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Adjuvant radiotherapy after curative surgery for oral cavity squamous cell carcinoma and treatment effect of timing and duration on outcome-A Taiwan Cancer Registry national database analysis.

Cheng YJ, Tsai MH, Chiang CJ, Tsai ST, Liu TW, Lou PJ, Liao CT, Lin JC, Chang JT, Tsai MH, Chu PY, Leu YS, Tsai KY, Terng SD, Chien CY, Yang MH, Hao SP, Wang CC, Tsai MH, Chen HHW, Kuo C, Wu YH.

Cancer Med. 2018 Jun 14. doi: 10.1002/cam4.1611. [Epub ahead of print]


Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication.

Tsai K, Courtney DG, Kennedy EM, Cullen BR.

RNA. 2018 Jun 14. pii: rna.066332.118. doi: 10.1261/rna.066332.118. [Epub ahead of print]


Helicobacter pylori eradication with bismuth quadruple therapy leads to dysbiosis of gut microbiota with an increased relative abundance of Proteobacteria and decreased relative abundances of Bacteroidetes and Actinobacteria.

Hsu PI, Pan CY, Kao JY, Tsay FW, Peng NJ, Kao SS, Wang HM, Tsai TJ, Wu DC, Chen CL, Tsai KW; Taiwan Acid-related Disease (TARD) Study Group.

Helicobacter. 2018 Jun 13:e12498. doi: 10.1111/hel.12498. [Epub ahead of print]


Association between proton pump inhibitors and the risk of hepatocellular carcinoma.

Shao YJ, Chan TS, Tsai K, Wu SY.

Aliment Pharmacol Ther. 2018 Jun 13. doi: 10.1111/apt.14835. [Epub ahead of print]


Diverse populations of local interneurons integrate into the Drosophila adult olfactory circuit.

Liou NF, Lin SH, Chen YJ, Tsai KT, Yang CJ, Lin TY, Wu TH, Lin HJ, Chen YT, Gohl DM, Silies M, Chou YH.

Nat Commun. 2018 Jun 8;9(1):2232. doi: 10.1038/s41467-018-04675-x.


First-in-human brain imaging of Alzheimer dementia patients and elderly controls with 18F-MK-6240, a PET tracer targeting neurofibrillary tangle pathology.

Lohith TG, Bennacef I, Vandenberghe R, Vandenbulcke M, Salinas-Valenzuela C, Declercq R, Reynders T, Telan-Choing F, Riffel K, Celen S, Serdons K, Bormans G, Tsai K, Walji A, Hostetler ED, Evelhoch JL, Van Laere K, Forman M, Stoch A, Sur C, Struyk A.

J Nucl Med. 2018 Jun 7. pii: jnumed.118.208215. doi: 10.2967/jnumed.118.208215. [Epub ahead of print]


Protein-DNA complex-guided discovery of the antibacterial lead E1 for restoring the susceptibility of Klebsiella Pneumoniae to polymyxin B by targeting the response regulator PmrA.

Tseng TS, Tu IF, Chen HT, Lin LC, Tsai KC, Wu SH, Chen C.

Chem Commun (Camb). 2018 Jun 14;54(49):6372-6375. doi: 10.1039/c8cc01840e.


The Influence of decision aids on prostate cancer screening preferences: A randomized survey study.

Weiner AB, Tsai KP, Keeter MK, Victorson DE, Schaeffer EM, Catalona WJ, Kundu SD.

J Urol. 2018 May 28. pii: S0022-5347(18)43270-3. doi: 10.1016/j.juro.2018.05.093. [Epub ahead of print]


MiR-193a-5p and -3p Play a Distinct Role in Gastric Cancer: miR-193a-3p Suppresses Gastric Cancer Cell Growth by Targeting ETS1 and CCND1.

Chou NH, Lo YH, Wang KC, Kang CH, Tsai CY, Tsai KW.

Anticancer Res. 2018 Jun;38(6):3309-3318. doi: 10.21873/anticanres.12596.


Interaction of S17 Antibody with the Functional Binding Region of the Hepatitis B Virus Pre-S2 Epitope.

Chang CY, Chang FL, Chiang CW, Lo YN, Lin TY, Chen WC, Tsai KC, Lee YC.

Viral Immunol. 2018 May 30. doi: 10.1089/vim.2017.0200. [Epub ahead of print]


Comprehensive identification of microRNA arm selection preference in lung cancer: miR-324-5p and -3p serve oncogenic functions in lung cancer.

Lin MH, Chen YZ, Lee MY, Weng KP, Chang HT, Yu SY, Dong BJ, Kuo FR, Hung LT, Liu LF, Chen WS, Tsai KW.

Oncol Lett. 2018 Jun;15(6):9818-9826. doi: 10.3892/ol.2018.8557. Epub 2018 Apr 24.


Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses.

Hsu PH, Chiu DC, Wu KL, Lee PS, Jan JT, Cheng YE, Tsai KC, Cheng TJ, Fang JM.

Eur J Med Chem. 2018 Jun 25;154:314-323. doi: 10.1016/j.ejmech.2018.05.030. Epub 2018 May 21.


Circuit variability interacts with excitatory-inhibitory diversity of interneurons to regulate network encoding capacity.

Tsai KT, Hu CK, Li KW, Hwang WL, Chou YH.

Sci Rep. 2018 May 23;8(1):8027. doi: 10.1038/s41598-018-26286-8.


Consensus on best practice standards for Fracture Liaison Service in the Asia-Pacific region.

Chan DD, Chang LY, Akesson KE, Mitchell P, Chen CH, Michael Lewiecki E, Lee JK, Lau TC, Songpatanasilp T, Lee KB, Kim KJ, Chen JF, Huang KE, Gau YL, Chang YF, Ebeling P, Xia W, Yu W, Suzuki A, Hew FL, Mercado-Asis LB, Chung YS, Tsai KS, Lin GT, Yang RS, Wu CH.

Arch Osteoporos. 2018 May 12;13(1):59. doi: 10.1007/s11657-018-0463-3.


Development of a quantitative real-time RT-PCR assay for detecting Taiwan ferret badger rabies virus in ear tissue of ferret badgers and mice.

Hsu AP, Tseng CH, Lu YT, Shih YH, Chou CH, Chen RS, Tsai KJ, Tu WJ, Cliquet F, Tsai HJ.

J Vet Med Sci. 2018 Apr 30. doi: 10.1292/jvms.17-0539. [Epub ahead of print]


The influence of alendronate and tooth extraction on the incidence of osteonecrosis of the jaw among osteoporotic subjects.

Chiu WY, Yang WS, Chien JY, Lee JJ, Tsai KS.

PLoS One. 2018 Apr 25;13(4):e0196419. doi: 10.1371/journal.pone.0196419. eCollection 2018.


Establishment of a mouse model for the complete mosquito-mediated transmission cycle of Zika virus.

Kuo YP, Tsai KN, Luo YC, Chung PJ, Su YW, Teng Y, Wu MS, Lin YF, Lai CY, Chuang TH, Dai SS, Tseng FC, Hsieh CH, Tsai DJ, Tsai WT, Chen CH, Yu GY.

PLoS Negl Trop Dis. 2018 Apr 18;12(4):e0006417. doi: 10.1371/journal.pntd.0006417. eCollection 2018 Apr.


Isocitrate dehydrogenase 1-snail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability.

Liu WS, Chan SH, Chang HT, Li GC, Tu YT, Tseng HH, Fu TY, Chang HY, Liou HH, Ger LP, Tsai KW.

Breast Cancer Res. 2018 Apr 16;20(1):25. doi: 10.1186/s13058-018-0953-7.


Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells.

Tsai KL, Hung CH, Chan SH, Hsieh PL, Ou HC, Cheng YH, Chu PM.

Mol Nutr Food Res. 2018 Jun;62(11):e1700928. doi: 10.1002/mnfr.201700928. Epub 2018 May 10.


The association between immunoexpression levels of oxidant and antioxidant enzymes and lip squamous cell carcinoma.

Tseng HW, Tseng HH, Liou HH, Tsai KW, Ger LP, Shiue YL.

APMIS. 2018 May;126(5):403-412. doi: 10.1111/apm.12824. Epub 2018 Apr 6.


Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.

Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, Gevaert O, Prunello M, Shen H, Anur P, Chen J, Cheng H, Hayes DN, Bullman S, Pedamallu CS, Ojesina AI, Sadeghi S, Mungall KL, Robertson AG, Benz C, Schultz A, Kanchi RS, Gay CM, Hegde A, Diao L, Wang J, Ma W, Sumazin P, Chiu HS, Chen TW, Gunaratne P, Donehower L, Rader JS, Zuna R, Al-Ahmadie H, Lazar AJ, Flores ER, Tsai KY, Zhou JH, Rustgi AK, Drill E, Shen R, Wong CK; Cancer Genome Atlas Research Network, Stuart JM, Laird PW, Hoadley KA, Weinstein JN, Peto M, Pickering CR, Chen Z, Van Waes C.

Cell Rep. 2018 Apr 3;23(1):194-212.e6. doi: 10.1016/j.celrep.2018.03.063.


Equivalent Efficacies of Reverse Hybrid and Bismuth Quadruple Therapies in Eradication of Helicobacter pylori Infection in a Randomized Controlled Trial.

