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Items: 24


Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness.

Barr IG, Donis RO, Katz JM, McCauley JW, Odagiri T, Trusheim H, Tsai TF, Wentworth DE.

NPJ Vaccines. 2018 Oct 9;3:44. doi: 10.1038/s41541-018-0079-z. eCollection 2018. Review.


Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturing.

Donis RO; Influenza Cell Culture Working Group, Davis CT, Foust A, Hossain MJ, Johnson A, Klimov A, Loughlin R, Xu X, Tsai T, Blayer S, Trusheim H, Colegate T, Fox J, Taylor B, Hussain A, Barr I, Baas C, Louwerens J, Geuns E, Lee MS, Venhuizen O, Neumeier E, Ziegler T.

Vaccine. 2014 Nov 12;32(48):6583-90. doi: 10.1016/j.vaccine.2014.06.045. Epub 2014 Jun 24.


Synthetic generation of influenza vaccine viruses for rapid response to pandemics.

Dormitzer PR, Suphaphiphat P, Gibson DG, Wentworth DE, Stockwell TB, Algire MA, Alperovich N, Barro M, Brown DM, Craig S, Dattilo BM, Denisova EA, De Souza I, Eickmann M, Dugan VG, Ferrari A, Gomila RC, Han L, Judge C, Mane S, Matrosovich M, Merryman C, Palladino G, Palmer GA, Spencer T, Strecker T, Trusheim H, Uhlendorff J, Wen Y, Yee AC, Zaveri J, Zhou B, Becker S, Donabedian A, Mason PW, Glass JI, Rappuoli R, Venter JC.

Sci Transl Med. 2013 May 15;5(185):185ra68. doi: 10.1126/scitranslmed.3006368.


Safety of MDCK cell culture-based influenza vaccines.

Gregersen JP, Schmitt HJ, Trusheim H, Bröker M.

Future Microbiol. 2011 Feb;6(2):143-52. doi: 10.2217/fmb.10.161. Review.


[Prion safety of medicinal products using the example of an influenza vaccine produced in a cell line].

Trusheim H, Gregersen JP, Schmitt HJ, Bröker M.

Med Monatsschr Pharm. 2010 Sep;33(9):337-42. Review. German.


Exploring synergies between academia and vaccine manufacturers: a pilot study on how to rapidly produce vaccines to combat emerging pathogens.

Strecker T, Uhlendorff J, Diederich S, Lenz-Bauer C, Trusheim H, Roth B, Kolesnikova L, Aepinus C, Dornow R, Gerlach J, Matrosovich M, Valley U, Eickmann M, Becker S.

Clin Chem Lab Med. 2012 May 23;50(7):1275-9. doi: 10.1515/cclm-2011-0650.


Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs.

Suphaphiphat P, Franti M, Hekele A, Lilja A, Spencer T, Settembre E, Palmer G, Crotta S, Tuccino AB, Keiner B, Trusheim H, Balabanis K, Sackal M, Rothfeder M, Mandl CW, Dormitzer PR, Mason PW.

Virol J. 2010 Jul 14;7:157. doi: 10.1186/1743-422X-7-157.


[Safety of cell culture-based influenza vaccines].

Schmitt HJ, Gregersen JP, Trusheim H, Bröker M.

Med Monatsschr Pharm. 2010 Jan;33(1):4-10. Review. German.


Human RNA polymerase I-driven reverse genetics for influenza a virus in canine cells.

Suphaphiphat P, Keiner B, Trusheim H, Crotta S, Tuccino AB, Zhang P, Dormitzer PR, Mason PW, Franti M.

J Virol. 2010 Apr;84(7):3721-5. doi: 10.1128/JVI.01925-09. Epub 2010 Jan 13.


Current challenges in implementing cell-derived influenza vaccines: implications for production and regulation, July 2007, NIBSC, Potters Bar, UK.

Minor PD, Engelhardt OG, Wood JM, Robertson JS, Blayer S, Colegate T, Fabry L, Heldens JG, Kino Y, Kistner O, Kompier R, Makizumi K, Medema J, Mimori S, Ryan D, Schwartz R, Smith JS, Sugawara K, Trusheim H, Tsai TF, Krause R.

