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Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG.

Iyer S, Sam FS, DiPrimio N, Preston G, Verheijen J, Murthy K, Parton Z, Tsang H, Lao J, Morava E, Perlstein EO.

Dis Model Mech. 2019 Nov 11;12(11). pii: dmm040584. doi: 10.1242/dmm.040584.


Drug screens of NGLY1 deficiency in worm and fly models reveal catecholamine, NRF2 and anti-inflammatory-pathway activation as potential clinical approaches.

Iyer S, Mast JD, Tsang H, Rodriguez TP, DiPrimio N, Prangley M, Sam FS, Parton Z, Perlstein EO.

Dis Model Mech. 2019 Nov 4;12(11). pii: dmm040576. doi: 10.1242/dmm.040576.


The beneficial effects of Qigong on elderly depression.

Chan SHW, Tsang HWH.

Int Rev Neurobiol. 2019;147:155-188. doi: 10.1016/bs.irn.2019.06.004. Epub 2019 Jun 26.


Bibliometric study of research productivity in occupational therapy and physical therapy/physiotherapy in four Western countries and five Asian countries/regions.

Man DWK, Tsang WSF, Lu EY, Tsang HWH.

Aust Occup Ther J. 2019 Oct 9. doi: 10.1111/1440-1630.12608. [Epub ahead of print]


Treatment planning optimization with beam motion modeling for dynamic arc delivery of SBRT using Cyberknife with multileaf collimation.

Bedford JL, Tsang HS, Nill S, Oelfke U.

Med Phys. 2019 Oct 6. doi: 10.1002/mp.13848. [Epub ahead of print]


Non-invasive Potential Circulating mRNA Markers for Colorectal Adenoma Using Targeted Sequencing.

Xue VW, Cheung MT, Chan PT, Luk LLY, Lee VH, Au TC, Yu AC, Cho WCS, Tsang HFA, Chan AK, Wong SCC.

Sci Rep. 2019 Sep 10;9(1):12943. doi: 10.1038/s41598-019-49445-x.


ASDAS is associated with both the extent and intensity of DW-MRI spinal inflammation in active axial spondyloarthritis.

Chung HY, Chui ETF, Lee KH, Tsang HHL, Chan SCW, Lau CS.

RMD Open. 2019 Aug 6;5(2):e001008. doi: 10.1136/rmdopen-2019-001008. eCollection 2019.


Current and future molecular diagnostics of gastric cancer.

Choi RS, Lai WYX, Lee LTC, Wong WLC, Pei XM, Tsang HF, Leung JJ, Cho WCS, Chu MKM, Wong EYL, Wong SCC.

Expert Rev Mol Diagn. 2019 Oct;19(10):863-874. doi: 10.1080/14737159.2019.1660645. Epub 2019 Aug 29.


The applications of big data in molecular diagnostics.

Wong YKE, Lam KW, Ho KY, Yu CSA, Cho WC, Tsang HF, Chu MKM, Ng PWL, Tai CSW, Chan LWC, Wong EYL, Wong SCC.

Expert Rev Mol Diagn. 2019 Oct;19(10):905-917. doi: 10.1080/14737159.2019.1657834. Epub 2019 Aug 29.


The applications of metabolomics in the molecular diagnostics of cancer.

Cheung PK, Ma MH, Tse HF, Yeung KF, Tsang HF, Chu MKM, Kan CM, Cho WCS, Ng LBW, Chan LWC, Wong SCC.

Expert Rev Mol Diagn. 2019 Sep;19(9):785-793. doi: 10.1080/14737159.2019.1656530. Epub 2019 Aug 21.


Predictive biomarkers and tumor microenvironment in female genital melanomas: a multi-institutional study of 55 cases.

Yu Y, Tse KY, Lee HHY, Chow KL, Tsang HW, Wong RWC, Cheung ETY, Cheuk W, Lee VWK, Chan WK, Wong AST, Loong HHF, Chan KKL, Ngan HYS, Cheung ANY, Ip PPC.

