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C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.

Zhu J, Lee KY, Jong TT, Tsai NP.

J Neurochem. 2019 Jul 29. doi: 10.1111/jnc.14840. [Epub ahead of print]


The outcomes of statin therapy in patients with acute ischemic stroke in Taiwan: A nationwide epidemiologic study.

Lin HC, Lin JR, Tsai WC, Lu CH, Chang WN, Huang CC, Wang HC, Kung CT, Su CM, Su YJ, Lin WC, Cheng BC, Hsu CW, Lai YR, Tsai NW.

QJM. 2019 Jul 26. pii: hcz189. doi: 10.1093/qjmed/hcz189. [Epub ahead of print]


Adjunctive statin therapy reduces intracranial hemorrhage and 1-year mortality in patients with atrial fibrillation after acute ischemic stroke: A population-based epidemiological study from Taiwan.

Lin HC, Tsai WC, Lin JR, Chang WN, Huang CC, Wang HC, Kung CT, Su CM, Su YJ, Lin WC, Cheng BC, Lu CH, Tsai NW.

J Clin Neurosci. 2019 Jul 18. pii: S0967-5868(19)30879-3. doi: 10.1016/j.jocn.2019.07.045. [Epub ahead of print]


Changing demographics among populations prescribed HCV treatment, 2013-2017.

Tsai N, Bacon B, Curry M, Flamm SL, Milligan S, Wick N, Younossi Z, Afdhal N.

Am J Manag Care. 2019 Jul;25(7):319-323.


Juniperus communis Suppresses Melanoma Tumorigenesis by Inhibiting Tumor Growth and Inducing Apoptosis.

Gao HW, Huang XF, Yang TP, Chang KF, Yeh LW, Hsieh MC, Weng JC, Tsai NM.

Am J Chin Med. 2019;47(5):1171-1191. doi: 10.1142/S0192415X19500605. Epub 2019 Jul 17.


α-1-Acid Glycoprotein Concentration as an Outcome Predictor in Adult Patients with Sepsis.

Hsiao SY, Lai YR, Kung CT, Tsai NW, Su CM, Huang CC, Wang HC, Cheng BC, Su YJ, Lin WC, Chiang YF, Ko JY, Lu CH.

Biomed Res Int. 2019 Jun 12;2019:3174896. doi: 10.1155/2019/3174896. eCollection 2019.


The clinical characteristics of adult cryptococcal meningitis patients who died within one year of treatment with a focus on those with early mortality.

Tsai WC, Lien CY, Lee JJ, Huang CR, Tsai NW, Chang CC, Lu CH, Chang WN.

J Clin Neurosci. 2019 Sep;67:80-84. doi: 10.1016/j.jocn.2019.06.015. Epub 2019 Jun 18.


Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation.

Ng R, Manring H, Papoutsidakis N, Albertelli T, Tsai N, See CJ, Li X, Park J, Stevens TL, Bobbili PJ, Riaz M, Ren Y, Stoddard CE, Janssen PM, Bunch TJ, Hall SP, Lo YC, Jacoby DL, Qyang Y, Wright N, Ackermann MA, Campbell SG.

JCI Insight. 2019 Jun 13;5. pii: 128643. doi: 10.1172/jci.insight.128643.


A novel synthetic-genetic-array-based yeast one-hybrid system for high discovery rate and short processing time.

Yeh CS, Wang Z, Miao F, Ma H, Kao CT, Hsu TS, Yu JH, Hung ET, Lin CC, Kuan CY, Tsai NC, Zhou C, Qu GZ, Jiang J, Liu G, Wang JP, Li W, Chiang VL, Chang TH, Lin YJ.

Genome Res. 2019 Aug;29(8):1343-1351. doi: 10.1101/gr.245951.118. Epub 2019 Jun 11.


Long-term effects of surgical treatment on baroreflex function in patients with obstructive sleep apnea: an 18-month follow-up.

Huang CC, Lin HC, Lai YR, Tsai NW, Lin WC, Wang HC, Kung CT, Cheng BC, Su YJ, Su CM, Hsiao SY, Lu CH.

