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Dynamic Protein Allosteric Regulation and Disease.

Nussinov R, Tsai CJ, Jang H.

Adv Exp Med Biol. 2019;1163:25-43. doi: 10.1007/978-981-13-8719-7_2.


Resveratrol treatment improves the altered metabolism and related dysbiosis of gut programed by prenatal high-fat diet and postnatal high-fat diet exposure.

Huang YC, Huang LT, Sheen JM, Hou CY, Yeh YT, Chiang CP, Lin IC, Tiao MM, Tsai CC, Lin YJ, Chen CC, Tain YL, Yu HR.

J Nutr Biochem. 2019 Oct 27;75:108260. doi: 10.1016/j.jnutbio.2019.108260. [Epub ahead of print]


Upregulation of OPA1 by carnosic acid is mediated through induction of IKKγ ubiquitination by parkin and protects against neurotoxicity.

Lin CY, Chen WJ, Fu RH, Tsai CW.

Food Chem Toxicol. 2019 Nov 6:110942. doi: 10.1016/j.fct.2019.110942. [Epub ahead of print]


To examine the associations between medical students' conceptions of learning, strategies to learning, and learning outcome in a medical humanities course.

Chiu YC, Liang JC, Hsu HY, Chu TS, Lin KH, Chen YY, Tsai CC.

BMC Med Educ. 2019 Nov 8;19(1):410. doi: 10.1186/s12909-019-1856-8.


The association between psychological distress and angina pectoris: A population-based study.

Tsai CC, Chuang SY, Hsieh IC, Ho LH, Chu PH, Jeng C.

PLoS One. 2019 Nov 8;14(11):e0224451. doi: 10.1371/journal.pone.0224451. eCollection 2019.


Increased risk of eczema after joint replacement: A population-based retrospective cohort study.

Wu PY, Muo CH, Tsai CH.

Medicine (Baltimore). 2019 Nov;98(45):e17914. doi: 10.1097/MD.0000000000017914.


Psoas abscess associated with aortic endograft infection caused by bacteremia of Listeria monocytogenes: A case report and literature review (CARE Complaint).

Ma JW, Hu SY, Lin TC, Tsai CA.

Medicine (Baltimore). 2019 Nov;98(45):e17885. doi: 10.1097/MD.0000000000017885.


Combination of 1,064-nm Neodymium-doped Yttrium Aluminum Garnet Laser and Steroid Tape Decreases the Total Treatment Time of Hypertrophic Scars: An Analysis of 40 Cases of Cesarean-Section Scars.

Tsai CH, Kao HK, Akaishi S, An-Jou Lin J, Ogawa R.

Dermatol Surg. 2019 Nov 5. doi: 10.1097/DSS.0000000000002235. [Epub ahead of print]


Why Are Some Driver Mutations Rare?

Nussinov R, Tsai CJ, Jang H.

Trends Pharmacol Sci. 2019 Nov 4. pii: S0165-6147(19)30229-9. doi: 10.1016/ [Epub ahead of print] Review.


Associations between Plasma Biomarkers and Cognition in Patients with Alzheimer's Disease and Amnestic Mild Cognitive Impairment: A Cross-Sectional and Longitudinal Study.

Tsai CL, Liang CS, Lee JT, Su MW, Lin CC, Chu HT, Tsai CK, Lin GY, Lin YK, Yang FC.

J Clin Med. 2019 Nov 6;8(11). pii: E1893. doi: 10.3390/jcm8111893.


Ensemble learning of model hyperparameters and spatiotemporal data for calibration of low-cost PM2.5 sensors.

Yin PY, Tsai CC, Day RF, Tung CY, Bhanu B.

Math Biosci Eng. 2019 Jul 29;16(6):6858-6873. doi: 10.3934/mbe.2019343.


Underestimated fracture risk in postmenopausal women-application of the hybrid intervention threshold.

Wang Y, Yu S, Hsu C, Tsai C, Cheng T.