Mod Pathol. 2019 Aug 5. doi: 10.1038/s41379-019-0345-2. [Epub ahead of print]


Dual-wavelength-band subwavelength grating coupler operating in the near infrared and extended shortwave infrared.

Zhou W, Tsang HK.

Opt Lett. 2019 Aug 1;44(15):3621-3624. doi: 10.1364/OL.44.003621.


Extracellular Histones Induced Eryptotic Death in Human Erythrocytes.

Yeung KW, Lau PM, Tsang HL, Ho HP, Kwan YW, Kong SK.

Cell Physiol Biochem. 2019;53(1):229-241. doi: 10.33594/000000132.


The Neuroscience of Nonpharmacological Traditional Chinese Therapy (NTCT) for Major Depressive Disorder: A Systematic Review and Meta-Analysis.

Ye J, Cheung WM, Tsang HWH.

Evid Based Complement Alternat Med. 2019 May 15;2019:2183403. doi: 10.1155/2019/2183403. eCollection 2019. Review.


The potential of circulating cell free RNA as a biomarker in cancer.

Cheung KWE, Choi SR, Lee LTC, Lee NLE, Tsang HF, Cheng YT, Cho WCS, Wong EYL, Wong SCC.

Expert Rev Mol Diagn. 2019 Jul;19(7):579-590. doi: 10.1080/14737159.2019.1633307. Epub 2019 Jun 24.


Psychometric properties and measurement invariance of the Weight Self-Stigma Questionnaire and Weight Bias Internalization Scale in children and adolescents.

Pakpour AH, Tsai MC, Lin YC, Strong C, Latner JD, Fung XCC, Lin CY, Tsang HWH.

Int J Clin Health Psychol. 2019 May;19(2):150-159. doi: 10.1016/j.ijchp.2019.03.001. Epub 2019 Apr 18.


Genetic testing to resolve the source of haemolytic antibody in solid organ transplantation.

Tsang HC, Samraj AN, Morse RJ, Krumm N, Hess JR, Pagano MB.

Blood Transfus. 2019 Jul;17(4):307-311. doi: 10.2450/2019.0054-19. Epub 2019 Jun 5.


An East Meets West Approach to the Understanding of Emotion Dysregulation in Depression: From Perspective to Scientific Evidence.

Ye J, Cai S, Cheung WM, Tsang HWH.

Front Psychol. 2019 Mar 28;10:574. doi: 10.3389/fpsyg.2019.00574. eCollection 2019. Review.


Clonal and Quantitative In Vivo Assessment of Hematopoietic Stem Cell Differentiation Reveals Strong Erythroid Potential of Multipotent Cells.

Boyer SW, Rajendiran S, Beaudin AE, Smith-Berdan S, Muthuswamy PK, Perez-Cunningham J, Martin EW, Cheung C, Tsang H, Landon M, Forsberg EC.

Stem Cell Reports. 2019 Apr 9;12(4):801-815. doi: 10.1016/j.stemcr.2019.02.007. Epub 2019 Mar 21.


Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells.

Lin YJ, Liang WM, Chen CJ, Tsang H, Chiou JS, Liu X, Cheng CF, Lin TH, Liao CC, Huang SM, Chen J, Tsai FJ, Li TM.

Phytomedicine. 2019 May;58:152893. doi: 10.1016/j.phymed.2019.152893. Epub 2019 Mar 13.


Lavender essential oil ameliorates depression-like behavior and increases neurogenesis and dendritic complexity in rats.

Sánchez-Vidaña DI, Po KK, Fung TK, Chow JK, Lau WK, So PK, Lau BW, Tsang HW.

Neurosci Lett. 2019 May 14;701:180-192. doi: 10.1016/j.neulet.2019.02.042. Epub 2019 Feb 28.


Psychometric validation of the EuroQoL 5-dimension (EQ-5D) questionnaire in patients with spondyloarthritis.

