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DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.

Lee KF, Tsai MM, Tsai CY, Huang CG, Ou YH, Hsieh CC, Hsieh HL, Wang CS, Lin KH.

Int J Mol Sci. 2019 Nov 13;20(22). pii: E5689. doi: 10.3390/ijms20225689.


Tumor progression-dependent angiogenesis in gastric cancer and its potential application.

Hsieh HL, Tsai MM.

World J Gastrointest Oncol. 2019 Sep 15;11(9):686-704. doi: 10.4251/wjgo.v11.i9.686. Review.


IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis.

Wang Q, Lepus CM, Raghu H, Reber LL, Tsai MM, Wong HH, von Kaeppler E, Lingampalli N, Bloom MS, Hu N, Elliott EE, Oliviero F, Punzi L, Giori NJ, Goodman SB, Chu CR, Sokolove J, Fukuoka Y, Schwartz LB, Galli SJ, Robinson WH.

Elife. 2019 May 14;8. pii: e39905. doi: 10.7554/eLife.39905.


Molecular functions and clinical impact of thyroid hormone-triggered autophagy in liver-related diseases.

Chi HC, Tsai CY, Tsai MM, Yeh CT, Lin KH.

J Biomed Sci. 2019 Mar 8;26(1):24. doi: 10.1186/s12929-019-0517-x. Review.


Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model.

Haslinger D, Waltes R, Yousaf A, Lindlar S, Schneider I, Lim CK, Tsai MM, Garvalov BK, Acker-Palmer A, Krezdorn N, Rotter B, Acker T, Guillemin GJ, Fulda S, Freitag CM, Chiocchetti AG.

Mol Autism. 2018 Nov 6;9:56. doi: 10.1186/s13229-018-0239-z. eCollection 2018.


Impact of DNA and RNA Methylation on Radiobiology and Cancer Progression.

Chi HC, Tsai CY, Tsai MM, Lin KH.

Int J Mol Sci. 2018 Feb 12;19(2). pii: E555. doi: 10.3390/ijms19020555. Review.


Argininosuccinate synthetase 1 contributes to gastric cancer invasion and progression by modulating autophagy.

Tsai CY, Chi HC, Chi LM, Yang HY, Tsai MM, Lee KF, Huang HW, Chou LF, Cheng AJ, Yang CW, Wang CS, Lin KH.

FASEB J. 2018 May;32(5):2601-2614. doi: 10.1096/fj.201700094R. Epub 2018 Jan 10. Erratum in: FASEB J. 2019 Jan;33(1):1522.


Roles of Long Noncoding RNAs in Recurrence and Metastasis of Radiotherapy-Resistant Cancer Stem Cells.

Chi HC, Tsai CY, Tsai MM, Yeh CT, Lin KH.

Int J Mol Sci. 2017 Sep 5;18(9). pii: E1903. doi: 10.3390/ijms18091903. Review.


Post-acute care for stroke - a retrospective cohort study in Taiwan.

Lai CL, Tsai MM, Luo JY, Liao WC, Hsu PS, Chen HY.

Patient Prefer Adherence. 2017 Aug 1;11:1309-1315. doi: 10.2147/PPA.S136041. eCollection 2017.


Thyroid hormone protects hepatocytes from HBx-induced carcinogenesis by enhancing mitochondrial turnover.

Chi HC, Chen SL, Lin SL, Tsai CY, Chuang WY, Lin YH, Huang YH, Tsai MM, Yeh CT, Lin KH.

Oncogene. 2017 Sep 14;36(37):5274-5284. doi: 10.1038/onc.2017.136. Epub 2017 May 15.


The long non-coding RNA LINC01013 enhances invasion of human anaplastic large-cell lymphoma.

Chung IH, Lu PH, Lin YH, Tsai MM, Lin YW, Yeh CT, Lin KH.

Sci Rep. 2017 Mar 22;7(1):295. doi: 10.1038/s41598-017-00382-7.


