Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 49

1.

Oligomerization of Hsp70: Current Perspectives on Regulation and Function.

Takakuwa JE, Nitika, Knighton LE, Truman AW.

Front Mol Biosci. 2019 Sep 4;6:81. doi: 10.3389/fmolb.2019.00081. eCollection 2019. Review.

2.

Dynamic remodeling of the interactomes of Nematostella vectensis Hsp70 isoforms under heat shock.

Knighton LE, Nitika, Waller SJ, Strom O, Wolfgeher D, Reitzel AM, Truman AW.

J Proteomics. 2019 Aug 30;206:103416. doi: 10.1016/j.jprot.2019.103416. Epub 2019 Jun 21.

PMID:
31233900
3.

Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer.

Ricco N, Flor A, Wolfgeher D, Efimova EV, Ramamurthy A, Appelbe OK, Brinkman J, Truman AW, Spiotto MT, Kron SJ.

Mol Oncol. 2019 Sep;13(9):1927-1943. doi: 10.1002/1878-0261.12535. Epub 2019 Jul 26.

4.

Not quite the SSAme: unique roles for the yeast cytosolic Hsp70s.

Lotz SK, Knighton LE, Nitika, Jones GW, Truman AW.

Curr Genet. 2019 Oct;65(5):1127-1134. doi: 10.1007/s00294-019-00978-8. Epub 2019 Apr 24. Review.

PMID:
31020385
5.

Activation of Secondary Metabolite Gene Clusters in Streptomyces clavuligerus by the PimM Regulator of Streptomyces natalensis.

Martínez-Burgo Y, Santos-Aberturas J, Rodríguez-García A, Barreales EG, Tormo JR, Truman AW, Reyes F, Aparicio JF, Liras P.

Front Microbiol. 2019 Mar 26;10:580. doi: 10.3389/fmicb.2019.00580. eCollection 2019.

6.

Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool.

Santos-Aberturas J, Chandra G, Frattaruolo L, Lacret R, Pham TH, Vior NM, Eyles TH, Truman AW.

Nucleic Acids Res. 2019 May 21;47(9):4624-4637. doi: 10.1093/nar/gkz192.

7.

Novel insights into molecular chaperone regulation of ribonucleotide reductase.

Knighton LE, Delgado LE, Truman AW.

Curr Genet. 2019 Apr;65(2):477-482. doi: 10.1007/s00294-018-0916-7. Epub 2018 Dec 5. Review.

PMID:
30519713
8.

The Hsp70 co-chaperone Ydj1/HDJ2 regulates ribonucleotide reductase activity.

Sluder IT, Nitika, Knighton LE, Truman AW.

PLoS Genet. 2018 Nov 19;14(11):e1007462. doi: 10.1371/journal.pgen.1007462. eCollection 2018 Nov.

9.

Characterizing functional differences in sea anemone Hsp70 isoforms using budding yeast.

Waller SJ, Knighton LE, Crabtree LM, Perkins AL, Reitzel AM, Truman AW.

Cell Stress Chaperones. 2018 Sep;23(5):933-941. doi: 10.1007/s12192-018-0900-7. Epub 2018 Apr 25.

10.

Rapid and Robust Yeast-Mediated Pathway Refactoring Generates Multiple New Bottromycin-Related Metabolites.

Eyles TH, Vior NM, Truman AW.

ACS Synth Biol. 2018 May 18;7(5):1211-1218. doi: 10.1021/acssynbio.8b00038. Epub 2018 Apr 30.

11.

Discovery and Biosynthesis of the Antibiotic Bicyclomycin in Distantly Related Bacterial Classes.

Vior NM, Lacret R, Chandra G, Dorai-Raj S, Trick M, Truman AW.

Appl Environ Microbiol. 2018 Apr 16;84(9). pii: e02828-17. doi: 10.1128/AEM.02828-17. Print 2018 May 1.

12.

Warhead biosynthesis and the origin of structural diversity in hydroxamate metalloproteinase inhibitors.

Leipoldt F, Santos-Aberturas J, Stegmann DP, Wolf F, Kulik A, Lacret R, Popadić D, Keinhörster D, Kirchner N, Bekiesch P, Gross H, Truman AW, Kaysser L.

Nat Commun. 2017 Dec 6;8(1):1965. doi: 10.1038/s41467-017-01975-6.

13.

Macroamidine Formation in Bottromycins Is Catalyzed by a Divergent YcaO Enzyme.

Franz L, Adam S, Santos-Aberturas J, Truman AW, Koehnke J.

J Am Chem Soc. 2017 Dec 20;139(50):18158-18161. doi: 10.1021/jacs.7b09898. Epub 2017 Dec 5.

PMID:
29206037
14.

Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer.

Dushukyan N, Dunn DM, Sager RA, Woodford MR, Loiselle DR, Daneshvar M, Baker-Williams AJ, Chisholm JD, Truman AW, Vaughan CK, Haystead TA, Bratslavsky G, Bourboulia D, Mollapour M.

Cell Rep. 2017 Nov 14;21(7):1883-1895. doi: 10.1016/j.celrep.2017.10.074.

