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SV40 Hijacks Cellular Transport, Membrane Penetration, and Disassembly Machineries to Promote Infection.

Chen YJ, Liu X, Tsai B.

Viruses. 2019 Oct 5;11(10). pii: E917. doi: 10.3390/v11100917. Review.


Risk factors of Clostridium difficile-associated diarrhea in hospitalized adults: Vary by hospitalized duration.

Hung YP, Lee JC, Tsai BY, Wu JL, Liu HC, Liu HC, Lin HJ, Tsai PJ, Ko WC.

J Microbiol Immunol Infect. 2019 Aug 6. pii: S1684-1182(19)30088-X. doi: 10.1016/j.jmii.2019.07.004. [Epub ahead of print]


How non-enveloped viruses hijack host machineries to cause infection.

Spriggs CC, Harwood MC, Tsai B.

Adv Virus Res. 2019;104:97-122. doi: 10.1016/bs.aivir.2019.05.002. Epub 2019 Jul 2.


Effects of mineral trioxide aggregate and bioceramics on macrophage differentiation and polarization in vitro.

Tu MG, Sun KT, Wang TH, He YZ, Hsia SM, Tsai BH, Shih YH, Shieh TM.

J Formos Med Assoc. 2019 Oct;118(10):1458-1465. doi: 10.1016/j.jfma.2019.07.010. Epub 2019 Jul 26.


Proinsulin misfolding is an early event in the progression to type 2 diabetes.

Arunagiri A, Haataja L, Pottekat A, Pamenan F, Kim S, Zeltser LM, Paton AW, Paton JC, Tsai B, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P.

Elife. 2019 Jun 11;8. pii: e44532. doi: 10.7554/eLife.44532.


Vancomycin-Loaded Nanoparticles Enhance Sporicidal and Antibacterial Efficacy for Clostridium difficile Infection.

Chen YH, Li TJ, Tsai BY, Chen LK, Lai YH, Li MJ, Tsai CY, Tsai PJ, Shieh DB.

Front Microbiol. 2019 May 24;10:1141. doi: 10.3389/fmicb.2019.01141. eCollection 2019.


Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.

Cunningham CN, Williams JM, Knupp J, Arunagiri A, Arvan P, Tsai B.

Mol Cell. 2019 Aug 8;75(3):442-456.e4. doi: 10.1016/j.molcel.2019.05.011. Epub 2019 Jun 5.


Brain Trauma Disrupts Hepatic Lipid Metabolism: Blame It on Fructose?

Rege SD, Royes L, Tsai B, Zhang G, Yang X, Gomez-Pinilla F.

Mol Nutr Food Res. 2019 Aug;63(15):e1801054. doi: 10.1002/mnfr.201801054. Epub 2019 Jun 6.


The ER Membrane Protein Complex Promotes Biogenesis of Dengue and Zika Virus Non-structural Multi-pass Transmembrane Proteins to Support Infection.

Lin DL, Inoue T, Chen YJ, Chang A, Tsai B, Tai AW.

Cell Rep. 2019 May 7;27(6):1666-1674.e4. doi: 10.1016/j.celrep.2019.04.051.


Effects of Social Support on the Stress-Health Relationship: Gender Comparison among Military Personnel.

Hsieh CM, Tsai BK.

Int J Environ Res Public Health. 2019 Apr 12;16(8). pii: E1317. doi: 10.3390/ijerph16081317.


Exposure study on UV-induced degradation of PTFE and ceramic optical diffusers.

Tsai BK, Cooksey CC, Allen DW, White CC, Byrd E, Jacobs D.

Appl Opt. 2019 Feb 10;58(5):1215-1222. doi: 10.1364/AO.58.001215.


Evidence Basis for a Point-of-Care Ultrasound Examination to Refine Referral for Outpatient Echocardiography.

Han PJ, Tsai BT, Martin JW, Keen WD, Waalen J, Kimura BJ.

Am J Med. 2019 Feb;132(2):227-233. doi: 10.1016/j.amjmed.2018.10.012. Epub 2018 Oct 25.


Prenatal Bisphenol A Exposure in Mice Induces Multitissue Multiomics Disruptions Linking to Cardiometabolic Disorders.

