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Items: 1 to 50 of 302

1.

3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.

Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH.

Commun Biol. 2019 Oct 4;2(1):360. doi: 10.1038/s42003-019-0599-8.

PMID:
31925184
2.

Risk factors for restless legs syndrome in hemodialysis patients in Taiwan: A case-control study.

Tsai LH, See LC, Chien CC, Chen CM, Chang SH.

Medicine (Baltimore). 2019 Dec;98(51):e18450. doi: 10.1097/MD.0000000000018450.

3.

Gamma Entrainment: Impact on Neurocircuits, Glia, and Therapeutic Opportunities.

Adaikkan C, Tsai LH.

Trends Neurosci. 2020 Jan;43(1):24-41. doi: 10.1016/j.tins.2019.11.001. Epub 2019 Dec 10. Review.

PMID:
31836315
4.

Relationship between refractive correction, visual symptoms, and optical device selection for low-vision patients in Taiwan.

Tsai LH, Hsieh HP, Chen PS, Jou CL, Tseng KY, Cheng CY.

J Optom. 2019 Nov 29. pii: S1888-4296(19)30090-1. doi: 10.1016/j.optom.2019.09.003. [Epub ahead of print]

5.

Adaptation of Diagnosis from Autism Spectrum Disorder to Social Communication Disorder in Adolescents with ADHD.

Tsai LH, Lin JW.

J Autism Dev Disord. 2019 Oct 24. doi: 10.1007/s10803-019-04265-w. [Epub ahead of print]

PMID:
31650372
6.

3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.

Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH.

Commun Biol. 2019 Oct 4;2:360. doi: 10.1038/s42003-019-0599-8. eCollection 2019.

7.

Use of clozapine for resolving lamotrigine-induced skin lesions caused by schizophrenia treatment.

Tsai LH, Lin JW.

Psychiatr Danub. 2019 Sep;31(3):362-365. doi: 10.24869/psyd.2019.362. No abstract available.

8.

Internal hernia from the interureteric space after robot-assisted radical cystectomy and urinary diversion: Two case reports.

Tsai LH, Li WJ, Chen GH, Hsieh PF, Chang CH.

Medicine (Baltimore). 2019 Oct;98(41):e17222. doi: 10.1097/MD.0000000000017222.

9.

Impact of the caller's emotional state and cooperation on out-of-hospital cardiac arrest recognition and dispatcher-assisted cardiopulmonary resuscitation.

Chien CY, Chien WC, Tsai LH, Tsai SL, Chen CB, Seak CJ, Chou YS, Ma M, Weng YM, Ng CJ, Lin CY, Tzeng IS, Lin CC, Huang CH.

Emerg Med J. 2019 Oct;36(10):595-600. doi: 10.1136/emermed-2018-208353. Epub 2019 Aug 22.

PMID:
31439715
10.

Modeling Alzheimer's disease with iPSC-derived brain cells.

Penney J, Ralvenius WT, Tsai LH.

Mol Psychiatry. 2020 Jan;25(1):148-167. doi: 10.1038/s41380-019-0468-3. Epub 2019 Aug 7. Review.

11.

Author Correction: Single-cell transcriptomic analysis of Alzheimer's disease.

Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH.

Nature. 2019 Jul;571(7763):E1. doi: 10.1038/s41586-019-1329-6.

PMID:
31209304
12.

The intracellular domain of CX3CL1 regulates adult neurogenesis and Alzheimer's amyloid pathology.

Fan Q, Gayen M, Singh N, Gao F, He W, Hu X, Tsai LH, Yan R.

J Exp Med. 2019 Aug 5;216(8):1891-1903. doi: 10.1084/jem.20182238. Epub 2019 Jun 17.

PMID:
31209068
13.

Examining the Role of HDACs in DNA Double-Strand Break Repair in Neurons.

Pao PC, Penney J, Tsai LH.

Methods Mol Biol. 2019;1983:225-234. doi: 10.1007/978-1-4939-9434-2_13.

