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The Effect of Implementation of a Nursing Information System: Experiences in a Regional Teaching Hospital in Taiwan.

Liao MC, Chiu JE, Tsai CM.

Comput Inform Nurs. 2020 Feb 19. doi: 10.1097/CIN.0000000000000593. [Epub ahead of print]


A 4-gene leukemic stem cell score can independently predict the prognosis of myelodysplastic syndrome patients.

Wang YH, Lin CC, Yao CY, Hsu CL, Hou HA, Tsai CH, Chou WC, Tien HF.

Blood Adv. 2020 Feb 25;4(4):644-654. doi: 10.1182/bloodadvances.2019001185.


Effects of Highly Oxygenated Water in a Hyperuricemia Rat Model.

Fang CH, Tsai CC, Shyong YJ, Yang CT, Li KY, Lin YW, Chang KC, Wang MH, Wu TM, Lin FH.

J Healthc Eng. 2020 Jan 30;2020:1323270. doi: 10.1155/2020/1323270. eCollection 2020.


Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System.

Chen YJ, Tsai CY, Cheng YM, Nieh SW, Yeh TK, Chen CP, Wang MH, Chou LH, Chiu TY, Liu L, Ho C, Chen CT, Liu TW.

Sci Rep. 2020 Feb 18;10(1):2838. doi: 10.1038/s41598-020-59813-7.


Levels of sex steroid hormones and their receptors in women with preeclampsia.

Lan KC, Lai YJ, Cheng HH, Tsai NC, Su YT, Tsai CC, Hsu TY.

Reprod Biol Endocrinol. 2020 Feb 18;18(1):12. doi: 10.1186/s12958-020-0569-5.


Influence of Different Treatment Strategies on New-Onset Atrial Fibrillation Among Patients With Primary Aldosteronism: A Nationwide Longitudinal Cohort-Based Study.

Pan CT, Liao CW, Tsai CH, Chen ZW, Chen L, Hung CS, Liu YC, Lin PC, Chang CC, Chang YY, Wu VC, Lin YH; TAIPAI study group †.

J Am Heart Assoc. 2020 Mar 3;9(5):e013699. doi: 10.1161/JAHA.119.013699. Epub 2020 Feb 19.


CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.

Wang H, Franco F, Tsui YC, Xie X, Trefny MP, Zappasodi R, Mohmood SR, Fernández-García J, Tsai CH, Schulze I, Picard F, Meylan E, Silverstein R, Goldberg I, Fendt SM, Wolchok JD, Merghoub T, Jandus C, Zippelius A, Ho PC.

Nat Immunol. 2020 Feb 17. doi: 10.1038/s41590-019-0589-5. [Epub ahead of print]


Cardiac calcium dysregulation in mice with chronic kidney disease.

Ke HY, Chin LH, Tsai CS, Lin FZ, Chen YH, Chang YL, Huang SM, Chen YC, Lin CY.

J Cell Mol Med. 2020 Feb 16. doi: 10.1111/jcmm.15066. [Epub ahead of print]


Effect of Floodplain Restoration on Photolytic Removal of Pharmaceuticals.

Hester ET, Lin AY, Tsai CW.

Environ Sci Technol. 2020 Feb 16. doi: 10.1021/acs.est.9b06850. [Epub ahead of print]


HMI-PRED: A Web Server for Structural Prediction of Host-Microbe Interactions Based on Interface Mimicry.

Guven-Maiorov E, Hakouz A, Valjevac S, Keskin O, Tsai CJ, Gursoy A, Nussinov R.

J Mol Biol. 2020 Feb 13. pii: S0022-2836(20)30089-9. doi: 10.1016/j.jmb.2020.01.025. [Epub ahead of print]


Shall i trust the report? Variable performance of Sanger sequencing revealed by deep sequencing on HIV drug resistance mutation detection.

Chen NY, Kao SW, Liu ZH, Wu TS, Tsai CL, Lin HH, Wong WW, Chang YY, Chen SS, Ku SW.