Tsang HHL, Cheung JPY, Wong CKH, Cheung PWH, Lau CS, Chung HY.

Arthritis Res Ther. 2019 Jan 30;21(1):41. doi: 10.1186/s13075-019-1826-x.


Effects of Chinese herbal medicine therapy on survival and hepatic outcomes in patients with hepatitis C virus infection in Taiwan.

Tsai FJ, Cheng CF, Chen CJ, Lin CY, Wu YF, Li TM, Chuang PH, Wu YC, Lai CH, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin JC, Lin CC, Liang WM, Lin YJ.

Phytomedicine. 2019 Apr;57:30-38. doi: 10.1016/j.phymed.2018.09.237. Epub 2018 Oct 3.


Enabling precision medicine via standard communication of HTS provenance, analysis, and results.

Alterovitz G, Dean D, Goble C, Crusoe MR, Soiland-Reyes S, Bell A, Hayes A, Suresh A, Purkayastha A, King CH, Taylor D, Johanson E, Thompson EE, Donaldson E, Morizono H, Tsang H, Vora JK, Goecks J, Yao J, Almeida JS, Keeney J, Addepalli K, Krampis K, Smith KM, Guo L, Walderhaug M, Schito M, Ezewudo M, Guimera N, Walsh P, Kahsay R, Gottipati S, Rodwell TC, Bloom T, Lai Y, Simonyan V, Mazumder R.

PLoS Biol. 2018 Dec 31;16(12):e3000099. doi: 10.1371/journal.pbio.3000099. eCollection 2018 Dec.


Efficient perfectly vertical grating coupler for multi-core fibers fabricated with 193  nm DUV lithography.

Tong Y, Zhou W, Tsang HK.

Opt Lett. 2018 Dec 1;43(23):5709-5712. doi: 10.1364/OL.43.005709.


A silicon nitride waveguide-integrated chemical vapor deposited graphene photodetector with 38 GHz bandwidth.

Gao Y, Tsang HK, Shu C.

Nanoscale. 2018 Nov 29;10(46):21851-21856. doi: 10.1039/c8nr03345e.


Erratum for Tsang et al., "Borneol Dehydrogenase from Pseudomonas sp. Strain TCU-HL1 Catalyzes the Oxidation of (+)-Borneol and Its Isomers to Camphor".

Tsang HL, Huang JL, Lin YH, Huang KF, Lu PL, Lin GH, Khine AA, Hu A, Chen HP.

Appl Environ Microbiol. 2018 Oct 30;84(22). pii: e02230-18. doi: 10.1128/AEM.02230-18. Print 2018 Nov 15. No abstract available.


Novel adaptive beam-dependent margins for additional OAR sparing.

Tsang HS, Kamerling CP, Ziegenhein P, Nill S, Oelfke U.

Phys Med Biol. 2018 Oct 29;63(21):215019. doi: 10.1088/1361-6560/aae658.


Performance evaluation of five commercial assays for detection of acetaminophen.

Chan BY, Tsang HM, Ng CW, Ling WH, Leung DC, Lee HH, Mak CM.

J Clin Lab Anal. 2019 Feb;33(2):e22683. doi: 10.1002/jcla.22683. Epub 2018 Oct 4.


Evaluation of Oral Antiretroviral Drugs in Mice With Metabolic and Neurologic Complications.

Tsai FJ, Ho MW, Lai CH, Chou CH, Li JP, Cheng CF, Wu YC, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Lin JC, Lin CC, Hsieh CL, Liang WM, Lin YJ.

Front Pharmacol. 2018 Sep 4;9:1004. doi: 10.3389/fphar.2018.01004. eCollection 2018.


Integrated germanium-on-silicon Franz-Keldysh vector modulator used with a Kramers-Kronig receiver.

Tong Y, Zhang Q, Wu X, Chow CW, Shu C, Tsang HK.

Opt Lett. 2018 Sep 15;43(18):4333-4336. doi: 10.1364/OL.43.004333.


Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter.

