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Items: 1 to 50 of 366

1.

Epstein-Barr Virus BART Long Non-coding RNAs Function as Epigenetic Modulators in Nasopharyngeal Carcinoma.

Verhoeven RJA, Tong S, Mok BW, Liu J, He S, Zong J, Chen Y, Tsao SW, Lung ML, Chen H.

Front Oncol. 2019 Oct 22;9:1120. doi: 10.3389/fonc.2019.01120. eCollection 2019.

2.

Integration of biochemical and topographic cues for the formation and spatial distribution of invadosomes in nasopharyngeal epithelial cells.

Tsang CM, Liu ZY, Zhang W, You C, Jones GE, Tsao SW, Pang SW.

Acta Biomater. 2019 Nov 1. pii: S1742-7061(19)30731-7. doi: 10.1016/j.actbio.2019.10.043. [Epub ahead of print]

3.

miR-338-5p reverses chemoresistance and inhibits invasion of esophageal squamous cell carcinoma cells via targeting Id-1.

Han L, Cui D, Li B, Xu WW, Lam AKY, Chan KT, Zhu Y, Lee NPY, Law SY, Guan XY, Qin YR, Chan KW, Ma S, Tsao SW, Cheung ALM.

Cancer Sci. 2019 Oct 23. doi: 10.1111/cas.14220. [Epub ahead of print]

4.

CHL1 suppresses tumor growth and metastasis in nasopharyngeal carcinoma by repressing PI3K/AKT signaling pathway via interaction with Integrin β1 and Merlin.

Chen J, Jiang C, Fu L, Zhu CL, Xiang YQ, Jiang LX, Chen Q, Liu WM, Chen JN, Zhang LY, Liu M, Chen C, Tang H, Wang B, Tsao SW, Kwong DL, Guan XY.

Int J Biol Sci. 2019 Jul 11;15(9):1802-1815. doi: 10.7150/ijbs.34785. eCollection 2019.

5.

Epstein-Barr virus ncRNA from a nasopharyngeal carcinoma induces an inflammatory response that promotes virus production.

Li Z, Tsai MH, Shumilov A, Baccianti F, Tsao SW, Poirey R, Delecluse HJ.

Nat Microbiol. 2019 Sep 9. doi: 10.1038/s41564-019-0546-y. [Epub ahead of print]

PMID:
31501540
6.

The anti-tumor function of the IKK inhibitor PS1145 and high levels of p65 and KLF4 are associated with the drug resistance in nasopharyngeal carcinoma cells.

Lung HL, Kan R, Chau WY, Man OY, Mak NK, Fong CH, Shuen WH, Tsao SW, Lung ML.

Sci Rep. 2019 Aug 19;9(1):12064. doi: 10.1038/s41598-019-48590-7.

7.

Identification of ARKL1 as a Negative Regulator of Epstein-Barr Virus Reactivation.

Siddiqi UZ, Vaidya AS, Li X, Marcon E, Tsao SW, Greenblatt J, Frappier L.

J Virol. 2019 Sep 30;93(20). pii: e00989-19. doi: 10.1128/JVI.00989-19. Print 2019 Oct 15.

PMID:
31341047
8.

EBV infection is associated with histone bivalent switch modifications in squamous epithelial cells.

Leong MML, Cheung AKL, Dai W, Tsao SW, Tsang CM, Dawson CW, Mun Yee Ko J, Lung ML.

Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14144-14153. doi: 10.1073/pnas.1821752116. Epub 2019 Jun 24.

PMID:
31235597
9.

Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma.

Wang C, Jiang S, Ke L, Zhang L, Li D, Liang J, Narita Y, Hou I, Chen CH, Wang L, Zhong Q, Ling Y, Lv X, Xiang Y, Guo X, Teng M, Tsao SW, Gewurz BE, Zeng MS, Zhao B.

J Biol Chem. 2019 Jun 21;294(25):9734-9745. doi: 10.1074/jbc.RA119.008793. Epub 2019 May 9.

PMID:
31073033
10.

Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance.