Sleep Med. 2019 Aug;60:152-158. doi: 10.1016/j.sleep.2019.03.017. Epub 2019 Apr 4.


Patient-reported outcomes in patients chronic viral hepatitis without cirrhosis: The impact of hepatitis B and C viral replication.

Younossi ZM, Stepanova M, Younossi I, Papatheodoridis G, Janssen HLA, Agarwal K, Nguyen MH, Gane E, Tsai N, Nader F.

Liver Int. 2019 Jun 7. doi: 10.1111/liv.14171. [Epub ahead of print]


The Effect of Stroke Subtypes on Baroreceptor Sensitivity, a Predict for Acute Stroke Outcome.

Tsai WC, Lin HC, Lai YR, Hsu CW, Huang CC, Wang HC, Su CM, Su YJ, Lin WC, Cheng BC, Chang WN, Lu CH, Tsai NW.

Biomed Res Int. 2019 Apr 18;2019:7614828. doi: 10.1155/2019/7614828. eCollection 2019.


HbA1C Variability Is Strongly Associated With the Severity of Cardiovascular Autonomic Neuropathy in Patients With Type 2 Diabetes After Longer Diabetes Duration.

Lai YR, Huang CC, Chiu WC, Liu RT, Tsai NW, Wang HC, Lin WC, Cheng BC, Su YJ, Su CM, Hsiao SY, Wang PW, Chen JF, Lu CH.

Front Neurosci. 2019 May 14;13:458. doi: 10.3389/fnins.2019.00458. eCollection 2019.


Regulation of axon growth by myosin II-dependent mechanocatalysis of cofilin activity.

Zhang XF, Ajeti V, Tsai N, Fereydooni A, Burns W, Murrell M, De La Cruz EM, Forscher P.

J Cell Biol. 2019 Jul 1;218(7):2329-2349. doi: 10.1083/jcb.201810054. Epub 2019 May 23.


Close relationship between cardiovagal function and sural sensory nerve action potential in type 2 diabetes.

Lai YR, Huang CC, Chiu WC, Liu RT, Tsai NW, Wang HC, Lin WC, Cheng BC, Su YJ, Su CM, Hsiao SY, Wang PW, Chen JF, Ko JY, Lu CH.

Clin Neurophysiol. 2019 Jul;130(7):1160-1165. doi: 10.1016/j.clinph.2019.03.036. Epub 2019 May 8.


Total Alanine Aminotransferase (ALT) Flares in Pregnant North American Women With Chronic Hepatitis B Infection: Results From a Prospective Observational Study.

Bzowej NH, Tran TT, Li R, Belle SH, Smith CI, Khalili M, Chung R, Tsai N, Terrault N; Hepatitis B Research Network (HBRN).

Am J Gastroenterol. 2019 Aug;114(8):1283-1291. doi: 10.14309/ajg.0000000000000221.


Predictive factors of neurologic deterioration in patients with spontaneous cerebellar hemorrhage: a retrospective analysis.

Ho YN, Hsu SY, Lin YT, Cheng FC, Lin YJ, Tsai NW, Lu CH, Wang HC.

BMC Neurol. 2019 May 1;19(1):81. doi: 10.1186/s12883-019-1312-8.


Diagnosis of Parapneumonia Pleural Effusion with Serum and Pleural Fluid Cell-Free DNA.

Su CM, Kung CT, Hsiao SY, Tsai NW, Lai YR, Huang CC, Wang HC, Lin WC, Cheng BC, Su YJ, Lu CH.

Biomed Res Int. 2019 Mar 4;2019:5028512. doi: 10.1155/2019/5028512. eCollection 2019.


The clinical characteristics and therapeutic outcomes of cryptococcal meningitis in elderly patients: a hospital-based study.

Tsai WC, Lien CY, Lee JJ, Hsiao WC, Huang CR, Tsai NW, Chang CC, Lu CH, Chang WN.

BMC Geriatr. 2019 Mar 25;19(1):91. doi: 10.1186/s12877-019-1108-0.


Lipo-PEG-PEI complex as an intracellular transporter for protein therapeutics.

Lin YL, Chen CH, Liu YK, Huang TH, Tsai NM, Tzou SC, Liao KW.