Burnett R, Chen H, Szyszkowicz M, Fann N, Hubbell B, Pope CA 3rd, Apte JS, Brauer M, Cohen A, Weichenthal S, Coggins J, Di Q, Brunekreef B, Frostad J, Lim SS, Kan H, Walker KD, Thurston GD, Hayes RB, Lim CC, Turner MC, Jerrett M, Krewski D, Gapstur SM, Diver WR, Ostro B, Goldberg D, Crouse DL, Martin RV, Peters P, Pinault L, Tjepkema M, van Donkelaar A, Villeneuve PJ, Miller AB, Yin P, Zhou M, Wang L, Janssen NAH, Marra M, Atkinson RW, Tsang H, Quoc Thach T, Cannon JB, Allen RT, Hart JE, Laden F, Cesaroni G, Forastiere F, Weinmayr G, Jaensch A, Nagel G, Concin H, Spadaro JV.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9592-9597. doi: 10.1073/pnas.1803222115. Epub 2018 Sep 4.


Diffusion-weighted imaging versus short tau inversion recovery sequence: Usefulness in detection of active sacroiliitis and early diagnosis of axial spondyloarthritis.

Chan CWS, Tsang HHL, Li PH, Lee KH, Lau CS, Wong PYS, Chung HY.

PLoS One. 2018 Aug 7;13(8):e0201040. doi: 10.1371/journal.pone.0201040. eCollection 2018.


Clinical Associations of Uveitis in Axial Spondyloarthritis Group and Ankylosing Spondylitis Group: Do They Represent the Same Disease?

Wong OM, Tsang HHL, Chan SCW, Lee KH, Li PH, Lau CS, Chung HY.

J Clin Rheumatol. 2018 Jul 20. doi: 10.1097/RHU.0000000000000869. [Epub ahead of print]


Rationale and design of the randomized multicentre His Optimized Pacing Evaluated for Heart Failure (HOPE-HF) trial.

Keene D, Arnold A, Shun-Shin MJ, Howard JP, Sohaib SA, Moore P, Tanner M, Quereshi N, Muthumala A, Chandresekeran B, Foley P, Leyva F, Adhya S, Falaschetti E, Tsang H, Vijayaraman P, Cleland JGF, Stegemann B, Francis DP, Whinnett ZI.

ESC Heart Fail. 2018 Oct;5(5):965-976. doi: 10.1002/ehf2.12315. Epub 2018 Jul 9. Review.


Psychometric evaluation of the Finnish translation of the assessment of communication and interaction skills (ACIS-FI).

Fan CW, Keponen R, Piikki S, Tsang HWH, Popova ES, Taylor R.

Scand J Occup Ther. 2018 Jun 28:1-10. doi: 10.1080/11038128.2018.1483425. [Epub ahead of print]


Menstrual Blood Human Papillomavirus DNA and TAP1 Gene Polymorphisms as Potential Biomarkers for Screening and Monitoring of Cervical Squamous Intraepithelial Lesion.

Wong SCC, Au TCC, Chan SCS, Ng LPW, Tsang HF.

J Infect Dis. 2018 Oct 20;218(11):1739-1745. doi: 10.1093/infdis/jiy369.


Anatomical variants of the paranasal sinuses in patients with mid-facial segment pain: Our experience of a cohort of twenty-three patients.

Mogre D, Banhegyi G, Tsang HK, Leong SC.

Clin Otolaryngol. 2018 Oct;43(5):1410-1414. doi: 10.1111/coa.13174. Epub 2018 Jul 2. No abstract available.


Tailorable dual-wavelength-band coupling in a transverse-electric-mode focusing subwavelength grating coupler.

Zhou W, Cheng Z, Sun X, Tsang HK.

Opt Lett. 2018 Jun 15;43(12):2985-2988. doi: 10.1364/OL.43.002985.


Mid-infrared high-Q germanium microring resonator.

Xiao TH, Zhao Z, Zhou W, Chang CY, Set SY, Takenaka M, Tsang HK, Cheng Z, Goda K.