Osteoporos Int. 2019 Nov 6. doi: 10.1007/s00198-019-05201-5. [Epub ahead of print]


Acupuncture Effect and Mechanism for Treating Pain in Patients With Parkinson's Disease.

Yu SW, Lin SH, Tsai CC, Chaudhuri KR, Huang YC, Chen YS, Yeh BY, Wu YR, Wang JJ.

Front Neurol. 2019 Oct 22;10:1114. doi: 10.3389/fneur.2019.01114. eCollection 2019.


The Novel Nuclear Targeting and BFRF1-interacting Domains of BFLF2 are Essential for Efficient EBV Virion Release.

Dai YC, Liao YT, Juan YT, Cheng YY, Su MT, Su YZ, Liu HC, Tsai CH, Lee CP, Chen MR.

J Virol. 2019 Nov 6. pii: JVI.01498-19. doi: 10.1128/JVI.01498-19. [Epub ahead of print]


VEGF-C Gene Polymorphisms Increase Susceptibility to Rheumatoid Arthritis.

Dai C, Kuo SJ, Hu SL, Tsai CH, Huang YL, Huang CC, Wang L, Xu G, Su CM, Tang CH.

Int J Med Sci. 2019 Sep 20;16(10):1397-1403. doi: 10.7150/ijms.34659. eCollection 2019.


Lactobacillus plantarum PS128 Ameliorated Visceral Hypersensitivity in Rats Through the Gut-Brain Axis.

Liu YW, Wang YP, Yen HF, Liu PY, Tzeng WJ, Tsai CF, Lin HC, Lee FY, Jeng OJ, Lu CL, Tsai YC.

Probiotics Antimicrob Proteins. 2019 Nov 5. doi: 10.1007/s12602-019-09595-w. [Epub ahead of print]


Associations between WNT1-inducible signaling pathway protein-1 (WISP-1) genetic polymorphisms and clinical aspects of rheumatoid arthritis among Chinese Han subjects.

Kuo SJ, Hsua PW, Chien SY, Huang CC, Hu SL, Tsai CH, Su CM, Tang CH.

Medicine (Baltimore). 2019 Nov;98(44):e17604. doi: 10.1097/MD.0000000000017604.


Soluble epoxide hydrolase inhibition enhances anti-inflammatory and antioxidative processes, modulates microglia polarization, and promotes recovery after ischemic stroke.

Yeh CF, Chuang TY, Hung YW, Lan MY, Tsai CH, Huang HX, Lin YY.

Neuropsychiatr Dis Treat. 2019 Oct 15;15:2927-2941. doi: 10.2147/NDT.S210403. eCollection 2019.


Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions.

Tsai CH, Li CH, Liao PL, Chang YW, Cheng YW, Kang JJ.

Biochim Biophys Acta Mol Cell Res. 2019 Oct 28;1867(2):118564. doi: 10.1016/j.bbamcr.2019.118564. [Epub ahead of print]


Resistance-associated substitution and ledipasvir/sofosbuvir therapy in Mongolian chronic hepatitis C patients.

Hsu SJ, Enkhzaya S, Lin YY, Tseng TC, Khosbayar T, Tsai CH, Wang TS, Enkhtuya D, Ivshinkhorol D, Naranzul N, Jargalsaikhan B, Amarsanaa J, Baatarkhuu O, Kao JH.

J Formos Med Assoc. 2019 Oct 28. pii: S0929-6646(19)30819-8. doi: 10.1016/j.jfma.2019.10.003. [Epub ahead of print]


The association of matrix metalloproteinas-2 promoter polymorphisms with lung cancer susceptibility in Taiwan.

Chen GL, Wang SC, Shen TC, Tsai CW, Chang WS, Li HT, Wu CN, Chao CY, Hsia TC, Bau DT.

Chin J Physiol. 2019 Sep-Oct;62(5):210-216. doi: 10.4103/CJP.CJP_43_19.