PMID:
31087301
14.

Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection.

Adaikkan C, Middleton SJ, Marco A, Pao PC, Mathys H, Kim DN, Gao F, Young JZ, Suk HJ, Boyden ES, McHugh TJ, Tsai LH.

Neuron. 2019 Jun 5;102(5):929-943.e8. doi: 10.1016/j.neuron.2019.04.011. Epub 2019 May 7.

PMID:
31076275
15.

Single-cell transcriptomic analysis of Alzheimer's disease.

Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH.

Nature. 2019 Jun;570(7761):332-337. doi: 10.1038/s41586-019-1195-2. Epub 2019 May 1. Erratum in: Nature. 2019 Jun 17;:.

16.

Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition.

Martorell AJ, Paulson AL, Suk HJ, Abdurrob F, Drummond GT, Guan W, Young JZ, Kim DN, Kritskiy O, Barker SJ, Mangena V, Prince SM, Brown EN, Chung K, Boyden ES, Singer AC, Tsai LH.

Cell. 2019 Apr 4;177(2):256-271.e22. doi: 10.1016/j.cell.2019.02.014. Epub 2019 Mar 14.

PMID:
30879788
17.

The complexity of neuroinflammation at single-cell resolution.

Raju RM, Tsai LH.

Nat Rev Neurol. 2019 May;15(5):249-250. doi: 10.1038/s41582-019-0165-5. No abstract available.

PMID:
30858531
18.

Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer's Disease.

Blanchard JW, Tsai LH.

Cell Stem Cell. 2019 Mar 7;24(3):347-349. doi: 10.1016/j.stem.2019.02.003.

PMID:
30849361
19.

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease.

Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA.

Cell Rep. 2019 Jan 29;26(5):1112-1127.e9. doi: 10.1016/j.celrep.2019.01.023.

20.

S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy.

Amal H, Gong G, Gjoneska E, Lewis SM, Wishnok JS, Tsai LH, Tannenbaum SR.

Transl Psychiatry. 2019 Jan 29;9(1):44. doi: 10.1038/s41398-019-0388-7.

21.

Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.

Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL.

Nat Neurosci. 2019 Jan;22(1):37-46. doi: 10.1038/s41593-018-0291-1. Epub 2018 Dec 17.

22.

Elimination of senescent cells prevents neurodegeneration in mice.

Penney J, Tsai LH.

Nature. 2018 Oct;562(7728):503-504. doi: 10.1038/d41586-018-06677-7. No abstract available.

PMID:
30349121
23.
24.

Noninvasive 40-Hz light flicker to recruit microglia and reduce amyloid beta load.

Singer AC, Martorell AJ, Douglas JM, Abdurrob F, Attokaren MK, Tipton J, Mathys H, Adaikkan C, Tsai LH.

Nat Protoc. 2018 Aug;13(8):1850-1868. doi: 10.1038/s41596-018-0021-x.

PMID:
30072722
25.

Author Correction: Gamma frequency entrainment attenuates amyloid load and modifies microglia.

Iaccarino HF, Singer AC, Martorell AJ, Rudenko A, Gao F, Gillingham TZ, Mathys H, Seo J, Kritskiy O, Abdurrob F, Adaikkan C, Canter RG, Rueda R, Brown EN, Boyden ES, Tsai LH.

Nature. 2018 Oct;562(7725):E1. doi: 10.1038/s41586-018-0351-4.

PMID:
30046102
26.

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.

Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH.

Neuron. 2018 Jun 27;98(6):1294. doi: 10.1016/j.neuron.2018.06.011. No abstract available.

27.

Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory.

Zhao WN, Ghosh B, Tyler M, Lalonde J, Joseph NF, Kosaric N, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ.

ACS Chem Neurosci. 2018 Sep 19;9(9):2262-2273. doi: 10.1021/acschemneuro.8b00116. Epub 2018 Jun 22.

PMID:
29932631
28.

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.

Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH.