Shu L, Meng Q, Diamante G, Tsai B, Chen YW, Mikhail A, Luk H, Ritz B, Allard P, Yang X.

Endocrinology. 2019 Feb 1;160(2):409-429. doi: 10.1210/en.2018-00817.


Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage.

Park JW, Lee JK, Sheu KM, Wang L, Balanis NG, Nguyen K, Smith BA, Cheng C, Tsai BL, Cheng D, Huang J, Kurdistani SK, Graeber TG, Witte ON.

Science. 2018 Oct 5;362(6410):91-95. doi: 10.1126/science.aat5749.


Characterization of Chicken-Derived Single Chain Antibody Fragments against Venom of Naja Naja Atra.

Lee CH, Leu SJ, Lee YC, Liu CI, Lin LT, Mwale PF, Chiang JR, Tsai BY, Chen CC, Hung CS, Yang YY.

Toxins (Basel). 2018 Sep 21;10(10). pii: E383. doi: 10.3390/toxins10100383.


A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers.

Smith BA, Balanis NG, Nanjundiah A, Sheu KM, Tsai BL, Zhang Q, Park JW, Thompson M, Huang J, Witte ON, Graeber TG.

Cell Rep. 2018 Sep 18;24(12):3353-3366.e5. doi: 10.1016/j.celrep.2018.08.062.


Nationwide surveillance of ribotypes and antimicrobial susceptibilities of toxigenic Clostridium difficile isolates with an emphasis on reduced doxycycline and tigecycline susceptibilities among ribotype 078 lineage isolates in Taiwan.

Hung YP, Tsai PJ, Lee YT, Tang HJ, Lin HJ, Liu HC, Lee JC, Tsai BY, Hsueh PR, Ko WC.

Infect Drug Resist. 2018 Aug 15;11:1197-1203. doi: 10.2147/IDR.S162874. eCollection 2018.


The genotypic spectrum of ALDH7A1 mutations resulting in pyridoxine dependent epilepsy: A common epileptic encephalopathy.

Coughlin CR 2nd, Swanson MA, Spector E, Meeks NJL, Kronquist KE, Aslamy M, Wempe MF, van Karnebeek CDM, Gospe SM Jr, Aziz VG, Tsai BP, Gao H, Nagy PL, Hyland K, van Dooren SJM, Salomons GS, Van Hove JLK.

J Inherit Metab Dis. 2019 Mar;42(2):353-361. doi: 10.1002/jimd.12045. Epub 2019 Feb 22.


γ-Secretase promotes membrane insertion of the human papillomavirus L2 capsid protein during virus infection.

Inoue T, Zhang P, Zhang W, Goodner-Bingham K, Dupzyk A, DiMaio D, Tsai B.

J Cell Biol. 2018 Oct 1;217(10):3545-3559. doi: 10.1083/jcb.201804171. Epub 2018 Jul 13.


Bag2 Is a Component of a Cytosolic Extraction Machinery That Promotes Membrane Penetration of a Nonenveloped Virus.

Dupzyk A, Tsai B.

J Virol. 2018 Jul 17;92(15). pii: e00607-18. doi: 10.1128/JVI.00607-18. Print 2018 Aug 1.


Metachronous Hepatic Angiosarcoma Presenting as a Mimic of Recurrent Hepatocellular Carcinoma.

Lau EKC, Tsai B, Morrison H, Deftos M, Lin AY.

J Gastrointest Cancer. 2019 Sep;50(3):647-650. doi: 10.1007/s12029-018-0094-3. No abstract available.


Dynein Engages and Disassembles Cytosol-Localized Simian Virus 40 To Promote Infection.

Ravindran MS, Spriggs CC, Verhey KJ, Tsai B.

J Virol. 2018 May 29;92(12). pii: e00353-18. doi: 10.1128/JVI.00353-18. Print 2018 Jun 15.


Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.

Arunagiri A, Haataja L, Cunningham CN, Shrestha N, Tsai B, Qi L, Liu M, Arvan P.

Ann N Y Acad Sci. 2018 Apr;1418(1):5-19. doi: 10.1111/nyas.13531. Epub 2018 Jan 28. Review.


Preparation and Structural Characterization of Free-Standing Octacalcium-Phosphate-Rich Thin Films.

Tsai BN, Tsao C, Huang SJ, Chang CK, Chan JCC.