Li B, Hong P, Zheng CC, Dai W, Chen WY, Yang QS, Han L, Tsao SW, Chan KT, Lee NPY, Law S, Xu LY, Li EM, Chan KW, Qin YR, Guan XY, Lung ML, He QY, Xu WW, Cheung AL.

Theranostics. 2019 Feb 28;9(6):1599-1613. doi: 10.7150/thno.30372. eCollection 2019.

11.

Defining early events of Epstein-Barr virus (EBV) infection in immortalized nasopharyngeal epithelial cells using cell-free EBV infection.

Pang PS, Liu T, Lin W, Tsang CM, Yip YL, Zhou Y, Guan XY, Chan RC, Tsao SW, Deng W.

J Gen Virol. 2019 Jun;100(6):999-1012. doi: 10.1099/jgv.0.001243. Epub 2019 Feb 28.

PMID:
30816843
12.

mTORC2-mediated PDHE1α nuclear translocation links EBV-LMP1 reprogrammed glucose metabolism to cancer metastasis in nasopharyngeal carcinoma.

Zhang J, Jia L, Liu T, Yip YL, Tang WC, Lin W, Deng W, Lo KW, You C, Lung ML, Lung HL, Cheung AL, Tsao SW, Tsang CM.

Oncogene. 2019 Jun;38(24):4669-4684. doi: 10.1038/s41388-019-0749-y. Epub 2019 Feb 11.

13.

Geopolymer technology for the solidification of simulated ion exchange resins with radionuclides.

Lee WH, Cheng TW, Ding YC, Lin KL, Tsao SW, Huang CP.

J Environ Manage. 2019 Apr 1;235:19-27. doi: 10.1016/j.jenvman.2019.01.027. Epub 2019 Jan 19.

PMID:
30669089
14.

Effect of a Qigong Intervention on Telomerase Activity and Mental Health in Chinese Women Survivors of Intimate Partner Violence: A Randomized Clinical Trial.

Cheung DST, Deng W, Tsao SW, Ho RTH, Chan CLW, Fong DYT, Chau PH, Hong AWL, Fung HYKY, Ma JLC, Tiwari AFY.

JAMA Netw Open. 2019 Jan 4;2(1):e186967. doi: 10.1001/jamanetworkopen.2018.6967.

15.

EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma.

Lyu X, Wang J, Guo X, Wu G, Jiao Y, Faleti OD, Liu P, Liu T, Long Y, Chong T, Yang X, Huang J, He M, Tsang CM, Tsao SW, Wang Q, Jiang Q, Li X.

PLoS Pathog. 2018 Dec 17;14(12):e1007484. doi: 10.1371/journal.ppat.1007484. eCollection 2018 Dec.

16.

High risk Epstein-Barr virus variants characterized by distinct polymorphisms in the EBER locus are strongly associated with nasopharyngeal carcinoma.

Hui KF, Chan TF, Yang W, Shen JJ, Lam KP, Kwok H, Sham PC, Tsao SW, Kwong DL, Lung ML, Chiang AKS.

Int J Cancer. 2019 Jun 15;144(12):3031-3042. doi: 10.1002/ijc.32049. Epub 2019 Jan 7.

PMID:
30536939
17.

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma.

Lin W, Yip YL, Jia L, Deng W, Zheng H, Dai W, Ko JMY, Lo KW, Chung GTY, Yip KY, Lee SD, Kwan JS, Zhang J, Liu T, Chan JY, Kwong DL, Lee VH, Nicholls JM, Busson P, Liu X, Chiang AKS, Hui KF, Kwok H, Cheung ST, Cheung YC, Chan CK, Li B, Cheung AL, Hau PM, Zhou Y, Tsang CM, Middeldorp J, Chen H, Lung ML, Tsao SW.

Nat Commun. 2018 Nov 7;9(1):4663. doi: 10.1038/s41467-018-06889-5.

18.

Effects of Brimonidine on Retinal Pigment Epithelial Cells and Müller Cells Exposed to Amyloid-Beta 1-42 Peptide In Vitro.