Neuron. 2018 Jun 27;98(6):1141-1154.e7. doi: 10.1016/j.neuron.2018.05.008. Epub 2018 May 31. Erratum in: Neuron. 2018 Jun 27;98 (6):1294.

29.

A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations.

Litichevskiy L, Peckner R, Abelin JG, Asiedu JK, Creech AL, Davis JF, Davison D, Dunning CM, Egertson JD, Egri S, Gould J, Ko T, Johnson SA, Lahr DL, Lam D, Liu Z, Lyons NJ, Lu X, MacLean BX, Mungenast AE, Officer A, Natoli TE, Papanastasiou M, Patel J, Sharma V, Toder C, Tubelli AA, Young JZ, Carr SA, Golub TR, Subramanian A, MacCoss MJ, Tsai LH, Jaffe JD.

Cell Syst. 2018 Apr 25;6(4):424-443.e7. doi: 10.1016/j.cels.2018.03.012. Epub 2018 Apr 11.

30.

Association between acidosis and outcome in out-of-hospital cardiac arrest patients.

Lin CC, Lin CY, Huang CH, Tsai LH, Kuo CW, Chien CY.

Am J Emerg Med. 2018 Dec;36(12):2309-2310. doi: 10.1016/j.ajem.2018.04.002. Epub 2018 Apr 3. No abstract available.

PMID:
29650396
31.

A Developmental Switch in Microglial HDAC Function.

Mathys H, Penney J, Tsai LH.

Immunity. 2018 Mar 20;48(3):476-478. doi: 10.1016/j.immuni.2018.03.010.

32.

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution.

Mathys H, Adaikkan C, Gao F, Young JZ, Manet E, Hemberg M, De Jager PL, Ransohoff RM, Regev A, Tsai LH.

Cell Rep. 2017 Oct 10;21(2):366-380. doi: 10.1016/j.celrep.2017.09.039.

33.

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.

Seo J, Kritskiy O, Watson LA, Barker SJ, Dey D, Raja WK, Lin YT, Ko T, Cho S, Penney J, Silva MC, Sheridan SD, Lucente D, Gusella JF, Dickerson BC, Haggarty SJ, Tsai LH.

J Neurosci. 2017 Oct 11;37(41):9917-9924. doi: 10.1523/JNEUROSCI.0621-17.2017. Epub 2017 Sep 14.

34.

Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects.

Penney J, Seo J, Kritskiy O, Elmsaouri S, Gao F, Pao PC, Su SC, Tsai LH.

J Neurosci. 2017 Sep 6;37(36):8655-8666. doi: 10.1523/JNEUROSCI.0591-17.2017. Epub 2017 Aug 3.

35.

The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons.

Yamakawa H, Cheng J, Penney J, Gao F, Rueda R, Wang J, Yamakawa S, Kritskiy O, Gjoneska E, Tsai LH.

Cell Rep. 2017 Aug 8;20(6):1319-1334. doi: 10.1016/j.celrep.2017.07.044.

36.

Comparison of prehospital triage and five-level triage system at the emergency department.

Tsai LH, Huang CH, Su YC, Weng YM, Chaou CH, Li WC, Kuo CW, Ng CJ.

Emerg Med J. 2017 Nov;34(11):720-725. doi: 10.1136/emermed-2015-205304. Epub 2017 Jul 18.

PMID:
28720720
37.

Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields.

Grossman N, Bono D, Dedic N, Kodandaramaiah SB, Rudenko A, Suk HJ, Cassara AM, Neufeld E, Kuster N, Tsai LH, Pascual-Leone A, Boyden ES.

Cell. 2017 Jun 1;169(6):1029-1041.e16. doi: 10.1016/j.cell.2017.05.024.

38.

Molecular biology: Local metabolites linked to memory.

Watson LA, Tsai LH.

Nature. 2017 Jun 15;546(7658):361-362. doi: 10.1038/nature22498. Epub 2017 May 31. No abstract available.

PMID:
28562586
39.

