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Best matches for Tschöp MH[au]:

Animal models of obesity and diabetes mellitus. Kleinert M et al. Nat Rev Endocrinol. (2018)

Ghrelin. Müller TD et al. Mol Metab. (2015)

Gut-Brain Cross-Talk in Metabolic Control. Clemmensen C et al. Cell. (2017)

Search results

Items: 1 to 50 of 298

1.

Dusp8 affects hippocampal size and behavior in mice and humans.

Baumann P, Schriever SC, Kullmann S, Zimprich A, Feuchtinger A, Amarie O, Peter A, Walch A, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Wurst W, Tschöp MH, Heni M, Hölter SM, Pfluger PT.

Sci Rep. 2019 Dec 20;9(1):19483. doi: 10.1038/s41598-019-55527-7.

2.

Gut Peptide Agonism in the Treatment of Obesity and Diabetes.

Grandl G, Novikoff A, DiMarchi R, Tschöp MH, Müller TD.

Compr Physiol. 2019 Dec 18;10(1):99-124. doi: 10.1002/cphy.c180044.

PMID:
31853954
3.

The Role of Tactile Stimulation for Expectation, Perceived Treatment Assignment and the Placebo Effect in an Experimental Nausea Paradigm.

Aichner S, Haile A, Hoffmann V, Olliges E, Tschöp MH, Meissner K.

Front Neurosci. 2019 Nov 13;13:1212. doi: 10.3389/fnins.2019.01212. eCollection 2019.

4.

Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates.

Knerr PJ, Mowery SA, Finan B, Perez-Tilve D, Tschöp MH, DiMarchi RD.

Peptides. 2019 Nov 28:170225. doi: 10.1016/j.peptides.2019.170225. [Epub ahead of print] Review.

PMID:
31786282
5.

Glucagon-like peptide 1 (GLP-1).

Müller TD, Finan B, Bloom SR, D'Alessio D, Drucker DJ, Flatt PR, Fritsche A, Gribble F, Grill HJ, Habener JF, Holst JJ, Langhans W, Meier JJ, Nauck MA, Perez-Tilve D, Pocai A, Reimann F, Sandoval DA, Schwartz TW, Seeley RJ, Stemmer K, Tang-Christensen M, Woods SC, DiMarchi RD, Tschöp MH.

Mol Metab. 2019 Dec;30:72-130. doi: 10.1016/j.molmet.2019.09.010. Epub 2019 Sep 30. Review.

6.

Corrigendum to "Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood-brain barrier in leptin resistant mice" [Molecular Metabolism 13 (2018) 77-82].

Kleinert M, Kotzbeck P, Altendorfer-Kroath T, Birngruber T, Tschöp MH, Clemmensen C.

Mol Metab. 2019 Dec;30:265. doi: 10.1016/j.molmet.2019.11.001. No abstract available.

7.

Corrigendum to "Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice" [Molecular Metabolism 23 (2019) 75-81].

Jall S, Finan B, Collden G, Fischer K, Dong X, Tschöp MH, Müller TD, Clemmensen C.

Mol Metab. 2019 Dec;30:264. doi: 10.1016/j.molmet.2019.11.002. No abstract available.

8.

Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation.

Lundsgaard AM, Fritzen AM, Nicolaisen TS, Carl CS, Sjøberg KA, Raun SH, Klein AB, Sanchez-Quant E, Langer J, Ørskov C, Clemmensen C, Tschöp MH, Richter EA, Kiens B, Kleinert M.

J Lipid Res. 2020 Jan;61(1):10-19. doi: 10.1194/jlr.RA119000177. Epub 2019 Nov 12.

PMID:
31719103
9.

The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.

Herrera Moro Chao D, Wang Y, Foppen E, Ottenhoff R, van Roomen C, Parlevliet ET, van Eijk M, Verhoek M, Boot R, Marques AR, Scheij S, Mirzaian M, Kooijman S, Jansen K, Wang D, Mergen C, Seeley RJ, Tschöp MH, Overkleeft H, Rensen PCN, Kalsbeek A, Aerts JMFG, Yi CX.

Diabetes. 2019 Dec;68(12):2223-2234. doi: 10.2337/db19-0049. Epub 2019 Oct 2.

PMID:
31578192
10.

Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults.

Körner A, Tschöp MH, Blüher M.