Int J Infect Dis. 2020 Feb 12. pii: S1201-9712(20)30062-X. doi: 10.1016/j.ijid.2020.02.004. [Epub ahead of print]


Treatment Outcome of Bacteremia Due to Non-Carbapenemase-producing Carbapenem-Resistant Klebsiella pneumoniae Bacteremia: Role of Carbapenem Combination Therapy.

Lee NY, Tsai CS, Syue LS, Chen PL, Li CW, Li MC, Ko WC.

Clin Ther. 2020 Feb 12. pii: S0149-2918(20)30030-8. doi: 10.1016/j.clinthera.2020.01.004. [Epub ahead of print]


Proteogenomic Characterization of Endometrial Carcinoma.

Dou Y, Kawaler EA, Cui Zhou D, Gritsenko MA, Huang C, Blumenberg L, Karpova A, Petyuk VA, Savage SR, Satpathy S, Liu W, Wu Y, Tsai CF, Wen B, Li Z, Cao S, Moon J, Shi Z, Cornwell M, Wyczalkowski MA, Chu RK, Vasaikar S, Zhou H, Gao Q, Moore RJ, Li K, Sethuraman S, Monroe ME, Zhao R, Heiman D, Krug K, Clauser K, Kothadia R, Maruvka Y, Pico AR, Oliphant AE, Hoskins EL, Pugh SL, Beecroft SJI, Adams DW, Jarman JC, Kong A, Chang HY, Reva B, Liao Y, Rykunov D, Colaprico A, Chen XS, Czekański A, Jędryka M, Matkowski R, Wiznerowicz M, Hiltke T, Boja E, Kinsinger CR, Mesri M, Robles AI, Rodriguez H, Mutch D, Fuh K, Ellis MJ, DeLair D, Thiagarajan M, Mani DR, Getz G, Noble M, Nesvizhskii AI, Wang P, Anderson ML, Levine DA, Smith RD, Payne SH, Ruggles KV, Rodland KD, Ding L, Zhang B, Liu T, Fenyö D; Clinical Proteomic Tumor Analysis Consortium.

Cell. 2020 Feb 20;180(4):729-748.e26. doi: 10.1016/j.cell.2020.01.026. Epub 2020 Feb 13.


Is Adjuvant Chemotherapy Necessary for Patients with Deficient Mismatch Repair Gastric Cancer?-Autophagy Inhibition Matches the Mismatched.

Tsai CY, Lin TA, Huang SC, Hsu JT, Yeh CN, Chen TC, Chiu CT, Chen JS, Yeh TS.

Oncologist. 2020 Feb 14. doi: 10.1634/theoncologist.2019-0419. [Epub ahead of print]


Long-term outcome and prognostic factors of single-dose Radioiodine Therapy in patients with Graves' disease.

Yang YT, Chen JF, Tung SC, Kuo MC, Weng SW, Chou CK, Shen FC, Chang CM, Tsai CJ, Taso CF, Wang PW.

J Formos Med Assoc. 2020 Feb 10. pii: S0929-6646(20)30018-8. doi: 10.1016/j.jfma.2020.01.014. [Epub ahead of print]


The role of genotype/phenotype at apurinic/apyrimidinic endonuclease Rs1130409 in renal cell carcinoma.

Liao CH, Chang WS, Liao JM, Wu HC, Shen TC, Yang JS, Tsai FJ, Tsai CW, Yu CC, Bau DT.

Chin J Physiol. 2020 Jan-Feb;63(1):43-49. doi: 10.4103/CJP.CJP_72_19.


Diabetes pay-for-performance program can reduce all-cause mortality in patients with newly diagnosed type 2 diabetes mellitus.

Kung FP, Tsai CF, Lu CL, Huang LC, Lu CH.

Medicine (Baltimore). 2020 Feb;99(7):e19139. doi: 10.1097/MD.0000000000019139.


Effects of Andrographolide on Intracellular pH Regulation, Cellular Migration, and Apoptosis in Human Cervical Cancer Cells †.