MethyLock: DNA Demethylation Is the Epigenetic Key to Axon Regeneration.

Barker SJ, Tsai LH.

Neuron. 2017 Apr 19;94(2):221-223. doi: 10.1016/j.neuron.2017.04.006. Review.

40.

TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice.

Shukla V, Seo J, Binukumar BK, Amin ND, Reddy P, Grant P, Kuntz S, Kesavapany S, Steiner J, Mishra SK, Tsai LH, Pant HC.

J Alzheimers Dis. 2017;56(1):335-349. doi: 10.3233/JAD-160916.

PMID:
28085018
41.

In the loop: how chromatin topology links genome structure to function in mechanisms underlying learning and memory.

Watson LA, Tsai LH.

Curr Opin Neurobiol. 2017 Apr;43:48-55. doi: 10.1016/j.conb.2016.12.002. Epub 2016 Dec 23. Review.

42.

A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory.

Mathew RS, Tatarakis A, Rudenko A, Johnson-Venkatesh EM, Yang YJ, Murphy EA, Todd TP, Schepers ST, Siuti N, Martorell AJ, Falls WA, Hammack SE, Walsh CA, Tsai LH, Umemori H, Bouton ME, Moazed D.

Elife. 2016 Dec 21;5. pii: e22467. doi: 10.7554/eLife.22467.

43.

Gamma frequency entrainment attenuates amyloid load and modifies microglia.

Iaccarino HF, Singer AC, Martorell AJ, Rudenko A, Gao F, Gillingham TZ, Mathys H, Seo J, Kritskiy O, Abdurrob F, Adaikkan C, Canter RG, Rueda R, Brown EN, Boyden ES, Tsai LH.

Nature. 2016 Dec 7;540(7632):230-235. doi: 10.1038/nature20587. Erratum in: Nature. 2018 Oct;562(7725):E1.

44.

The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System.

Cholewa-Waclaw J, Bird A, von Schimmelmann M, Schaefer A, Yu H, Song H, Madabhushi R, Tsai LH.

J Neurosci. 2016 Nov 9;36(45):11427-11434. Review.

45.

The road to restoring neural circuits for the treatment of Alzheimer's disease.

Canter RG, Penney J, Tsai LH.

Nature. 2016 Nov 10;539(7628):187-196. doi: 10.1038/nature20412. Review.

PMID:
27830780
46.

Efficient derivation of microglia-like cells from human pluripotent stem cells.

Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, Bakiasi G, Tsai LH, Aubourg P, Ransohoff RM, Jaenisch R.

Nat Med. 2016 Nov;22(11):1358-1367. doi: 10.1038/nm.4189. Epub 2016 Sep 26.

47.

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling.

Durak O, Gao F, Kaeser-Woo YJ, Rueda R, Martorell AJ, Nott A, Liu CY, Watson LA, Tsai LH.

Nat Neurosci. 2016 Nov;19(11):1477-1488. doi: 10.1038/nn.4400. Epub 2016 Oct 3.

48.

Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.

Nott A, Cheng J, Gao F, Lin YT, Gjoneska E, Ko T, Minhas P, Zamudio AV, Meng J, Zhang F, Jin P, Tsai LH.

Nat Neurosci. 2016 Nov;19(11):1497-1505. doi: 10.1038/nn.4347. Epub 2016 Jul 18.

49.

Transient enhancement of proliferation of neural progenitors and impairment of their long-term survival in p25 transgenic mice.

Zou D, Zhou Y, Liu L, Dong F, Shu T, Zhou Y, Tsai LH, Mao Y.

Oncotarget. 2016 Jun 28;7(26):39148-39161. doi: 10.18632/oncotarget.9834.

50.

Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.

Raja WK, Mungenast AE, Lin YT, Ko T, Abdurrob F, Seo J, Tsai LH.

PLoS One. 2016 Sep 13;11(9):e0161969. doi: 10.1371/journal.pone.0161969. eCollection 2016.

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