Opt Lett. 2018 Jun 15;43(12):2885-2888. doi: 10.1364/OL.43.002885.


The Effect of Centrifugal Force in Quantification of Colorectal Cancer-Related mRNA in Plasma Using Targeted Sequencing.

Xue VW, Ng SSM, Leung WW, Ma BBY, Cho WCS, Au TCC, Yu ACS, Tsang HFA, Wong SCC.

Front Genet. 2018 May 15;9:165. doi: 10.3389/fgene.2018.00165. eCollection 2018.


Association between emergency admission for peptic ulcer bleeding and air pollution: a case-crossover analysis in Hong Kong's elderly population.

Tian L, Qiu H, Sun S, Tsang H, Chan KP, Leung WK.

Lancet Planet Health. 2017 May;1(2):e74-e81. doi: 10.1016/S2542-5196(17)30021-9. Epub 2017 May 5.


Streamlining a blood center and hospital transfusion service supply chain with an informatics vendor-managed inventory solution: development, implementation, and 3-month follow-up.

Tsang HC, Garcia A, Scott R, Lancaster D, Geary D, Nguyen AT, Shankar R, Buchanan L, Pham TD.

Transfusion. 2018 Jul;58(7):1718-1725. doi: 10.1111/trf.14766. Epub 2018 May 16.


Hotspot KRAS exon 2 mutations in CD166 positive colorectal cancer and colorectal adenoma cells.

Wong HL, Ng LPW, Koh SP, Chan LWC, Wong EYK, Xue VW, Tsang HFA, Chan AKC, Chiu KY, Cheuk W, Wong SCC.

Oncotarget. 2018 Apr 17;9(29):20426-20438. doi: 10.18632/oncotarget.24921. eCollection 2018 Apr 17.


Implementation and new insights in molecular diagnostics for HIV infection.

Tsang HF, Chan LW, Tong JC, Wong HT, Lai CK, Au TC, Chan AK, Ng LP, Cho WC, Wong SC.

Expert Rev Mol Diagn. 2018 May;18(5):433-441. doi: 10.1080/14737159.2018.1464393. Epub 2018 Apr 19. Review.


High-performance chemical vapor deposited graphene-on-silicon nitride waveguide photodetectors.

Gao Y, Zhou G, Zhao N, Tsang HK, Shu C.

Opt Lett. 2018 Mar 15;43(6):1399-1402. doi: 10.1364/OL.43.001399.


Effects of Chinese herbal medicine on hyperlipidemia and the risk of cardiovascular disease in HIV-infected patients in Taiwan.

Tsai FJ, Li TM, Cheng CF, Wu YC, Lai CH, Ho TJ, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin JC, Lin CC, Liang WM, Lin YJ.

J Ethnopharmacol. 2018 Jun 12;219:71-80. doi: 10.1016/j.jep.2018.03.006. Epub 2018 Mar 10.


C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation.

Lee CH, Zhang HH, Singh SP, Koo L, Kabat J, Tsang H, Singh TP, Farber JM.

Elife. 2018 Feb 22;7. pii: e32532. doi: 10.7554/eLife.32532.


Prognostic significance of Cytokeratin 20-positive lymph node vascular endothelial growth factor A mRNA and chromodomain helicase DNA binding protein 4 in pN0 colorectal cancer patients.

Wong SCC, Cheung MT, Luk LLY, Lee VHM, Chan PT, Tsang HFA, Wong EYK, Xue VW, Chan AKC, Chan JKC.

Oncotarget. 2017 Dec 19;9(6):6737-6751. doi: 10.18632/oncotarget.23424. eCollection 2018 Jan 23.


Pityriasis lichenoides-like drug reaction: A clinical histopathologic study of 10 cases.

Magro C, Guo R, Nguyen GH, Tsang H, Momtahen S.

Dermatol Online J. 2017 Nov 15;23(11). pii: 13030/qt7xd8j71z.

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