A Compass at Weak Magnetic Fields Using Thymine Dimer Repair.

Zwang TJ, Tse ECM, Zhong D, Barton JK.

ACS Cent Sci. 2018 Mar 28;4(3):405-412. doi: 10.1021/acscentsci.8b00008. Epub 2018 Mar 7.


Role of the saturated fatty acid palmitate in the interconnected hypothalamic control of energy homeostasis and biological rhythms.

Tse EK, Salehi A, Clemenzi MN, Belsham DD.

Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E133-E140. doi: 10.1152/ajpendo.00433.2017. Epub 2018 Apr 6. Review.


Orthognathic Relevant Scales of FACE-Q: Translation and Validation for Hong Kong Chinese Patients.

Tan SK, Leung WK, Tang ATH, Tse ECM, Zwahlen RA.

Plast Reconstr Surg Glob Open. 2017 Dec 28;5(12):e1608. doi: 10.1097/GOX.0000000000001608. eCollection 2017 Dec.


Long-term outcome of relapsed acute promyelocytic leukemia treated with oral arsenic trioxide-based reinduction and maintenance regimens: A 15-year prospective study.

Gill H, Yim R, Lee HKK, Mak V, Lin SY, Kho B, Yip SF, Lau JSM, Li W, Ip HW, Hwang YY, Chan TSY, Tse E, Au WY, Kumana CR, Kwong YL.

Cancer. 2018 Jun 1;124(11):2316-2326. doi: 10.1002/cncr.31327. Epub 2018 Mar 26.


Immunologic Milieu of Mature T-Cell and NK-Cell Lymphomas-Implications for Therapy.

Tse E, Kwong YL.

Curr Hematol Malig Rep. 2018 Feb;13(1):37-43. doi: 10.1007/s11899-018-0437-y. Review.


X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition.

Cesa LC, Shao H, Srinivasan SR, Tse E, Jain C, Zuiderweg ERP, Southworth DR, Mapp AK, Gestwicki JE.

J Biol Chem. 2018 Feb 16;293(7):2370-2380. doi: 10.1074/jbc.RA117.000634. Epub 2017 Dec 18.


Palmitate induces neuroinflammation, ER stress, and Pomc mRNA expression in hypothalamic mHypoA-POMC/GFP neurons through novel mechanisms that are prevented by oleate.

Tse EK, Belsham DD.

Mol Cell Endocrinol. 2018 Sep 5;472:40-49. doi: 10.1016/j.mce.2017.11.017. Epub 2017 Nov 24.


The peptidyl-prolyl isomerase PIN1 relieves cyclin-dependent kinase 2 (CDK2) inhibition by the CDK inhibitor p27.

Cheng CW, Leong KW, Ng YM, Kwong YL, Tse E.

J Biol Chem. 2017 Dec 29;292(52):21431-21441. doi: 10.1074/jbc.M117.801373. Epub 2017 Nov 8.


Sequential chemotherapy/radiotherapy was comparable with concurrent chemoradiotherapy for stage I/II NK/T-cell lymphoma.

Kwong YL, Kim SJ, Tse E, Oh SY, Kwak JY, Eom HS, Do YR, Mun YC, Lee SR, Shin HJ, Suh C, Chuang SS, Lee YS, Lim ST, Izutsu K, Suzuki R, Relander T, d'Amore F, Schmitz N, Jaccard A, Kim WS.

Ann Oncol. 2018 Jan 1;29(1):256-263. doi: 10.1093/annonc/mdx684.


Efficacy and Safety of Mycophenolate Mofetil in Patients With Autoimmune Hepatitis and Suboptimal Outcomes After Standard Therapy.

Roberts SK, Lim R, Strasser S, Nicoll A, Gazzola A, Mitchell J, Siow W, Khoo T, Hamarneh Z, Weltman M, Gow P, Janko N, Tse E, Mishra G, Cheng EH, Levy M, Cheng W, Sood S, Skoien R, Mitchell J, Zekry A, George J, MacQuillan G, Wigg A, Stuart K, Sievert W, McCaughan G; ALA Clinical Research Network.

Clin Gastroenterol Hepatol. 2018 Feb;16(2):268-277. doi: 10.1016/j.cgh.2017.09.063. Epub 2017 Oct 16.