Corrigendum to "MicroRNA-196a/-196b promote cell metastasis via negative regulation of radixin in human gastric cancer" [Cancer Lett 351 (2014) 222-231].

Tsai MM, Wang CS, Tsai CY, Chen CY, Chi HC, Tseng YH, Chung PJ, Lin YH, Chung IH, Chen CY, Lin KH.

Cancer Lett. 2017 May 1;393:129. doi: 10.1016/j.canlet.2017.01.030. Epub 2017 Jan 28. No abstract available.


Thyroid hormone suppresses expression of stathmin and associated tumor growth in hepatocellular carcinoma.

Tseng YH, Huang YH, Lin TK, Wu SM, Chi HC, Tsai CY, Tsai MM, Lin YH, Chang WC, Chang YT, Chen WJ, Lin KH.

Sci Rep. 2016 Dec 9;6:38756. doi: 10.1038/srep38756.


MicroRNA-26b inhibits tumor metastasis by targeting the KPNA2/c-jun pathway in human gastric cancer.

Tsai MM, Huang HW, Wang CS, Lee KF, Tsai CY, Lu PH, Chi HC, Lin YH, Kuo LM, Lin KH.

Oncotarget. 2016 Jun 28;7(26):39511-39526. doi: 10.18632/oncotarget.8629.


Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy.

Chi HC, Chen SL, Tsai CY, Chuang WY, Huang YH, Tsai MM, Wu SM, Sun CP, Yeh CT, Lin KH.

Autophagy. 2016 Dec;12(12):2271-2285. Epub 2016 Sep 21.


[Exploring the Experience of Dysmenorrhea and Life Adjustments of Women Undergoing Traditional Chinese Medicine Treatment].

Tsai MM, Yang FC, Lee SM, Huang CM.

Hu Li Za Zhi. 2016 Aug;63(4):60-9. doi: 10.6224/JN.63.4.60. Chinese.


Chemotherapy resistance and metastasis-promoting effects of thyroid hormone in hepatocarcinoma cells are mediated by suppression of FoxO1 and Bim pathway.

Chi HC, Chen SL, Cheng YH, Lin TK, Tsai CY, Tsai MM, Lin YH, Huang YH, Lin KH.

Cell Death Dis. 2016 Aug 4;7(8):e2324. doi: 10.1038/cddis.2016.227.


Circulating microRNA-196a/b are novel biomarkers associated with metastatic gastric cancer.

Tsai MM, Wang CS, Tsai CY, Huang CG, Lee KF, Huang HW, Lin YH, Chi HC, Kuo LM, Lu PH, Lin KH.

Eur J Cancer. 2016 Sep;64:137-48. doi: 10.1016/j.ejca.2016.05.007. Epub 2016 Jul 12.


Potential Diagnostic, Prognostic and Therapeutic Targets of MicroRNAs in Human Gastric Cancer.

Tsai MM, Wang CS, Tsai CY, Huang HW, Chi HC, Lin YH, Lu PH, Lin KH.

Int J Mol Sci. 2016 Jun 16;17(6). pii: E945. doi: 10.3390/ijms17060945. Review.


Repression of microRNA-130b by thyroid hormone enhances cell motility.

Lin YH, Wu MH, Liao CJ, Huang YH, Chi HC, Wu SM, Chen CY, Tseng YH, Tsai CY, Chung IH, Tsai MM, Chen CY, Lin TP, Yeh YH, Chen WJ, Lin KH.

J Hepatol. 2015 Jun;62(6):1328-40. doi: 10.1016/j.jhep.2014.12.035. Epub 2015 Jan 21.


Co-targeting of multiple microRNAs on factor-Inhibiting hypoxia-Inducible factor gene for the pathogenesis of head and neck carcinomas.

Kao SY, Tsai MM, Wu CH, Chen JJ, Tseng SH, Lin SC, Chang KW.