J Phys Chem B. 2018 Feb 22;122(7):2082-2089. doi: 10.1021/acs.jpcb.7b11977. Epub 2018 Feb 9.


Single Chain Antibody Fragment against Venom from the Snake Daboia russelii formosensis.

Lee CH, Lee YC, Lee YL, Leu SJ, Lin LT, Chen CC, Chiang JR, Mwale PF, Tsai BY, Hung CS, Yang YY.

Toxins (Basel). 2017 Oct 27;9(11). pii: E347. doi: 10.3390/toxins9110347.


Regulated Erlin-dependent release of the B12 transmembrane J-protein promotes ER membrane penetration of a non-enveloped virus.

Inoue T, Tsai B.

PLoS Pathog. 2017 Jun 14;13(6):e1006439. doi: 10.1371/journal.ppat.1006439. eCollection 2017 Jun.


Exploiting the kinesin-1 molecular motor to generate a virus membrane penetration site.

Ravindran MS, Engelke MF, Verhey KJ, Tsai B.

Nat Commun. 2017 May 24;8:15496. doi: 10.1038/ncomms15496.


SGTA-Dependent Regulation of Hsc70 Promotes Cytosol Entry of Simian Virus 40 from the Endoplasmic Reticulum.

Dupzyk A, Williams JM, Bagchi P, Inoue T, Tsai B.

J Virol. 2017 May 26;91(12). pii: e00232-17. doi: 10.1128/JVI.00232-17. Print 2017 Jun 15.


Efficient and Stable Vacuum-Free-Processed Perovskite Solar Cells Enabled by a Robust Solution-Processed Hole Transport Layer.

Chang CY, Tsai BC, Hsiao YC.

ChemSusChem. 2017 May 9;10(9):1981-1988. doi: 10.1002/cssc.201700340. Epub 2017 Apr 11.


Multidimensional Integrative Genomics Approaches to Dissecting Cardiovascular Disease.

Arneson D, Shu L, Tsai B, Barrere-Cain R, Sun C, Yang X.

Front Cardiovasc Med. 2017 Feb 27;4:8. doi: 10.3389/fcvm.2017.00008. eCollection 2017. Review.


New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.

Qi L, Tsai B, Arvan P.

Trends Cell Biol. 2017 Jun;27(6):430-440. doi: 10.1016/j.tcb.2016.12.002. Epub 2017 Feb 9. Review.


Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.

Cunningham CN, He K, Arunagiri A, Paton AW, Paton JC, Arvan P, Tsai B.

Diabetes. 2017 Mar;66(3):741-753. doi: 10.2337/db16-1338. Epub 2016 Dec 27.


EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus.

Bagchi P, Inoue T, Tsai B.

Elife. 2016 Dec 24;5. pii: e21470. doi: 10.7554/eLife.21470.


Actual use of pocket-sized ultrasound devices for cardiovascular examination by trained physicians during a hospitalist rotation.

Tsai BT, Dahms EB, Waalen J, Kimura BJ.

J Community Hosp Intern Med Perspect. 2016 Dec 15;6(6):33358. doi: 10.3402/jchimp.v6.33358. eCollection 2016.


Predominance of Clostridium difficile Ribotypes 017 and 078 among Toxigenic Clinical Isolates in Southern Taiwan.

Hung YP, Huang IH, Lin HJ, Tsai BY, Liu HC, Liu HC, Lee JC, Wu YH, Tsai PJ, Ko WC.

PLoS One. 2016 Nov 18;11(11):e0166159. doi: 10.1371/journal.pone.0166159. eCollection 2016.


High-performance printable hybrid perovskite solar cells with an easily accessible n-doped fullerene as a cathode interfacial layer.

Chang CY, Tsai BC, Hsiao YC, Huang YC, Tsao CS.

Phys Chem Chem Phys. 2016 Nov 23;18(46):31836-31844.


Laparoscopic Modification of the Osada Technique for Adenomyomectomy.

Tsai BP, McKenna JB, Alanazy R, Rosen D, Cario G, Chou D.

J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S126-S127. doi: 10.1016/j.jmig.2015.08.386. Epub 2015 Oct 15. No abstract available.


How Polyomaviruses Exploit the ERAD Machinery to Cause Infection.