15.

Cracking the Chaperone Code: Cellular Roles for Hsp70 Phosphorylation.

Nitika, Truman AW.

Trends Biochem Sci. 2017 Dec;42(12):932-935. doi: 10.1016/j.tibs.2017.10.002. Epub 2017 Nov 5.

16.

A Genomics-Based Approach Identifies a Thioviridamide-Like Compound with Selective Anticancer Activity.

Frattaruolo L, Lacret R, Cappello AR, Truman AW.

ACS Chem Biol. 2017 Nov 17;12(11):2815-2822. doi: 10.1021/acschembio.7b00677. Epub 2017 Oct 12.

PMID:
28968491
17.

Endogenous epitope tagging of heat shock protein 70 isoform Hsc70 using CRISPR/Cas9.

Nitika, Truman AW.

Cell Stress Chaperones. 2018 May;23(3):347-355. doi: 10.1007/s12192-017-0845-2. Epub 2017 Sep 24.

18.

Cyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptides.

Truman AW.

Beilstein J Org Chem. 2016 Jun 20;12:1250-68. doi: 10.3762/bjoc.12.120. eCollection 2016. Review.

19.

Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics.

Crone WJ, Vior NM, Santos-Aberturas J, Schmitz LG, Leeper FJ, Truman AW.

Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9639-43. doi: 10.1002/anie.201604304. Epub 2016 Jul 4.

20.

Characterization of the Post-Assembly Line Tailoring Processes in Teicoplanin Biosynthesis.

Yushchuk O, Ostash B, Pham TH, Luzhetskyy A, Fedorenko V, Truman AW, Horbal L.

ACS Chem Biol. 2016 Aug 19;11(8):2254-64. doi: 10.1021/acschembio.6b00018. Epub 2016 Jun 20.

PMID:
27285718
21.

Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.

Woodford MR, Truman AW, Dunn DM, Jensen SM, Cotran R, Bullard R, Abouelleil M, Beebe K, Wolfgeher D, Wierzbicki S, Post DE, Caza T, Tsutsumi S, Panaretou B, Kron SJ, Trepel JB, Landas S, Prodromou C, Shapiro O, Stetler-Stevenson WG, Bourboulia D, Neckers L, Bratslavsky G, Mollapour M.

Cell Rep. 2016 Feb 2;14(4):872-884. doi: 10.1016/j.celrep.2015.12.084. Epub 2016 Jan 21.

22.

The frontline antibiotic vancomycin induces a zinc starvation response in bacteria by binding to Zn(II).

Zarkan A, Macklyne HR, Truman AW, Hesketh AR, Hong HJ.

Sci Rep. 2016 Jan 22;6:19602. doi: 10.1038/srep19602.

23.

The dynamic interactome of human Aha1 upon Y223 phosphorylation.

Wolfgeher D, Dunn DM, Woodford MR, Bourboulia D, Bratslavsky G, Mollapour M, Kron SJ, Truman AW.

Data Brief. 2015 Nov 6;5:752-5. doi: 10.1016/j.dib.2015.10.028. eCollection 2015 Dec.

24.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

25.

c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells.

Dunn DM, Woodford MR, Truman AW, Jensen SM, Schulman J, Caza T, Remillard TC, Loiselle D, Wolfgeher D, Blagg BS, Franco L, Haystead TA, Daturpalli S, Mayer MP, Trepel JB, Morgan RM, Prodromou C, Kron SJ, Panaretou B, Stetler-Stevenson WG, Landas SK, Neckers L, Bratslavsky G, Bourboulia D, Mollapour M.

Cell Rep. 2015 Aug 11;12(6):1006-18. doi: 10.1016/j.celrep.2015.07.004. Epub 2015 Jul 30.

26.

The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage.

Truman AW, Kristjansdottir K, Wolfgeher D, Ricco N, Mayampurath A, Volchenboum SL, Clotet J, Kron SJ.

Data Brief. 2014 Nov 7;2:12-5. doi: 10.1016/j.dib.2014.10.006. eCollection 2015 Mar.

27.

Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase.

Truman AW, Kristjansdottir K, Wolfgeher D, Ricco N, Mayampurath A, Volchenboum SL, Clotet J, Kron SJ.

J Proteomics. 2015 Jan 1;112:285-300. doi: 10.1016/j.jprot.2014.09.028. Epub 2014 Oct 18.

28.

The pathway-specific regulatory genes, tei15* and tei16*, are the master switches of teicoplanin production in Actinoplanes teichomyceticus.

Horbal L, Kobylyanskyy A, Truman AW, Zaburranyi N, Ostash B, Luzhetskyy A, Marinelli F, Fedorenko V.

Appl Microbiol Biotechnol. 2014 Nov;98(22):9295-309. doi: 10.1007/s00253-014-5969-z. Epub 2014 Aug 9.

PMID:
25104028
29.

Antibiotic resistance mechanisms inform discovery: identification and characterization of a novel amycolatopsis strain producing ristocetin.

Truman AW, Kwun MJ, Cheng J, Yang SH, Suh JW, Hong HJ.