N Engl J Med. 2019 Aug 29;381(9):e17. doi: 10.1056/NEJMc1908751. No abstract available.

PMID:
31461607
11.

Short-term cold exposure supports human Treg induction in vivo.

Becker M, Serr I, Salb VK, Ott VB, Mengel L, Blüher M, Weigmann B, Hauner H, Tschöp MH, Daniel C.

Mol Metab. 2019 Oct;28:73-82. doi: 10.1016/j.molmet.2019.08.002. Epub 2019 Aug 5.

12.

CNS-targeting pharmacological interventions for the metabolic syndrome.

Stemmer K, Müller TD, DiMarchi RD, Pfluger PT, Tschöp MH.

J Clin Invest. 2019 Aug 5;130:4058-4071. doi: 10.1172/JCI129195. eCollection 2019 Aug 5. Review.

13.

[Incretin-based co- and tri-agonists : Innovative polypharmacology for the treatment of obesity and diabetes].

Harger A, Stemmer K, Tschöp MH, Müller TD.

Internist (Berl). 2019 Sep;60(9):895-902. doi: 10.1007/s00108-019-0649-9. Review. German.

PMID:
31346639
14.

Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.

von Gamm M, Schaub A, Jones AN, Wolf C, Behrens G, Lichti J, Essig K, Macht A, Pircher J, Ehrlich A, Davari K, Chauhan D, Busch B, Wurst W, Feederle R, Feuchtinger A, Tschöp MH, Friedel CC, Hauck SM, Sattler M, Geerlof A, Hornung V, Heissmeyer V, Schulz C, Heikenwalder M, Glasmacher E.

J Exp Med. 2019 Jul 1;216(7):1700-1723. doi: 10.1084/jem.20181762. Epub 2019 May 24.

15.

Chip-based sensing for release of unprocessed cell surface proteins in vitro and in serum and its (patho)physiological relevance.

Müller GA, Herling AW, Stemmer K, Lechner A, Tschöp MH.

Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E212-E233. doi: 10.1152/ajpendo.00079.2019. Epub 2019 Apr 30.

PMID:
31039006
16.

GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice.

Décarie-Spain L, Fisette A, Zhu Z, Yang B, DiMarchi RD, Tschöp MH, Finan B, Fulton S, Clemmensen C.

Neuropharmacology. 2019 Jun;151:55-63. doi: 10.1016/j.neuropharm.2019.03.035. Epub 2019 Apr 1.

PMID:
30946847
17.

Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway.

Ratner C, He Z, Grunddal KV, Skov LJ, Hartmann B, Zhang F, Feuchtinger A, Bjerregaard A, Christoffersen C, Tschöp MH, Finan B, DiMarchi RD, Leinninger GM, Williams KW, Clemmensen C, Holst B.

Diabetes. 2019 Jun;68(6):1329-1340. doi: 10.2337/db18-1009. Epub 2019 Apr 1.

18.

Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice.

Jall S, Finan B, Collden G, Fischer K, Dong X, Tschöp MH, Müller TD, Clemmensen C.

Mol Metab. 2019 May;23:75-81. doi: 10.1016/j.molmet.2019.02.011. Epub 2019 Mar 7. Erratum in: Mol Metab. 2019 Dec;30:264.

19.

Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease.

Niu L, Geyer PE, Wewer Albrechtsen NJ, Gluud LL, Santos A, Doll S, Treit PV, Holst JJ, Knop FK, Vilsbøll T, Junker A, Sachs S, Stemmer K, Müller TD, Tschöp MH, Hofmann SM, Mann M.

Mol Syst Biol. 2019 Mar 1;15(3):e8793. doi: 10.15252/msb.20188793.

20.

Erratum. Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1. Diabetes 2018;67:2456-2465.

Pfuhlmann K, Schriever SC, Baumann P, Kabra DG, Harrison L, Mazibuko-Mbeje SE, Contreras RE, Kyriakou E, Simonds SE, Tiganis T, Cowley MA, Woods SC, Jastroch M, Clemmensen C, De Angelis M, Schramm KW, Sattler M, Messias AC, Tschöp MH, Pfluger PT.

Diabetes. 2019 Mar;68(3):676. doi: 10.2337/db19-er03a. Epub 2019 Jan 11. No abstract available.

21.

Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism.

Mroz PA, Finan B, Gelfanov V, Yang B, Tschöp MH, DiMarchi RD, Perez-Tilve D.

Mol Metab. 2019 Feb;20:51-62. doi: 10.1016/j.molmet.2018.12.001. Epub 2018 Dec 5.

22.

Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism.

García-Cáceres C, Balland E, Prevot V, Luquet S, Woods SC, Koch M, Horvath TL, Yi CX, Chowen JA, Verkhratsky A, Araque A, Bechmann I, Tschöp MH.

Nat Neurosci. 2019 Jan;22(1):7-14. doi: 10.1038/s41593-018-0286-y. Epub 2018 Dec 10. Review.

PMID:
30531847
23.

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.

Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC.

J Med Chem. 2018 Dec 27;61(24):11144-11157. doi: 10.1021/acs.jmedchem.8b01224. Epub 2018 Dec 7.

PMID:
30525586
24.

Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.

Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH.

Nat Commun. 2018 Nov 20;9(1):4975. doi: 10.1038/s41467-018-07479-1.

25.

Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases.

Clemmensen C, Finan B, Müller TD, DiMarchi RD, Tschöp MH, Hofmann SM.

Nat Rev Endocrinol. 2019 Feb;15(2):90-104. doi: 10.1038/s41574-018-0118-x. Review.

PMID:
30446744
26.

Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.

Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH.

Nat Commun. 2018 Oct 23;9(1):4304. doi: 10.1038/s41467-018-06769-y. Erratum in: Nat Commun. 2018 Nov 20;9(1):4975.

27.

Fluorescent blood-brain barrier tracing shows intact leptin transport in obese mice.

Harrison L, Schriever SC, Feuchtinger A, Kyriakou E, Baumann P, Pfuhlmann K, Messias AC, Walch A, Tschöp MH, Pfluger PT.

Int J Obes (Lond). 2019 Jun;43(6):1305-1318. doi: 10.1038/s41366-018-0221-z. Epub 2018 Oct 3.

28.

Peptide-based multi-agonists: a new paradigm in metabolic pharmacology.

Brandt SJ, Müller TD, DiMarchi RD, Tschöp MH, Stemmer K.

J Intern Med. 2018 Dec;284(6):581-602. doi: 10.1111/joim.12837. Epub 2018 Oct 23. Review.

PMID:
30230640
29.

Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks.

Dyar KA, Lutter D, Artati A, Ceglia NJ, Liu Y, Armenta D, Jastroch M, Schneider S, de Mateo S, Cervantes M, Abbondante S, Tognini P, Orozco-Solis R, Kinouchi K, Wang C, Swerdloff R, Nadeef S, Masri S, Magistretti P, Orlando V, Borrelli E, Uhlenhaut NH, Baldi P, Adamski J, Tschöp MH, Eckel-Mahan K, Sassone-Corsi P.

Cell. 2018 Sep 6;174(6):1571-1585.e11. doi: 10.1016/j.cell.2018.08.042.

30.

Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.

Pfuhlmann K, Schriever SC, Baumann P, Kabra DG, Harrison L, Mazibuko-Mbeje SE, Contreras RE, Kyriakou E, Simonds SE, Tiganis T, Cowley MA, Woods SC, Jastroch M, Clemmensen C, De Angelis M, Schramm KW, Sattler M, Messias AC, Tschöp MH, Pfluger PT.

Diabetes. 2018 Nov;67(11):2456-2465. doi: 10.2337/db18-0146. Epub 2018 Aug 28. Erratum in: Diabetes. 2019 Mar;68(3):676.

31.

Chronic d-serine supplementation impairs insulin secretion.

Suwandhi L, Hausmann S, Braun A, Gruber T, Heinzmann SS, Gálvez EJC, Buck A, Legutko B, Israel A, Feuchtinger A, Haythorne E, Staiger H, Heni M, Häring HU, Schmitt-Kopplin P, Walch A, Cáceres CG, Tschöp MH, Rutter GA, Strowig T, Elsner M, Ussar S.

Mol Metab. 2018 Oct;16:191-202. doi: 10.1016/j.molmet.2018.07.002. Epub 2018 Jul 25.

32.

Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.

Müller TD, Clemmensen C, Finan B, DiMarchi RD, Tschöp MH.