Loh SH, Tsai YT, Huang SF, Yu TC, Kuo PC, Chao SC, Chou MF, Tsai CS, Lee SP.

Cancers (Basel). 2020 Feb 7;12(2). pii: E387. doi: 10.3390/cancers12020387.


Evaluation of machine learning methods to stroke outcome prediction using a nationwide disease registry.

Lin CH, Hsu KC, Johnson KR, Fann YC, Tsai CH, Sun Y, Lien LM, Chang WL, Chen PL, Lin CL, Hsu CY; Taiwan Stroke Registry Investigators.

Comput Methods Programs Biomed. 2020 Feb 1;190:105381. doi: 10.1016/j.cmpb.2020.105381. [Epub ahead of print]


H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress.

Chong SY, Cutler S, Lin JJ, Tsai CH, Tsai HK, Biggins S, Tsukiyama T, Lo YC, Kao CF.

Nat Commun. 2020 Feb 10;11(1):809. doi: 10.1038/s41467-020-14595-4.


Role of lymphadenectomy, adjuvant chemotherapy, and treatment at high-volume centers in patients with resected pancreatic cancer-a distinct view on lymph node yield.

Warschkow R, Tsai C, Köhn N, Erdem S, Schmied B, Nussbaum DP, Gloor B, Müller SA, Blazer D 3rd, Worni M.

Langenbecks Arch Surg. 2020 Feb 10. doi: 10.1007/s00423-020-01859-2. [Epub ahead of print]


Snellenius manilae bracovirus suppresses the host immune system by regulating extracellular adenosine levels in Spodoptera litura.

Chang Y, Tang CK, Lin YH, Tsai CH, Lu YH, Wu YL.

Sci Rep. 2020 Feb 7;10(1):2096. doi: 10.1038/s41598-020-58375-y.


Ras assemblies and signaling at the membrane.

Nussinov R, Tsai CJ, Jang H.

Curr Opin Struct Biol. 2020 Feb 4;62:140-148. doi: 10.1016/ [Epub ahead of print] Review.


Safety of compression therapy for venous ulcer disease in the setting of congestive heart failure.

Attaran RR, Cavanaugh A, Tsai C, Ahmad T, O' Chaar C, Persing S, Hsia H.

Phlebology. 2020 Feb 6:268355520905178. doi: 10.1177/0268355520905178. [Epub ahead of print] No abstract available.


Chronic hypersensitivity pneumonitis in the southeastern United States: an assessment of how clinicians reached the diagnosis.

Gu JP, Tsai CL, Wysham NG, Huang YT.

BMC Pulm Med. 2020 Feb 5;20(1):32. doi: 10.1186/s12890-020-1072-7.


Neoadjuvant Chemoradiotherapy and Larynx-Preserving Surgery for Cervical Esophageal Cancer.

Dai KY, Yu YC, Leu YS, Chi CW, Chan ML, Tsai CH, Lin HC, Huang WC, Chen YJ.

J Clin Med. 2020 Feb 1;9(2). pii: E387. doi: 10.3390/jcm9020387.


Associations between migraine occurrence and the effect of aura, age at onset, family history, and sex: A cross-sectional study.

Hsu YW, Liang CS, Lee JT, Chu HT, Lee MS, Tsai CL, Lin GY, Lin YK, Ho TH, Yang FC.

PLoS One. 2020 Feb 5;15(2):e0228284. doi: 10.1371/journal.pone.0228284. eCollection 2020.


Bright and fast-response perovskite light-emitting diodes with an ICBA:modified-C60 nanocomposite electrical confinement layer.

Tsai CL, Lu YC, Chiang SE, Yu CM, Cheng HM, Hsu CL, Chiu KY, Chang SH.

Nanoscale. 2020 Feb 14;12(6):4061-4068. doi: 10.1039/c9nr10246a. Epub 2020 Feb 5.


Tetramethylpyrazine reverses high-glucose induced hypoxic effects by negatively regulating HIF-1α induced BNIP3 expression to ameliorate H9c2 cardiomyoblast apoptosis.