Vaccine. 2009 May 14;27(22):2907-13. doi: 10.1016/j.vaccine.2009.02.064. Epub 2009 Feb 27. Review.


Canine MDCK cell lines are refractory to infection with human and mouse prions.

Polymenidou M, Trusheim H, Stallmach L, Moos R, Julius C, Miele G, Lenz-Bauer C, Aguzzi A.

Vaccine. 2008 May 19;26(21):2601-14. doi: 10.1016/j.vaccine.2008.03.035. Epub 2008 Apr 9.


Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation.

Kannemeier C, Shibamiya A, Nakazawa F, Trusheim H, Ruppert C, Markart P, Song Y, Tzima E, Kennerknecht E, Niepmann M, von Bruehl ML, Sedding D, Massberg S, Günther A, Engelmann B, Preissner KT.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6388-93. Epub 2007 Apr 3.


A positively charged cluster in the epidermal growth factor-like domain of Factor VII-activating protease (FSAP) is essential for polyanion binding.

Altincicek B, Shibamiya A, Trusheim H, Tzima E, Niepmann M, Linder D, Preissner KT, Kanse SM.

Biochem J. 2006 Mar 15;394(Pt 3):687-92.


Evidence for an RNA chaperone function of polypyrimidine tract-binding protein in picornavirus translation.

Song Y, Tzima E, Ochs K, Bassili G, Trusheim H, Linder M, Preissner KT, Niepmann M.

RNA. 2005 Dec;11(12):1809-24.


Extracellular RNA is a natural cofactor for the (auto-)activation of Factor VII-activating protease (FSAP).

Nakazawa F, Kannemeier C, Shibamiya A, Song Y, Tzima E, Schubert U, Koyama T, Niepmann M, Trusheim H, Engelmann B, Preissner KT.

Biochem J. 2005 Feb 1;385(Pt 3):831-8.


Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha.

Hallmann D, Trümper K, Trusheim H, Ueki K, Kahn CR, Cantley LC, Fruman DA, Hörsch D.

J Biol Chem. 2003 Feb 14;278(7):5099-108. Epub 2002 Nov 14.


DUG is a novel homologue of translation initiation factor 4G that binds eIF4A.

Göke A, Göke R, Knolle A, Trusheim H, Schmidt H, Wilmen A, Carmody R, Göke B, Chen YH.

Biochem Biophys Res Commun. 2002 Sep 13;297(1):78-82.


Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling.

Trümper A, Trümper K, Trusheim H, Arnold R, Göke B, Hörsch D.

Mol Endocrinol. 2001 Sep;15(9):1559-70.


Integrative mitogenic role of protein kinase B/Akt in beta-cells.

Trümper K, Trümper A, Trusheim H, Arnold R, Göke B, Hörsch D.

Ann N Y Acad Sci. 2000;921:242-50.


Gene expression of the human glucagon-like peptide-1 receptor is regulated by Sp1 and Sp3.

Wildhage I, Trusheim H, Göke B, Lankat-Buttgereit B.

Endocrinology. 1999 Feb;140(2):624-31.


[Modification of the Hegar needle for vascular surgery].

Trusheim H.

Chirurg. 1981 Dec;52(12):795-6. German. No abstract available.


[Experiences with a heated covering for x-ray tables].

Viehweger G, Trusheim H.

Rontgenpraxis. 1980 Jun;33(6):153-5. German. No abstract available.


[Prostaglandin-induced vascular motility and its possible significance in hypertension].

Laven R, Bruch HP, Schmidt E, Trusheim H.

Verh Dtsch Ges Kreislaufforsch. 1977;43:197. German. No abstract available.


[Proceedings: Urgent measures in vascular surgery for renal insufficiency].

Trusheim H, Rüppell V, Ackermann R, Sperling M.

MMW Munch Med Wochenschr. 1975 Feb 28;117(9):364-5. German. No abstract available.


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