Metabolomic biomarkers in cervicovaginal fluid for detecting endometrial cancer through nuclear magnetic resonance spectroscopy.

Cheng SC, Chen K, Chiu CY, Lu KY, Lu HY, Chiang MH, Tsai CK, Lo CJ, Cheng ML, Chang TC, Lin G.

Metabolomics. 2019 Oct 29;15(11):146. doi: 10.1007/s11306-019-1609-z.


Removal of toluene vapor in the absence and presence of a quorum-sensing molecule in a biotrickling filter and microbial composition shift.

Chen CY, Wang GH, Tsai CT, Tsai TH, Chung YC.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2019 Oct 29:1-10. doi: 10.1080/10934529.2019.1684120. [Epub ahead of print]


Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens.

Carfrae LA, MacNair CR, Brown CM, Tsai CN, Weber BS, Zlitni S, Rao VN, Chun J, Junop MS, Coombes BK, Brown ED.

Nat Microbiol. 2019 Oct 28. doi: 10.1038/s41564-019-0595-2. [Epub ahead of print]


Accuracy assessment of computer-aided three-dimensional simulation and navigation in orthognathic surgery (CASNOS).

Chang YJ, Lai JP, Tsai CY, Wu TJ, Lin SS.

J Formos Med Assoc. 2019 Oct 22. pii: S0929-6646(19)30417-6. doi: 10.1016/j.jfma.2019.09.017. [Epub ahead of print]


Afamin expression in breast cancer.

Wang WK, Tsai CH, Liu YW, Lai CC, Huang CC, Sheen-Chen SM.

Asian J Surg. 2019 Oct 22. pii: S1015-9584(19)30819-X. doi: 10.1016/j.asjsur.2019.09.014. [Epub ahead of print]


Clinical features, management, and outcome of iliopsoas abscess associated with cardiovascular disorders: a hospital-based observational case series study.

Hu SY, Hsieh MS, Chang YT, Huang CC, Tsai CA, Tsai CL, Hsu CY, Shen CH, Chang YZ.

BMC Musculoskelet Disord. 2019 Oct 25;20(1):474. doi: 10.1186/s12891-019-2798-3.


Is It Speech or Song? Effect of Melody Priming on Pitch Perception of Modified Mandarin Speech.

Tsai CG, Li CW.

Brain Sci. 2019 Oct 22;9(10). pii: E286. doi: 10.3390/brainsci9100286.


Retroperitoneal Fibrosis With a Damaged Kidney in IgG4-Related Disease.

Tsai HC, Liao HT, Tsai CY.

J Clin Rheumatol. 2019 Oct 22. doi: 10.1097/RHU.0000000000001181. [Epub ahead of print] No abstract available.


Long-term survival in patients with metastatic head and neck squamous cell carcinoma treated with metastasis-directed therapy.

Beckham TH, Leeman JE, Xie P, Li X, Goldman DA, Zhang Z, Sherman E, McBride S, Riaz N, Lee N, Tsai CJ.

Br J Cancer. 2019 Oct 25. doi: 10.1038/s41416-019-0601-8. [Epub ahead of print]


Endothelial Dysfunction in Primary Aldosteronism.

Chen ZW, Tsai CH, Pan CT, Chou CH, Liao CW, Hung CS, Wu VC, Lin YH; TAIPAI Study Group.

Int J Mol Sci. 2019 Oct 21;20(20). pii: E5214. doi: 10.3390/ijms20205214. Review.


Cross-Talk between Mitochondrial Dysfunction-Provoked Oxidative Stress and Aberrant Noncoding RNA Expression in the Pathogenesis and Pathophysiology of SLE.

Tsai CY, Hsieh SC, Lu CS, Wu TH, Liao HT, Wu CH, Li KJ, Kuo YM, Lee HT, Shen CY, Yu CL.

Int J Mol Sci. 2019 Oct 19;20(20). pii: E5183. doi: 10.3390/ijms20205183. Review.