Dupzyk A, Tsai B.

Viruses. 2016 Aug 29;8(9). pii: E242. doi: 10.3390/v8090242. Review.


Zoonotic potential of the Clostridium difficile RT078 family in Taiwan.

Tsai BY, Ko WC, Chen TH, Wu YC, Lan PH, Chen YH, Hung YP, Tsai PJ.

Anaerobe. 2016 Oct;41:125-130. doi: 10.1016/j.anaerobe.2016.06.002. Epub 2016 Jun 9.


Correction: Viruses Utilize Cellular Cues in Distinct Combination to Undergo Systematic Priming and Uncoating.

Ravindran MS, Tsai B.

PLoS Pathog. 2016 Jun 9;12(6):e1005712. doi: 10.1371/journal.ppat.1005712. eCollection 2016 Jun.


Opportunistic intruders: how viruses orchestrate ER functions to infect cells.

Ravindran MS, Bagchi P, Cunningham CN, Tsai B.

Nat Rev Microbiol. 2016 Jul;14(7):407-420. doi: 10.1038/nrmicro.2016.60. Epub 2016 Jun 6. Review.


Parallel mechanisms suppress cochlear bone remodeling to protect hearing.

Jáuregui EJ, Akil O, Acevedo C, Hall-Glenn F, Tsai BS, Bale HA, Liebenberg E, Humphrey MB, Ritchie RO, Lustig LR, Alliston T.

Bone. 2016 Aug;89:7-15. doi: 10.1016/j.bone.2016.04.010. Epub 2016 Apr 13.


Intracellular trafficking of bacterial toxins.

Williams JM, Tsai B.

Curr Opin Cell Biol. 2016 Aug;41:51-6. doi: 10.1016/ Epub 2016 Apr 13. Review.


Viruses Utilize Cellular Cues in Distinct Combination to Undergo Systematic Priming and Uncoating.

Ravindran MS, Tsai B.

PLoS Pathog. 2016 Apr 7;12(4):e1005467. doi: 10.1371/journal.ppat.1005467. eCollection 2016 Apr. Review. No abstract available. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005712.


The Grp170 nucleotide exchange factor executes a key role during ERAD of cellular misfolded clients.

Inoue T, Tsai B.

Mol Biol Cell. 2016 May 15;27(10):1650-62. doi: 10.1091/mbc.E16-01-0033. Epub 2016 Mar 30.


Motorcycle helmet use and the risk of head, neck, and fatal injury: Revisiting the Hurt Study.

Rice TM, Troszak L, Ouellet JV, Erhardt T, Smith GS, Tsai BW.

Accid Anal Prev. 2016 Jun;91:200-7. doi: 10.1016/j.aap.2016.03.002. Epub 2016 Mar 19.


Potentially hypervirulent Clostridium difficile PCR ribotype 078 lineage isolates in pigs and possible implications for humans in Taiwan.

Wu YC, Lee JJ, Tsai BY, Liu YF, Chen CM, Tien N, Tsai PJ, Chen TH.

Int J Med Microbiol. 2016 Feb;306(2):115-22. doi: 10.1016/j.ijmm.2016.02.002. Epub 2016 Feb 12.


Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.

Haataja L, Manickam N, Soliman A, Tsai B, Liu M, Arvan P.

Diabetes. 2016 Apr;65(4):1050-60. doi: 10.2337/db15-1345. Epub 2016 Jan 28.


Investigation of fibrous cap stresses on vulnerable plaques leading to heart attacks.

Hsiao HM, Wu YY, Tsai BC, Chen YC, Cheng YH.

Technol Health Care. 2015;24 Suppl 1:S155-61. doi: 10.3233/THC-151064.


Executive functioning in TBI from rehabilitation to social reintegration: COMPASS (goal,) a randomized controlled trial (grant: 1I01RX000637-01A3 by the VA ORD RR&D, 2013-2016).

Libin AV, Scholten J, Schladen MM, Danford E, Shara N, Penk W, Grafman J, Resnik L, Bruner D, Cichon S, Philmon M, Tsai B, Blackman M, Dromerick A.

Mil Med Res. 2015 Nov 30;2:32. doi: 10.1186/s40779-015-0061-2. eCollection 2015.

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