Tsao SW, Gabriel R, Thaker K, Kuppermann BD, Kenney MC.

Ophthalmic Surg Lasers Imaging Retina. 2018 Oct 15;49(10):S23-S28. doi: 10.3928/23258160-20180814-04.

PMID:
30339264
19.

Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein-Barr virus reactivation.

Yip YL, Lin W, Deng W, Jia L, Lo KW, Busson P, Vérillaud B, Liu X, Tsang CM, Lung ML, Tsao SW.

Lab Invest. 2018 Aug;98(8):1093-1104. doi: 10.1038/s41374-018-0034-7. Epub 2018 May 16.

20.

NF-κB Signaling Regulates Epstein-Barr Virus BamHI-Q-Driven EBNA1 Expression.

Verhoeven RJA, Tong S, Zong J, Chen Y, Tsao SW, Pan J, Chen H.

Cancers (Basel). 2018 Apr 16;10(4). pii: E119. doi: 10.3390/cancers10040119.

21.

Interplay of Viral Infection, Host Cell Factors and Tumor Microenvironment in the Pathogenesis of Nasopharyngeal Carcinoma.

Huang SCM, Tsao SW, Tsang CM.

Cancers (Basel). 2018 Apr 4;10(4). pii: E106. doi: 10.3390/cancers10040106. Review.

22.

IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness.

Xu WW, Li B, Zhao JF, Yang JG, Li JQ, Tsao SW, He QY, Cheung ALM.

Cancer Lett. 2018 Jul 1;425:88-100. doi: 10.1016/j.canlet.2018.03.039. Epub 2018 Mar 29.

PMID:
29604392
23.

Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells.

Wang X, Jin DY, Wong YC, Cheung ALM, Chun ACS, Lo AKF, Liu Y, Tsao SW.

Carcinogenesis. 2018 Feb 9;39(2):305. doi: 10.1093/carcin/bgx127. No abstract available.

PMID:
29267852
24.

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

Lung RW, Hau PM, Yu KH, Yip KY, Tong JH, Chak WP, Chan AW, Lam KH, Lo AK, Tin EK, Chau SL, Pang JC, Kwan JS, Busson P, Young LS, Yap LF, Tsao SW, To KF, Lo KW.

J Pathol. 2018 Apr;244(4):394-407. doi: 10.1002/path.5018. Epub 2018 Feb 16.

25.

Epstein-Barr Virus Hijacks DNA Damage Response Transducers to Orchestrate Its Life Cycle.

Hau PM, Tsao SW.

Viruses. 2017 Nov 16;9(11). pii: E341. doi: 10.3390/v9110341. Review.

26.

EBV Infection and Glucose Metabolism in Nasopharyngeal Carcinoma.

Zhang J, Jia L, Tsang CM, Tsao SW.

Adv Exp Med Biol. 2017;1018:75-90. doi: 10.1007/978-981-10-5765-6_6. Review.

PMID:
29052133
27.

Corrigendum: Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells.

Wang X, Jin DY, Wong YC, Cheung ALM, Chun ACS, Lo AKF, Liu Y, Tsao SW.

Carcinogenesis. 2017 Oct 26;38(11):1155. doi: 10.1093/carcin/bgx086. No abstract available. Erratum in: Carcinogenesis. 2018 Feb 9;39(2):305.

PMID:
29028969
28.

Overexpression of F-box only protein 31 predicts poor prognosis and deregulates p38α- and JNK-mediated apoptosis in esophageal squamous cell carcinoma.

Liu J, Lv L, Gong J, Tan Y, Zhu Y, Dai Y, Pan X, Huen MSY, Li B, Tsao SW, Huo J, Cheung ALM.

Int J Cancer. 2018 Jan 1;142(1):145-155. doi: 10.1002/ijc.31040. Epub 2017 Sep 28.

29.

Epstein-Barr virus infection and nasopharyngeal carcinoma.

Tsao SW, Tsang CM, Lo KW.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732). pii: 20160270. doi: 10.1098/rstb.2016.0270. Review.