Nuclear Met promotes hepatocellular carcinoma tumorigenesis and metastasis by upregulation of TAK1 and activation of NF-κB pathway.

Tey SK, Tse EYT, Mao X, Ko FCF, Wong AST, Lo RC, Ng IO, Yam JWP.

Cancer Lett. 2017 Dec 28;411:150-161. doi: 10.1016/j.canlet.2017.09.047. Epub 2017 Oct 6.


Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.

Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS.

Cell. 2017 Oct 5;171(2):481-494.e15. doi: 10.1016/j.cell.2017.09.027.


Prevalence of mild behavioral impairment in mild cognitive impairment and subjective cognitive decline, and its association with caregiver burden.

Sheikh F, Ismail Z, Mortby ME, Barber P, Cieslak A, Fischer K, Granger R, Hogan DB, Mackie A, Maxwell CJ, Menon B, Mueller P, Patry D, Pearson D, Quickfall J, Sajobi T, Tse E, Wang M, Smith EE; PROMPT registry investigators.

Int Psychogeriatr. 2018 Feb;30(2):233-244. doi: 10.1017/S104161021700151X. Epub 2017 Sep 7.


PD1 blockade with low-dose nivolumab in NK/T cell lymphoma failing L-asparaginase: efficacy and safety.

Chan TSY, Li J, Loong F, Khong PL, Tse E, Kwong YL.

Ann Hematol. 2018 Jan;97(1):193-196. doi: 10.1007/s00277-017-3127-2. Epub 2017 Sep 6. No abstract available.


The Oxidation State of [4Fe4S] Clusters Modulates the DNA-Binding Affinity of DNA Repair Proteins.

Tse ECM, Zwang TJ, Barton JK.

J Am Chem Soc. 2017 Sep 13;139(36):12784-12792. doi: 10.1021/jacs.7b07230. Epub 2017 Aug 29.


Clinical Practice Recommendations on Indication and Timing of Hematopoietic Cell Transplantation in Mature T Cell and NK/T Cell Lymphomas: An International Collaborative Effort on Behalf of the Guidelines Committee of the American Society for Blood and Marrow Transplantation.

Kharfan-Dabaja MA, Kumar A, Ayala E, Hamadani M, Reimer P, Gisselbrecht C, d'Amore F, Jantunen E, Ishida T, Bazarbachi A, Foss F, Advani R, Fenske TS, Lazarus HM, Friedberg JW, Aljurf M, Sokol L, Tobinai K, Tse E, Burns LJ, Chavez JC, Reddy NM, Suzuki R, Ahmed S, Nademanee A, Mohty M, Gopal AK, Fanale MA, Pro B, Moskowitz AJ, Sureda A, Perales MA, Carpenter PA, Savani BN.

Biol Blood Marrow Transplant. 2017 Nov;23(11):1826-1838. doi: 10.1016/j.bbmt.2017.07.027. Epub 2017 Aug 7.


Positron emission tomography computed tomography features of monomorphic epitheliotropic intestinal T-cell lymphoma.

Chan TSY, Lee E, Khong PL, Tse EWC, Kwong YL.

Hematology. 2018 Jan;23(1):10-16. doi: 10.1080/10245332.2017.1335979. Epub 2017 Jun 5.


Saving costs through a coordinated care model for patients with hepatocellular cancer.

Ow TW, Ralton L, Tse E.

Intern Med J. 2017 Sep;47(9):1005-1011. doi: 10.1111/imj.13465.


Clinicopathological features and outcome of chronic lymphocytic leukaemia in Chinese patients.

Chan TS, Lee YS, Del Giudice I, Marinelli M, Ilari C, Cafforio L, Guarini A, Tan D, Phipps C, Goh YT, Hwang W, Goh AZ, Siu LL, Wu S, Ha CY, Lin SY, Kwok CH, Lau CK, Wong KF, Foà R, Kwong YL, Tse E.

Oncotarget. 2017 Apr 11;8(15):25455-25468. doi: 10.18632/oncotarget.16037.


Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2.

Moffitt AB, Ondrejka SL, McKinney M, Rempel RE, Goodlad JR, Teh CH, Leppa S, Mannisto S, Kovanen PE, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Iqbal J, Yu J, Naresh K, Villa D, Gascoyne RD, Said J, Czader MB, Chadburn A, Richards KL, Rajagopalan D, Davis NS, Smith EC, Palus BC, Tzeng TJ, Healy JA, Lugar PL, Datta J, Love C, Levy S, Dunson DB, Zhuang Y, Hsi ED, Dave SS.