Liu SP, Shibu MA, Tsai FJ, Hsu YM, Tsai CH, Chung JG, Yang JS, Tang CH, Wang S, Li Q, Huang CY.

Nutr Metab (Lond). 2020 Jan 31;17:12. doi: 10.1186/s12986-020-0432-x. eCollection 2020.


The Significant Association of MMP-1 Genotypes With Taiwan Pterygium.

Tsai CB, Hsia NY, Wang YC, Wang ZH, Chin YT, Huang TL, Yu CC, Chang WS, Tsai CW, Yin MC, Bau DT.

Anticancer Res. 2020 Feb;40(2):703-707. doi: 10.21873/anticanres.14000.


The Association of MMP7 Promoter Polymorphisms With Gastric Cancer.

Fu CK, Chien YC, Chuang HY, Wang YC, Hwang JJ, Yang MD, Yu CC, Chen JC, Chang WS, Bau DT, Tsai CW.

Anticancer Res. 2020 Feb;40(2):695-702. doi: 10.21873/anticanres.13999.


Stimulants associated with reduced risk of hospitalization for motor vehicle accident injury in patients with obstructive sleep apnea-a nationwide cohort study.

Lin YC, Chen TY, Chien WC, Chung CH, Chang HA, Kao YC, Tsai CS, Lin CS, Tzeng NS.

BMC Pulm Med. 2020 Feb 3;20(1):28. doi: 10.1186/s12890-019-1041-1.


A Strategic Imperative for Promoting Hospital Branding: Analysis of Outcome Indicators.

Shieh GJ, Wu SL, Tsai CF, Chang CS, Chang TH, Lui PW, Yao Y, Sheu WH.

Interact J Med Res. 2020 Jan 22;9(1):e14546. doi: 10.2196/14546.


A new prognostic score for disease progression and mortality in patients with newly diagnosed primary CNS lymphoma.

Liu CJ, Lin SY, Yang CF, Yeh CM, Kuan AS, Wang HY, Tsai CK, Gau JP, Hsiao LT, Chen PM, Liu YC, Hong YC, Ko PS, Liu JH, Lin CH.

Cancer Med. 2020 Feb 3. doi: 10.1002/cam4.2872. [Epub ahead of print]


HEV superinfection accelerates disease progression in patients with chronic HBV infection and increases mortality in those with cirrhosis.

Tseng TC, Liu CJ, Chang CT, Su TH, Yang WT, Tsai CH, Chen CL, Yang HC, Liu CH, Chen PJ, Chen DS, Kao JH.

J Hepatol. 2020 Jan 29. pii: S0168-8278(20)30029-5. doi: 10.1016/j.jhep.2020.01.012. [Epub ahead of print]


Physical and behavioral adaptations to prevent overheating of the living wings of butterflies.

Tsai CC, Childers RA, Nan Shi N, Ren C, Pelaez JN, Bernard GD, Pierce NE, Yu N.

Nat Commun. 2020 Jan 28;11(1):551. doi: 10.1038/s41467-020-14408-8.


Leukocyte telomere length is associated with aggressive prostate cancer in localized prostate cancer patients.

Xu J, Chang WS, Tsai CW, Bau DT, Xu Y, Davis JW, Thompson TC, Logothetis CJ, Gu J.

EBioMedicine. 2020 Jan 22;52:102616. doi: 10.1016/j.ebiom.2019.102616. [Epub ahead of print]


Potential Risk of Higenamine Misuse in Sports: Evaluation of Lotus Plumule Extract Products and a Human Study.

Yen CC, Tung CW, Chang CW, Tsai CC, Hsu MC, Wu YT.

Nutrients. 2020 Jan 21;12(2). pii: E285. doi: 10.3390/nu12020285.


Evidence in Asian Food Industry: Intellectual Capital, Corporate Financial Performance, and Corporate Social Responsibility.

Tsai CH, Mutuc EB.

Int J Environ Res Public Health. 2020 Jan 20;17(2). pii: E663. doi: 10.3390/ijerph17020663.