30.

Loss of ΔNp63α promotes mitotic exit in epithelial cells.

Hau PM, Yip YL, Huen MSY, Tsao SW.

FEBS Lett. 2017 Jun;591(11):1624. doi: 10.1002/1873-3468.12674. No abstract available.

31.

Epstein-Barr Virus Rta-Mediated Accumulation of DNA Methylation Interferes with CTCF Binding in both Host and Viral Genomes.

Chen YJ, Chen YL, Chang Y, Wu CC, Ko YC, Tsao SW, Chen JY, Lin SF.

J Virol. 2017 Jul 12;91(15). pii: e00736-17. doi: 10.1128/JVI.00736-17. Print 2017 Aug 1.

32.

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy.

Li B, Xu WW, Lam AKY, Wang Y, Hu HF, Guan XY, Qin YR, Saremi N, Tsao SW, He QY, Cheung ALM.

Oncotarget. 2017 Jun 13;8(24):38755-38766. doi: 10.18632/oncotarget.16333.

33.

MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF.

Li B, Xu WW, Han L, Chan KT, Tsao SW, Lee NPY, Law S, Xu LY, Li EM, Chan KW, Qin YR, Guan XY, He QY, Cheung ALM.

Oncogene. 2017 Jul 13;36(28):3986-4000. doi: 10.1038/onc.2017.29. Epub 2017 Mar 13.

34.

Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3.

Lee HM, Lo KW, Wei W, Tsao SW, Chung GTY, Ibrahim MH, Dawson CW, Murray PG, Paterson IC, Yap LF.

J Pathol. 2017 May;242(1):62-72. doi: 10.1002/path.4879. Epub 2017 Mar 15.

35.

Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression.

Xu WW, Li B, Guan XY, Chung SK, Wang Y, Yip YL, Law SY, Chan KT, Lee NP, Chan KW, Xu LY, Li EM, Tsao SW, He QY, Cheung AL.

Nat Commun. 2017 Feb 10;8:14399. doi: 10.1038/ncomms14399.

36.

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations.

Li YY, Chung GT, Lui VW, To KF, Ma BB, Chow C, Woo JK, Yip KY, Seo J, Hui EP, Mak MK, Rusan M, Chau NG, Or YY, Law MH, Law PP, Liu ZW, Ngan HL, Hau PM, Verhoeft KR, Poon PH, Yoo SK, Shin JY, Lee SD, Lun SW, Jia L, Chan AW, Chan JY, Lai PB, Fung CY, Hung ST, Wang L, Chang AM, Chiosea SI, Hedberg ML, Tsao SW, van Hasselt AC, Chan AT, Grandis JR, Hammerman PS, Lo KW.

Nat Commun. 2017 Jan 18;8:14121. doi: 10.1038/ncomms14121.

37.

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways.

Zhang J, Jia L, Lin W, Yip YL, Lo KW, Lau VMY, Zhu D, Tsang CM, Zhou Y, Deng W, Lung HL, Lung ML, Cheung LM, Tsao SW.

J Virol. 2017 Feb 28;91(6). pii: e02168-16. doi: 10.1128/JVI.02168-16. Print 2017 Mar 15.

38.

Age-Stratified Analysis of Diabetes and Pseudophakia Effects on Corneal Endothelial Cell Density: A Retrospective Eye Bank Study.

Chen Y, Tsao SW, Heo M, Gore PK, McCarthy MD, Chuck RS, Channa P.

Cornea. 2017 Mar;36(3):367-371. doi: 10.1097/ICO.0000000000001107.

39.

Berberine Suppresses Cyclin D1 Expression through Proteasomal Degradation in Human Hepatoma Cells.

Wang N, Wang X, Tan HY, Li S, Tsang CM, Tsao SW, Feng Y.

Int J Mol Sci. 2016 Nov 15;17(11). pii: E1899.

40.

Upregulation of glycolysis and oxidative phosphorylation in benzo[α]pyrene and arsenic-induced rat lung epithelial transformed cells.