Int J Nanomedicine. 2019 Feb 13;14:1119-1130. doi: 10.2147/IJN.S188970. eCollection 2019.


Usability evaluation of an instructional application based on Google Glass for mobile phone disassembly tasks.

Wang CH, Tsai NH, Lu JM, Wang MJ.

Appl Ergon. 2019 May;77:58-69. doi: 10.1016/j.apergo.2019.01.007. Epub 2019 Jan 29.


Risk factors for the development of posttraumatic hydrocephalus after unilateral decompressive craniectomy in patients with traumatic brain injury.

Su TM, Lan CM, Lee TH, Hsu SW, Tsai NW, Lu CH.

J Clin Neurosci. 2019 May;63:62-67. doi: 10.1016/j.jocn.2019.02.006. Epub 2019 Mar 1.


HbA1C Variability Is Strongly Associated With the Severity of Peripheral Neuropathy in Patients With Type 2 Diabetes.

Lai YR, Chiu WC, Huang CC, Tsai NW, Wang HC, Lin WC, Cheng BC, Su YJ, Su CM, Hsiao SY, Lu CH.

Front Neurosci. 2019 Feb 13;13:90. doi: 10.3389/fnins.2019.00090. eCollection 2019.


Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies.

Lin YL, Tsai NM, Chen CH, Liu YK, Lee CJ, Chan YL, Wang YS, Chang YC, Lin CH, Huang TH, Wang CC, Chi KH, Liao KW.

J Nanobiotechnology. 2019 Feb 6;17(1):25. doi: 10.1186/s12951-019-0457-3.


Attitudes of visitors at adult intensive care unit toward organ donation and organ support.

Tsai NW, Leung YM, Ng PY, Liong T, Lee SF, Ngai CW, Sin WC, Koo J, Chan WM.

Chin Med J (Engl). 2019 Feb 5;132(3):373-376. doi: 10.1097/CM9.0000000000000059. No abstract available.


Antitumor Effect of n-Butylidenephthalide Encapsulated on B16/F10 Melanoma Cells In Vitro with a Polycationic Liposome Containing PEI and Polyethylene Glycol Complex.

Gao HW, Chang KF, Huang XF, Lin YL, Weng JC, Liao KW, Tsai NM.

Molecules. 2018 Dec 6;23(12). pii: E3224. doi: 10.3390/molecules23123224.


Entecavir and Peginterferon Alfa-2a in Adults With Hepatitis B e Antigen-Positive Immune-Tolerant Chronic Hepatitis B Virus Infection.

Feld JJ, Terrault NA, Lin HS, Belle SH, Chung RT, Tsai N, Khalili M, Perrillo R, Cooper SL, Ghany MG, Janssen HLA, Lok AS; Hepatitis B Research Network.

Hepatology. 2019 Jun;69(6):2338-2348. doi: 10.1002/hep.30417. Epub 2019 Mar 14.


Reduced lateral occipital gray matter volume is associated with physical frailty and cognitive impairment in Parkinson's disease.

Chen YS, Chen HL, Lu CH, Chen MH, Chou KH, Tsai NW, Yu CC, Chiang PL, Lin WC.

Eur Radiol. 2019 May;29(5):2659-2668. doi: 10.1007/s00330-018-5855-7. Epub 2018 Dec 6.


Outcomes of adjunctive steroid therapy in adult patients with bacterial meningitis in Taiwan: A nationwide population-based epidemiologic study.

Lai YR, Lin JR, Chang WN, Tsai NW, Huang CC, Wang HC, Su YJ, Lin WC, Cheng BC, Su CM, Hsiao SY, Kuo CE, Lu CH.

J Clin Neurosci. 2019 Mar;61:54-58. doi: 10.1016/j.jocn.2018.10.146. Epub 2018 Nov 19.


Manifestations and Outcomes of Patients with Parkinson's Disease and Serious Infection in the Emergency Department.

Su CM, Kung CT, Chen FC, Cheng HH, Hsiao SY, Lai YR, Huang CC, Tsai NW, Lu CH.