Antimicrob Agents Chemother. 2014 Oct;58(10):5687-95. doi: 10.1128/AAC.03349-14. Epub 2014 Jul 14.

30.

DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast.

Balogun FO, Truman AW, Kron SJ.

DNA Repair (Amst). 2013 Sep;12(9):751-60. doi: 10.1016/j.dnarep.2013.06.003. Epub 2013 Jul 6.

31.

The yin and yang of cyclin control by nutrients.

Jiménez J, Truman AW, Menoyo S, Kron SJ, Clotet J.

Cell Cycle. 2013 Mar 15;12(6):865-6. doi: 10.4161/cc.24217. Epub 2013 Mar 7. No abstract available.

32.

CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.

Truman AW, Kristjansdottir K, Wolfgeher D, Hasin N, Polier S, Zhang H, Perrett S, Prodromou C, Jones GW, Kron SJ.

Cell. 2012 Dec 7;151(6):1308-18. doi: 10.1016/j.cell.2012.10.051.

33.

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA.

Nat Prod Rep. 2013 Jan;30(1):108-60. doi: 10.1039/c2np20085f. Review.

34.

Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.

Mollapour M, Tsutsumi S, Truman AW, Xu W, Vaughan CK, Beebe K, Konstantinova A, Vourganti S, Panaretou B, Piper PW, Trepel JB, Prodromou C, Pearl LH, Neckers L.

Mol Cell. 2011 Mar 18;41(6):672-81. doi: 10.1016/j.molcel.2011.02.011.

35.

Epigenetic modifications in double-strand break DNA damage signaling and repair.

Rossetto D, Truman AW, Kron SJ, Côté J.

Clin Cancer Res. 2010 Sep 15;16(18):4543-52. doi: 10.1158/1078-0432.CCR-10-0513. Epub 2010 Sep 7. Review.

36.

Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator.

Kim KY, Truman AW, Caesar S, Schlenstedt G, Levin DE.

Mol Biol Cell. 2010 May 1;21(9):1609-19. doi: 10.1091/mbc.E09-11-0923. Epub 2010 Mar 10.

37.

Mechanism of Mpk1 mitogen-activated protein kinase binding to the Swi4 transcription factor and its regulation by a novel caffeine-induced phosphorylation.

Truman AW, Kim KY, Levin DE.

Mol Cell Biol. 2009 Dec;29(24):6449-61. doi: 10.1128/MCB.00794-09. Epub 2009 Oct 5.

38.

Chimeric glycosyltransferases for the generation of hybrid glycopeptides.

Truman AW, Dias MV, Wu S, Blundell TL, Huang F, Spencer JB.

Chem Biol. 2009 Jun 26;16(6):676-85. doi: 10.1016/j.chembiol.2009.04.013.

39.

The role of cep15 in the biosynthesis of chloroeremomycin: reactivation of an ancestral catalytic function.

Truman AW, Fan Q, Röttgen M, Stegmann E, Leadlay PF, Spencer JB.

Chem Biol. 2008 May;15(5):476-84. doi: 10.1016/j.chembiol.2008.03.019.

40.

Yeast Mpk1 mitogen-activated protein kinase activates transcription through Swi4/Swi6 by a noncatalytic mechanism that requires upstream signal.

Kim KY, Truman AW, Levin DE.

Mol Cell Biol. 2008 Apr;28(8):2579-89. doi: 10.1128/MCB.01795-07. Epub 2008 Feb 11.

41.
42.

In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity.

Truman AW, Millson SH, Nuttall JM, Mollapour M, Prodromou C, Piper PW.

Eukaryot Cell. 2007 Apr;6(4):744-52. Epub 2007 Feb 9.

43.

Characterization of the enzyme BtrD from Bacillus circulans and revision of its functional assignment in the biosynthesis of butirosin.

Truman AW, Huang F, Llewellyn NM, Spencer JB.

Angew Chem Int Ed Engl. 2007;46(9):1462-4. No abstract available.

PMID:
17226887
44.
45.

Identification of a deacetylase involved in the maturation of teicoplanin.

Truman AW, Robinson L, Spencer JB.

Chembiochem. 2006 Nov;7(11):1670-5. No abstract available.

PMID:
17009278
46.

Expressed in the yeast Saccharomyces cerevisiae, human ERK5 is a client of the Hsp90 chaperone that complements loss of the Slt2p (Mpk1p) cell integrity stress-activated protein kinase.

Truman AW, Millson SH, Nuttall JM, King V, Mollapour M, Prodromou C, Pearl LH, Piper PW.

Eukaryot Cell. 2006 Nov;5(11):1914-24. Epub 2006 Sep 1.

48.

Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach.

Millson SH, Truman AW, Wolfram F, King V, Panaretou B, Prodromou C, Pearl LH, Piper PW.

Cell Stress Chaperones. 2004 Winter;9(4):359-68.

49.

Vectors for N- or C-terminal positioning of the yeast Gal4p DNA binding or activator domains.

Millson SH, Truman AW, Piper PW.

Biotechniques. 2003 Jul;35(1):60-4. No abstract available.

Supplemental Content

Loading ...
Support Center