Head Neck. 2016 Apr;38(4):522-8. doi: 10.1002/hed.23912. Epub 2015 Jun 16.


Potential prognostic, diagnostic and therapeutic markers for human gastric cancer.

Tsai MM, Wang CS, Tsai CY, Chi HC, Tseng YH, Lin KH.

World J Gastroenterol. 2014 Oct 14;20(38):13791-803. doi: 10.3748/wjg.v20.i38.13791. Review.


Thyroid hormone enhanced human hepatoma cell motility involves brain-specific serine protease 4 activation via ERK signaling.

Chen CY, Chung IH, Tsai MM, Tseng YH, Chi HC, Tsai CY, Lin YH, Wang YC, Chen CP, Wu TI, Yeh CT, Tai DI, Lin KH.

Mol Cancer. 2014 Jul 1;13:162. doi: 10.1186/1476-4598-13-162.


MicroRNA-196a/-196b promote cell metastasis via negative regulation of radixin in human gastric cancer.

Tsai MM, Wang CS, Tsai CY, Chen CY, Chi HC, Tseng YH, Chung PJ, Lin YH, Chung IH, Chen CY, Lin KH.

Cancer Lett. 2014 Sep 1;351(2):222-31. doi: 10.1016/j.canlet.2014.06.004. Epub 2014 Jun 13. Erratum in: Cancer Lett. 2017 May 1;393:129.


Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis.

Tsai CY, Wang CS, Tsai MM, Chi HC, Cheng WL, Tseng YH, Chen CY, Lin CD, Wu JI, Wang LH, Lin KH.

Clin Cancer Res. 2014 May 1;20(9):2276-88. doi: 10.1158/1078-0432.CCR-13-1221. Epub 2014 Mar 6.


Thyroid hormone receptor represses miR-17 expression to enhance tumor metastasis in human hepatoma cells.

Lin YH, Liao CJ, Huang YH, Wu MH, Chi HC, Wu SM, Chen CY, Tseng YH, Tsai CY, Chung IH, Wu TI, Tsai MM, Lin CD, Lin KH.

Oncogene. 2013 Sep 19;32(38):4509-18. doi: 10.1038/onc.2013.309. Epub 2013 Aug 5.


Molecular functions of thyroid hormones and their clinical significance in liver-related diseases.

Chi HC, Chen CY, Tsai MM, Tsai CY, Lin KH.

Biomed Res Int. 2013;2013:601361. doi: 10.1155/2013/601361. Epub 2013 Jun 26. Review.


Biological significance of a thyroid hormone-regulated secretome.

Chen CY, Tsai MM, Chi HC, Lin KH.

Biochim Biophys Acta. 2013 Nov;1834(11):2271-84. doi: 10.1016/j.bbapap.2013.02.016. Epub 2013 Feb 19. Review.


Epitope-specific mechanisms of IGF1R inhibition by ganitumab.

Calzone FJ, Cajulis E, Chung YA, Tsai MM, Mitchell P, Lu J, Chen C, Sun J, Radinsky R, Kendall R, Beltran PJ.

PLoS One. 2013;8(2):e55135. doi: 10.1371/journal.pone.0055135. Epub 2013 Feb 1.


Thyroid hormone suppresses cell proliferation through endoglin-mediated promotion of p21 stability.

Lin YH, Huang YH, Wu MH, Wu SM, Chi HC, Liao CJ, Chen CY, Tseng YH, Tsai CY, Tsai MM, Lin KH.

Oncogene. 2013 Aug 15;32(33):3904-14. doi: 10.1038/onc.2013.5. Epub 2013 Feb 4.


miR-196a overexpression and miR-196a2 gene polymorphism are prognostic predictors of oral carcinomas.

Liu CJ, Tsai MM, Tu HF, Lui MT, Cheng HW, Lin SC.

Ann Surg Oncol. 2013 Dec;20 Suppl 3:S406-14. doi: 10.1245/s10434-012-2618-6. Epub 2012 Nov 9.