Hsu PI, Tsay FW, Graham DY, Tsai TJ, Tsai KW, Kao JY, Peng NJ, Kuo CH, Kao SS, Wang HM, Lin TF, Wu DC; Taiwan Acid-related Disease (TARD) Study Group.

Clin Gastroenterol Hepatol. 2018 Mar 31. pii: S1542-3565(18)30328-8. doi: 10.1016/j.cgh.2018.03.031. [Epub ahead of print]


Obstacles to improving outcomes in the treatment of uveal melanoma.

Tsai KK, Bollin KB, Patel SP.

Cancer. 2018 Jul 1;124(13):2693-2703. doi: 10.1002/cncr.31284. Epub 2018 Mar 26. Review.


Development of new core competencies for Taiwanese Emergency Medical Technicians.

Chang YT, Tsai KC, Williams B.

Adv Med Educ Pract. 2018 Mar 7;9:147-158. doi: 10.2147/AMEP.S153403. eCollection 2018.


Liposome-Encapsulated Baicalein Suppressed Lipogenesis and Extracellular Matrix Formation in Hs68 Human Dermal Fibroblasts.

Fang CL, Wang Y, Tsai KH, Chang HI.

Front Pharmacol. 2018 Mar 6;9:155. doi: 10.3389/fphar.2018.00155. eCollection 2018.


Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: A systematic literature review and meta-analysis.

Wu CH, Tu ST, Chang YF, Chan DC, Chien JT, Lin CH, Singh S, Dasari M, Chen JF, Tsai KS.

Bone. 2018 Jun;111:92-100. doi: 10.1016/j.bone.2018.03.018. Epub 2018 Mar 16.


Lyssavirus in Japanese Pipistrelle, Taiwan.

Hu SC, Hsu CL, Lee MS, Tu YC, Chang JC, Wu CH, Lee SH, Ting LJ, Tsai KR, Cheng MC, Tu WJ, Hsu WC.

Emerg Infect Dis. 2018 Apr;24(4):782-785. doi: 10.3201/eid2404.171696.


Ambient air particulates-bound metallic elements sources identifications during winter and summer at a Science Park.

Fang GC, Huang CY, Zhuang YJ, Huang WC, Tsai KH, Xiao YF.

Environ Geochem Health. 2018 Mar 16. doi: 10.1007/s10653-018-0088-x. [Epub ahead of print]


Is Partial or Total Thyroidectomy Associated with Risk of Long-Term Osteoporosis: A Nationwide Population-Based Study.

Hung CL, Yeh CC, Sung PS, Hung CJ, Muo CH, Sung FC, Jou IM, Tsai KJ.

World J Surg. 2018 Mar 14. doi: 10.1007/s00268-018-4573-2. [Epub ahead of print]


Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer.

Tsai KW, Lo YH, Liu H, Yeh CY, Chen YZ, Hsu CW, Chen WS, Wang JH.

Mol Cancer. 2018 Mar 10;17(1):72. doi: 10.1186/s12943-018-0821-1.


Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma.

Chen HY, Lin LT, Wang ML, Tsai KL, Huang PI, Yang YP, Lee YY, Chen YW, Lo WL, Lan YT, Chiou SH, Lin CM, Ma HI, Chen MT.

Biochim Biophys Acta. 2018 May;1864(5 Pt A):1850-1861. doi: 10.1016/j.bbadis.2018.02.017. Epub 2018 Feb 24.


Melanin Bleaching With Warm Hydrogen Peroxide and Integrated Immunohistochemical Analysis: An Automated Platform.

Liu CH, Lin CH, Tsai MJ, Chen YH, Yang SF, Tsai KB.

Int J Surg Pathol. 2018 Feb 1:1066896918756998. doi: 10.1177/1066896918756998. [Epub ahead of print]


3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.

Brignole EJ, Tsai KL, Chittuluru J, Li H, Aye Y, Penczek PA, Stubbe J, Drennan CL, Asturias F.

Elife. 2018 Feb 20;7. pii: e31502. doi: 10.7554/eLife.31502.


Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.

Tsai K, Courtney DG, Cullen BR.

PLoS Pathog. 2018 Feb 15;14(2):e1006919. doi: 10.1371/journal.ppat.1006919. eCollection 2018 Feb.


Unintended Consequences of Evidence-Based Treatment Policy Reform: Is Implementation the Goal or the Strategy for Higher Quality Care?

Park AL, Tsai KH, Guan K, Chorpita BF.

Adm Policy Ment Health. 2018 Jul;45(4):649-660. doi: 10.1007/s10488-018-0853-2.


Wet depositions of mercury during plum rain season in Taiwan.

Fang GC, Huang WC, Zhuang YJ, Huang CY, Tsai KH, Xiao YF.

Environ Geochem Health. 2018 Feb 12. doi: 10.1007/s10653-018-0074-3. [Epub ahead of print]


Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis.