Pharmacol Rev. 2018 Oct;70(4):712-746. doi: 10.1124/pr.117.014803. Review.

PMID:
30087160
33.

An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation.

Khajavi N, Finan B, Kluth O, Müller TD, Mergler S, Schulz A, Kleinau G, Scheerer P, Schürmann A, Gudermann T, Tschöp MH, Krude H, DiMarchi RD, Biebermann H.

Cell Signal. 2018 Nov;51:13-22. doi: 10.1016/j.cellsig.2018.07.006. Epub 2018 Jul 25.

PMID:
30055232
34.

Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.

Nikolakopoulou P, Chatzigeorgiou A, Kourtzelis I, Toutouna L, Masjkur J, Arps-Forker C, Poser SW, Rozman J, Rathkolb B, Aguilar-Pimentel JA; German Mouse Clinic Consortium, Wolf E, Klingenspor M, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Tsata V, Monasor LS, Troullinaki M, Witt A, Anastasiou V, Chrousos G, Yi CX, García-Cáceres C, Tschöp MH, Bornstein SR, Androutsellis-Theotokis A.

Sci Rep. 2018 Jul 27;8(1):11335. doi: 10.1038/s41598-018-29434-2.

35.

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.

Renner S, Blutke A, Dobenecker B, Dhom G, Müller TD, Finan B, Clemmensen C, Bernau M, Novak I, Rathkolb B, Senf S, Zöls S, Roth M, Götz A, Hofmann SM, Hrabĕ de Angelis M, Wanke R, Kienzle E, Scholz AM, DiMarchi R, Ritzmann M, Tschöp MH, Wolf E.

Mol Metab. 2018 Oct;16:180-190. doi: 10.1016/j.molmet.2018.06.015. Epub 2018 Jun 28.

36.

Circulating HDL levels control hypothalamic astrogliosis via apoA-I.

Götz A, Lehti M, Donelan E, Striese C, Cucuruz S, Sachs S, Yi CX, Woods SC, Wright SD, Müller TD, Tschöp MH, Gao Y, Hofmann SM.

J Lipid Res. 2018 Sep;59(9):1649-1659. doi: 10.1194/jlr.M085456. Epub 2018 Jul 10.

37.

Targeting the Incretin/Glucagon System With Triagonists to Treat Diabetes.

Capozzi ME, DiMarchi RD, Tschöp MH, Finan B, Campbell JE.

Endocr Rev. 2018 Oct 1;39(5):719-738. doi: 10.1210/er.2018-00117. Review.

PMID:
29905825
38.

Are peptide conjugates the golden therapy against obesity?

Brandt SJ, Kleinert M, Tschöp MH, Müller TD.

J Endocrinol. 2018 Aug;238(2):R109-R119. doi: 10.1530/JOE-18-0264. Epub 2018 May 30. Review.

39.

Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood-brain barrier in leptin resistant mice.

Kleinert M, Kotzbeck P, Altendorfer-Kroath T, Birngruber T, Tschöp MH, Clemmensen C.

Mol Metab. 2018 Jul;13:77-82. doi: 10.1016/j.molmet.2018.04.008. Epub 2018 Apr 27. Erratum in: Mol Metab. 2019 Dec;30:265.

40.

Adipocyte p62/SQSTM1 Suppresses Tumorigenesis through Opposite Regulations of Metabolism in Adipose Tissue and Tumor.

Huang J, Duran A, Reina-Campos M, Valencia T, Castilla EA, Müller TD, Tschöp MH, Moscat J, Diaz-Meco MT.

Cancer Cell. 2018 Apr 9;33(4):770-784.e6. doi: 10.1016/j.ccell.2018.03.001.

41.

Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice.

Pfuhlmann K, Schriever SC, Legutko B, Baumann P, Harrison L, Kabra DG, Baumgart EV, Tschöp MH, Garcia-Caceres C, Pfluger PT.

J Neuroinflammation. 2018 Feb 8;15(1):35. doi: 10.1186/s12974-018-1076-x.

42.

Ghrelin regulation of glucose metabolism.

Poher AL, Tschöp MH, Müller TD.

Peptides. 2018 Feb;100:236-242. doi: 10.1016/j.peptides.2017.12.015. Review.

43.

Gut hormone polyagonists for the treatment of type 2 diabetes.