Cytogenetics and mutations could predict outcome in relapsed and refractory acute myeloid leukemia patients receiving BCL-2 inhibitor venetoclax.

Wang YW, Tsai CH, Lin CC, Tien FM, Chen YW, Lin HY, Yao M, Lin YC, Lin CT, Cheng CL, Tang JL, Chou WC, Hou HA, Tien HF.

Ann Hematol. 2020 Jan 21. doi: 10.1007/s00277-020-03911-z. [Epub ahead of print]


Fluorinated Montmorillonite and 3YSZ as the Inorganic Fillers in Fluoride-Releasing and Rechargeable Dental Composition Resin.

Li KY, Tsai CC, Lin TC, Wang YL, Lin FH, Lin CP.

Polymers (Basel). 2020 Jan 16;12(1). pii: E223. doi: 10.3390/polym12010223.


The presence and impact of herpes virus DNA in recipient cornea and aqueous humor on graft survival following penetrating keratoplasty.

Jeng YT, Tsai CY, Kuo LL, Woung LC, Lin SY, Tsai IL.

J Formos Med Assoc. 2020 Jan 13. pii: S0929-6646(19)31152-0. doi: 10.1016/j.jfma.2019.12.009. [Epub ahead of print]


Physiological and pathophysiological evaluation of baroreflex functionality with concurrent diffusion tensor imaging of its neural circuit in the rat.

Tsai CY, Wu JCC, Chen SM, Lin HH, Chan JYH, Chan SHH.

Biomed J. 2019 Dec;42(6):381-393. doi: 10.1016/ Epub 2019 Dec 24.


Photon-Detection-Probability Simulation Method for CMOS Single-Photon Avalanche Diodes.

Hsieh CA, Tsai CM, Tsui BY, Hsiao BJ, Lin SD.

Sensors (Basel). 2020 Jan 13;20(2). pii: E436. doi: 10.3390/s20020436.


Pregnenolonyl-α-glucoside exhibits marked anti-cancer and CYP17A1 enzymatic inhibitory activities.

Chou FP, Hsu WC, Huang SC, Chang CY, Chiou YS, Tsai CT, Lyu JW, Chen WT, Wu TK.

Chem Commun (Camb). 2020 Feb 6;56(11):1733-1736. doi: 10.1039/c9cc09415f.


Discrepancy Among Self-Reported Adherence, Prescription Refills, and Actual Anticoagulant Control.

Chiu PE, Tsao HM, Tsai CH.

J Nurs Res. 2020 Feb;28(1):e63. doi: 10.1097/jnr.0000000000000374.


Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling.

Muratcioglu S, Aydin C, Odabasi E, Ozdemir ES, Firat-Karalar EN, Jang H, Tsai CJ, Nussinov R, Kavakli IH, Gursoy A, Keskin O.

J Mol Biol. 2020 Jan 10. pii: S0022-2836(20)30018-8. doi: 10.1016/j.jmb.2020.01.002. [Epub ahead of print]


The epidemiology, characteristics and outbreaks of human leptospirosis and the association with animals in Taiwan, 2007-2014: A nationwide database study.

Tsai CT, Lin JN, Lee CH, Sun W, Chang YC, Chen YH, Lai CH.

Zoonoses Public Health. 2020 Mar;67(2):156-166. doi: 10.1111/zph.12667. Epub 2020 Jan 9.


Autoinhibition can identify rare driver mutations and advise pharmacology.

Nussinov R, Tsai CJ, Jang H.

FASEB J. 2020 Jan;34(1):16-29. doi: 10.1096/fj.201901341R. Epub 2019 Nov 22. Review.


Sustainable Recovery of Gaseous Mercury by Adsorption and Electrothermal Desorption Using Activated Carbon Fiber Cloth.

Chen BC, Tsai CY, Pan SY, Chen YT, Hsi HC.

Environ Sci Technol. 2020 Feb 4;54(3):1857-1866. doi: 10.1021/acs.est.9b05114. Epub 2020 Jan 21.


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