Chen H, Lee LS, Li G, Tsao SW, Chiu JF.

Oncotarget. 2016 Jun 28;7(26):40674-40689. doi: 10.18632/oncotarget.9814.

41.

Downregulation of long non-coding RNA MEG3 in nasopharyngeal carcinoma.

Chak WP, Lung RW, Tong JH, Chan SY, Lun SW, Tsao SW, Lo KW, To KF.

Mol Carcinog. 2017 Mar;56(3):1041-1054. doi: 10.1002/mc.22569. Epub 2016 Oct 20.

PMID:
27597634
42.

IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.

Fang X, Jeong JH, Long X, Park SJ, Wang D, Shuai M, Wei R, Li C, Li S, Zhang S, Duran MB, Lo KW, Tsao SW, Glaser R, Luo Z, Feng X, Tian Y, Luo JL.

Cell Death Differ. 2017 Jun;24(6):1133. doi: 10.1038/cdd.2016.106. Epub 2016 Sep 16.

43.

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs.

Chan JF, Yip CC, Tsang JO, Tee KM, Cai JP, Chik KK, Zhu Z, Chan CC, Choi GK, Sridhar S, Zhang AJ, Lu G, Chiu K, Lo AC, Tsao SW, Kok KH, Jin DY, Chan KH, Yuen KY.

Emerg Microbes Infect. 2016 Aug 24;5:e93. doi: 10.1038/emi.2016.99.

44.

Selective Targeting and Restrictive Damage for Nonspecific Cells by Pulsed Laser-Activated Hyaluronan-Gold Nanoparticles.

Rau LR, Tsao SW, Liaw JW, Tsai SW.

Biomacromolecules. 2016 Aug 8;17(8):2514-21. doi: 10.1021/acs.biomac.6b00386. Epub 2016 Jul 20.

PMID:
27439142
45.

Extremely stringent activation of p16INK4a prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression.

Hang S, Tiwari AF, Ngan HY, Yip YL, Cheung AL, Tsao SW, Deng W.

Oncotarget. 2016 Jul 19;7(29):45656-45670. doi: 10.18632/oncotarget.10120.

46.

IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma.

Tan HY, Wang N, Tsao SW, Che CM, Yuen MF, Feng Y.

Oncotarget. 2016 Jul 12;7(28):43792-43804. doi: 10.18632/oncotarget.9696.

47.

Neuropilin-2 promotes tumourigenicity and metastasis in oesophageal squamous cell carcinoma through ERK-MAPK-ETV4-MMP-E-cadherin deregulation.

Fung TM, Ng KY, Tong M, Chen JN, Chai S, Chan KT, Law S, Lee NP, Choi MY, Li B, Cheung AL, Tsao SW, Qin YR, Guan XY, Chan KW, Ma S.

J Pathol. 2016 Jul;239(3):309-19. doi: 10.1002/path.4728. Epub 2016 May 5.

PMID:
27063000
48.

IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.

Fang X, Jeong JH, Long X, Park SJ, Wang D, Shuai M, Wei R, Li C, Li S, Zhang S, Duran MB, Lo KW, Tsao SW, Glaser R, Luo Z, Feng X, Tian Y, Luo JL.

Cell Death Differ. 2016 Sep 1;23(9):1471-82. doi: 10.1038/cdd.2016.32. Epub 2016 Apr 8. Retraction in: Cell Death Differ. 2017 Jun;24(6):1133.

49.

Telomerase activity and its association with psychological stress, mental disorders, lifestyle factors and interventions: A systematic review.

Deng W, Cheung ST, Tsao SW, Wang XM, Tiwari AF.

Psychoneuroendocrinology. 2016 Feb;64:150-63. doi: 10.1016/j.psyneuen.2015.11.017. Epub 2015 Nov 25. Review.

PMID:
26677763
50.

Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects.

Hong M, Li S, Tan HY, Wang N, Tsao SW, Feng Y.

Int J Mol Sci. 2015 Dec 2;16(12):28705-45. doi: 10.3390/ijms161226126. Review.

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