Brandt SJ, Götz A, Tschöp MH, Müller TD.

Peptides. 2018 Feb;100:190-201. doi: 10.1016/j.peptides.2017.12.021. Review.

44.

Animal models of obesity and diabetes mellitus.

Kleinert M, Clemmensen C, Hofmann SM, Moore MC, Renner S, Woods SC, Huypens P, Beckers J, de Angelis MH, Schürmann A, Bakhti M, Klingenspor M, Heiman M, Cherrington AD, Ristow M, Lickert H, Wolf E, Havel PJ, Müller TD, Tschöp MH.

Nat Rev Endocrinol. 2018 Mar;14(3):140-162. doi: 10.1038/nrendo.2017.161. Epub 2018 Jan 19. Review.

45.

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Rozman J, Rathkolb B, Oestereicher MA, Schütt C, Ravindranath AC, Leuchtenberger S, Sharma S, Kistler M, Willershäuser M, Brommage R, Meehan TF, Mason J, Haselimashhadi H; IMPC Consortium, Hough T, Mallon AM, Wells S, Santos L, Lelliott CJ, White JK, Sorg T, Champy MF, Bower LR, Reynolds CL, Flenniken AM, Murray SA, Nutter LMJ, Svenson KL, West D, Tocchini-Valentini GP, Beaudet AL, Bosch F, Braun RB, Dobbie MS, Gao X, Herault Y, Moshiri A, Moore BA, Kent Lloyd KC, McKerlie C, Masuya H, Tanaka N, Flicek P, Parkinson HE, Sedlacek R, Seong JK, Wang CL, Moore M, Brown SD, Tschöp MH, Wurst W, Klingenspor M, Wolf E, Beckers J, Machicao F, Peter A, Staiger H, Häring HU, Grallert H, Campillos M, Maier H, Fuchs H, Gailus-Durner V, Werner T, Hrabe de Angelis M.

Nat Commun. 2018 Jan 18;9(1):288. doi: 10.1038/s41467-017-01995-2.

46.

Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.

Balsevich G, Häusl AS, Meyer CW, Karamihalev S, Feng X, Pöhlmann ML, Dournes C, Uribe-Marino A, Santarelli S, Labermaier C, Hafner K, Mao T, Breitsamer M, Theodoropoulou M, Namendorf C, Uhr M, Paez-Pereda M, Winter G, Hausch F, Chen A, Tschöp MH, Rein T, Gassen NC, Schmidt MV.

Nat Commun. 2017 Nov 23;8(1):1725. doi: 10.1038/s41467-017-01783-y.

47.

Optimization of peptide-based polyagonists for treatment of diabetes and obesity.

Knerr PJ, Finan B, Gelfanov V, Perez-Tilve D, Tschöp MH, DiMarchi RD.

Bioorg Med Chem. 2018 Jun 1;26(10):2873-2881. doi: 10.1016/j.bmc.2017.10.047. Epub 2017 Nov 2. Review. No abstract available.

PMID:
29153547
48.

Erratum. Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition. Diabetes 2017;66:272-286.

Mueller KM, Hartmann K, Kaltenecker D, Vettorazzi S, Bauer M, Mauser L, Amann S, Jall S, Fischer K, Esterbauer H, Müller TD, Tschöp MH, Magnes C, Haybaeck J, Scherer T, Bordag N, Tuckermann JP, Moriggl R.

Diabetes. 2018 Feb;67(2):343-344. doi: 10.2337/db18-er02a. Epub 2017 Nov 16. No abstract available.

49.

A Synaptic Basis for GLP-1 Action in the Brain.

Lefort S, Tschöp MH, García-Cáceres C.

Neuron. 2017 Nov 15;96(4):713-715. doi: 10.1016/j.neuron.2017.10.034.

50.

Dietary Manipulations That Induce Ketosis Activate the HPA Axis in Male Rats and Mice: A Potential Role for Fibroblast Growth Factor-21.

Ryan KK, Packard AEB, Larson KR, Stout J, Fourman SM, Thompson AMK, Ludwick K, Habegger KM, Stemmer K, Itoh N, Perez-Tilve D, Tschöp MH, Seeley RJ, Ulrich-Lai YM.

Endocrinology. 2018 Jan 1;159(1):400-413. doi: 10.1210/en.2017-00486.

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