Treatment of at-level spinal cord injury pain with botulinum toxin A.

Chun A, Levy I, Yang A, Delgado A, Tsai CY, Leung E, Taylor K, Kolakowsky-Hayner S, Huang V, Escalon M, Bryce TN.

Spinal Cord Ser Cases. 2019 Sep 18;5:77. doi: 10.1038/s41394-019-0221-9. eCollection 2019.


The feasibility and usability of a mobile application for performing home evaluations.

Tsai CY, Miller AS, Huang V, Escalon MX, Bryce TN.

Spinal Cord Ser Cases. 2019 Sep 5;5:76. doi: 10.1038/s41394-019-0219-3. eCollection 2019.


U-shaped relationship between left ventricular mass index and estimated glomerular filtration rate in patients with primary aldosteronism.

Liao MT, Liao CW, Tsai CH, Chang YY, Chen ZW, Pan CT, Lin LC, Wu VC, Kuo SF, Wu XM, Hung CS, Lin YH; TAIPAI study group.

J Investig Med. 2019 Oct 19. pii: jim-2019-001057. doi: 10.1136/jim-2019-001057. [Epub ahead of print]


Comparative Renoprotective Effect of Febuxostat and Allopurinol in Pre-Dialysis Stage 5 Chronic Kidney Disease Patients: A Nationwide Database Analysis.

Hsu YO, Wu IW, Chang SH, Lee CC, Tsai CY, Lin CY, Lin WT, Huang YT, Wu CY, Kuo G, Hsiao CY, Lin HL, Yang CC, Yen TH, Chen YC, Hung CC, Tian YC, Kuo CF, Yang CW, Anderson GF, Yang HY.

Clin Pharmacol Ther. 2019 Oct 19. doi: 10.1002/cpt.1697. [Epub ahead of print]


The effect of spatial resolution on the reproducibility of diffusion imaging when controlled signal to noise ratio.

Chen YL, Lin YJ, Lin SH, Tsai CC, Lin YC, Cheng JS, Wang JJ.

Biomed J. 2019 Aug;42(4):268-276. doi: 10.1016/ Epub 2019 Sep 27.


A Randomized-Controlled Phase 2 Study of the MET Antibody Emibetuzumab in Combination with Erlotinib as First-line Treatment for EGFR-mutation Positive NSCLC Patients.

Scagliotti G, Moro-Sibilot D, Kollmeier J, Favaretto A, Cho EK, Grosch H, Kimmich M, Girard N, Tsai CM, Hsia TC, Brighenti M, Schumann C, Wang XA, Wijayawardana SR, Gruver AM, Wallin J, Mansouri K, Wacheck V, Chang GC.

J Thorac Oncol. 2019 Oct 14. pii: S1556-0864(19)33530-0. doi: 10.1016/j.jtho.2019.10.003. [Epub ahead of print]


Pulmonary IL-33 orchestrates innate immune cells to mediate RSV-evoked airway hyperreactivity and eosinophilia.

Wu YH, Lai AC, Chi PY, Thio CL, Chen WY, Tsai CH, Lee YL, Lukacs NW, Chang YJ.

Allergy. 2019 Oct 17. doi: 10.1111/all.14091. [Epub ahead of print]


Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity.

Chen CY, Liao PL, Tsai CH, Chan YJ, Cheng YW, Hwang LL, Lin KH, Yen TL, Li CH.

Part Fibre Toxicol. 2019 Oct 16;16(1):37. doi: 10.1186/s12989-019-0324-2.


Element Effects on High-Entropy Alloy Vacancy and Heterogeneous Lattice Distortion Subjected to Quasi-equilibrium Heating.

Huang EW, Chou HS, Tu KN, Hung WS, Lam TN, Tsai CW, Chiang CY, Lin BH, Yeh AC, Chang SH, Chang YJ, Yang JJ, Li XY, Ku CS, An K, Chang YW, Jao YL.