Passenger strand miRNA miR-31* regulates the phenotypes of oral cancer cells by targeting RhoA.

Chang KW, Kao SY, Wu YH, Tsai MM, Tu HF, Liu CJ, Lui MT, Lin SC.

Oral Oncol. 2013 Jan;49(1):27-33. doi: 10.1016/j.oraloncology.2012.07.003. Epub 2012 Jul 31.


FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality.

Shalhoub V, Shatzen EM, Ward SC, Davis J, Stevens J, Bi V, Renshaw L, Hawkins N, Wang W, Chen C, Tsai MM, Cattley RC, Wronski TJ, Xia X, Li X, Henley C, Eschenberg M, Richards WG.

J Clin Invest. 2012 Jul;122(7):2543-53. doi: 10.1172/JCI61405. Epub 2012 Jun 25.


Thyroid hormone receptors promote metastasis of human hepatoma cells via regulation of TRAIL.

Chi HC, Chen SL, Liao CJ, Liao CH, Tsai MM, Lin YH, Huang YH, Yeh CT, Wu SM, Tseng YH, Chen CY, Tsai CY, Chung IH, Chen WJ, Lin KH.

Cell Death Differ. 2012 Nov;19(11):1802-14. doi: 10.1038/cdd.2012.58. Epub 2012 May 11.


Glyoxalase-I is a novel prognosis factor associated with gastric cancer progression.

Cheng WL, Tsai MM, Tsai CY, Huang YH, Chen CY, Chi HC, Tseng YH, Chao IW, Lin WC, Wu SM, Liang Y, Liao CJ, Lin YH, Chung IH, Chen WJ, Lin PY, Wang CS, Lin KH.

PLoS One. 2012;7(3):e34352. doi: 10.1371/journal.pone.0034352. Epub 2012 Mar 29.


Overexpression of ADP-ribosylation factor 1 in human gastric carcinoma and its clinicopathological significance.

Tsai MM, Lin PY, Cheng WL, Tsai CY, Chi HC, Chen CY, Tseng YH, Cheng YF, Chen CD, Liang Y, Liao CJ, Wu SM, Lin YH, Chung IH, Wang CS, Lin KH.

Cancer Sci. 2012 Jun;103(6):1136-44. doi: 10.1111/j.1349-7006.2012.02243.x. Epub 2012 Mar 28. Erratum in: Cancer Sci. 2017 Feb;108(2):277-278.


Stable isotope labeling with amino acids in cell culture (SILAC)-based quantitative proteomics study of a thyroid hormone-regulated secretome in human hepatoma cells.

Chen CY, Chi LM, Chi HC, Tsai MM, Tsai CY, Tseng YH, Lin YH, Chen WJ, Huang YH, Lin KH.

Mol Cell Proteomics. 2012 Apr;11(4):M111.011270. doi: 10.1074/mcp.M111.011270. Epub 2011 Dec 14.


Dickkopf 4 positively regulated by the thyroid hormone receptor suppresses cell invasion in human hepatoma cells.

Liao CH, Yeh CT, Huang YH, Wu SM, Chi HC, Tsai MM, Tsai CY, Liao CJ, Tseng YH, Lin YH, Chen CY, Chung IH, Cheng WL, Chen WJ, Lin KH.

Hepatology. 2012 Mar;55(3):910-20. doi: 10.1002/hep.24740. Epub 2012 Jan 13.


Glucose-regulated protein 58 modulates cell invasiveness and serves as a prognostic marker for cervical cancer.

Liao CJ, Wu TI, Huang YH, Chang TC, Wang CS, Tsai MM, Lai CH, Liang Y, Jung SM, Lin KH.

Cancer Sci. 2011 Dec;102(12):2255-63. doi: 10.1111/j.1349-7006.2011.02102.x. Epub 2011 Oct 17.