Ma CH, Chiua YC, Wu CH, Jou IM, Tu YK, Hung CH, Hsieh PL, Tsai KL.

Redox Biol. 2018 May;15:504-512. doi: 10.1016/j.redox.2018.01.010. Epub 2018 Feb 3.


Comparative studies on the hypolipidemic, antioxidant and hepatoprotective activities of catechin-enriched green and oolong tea in a double-blind clinical trial.

Venkatakrishnan K, Chiu HF, Cheng JC, Chang YH, Lu YY, Han YC, Shen YC, Tsai KS, Wang CK.

Food Funct. 2018 Feb 21;9(2):1205-1213. doi: 10.1039/c7fo01449j.


First-Line Helicobacter pylori Eradication in Patients with Chronic Kidney Diseases in Taiwan.

Liang CM, Chiu CH, Wang HM, Tai WC, Yao CC, Tsai CE, Kuo CM, Chiu YC, Wu KL, Lee CH, Tsai KL, Huang CF, Chuah SK.

Biomed Res Int. 2017;2017:3762194. doi: 10.1155/2017/3762194. Epub 2017 Dec 11.


Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy.

Liu PF, Tsai KL, Hsu CJ, Tsai WL, Cheng JS, Chang HW, Shiau CW, Goan YG, Tseng HH, Wu CH, Reed JC, Yang LW, Shu CW.

Theranostics. 2018 Jan 1;8(3):830-845. doi: 10.7150/thno.22012. eCollection 2018.


An alternative tool for triaging patients with possible acute coronary symptoms before admission to a chest pain unit.

Tsai KC, Lin RF, Lee C, Li AH.

Am J Emerg Med. 2017 Dec 13. pii: S0735-6757(17)31014-8. doi: 10.1016/j.ajem.2017.12.026. [Epub ahead of print]


Peramivir conjugates as orally available agents against influenza H275Y mutant.

Wang PC, Chiu DC, Jan JT, Huang WI, Tseng YC, Li TT, Cheng TJ, Tsai KC, Fang JM.

Eur J Med Chem. 2018 Feb 10;145:224-234. doi: 10.1016/j.ejmech.2017.12.072. Epub 2017 Dec 24.


Neural Mobilization Attenuates Mechanical Allodynia and Decreases Proinflammatory Cytokine Concentrations in Rats With Painful Diabetic Neuropathy.

Zhu GC, Tsai KL, Chen YW, Hung CH.

Phys Ther. 2018 Apr 1;98(4):214-222. doi: 10.1093/ptj/pzx124.


Biomimetic heterogenous elastic tissue development.

Tsai KJ, Dixon S, Hale LR, Darbyshire A, Martin D, de Mel A.

NPJ Regen Med. 2017 Jun 8;2:16. doi: 10.1038/s41536-017-0021-4. eCollection 2017.


End stage renal disease is associated with development of dementia.

Hung PH, Yeh CC, Hsiao CY, Sung PS, Muo CH, Sung FC, Hung KY, Tsai KJ.

Oncotarget. 2017 Nov 15;8(64):107348-107355. doi: 10.18632/oncotarget.22458. eCollection 2017 Dec 8.


Association between Helicobacter pylori eradication and the risk of coronary heart diseases.

Wang JW, Tseng KL, Hsu CN, Liang CM, Tai WC, Ku MK, Hung TH, Yuan LT, Nguang SH, Yang SC, Wu CK, Chiu CH, Tsai KL, Chang MW, Huang CF, Hsu PI, Wu DC, Chuah SK.

PLoS One. 2018 Jan 2;13(1):e0190219. doi: 10.1371/journal.pone.0190219. eCollection 2018.


Ten-eleven translocation 1 dysfunction reduces 5-hydroxymethylcytosine expression levels in gastric cancer cells.

Wang KC, Kang CH, Tsai CY, Chou NH, Tu YT, Li GC, Lam HC, Liu SI, Chang PM, Lin YH, Tsai KW.

Oncol Lett. 2018 Jan;15(1):278-284. doi: 10.3892/ol.2017.7264. Epub 2017 Oct 25.


Low Levels of IgG Recognizing the α-1-Antitrypsin Peptide and Its Association with Taiwanese Women with Primary Sjögren's Syndrome.

Chang YS, Pan CH, Chang CC, Tsai KL, Chou HW, Chen JH, Lin SH, Lu YY, Tai CC, Lin YF, Lin CY.

Int J Mol Sci. 2017 Dec 18;18(12). pii: E2750. doi: 10.3390/ijms18122750.


Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.

Kennedy EM, Bogerd HP, Kornepati AVR, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR.

Cell Host Microbe. 2017 Dec 13;22(6):830. doi: 10.1016/j.chom.2017.11.010. No abstract available.

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