Sci Rep. 2019 Oct 15;9(1):14788. doi: 10.1038/s41598-019-51297-4.


Protective behaviours of near work and time outdoors in myopia prevalence and progression in myopic children: a 2-year prospective population study.

Huang PC, Hsiao YC, Tsai CY, Tsai DC, Chen CW, Hsu CC, Huang SC, Lin MH, Liou YM.

Br J Ophthalmol. 2019 Oct 15. pii: bjophthalmol-2019-314101. doi: 10.1136/bjophthalmol-2019-314101. [Epub ahead of print]


Smart Phone APP to Restore Optimal Weight (SPAROW): protocol for a randomised controlled trial for women with recent gestational diabetes.

Lim K, Chi C, Chan SY, Lim SL, Ang SM, Yoong JS, Tsai C, Wong SR, Yew TW, Tai ES, Yong EL.

BMC Public Health. 2019 Oct 15;19(1):1287. doi: 10.1186/s12889-019-7691-3.


Identification of Regulatory Host Genes Involved in Sigma Virus Replication Using RNAi Knockdown in Drosophila.

Liao JF, Wu CP, Tang CK, Tsai CW, Rouhová L, Wu YL.

Insects. 2019 Oct 11;10(10). pii: E339. doi: 10.3390/insects10100339.


Differences in neurocognitive performance and metabolic and inflammatory indices in male adults with obesity as a function of regular exercise.

Tsai CL, Pan CY, Chen FC, Huang TH, Tsai MC, Chuang CY.

Exp Physiol. 2019 Nov;104(11):1650-1660. doi: 10.1113/EP087862. Epub 2019 Oct 14.


Platinum-based regimens versus cetuximab in definitive chemoradiation for human papillomavirus-unrelated head and neck cancer.

Beckham TH, Barney C, Healy E, Wolfe AR, Branstetter A, Yaney A, Riaz N, McBride SM, Tsai CJ, Kang J, Yu Y, Chen L, Sherman E, Dunn L, Pfister DG, Tan J, Rupert R, Bonomi M, Zhang Z, Lobaugh SM, Grecula JC, Mitchell DL, Wobb JL, Miller ED, Blakaj DM, Diavolitsis VM, Lee N, Bhatt AD.

Int J Cancer. 2019 Oct 14. doi: 10.1002/ijc.32736. [Epub ahead of print]


Transplant Recipients Using Tacrolimus Had Higher Utilization of Healthcare Services Than Those Receiving Cyclosporine in Taiwan.

Lin YC, Tsai CS, Li IH, Tsai YT, Huang TY, Lee KF, Lin CS, Shih JH, Kao LT.

Front Pharmacol. 2019 Sep 19;10:1074. doi: 10.3389/fphar.2019.01074. eCollection 2019.


Is There a Role for Surgery in Patients with Neuroendocrine Tumors of the Esophagus? A Contemporary View from the NCDB.

Erdem S, Troxler E, Warschkow R, Tsai C, Yerokun B, Schmied B, Stettler C, Blazer DG 3rd, Hartwig M, Worni M, Gloor B.

Ann Surg Oncol. 2019 Oct 11. doi: 10.1245/s10434-019-07847-1. [Epub ahead of print]


Consumption of betel quid contributes to sensorineural hearing impairment through arecoline-induced oxidative stress.

Chan YH, Liu TC, Liao CK, Cheng YF, Tsai CH, Lu YC, Hu CJ, Lin HJ, Lee YL, Wu CC, Hsu CJ.

Sci Rep. 2019 Oct 10;9(1):14554. doi: 10.1038/s41598-019-49815-5.


Quantitative proteomic analysis and functional characterization of Acanthamoeba castellanii exosome-like vesicles.

Lin WC, Tsai CY, Huang JM, Wu SR, Chu LJ, Huang KY.

Parasit Vectors. 2019 Oct 9;12(1):467. doi: 10.1186/s13071-019-3725-z.

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