Overexpression of CXCL1 and its receptor CXCR2 promote tumor invasion in gastric cancer.

Cheng WL, Wang CS, Huang YH, Tsai MM, Liang Y, Lin KH.

Ann Oncol. 2011 Oct;22(10):2267-76. doi: 10.1093/annonc/mdq739. Epub 2011 Feb 22. Erratum in: Ann Oncol. 2011 Nov;22(11):2537.


miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells.

Yang CJ, Shen WG, Liu CJ, Chen YW, Lu HH, Tsai MM, Lin SC.

J Oral Pathol Med. 2011 Aug;40(7):560-6. doi: 10.1111/j.1600-0714.2010.01005.x. Epub 2011 Jan 13.


Cathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cells.

Wu SM, Huang YH, Yeh CT, Tsai MM, Liao CH, Cheng WL, Chen WJ, Lin KH.

Oncogene. 2011 Apr 28;30(17):2057-69. doi: 10.1038/onc.2010.585. Epub 2011 Jan 10.


Overexpression of gelsolin in human cervical carcinoma and its clinicopathological significance.

Liao CJ, Wu TI, Huang YH, Chang TC, Wang CS, Tsai MM, Hsu CY, Tsai MH, Lai CH, Lin KH.

Gynecol Oncol. 2011 Jan;120(1):135-44. doi: 10.1016/j.ygyno.2010.10.005. Epub 2010 Oct 28.


Increase of microRNA miR-31 level in plasma could be a potential marker of oral cancer.

Liu CJ, Kao SY, Tu HF, Tsai MM, Chang KW, Lin SC.

Oral Dis. 2010 May;16(4):360-4. doi: 10.1111/j.1601-0825.2009.01646.x. Epub 2010 Mar 9.


Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines.

Wu SM, Huang YH, Lu YH, Chien LF, Yeh CT, Tsai MM, Liao CH, Chen WJ, Liao CJ, Cheng WL, Lin KH.

Cell Mol Life Sci. 2010 Jun;67(11):1831-43. doi: 10.1007/s00018-010-0281-2. Epub 2010 Feb 10.


miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma.

Liu CJ, Tsai MM, Hung PS, Kao SY, Liu TY, Wu KJ, Chiou SH, Lin SC, Chang KW.

Cancer Res. 2010 Feb 15;70(4):1635-44. doi: 10.1158/0008-5472.CAN-09-2291. Epub 2010 Feb 9.


Morphological changes of short-wavelength cones in the developing S334ter-3 transgenic rat.

Hombrebueno JR, Tsai MM, Kim HL, De Juan J, Grzywacz NM, Lee EJ.

Brain Res. 2010 Mar 19;1321:60-6. doi: 10.1016/j.brainres.2010.01.051. Epub 2010 Jan 28.


Positive regulation of spondin 2 by thyroid hormone is associated with cell migration and invasion.

Liao CH, Yeh SC, Huang YH, Chen RN, Tsai MM, Chen WJ, Chi HC, Tai PJ, Liao CJ, Wu SM, Cheng WL, Pai LM, Lin KH.

Endocr Relat Cancer. 2010 Jan 29;17(1):99-111. doi: 10.1677/ERC-09-0050. Print 2010 Mar.


A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.

Chan JC, Piper DE, Cao Q, Liu D, King C, Wang W, Tang J, Liu Q, Higbee J, Xia Z, Di Y, Shetterly S, Arimura Z, Salomonis H, Romanow WG, Thibault ST, Zhang R, Cao P, Yang XP, Yu T, Lu M, Retter MW, Kwon G, Henne K, Pan O, Tsai MM, Fuchslocher B, Yang E, Zhou L, Lee KJ, Daris M, Sheng J, Wang Y, Shen WD, Yeh WC, Emery M, Walker NP, Shan B, Schwarz M, Jackson SM.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9820-5. doi: 10.1073/pnas.0903849106. Epub 2009 May 14.

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