J Exp Med. 2017 May 1;214(5):1371-1386. doi: 10.1084/jem.20160894. Epub 2017 Apr 19.


Real-world efficacy and safety of ritonavir-boosted paritaprevir, ombitasvir, dasabuvir ± ribavirin for hepatitis C genotype 1 - final results of the REV1TAL study.

Lubel J, Strasser S, Stuart KA, Dore G, Thompson A, Pianko S, Bollipo S, Mitchell JL, Fragomeli V, Jones T, Chivers S, Gow P, Iser D, Levy M, Tse E, Gazzola A, Cheng W, Nazareth S, Galhenage S, Wade A, Weltman M, Wigg A, MacQuillan G, Sasadeusz J, George J, Zekry A, Roberts SK; Australian Liver Association Clinical Research Network (ALA CRN).

Antivir Ther. 2017;22(8):699-710. doi: 10.3851/IMP3168.


The diagnosis and management of NK/T-cell lymphomas.

Tse E, Kwong YL.

J Hematol Oncol. 2017 Apr 14;10(1):85. doi: 10.1186/s13045-017-0452-9. Review.


Deficiency of Cks1 Leads to Learning and Long-Term Memory Defects and p27 Dependent Formation of Neuronal Cofilin Aggregates.

Kukalev A, Ng YM, Ju L, Saidi A, Lane S, Mondragon A, Dormann D, Walker SE, Grey W, Ho PW, Stephens DN, Carr AM, Lamsa K, Tse E, Yu VPCC.

Cereb Cortex. 2017 Jan 1;27(1):11-23. doi: 10.1093/cercor/bhw354.


Aggregation of Mod5 is affected by tRNA binding with implications for tRNA gene-mediated silencing.

Read DF, Waller TJ, Tse E, Southworth DR, Engelke DR, Smaldino PJ.

FEBS Lett. 2017 Jun;591(11):1601-1610. doi: 10.1002/1873-3468.12627. Epub 2017 May 22.


Proton transfer dynamics dictate quinone speciation at lipid-modified electrodes.

Tse EC, Barile CJ, Li Y, Zimmerman SC, Hosseini A, Gewirth AA.

Phys Chem Chem Phys. 2017 Mar 8;19(10):7086-7093. doi: 10.1039/c6cp07586j.


PD1 blockade with pembrolizumab is highly effective in relapsed or refractory NK/T-cell lymphoma failing l-asparaginase.

Kwong YL, Chan TSY, Tan D, Kim SJ, Poon LM, Mow B, Khong PL, Loong F, Au-Yeung R, Iqbal J, Phipps C, Tse E.

Blood. 2017 Apr 27;129(17):2437-2442. doi: 10.1182/blood-2016-12-756841. Epub 2017 Feb 10.


Chidamide in the treatment of peripheral T-cell lymphoma.

Chan TS, Tse E, Kwong YL.

Onco Targets Ther. 2017 Jan 12;10:347-352. doi: 10.2147/OTT.S93528. eCollection 2017. Review.


miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression.

Leong KW, Cheng CW, Wong CM, Ng IO, Kwong YL, Tse E.

Oncotarget. 2017 Feb 14;8(7):11343-11355. doi: 10.18632/oncotarget.14526.


Understanding the role of PIN1 in hepatocellular carcinoma.

Cheng CW, Leong KW, Tse E.

World J Gastroenterol. 2016 Dec 7;22(45):9921-9932. doi: 10.3748/wjg.v22.i45.9921. Review.


BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins.

Rauch JN, Tse E, Freilich R, Mok SA, Makley LN, Southworth DR, Gestwicki JE.

J Mol Biol. 2017 Jan 6;429(1):128-141. doi: 10.1016/j.jmb.2016.11.013. Epub 2016 Nov 21.


Arsenic trioxide degrades NPM-ALK fusion protein and inhibits growth of ALK-positive anaplastic large cell lymphoma.

Piao W, Chau D, Yue LM, Kwong YL, Tse E.

Leukemia. 2017 Feb;31(2):522-526. doi: 10.1038/leu.2016.311. Epub 2016 Oct 31. No abstract available.


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