Biomed Res Int. 2018 Oct 17;2018:6014896. doi: 10.1155/2018/6014896. eCollection 2018.


Stress and executive control: Mechanisms, moderators, and malleability.

Tsai N, Eccles JS, Jaeggi SM.

Brain Cogn. 2019 Jul;133:54-59. doi: 10.1016/j.bandc.2018.10.004. Epub 2018 Nov 2.


Impact of Intra-Abdominal Adhesion on Dialysis Outcome in Peritoneal Dialysis Patients.

Cheng BC, Tsai NW, Lai YR, Huang CC, Lu CH.

Biomed Res Int. 2018 Sep 25;2018:1978765. doi: 10.1155/2018/1978765. eCollection 2018.


Antithrombin supplementation did not impact the incidence of pegylated asparaginase-induced venous thromboembolism in adults with acute lymphoblastic leukemia.

Chen J, Ngo D, Aldoss I, Shayani S, Tsai NC, Pullarkat V.

Leuk Lymphoma. 2019 May;60(5):1187-1192. doi: 10.1080/10428194.2018.1519811. Epub 2018 Oct 15.


Clinical Characteristics and Therapeutic Outcomes of Postneurosurgical Bacterial Meningitis in Elderly Patients over 65: A Hospital-based Study.

Lee JJ, Lien CY, Huang CR, Tsai NW, Chang CC, Lu CH, Chang WN.

Acta Neurol Taiwan. 2017 Dec 15;26(4):144-153.


Juniperus Communis Extract Exerts Antitumor Effects in Human Glioblastomas Through Blood-Brain Barrier.

Tsai, Tsai NM, Chang KF, Wang JC.

Cell Physiol Biochem. 2018;49(6):2443-2462. doi: 10.1159/000493842. Epub 2018 Sep 27.


Interaction of systemic oxidative stress and mesial temporal network degeneration in Parkinson's disease with and without cognitive impairment.

Chiang PL, Chen HL, Lu CH, Chen YS, Chou KH, Hsu TW, Chen MH, Tsai NW, Li SH, Lin WC.

J Neuroinflammation. 2018 Sep 26;15(1):281. doi: 10.1186/s12974-018-1317-z.


Increased circulating endothelial progenitor cells and improved short-term outcomes in acute non-cardioembolic stroke after hyperbaric oxygen therapy.

Chen CY, Wu RW, Tsai NW, Lee MS, Lin WC, Hsu MC, Huang CC, Lai YR, Kung CT, Wang HC, Su YJ, Su CM, Hsiao SY, Cheng BC, Chiang YF, Lu CH.

J Transl Med. 2018 Sep 12;16(1):255. doi: 10.1186/s12967-018-1629-x.


Ceftriaxone Treatment for Neuronal Deficits: A Histological and MEMRI Study in a Rat Model of Dementia with Lewy Bodies.

Ho YJ, Weng JC, Lin CL, Shen MS, Li HH, Liao WC, Tsai NM, Hung CS, Lai TJ, Lee IY.

Behav Neurol. 2018 Aug 1;2018:4618716. doi: 10.1155/2018/4618716. eCollection 2018.


Investigation of MicroRNA in Mitochondrial Apoptotic Pathway in Systemic Lupus Erythematosus.

Su YJ, Tsai NW, Kung CT, Wang HC, Lin WC, Huang CC, Chang YT, Su CM, Chiang YF, Cheng BC, Lin YJ, Lu CH.

Biomed Res Int. 2018 Jul 10;2018:9026357. doi: 10.1155/2018/9026357. eCollection 2018.


The prognostic factors of HIV-negative adult cryptococcal meningitis with a focus on cranial MRI-based neuroimaging findings.

Tsai WC, Lien CY, Lee JJ, Lin WC, Hsu CW, Huang CR, Tsai NW, Chang CC, Lu CH, Chang WN.

J Clin Neurosci. 2018 Sep;55:57-61. doi: 10.1016/j.jocn.2018.06.044. Epub 2018 Jul 2.


Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy.

Kim EC, Zhang J, Pang W, Wang S, Lee KY, Cavaretta JP, Walters J, Procko E, Tsai NP, Chung HJ.

