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Items: 12

1.

Discovery of novel inhibitors for DHODH via virtual screening and X-ray crystallographic structures.

McLean LR, Zhang Y, Degnen W, Peppard J, Cabel D, Zou C, Tsay JT, Subramaniam A, Vaz RJ, Li Y.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1981-4. doi: 10.1016/j.bmcl.2010.01.115. Epub 2010 Jan 25.

PMID:
20153645
2.

Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening.

McLean LR, Zhang Y, Li H, Li Z, Lukasczyk U, Choi YM, Han Z, Prisco J, Fordham J, Tsay JT, Reiling S, Vaz RJ, Li Y.

Bioorg Med Chem Lett. 2009 Dec 1;19(23):6717-20. doi: 10.1016/j.bmcl.2009.09.106. Epub 2009 Oct 1.

PMID:
19836948
3.

Crystal structure of human cyclin-dependent kinase 2 in complex with the adenine-derived inhibitor H717.

Dreyer MK, Borcherding DR, Dumont JA, Peet NP, Tsay JT, Wright PS, Bitonti AJ, Shen J, Kim SH.

J Med Chem. 2001 Feb 15;44(4):524-30.

PMID:
11170642
4.

Strategies for optimal synthesis and secretion of heterologous proteins in the methylotrophic yeast Pichia pastoris.

Sreekrishna K, Brankamp RG, Kropp KE, Blankenship DT, Tsay JT, Smith PL, Wierschke JD, Subramaniam A, Birkenberger LA.

Gene. 1997 Apr 29;190(1):55-62.

PMID:
9185849
5.
6.

Thiolactomycin resistance in Escherichia coli is associated with the multidrug resistance efflux pump encoded by emrAB.

Furukawa H, Tsay JT, Jackowski S, Takamura Y, Rock CO.

J Bacteriol. 1993 Jun;175(12):3723-9.

8.

Isolation and characterization of the beta-ketoacyl-acyl carrier protein synthase III gene (fabH) from Escherichia coli K-12.

Tsay JT, Oh W, Larson TJ, Jackowski S, Rock CO.

J Biol Chem. 1992 Apr 5;267(10):6807-14.

10.

Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase.

Tsay JT, Appleman JR, Beard WA, Prendergast NJ, Delcamp TJ, Freisheim JH, Blakley RL.

Biochemistry. 1990 Jul 10;29(27):6428-36.

PMID:
2207084
11.

pK values for active site residues of carboxypeptidase A.

Mock WL, Tsay JT.

J Biol Chem. 1988 Jun 25;263(18):8635-41.

12.

A probe of the active site acidity of carboxypeptidase A.

Mock WL, Tsay JT.

Biochemistry. 1986 May 20;25(10):2920-7.

PMID:
3718930

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