Neurobiol Dis. 2018 Oct;118:76-93. doi: 10.1016/j.nbd.2018.07.004. Epub 2018 Jul 6.


Phase transitions in a programmable quantum spin glass simulator.

Harris R, Sato Y, Berkley AJ, Reis M, Altomare F, Amin MH, Boothby K, Bunyk P, Deng C, Enderud C, Huang S, Hoskinson E, Johnson MW, Ladizinsky E, Ladizinsky N, Lanting T, Li R, Medina T, Molavi R, Neufeld R, Oh T, Pavlov I, Perminov I, Poulin-Lamarre G, Rich C, Smirnov A, Swenson L, Tsai N, Volkmann M, Whittaker J, Yao J.

Science. 2018 Jul 13;361(6398):162-165. doi: 10.1126/science.aat2025.


Multi-center phase II trial of bortezomib and rituximab maintenance combination therapy in patients with mantle cell lymphoma after consolidative autologous stem cell transplantation.

Chen RW, Palmer JM, Tomassetti S, Popplewell LL, Alluin J, Chomchan P, Nademanee AP, Siddiqi T, Tsai NC, Chen L, Zuo F, Abary R, Cai JL, Herrera AF, Rossi JJ, Rosen ST, Forman SJ, Kwak LW, Holmberg LA.

J Hematol Oncol. 2018 Jun 28;11(1):87. doi: 10.1186/s13045-018-0631-3.


Therapy-related acute lymphoblastic leukemia has distinct clinical and cytogenetic features compared to de novo acute lymphoblastic leukemia, but outcomes are comparable in transplanted patients.

Aldoss I, Stiller T, Tsai NC, Song JY, Cao T, Bandara NA, Salhotra A, Khaled S, Aribi A, Al Malki MM, Mei M, Ali H, Spielberger R, O'Donnell M, Snyder D, Slavin T, Nakamura R, Stein AS, Forman SJ, Marcucci G, Pullarkat V.

Haematologica. 2018 Oct;103(10):1662-1668. doi: 10.3324/haematol.2018.193599. Epub 2018 Jun 14.


Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice.

Jewett KA, Lee KY, Eagleman DE, Soriano S, Tsai NP.

Neuropharmacology. 2018 Aug;138:182-192. doi: 10.1016/j.neuropharm.2018.06.011. Epub 2018 Jun 8.


Reduced gray matter volume and respiratory dysfunction in Parkinson's disease: a voxel-based morphometry study.

Lee SY, Chen MH, Chiang PL, Chen HL, Chou KH, Chen YC, Yu CC, Tsai NW, Li SH, Lu CH, Lin WC.

BMC Neurol. 2018 May 26;18(1):73. doi: 10.1186/s12883-018-1074-8.


Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2.

Lee KY, Jewett KA, Chung HJ, Tsai NP.

Hum Mol Genet. 2018 Aug 15;27(16):2805-2816. doi: 10.1093/hmg/ddy189.


Concentration and value of endocan on outcome in adult patients after severe sepsis.

Hsiao SY, Kung CT, Tsai NW, Su CM, Huang CC, Lai YR, Wang HC, Cheng BC, Su YJ, Lin WC, Chiang YF, Lu CH.

Clin Chim Acta. 2018 Aug;483:275-280. doi: 10.1016/j.cca.2018.05.007. Epub 2018 May 8.


Development of a computational promoter with highly efficient expression in tumors.

Ho SY, Chang BH, Chung CH, Lin YL, Chuang CH, Hsieh PJ, Huang WC, Tsai NM, Huang SC, Liu YK, Lo YC, Liao KW.

BMC Cancer. 2018 Apr 27;18(1):480. doi: 10.1186/s12885-018-4421-7.


Real-world use of elbasvir-grazoprevir in patients with chronic hepatitis C: retrospective analyses from the TRIO network.

Flamm SL, Bacon B, Curry MP, Milligan S, Nwankwo CU, Tsai N, Younossi Z, Afdhal N.

Aliment Pharmacol Ther. 2018 Jun;47(11):1511-1522. doi: 10.1111/apt.14635. Epub 2018 Apr 17.


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