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Items: 1 to 50 of 134

1.

Design, synthesis and biological evaluation of indane derived GPR40 agoPAMs.

Pio B, Chobanian HR, Guo Y, Josien H, Hagmann WK, Miller M, Trujillo ME, Kirkland M, Kosinski D, Mane J, Pachanski M, Cheewatrakoolpong B, Ashley E, Orr R, Wright MJ, Bugianesi R, Souza S, Zhang X, Di Salvo J, Weinglass AB, Tschirret-Guth R, Samuel K, Chen Q, Shang J, Lamca J, Ehrhart J, Nargund R, Howard AD, Colletti SL.

Bioorg Med Chem Lett. 2019 Jul 15;29(14):1842-1848. doi: 10.1016/j.bmcl.2019.04.050. Epub 2019 May 2.

PMID:
31109791
2.

Industrialization of Quantitative Systems Pharmacology.

Topp B, Trujillo ME, Sinha V.

CPT Pharmacometrics Syst Pharmacol. 2019 Jun;8(6):356-358. doi: 10.1002/psp4.12427. Epub 2019 Jun 6. No abstract available.

3.

An integrated bioaugmentation/electrocoagulation concept for olive mill wastewater management and the reuse in irrigation of biofuel plants: a pilot study.

Abdulla HM, El-Shatoury SA, El-Shahawy AA, Ghorab SA, Nasr M, Trujillo ME.

Environ Sci Pollut Res Int. 2019 Jun;26(16):15803-15815. doi: 10.1007/s11356-019-04893-w. Epub 2019 Apr 5.

PMID:
30953323
4.

A study of three bacteria isolated from marine sediment and description of Micromonospora globispora sp. nov.

Carro L, Veyisoglu A, Cetin D, Igual JM, Klenk HP, Trujillo ME, Sahin N.

Syst Appl Microbiol. 2019 Mar;42(2):190-197. doi: 10.1016/j.syapm.2018.11.003. Epub 2018 Nov 16.

PMID:
30528275
5.

DORA Editorial.

Parish T, Harris M, Fry N, Mathee K, Trujillo ME, Bentley S, Thomson N.

Microbiology. 2019 Feb;165(2):125-126. doi: 10.1099/mic.0.000751. Epub 2018 Dec 5. No abstract available.

PMID:
30516468
6.

DORA Editorial.

Parish T, Harris M, Fry N, Mathee K, Trujillo ME, Bentley S, Thomson N.

J Gen Virol. 2019 Jan;100(1):1-2. doi: 10.1099/jgv.0.001191. Epub 2018 Dec 5. No abstract available.

PMID:
30516467
7.

DORA Editorial.

Parish T, Harris M, Fry N, Mathee K, Trujillo ME, Bentley S, Thomson N.

J Med Microbiol. 2019 Feb;68(2):117-118. doi: 10.1099/jmm.0.000887. Epub 2018 Dec 5. No abstract available.

PMID:
30516466
8.

DORA Editorial.

Parish T, Harris M, Fry N, Mathee K, Trujillo ME, Bentley S, Thomson N.

Microb Genom. 2018 Dec;4(12). doi: 10.1099/mgen.0.000238. Epub 2018 Dec 5. No abstract available.

9.

DORA Editorial.

Parish T, Harris M, Fry N, Mathee K, Trujillo ME, Bentley S, Thomson N.

Int J Syst Evol Microbiol. 2019 Jan;69(1):1-2. doi: 10.1099/ijsem.0.003172. No abstract available.

PMID:
30516461
10.

Preparation of the Validation Lists and the role of the List Editors.

Trujillo ME, Oren A, Garrity GM.

Int J Syst Evol Microbiol. 2019 Jan;69(1):3-4. doi: 10.1099/ijsem.0.003106. Epub 2018 Nov 16.

PMID:
30444472
11.

Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs.

Chen HY, Plummer CW, Xiao D, Chobanian HR, DeMong D, Miller M, Trujillo ME, Kirkland M, Kosinski D, Mane J, Pachanski M, Cheewatrakoolpong B, Di Salvo J, Thomas-Fowlkes B, Souza S, Tatosian DA, Chen Q, Hafey MJ, Houle R, Nolting AF, Orr R, Ehrhart J, Weinglass AB, Tschirret-Guth R, Howard AD, Colletti SL.

ACS Med Chem Lett. 2018 Jun 14;9(7):685-690. doi: 10.1021/acsmedchemlett.8b00149. eCollection 2018 Jul 12.

12.

Defining the Species Micromonospora saelicesensis and Micromonospora noduli Under the Framework of Genomics.

Riesco R, Carro L, Román-Ponce B, Prieto C, Blom J, Klenk HP, Normand P, Trujillo ME.

Front Microbiol. 2018 Jun 25;9:1360. doi: 10.3389/fmicb.2018.01360. eCollection 2018.

13.

Blastococcus atacamensis sp. nov., a novel strain adapted to life in the Yungay core region of the Atacama Desert.

Castro JF, Nouioui I, Sangal V, Choi S, Yang SJ, Kim BY, Trujillo ME, Riesco R, Montero-Calasanz MDC, Rahmani TPD, Bull AT, Sutcliffe IC, Asenjo JA, Andrews B, Goodfellow M.

Int J Syst Evol Microbiol. 2018 Sep;68(9):2712-2721. doi: 10.1099/ijsem.0.002828. Epub 2018 Jul 3.

PMID:
29969090
14.

Geodermatophilus chilensis sp. nov., from soil of the Yungay core-region of the Atacama Desert, Chile.

Castro JF, Nouioui I, Sangal V, Trujillo ME, Montero-Calasanz MDC, Rahmani T, Bull AT, Asenjo JA, Andrews BA, Goodfellow M.

Syst Appl Microbiol. 2018 Sep;41(5):427-436. doi: 10.1016/j.syapm.2018.03.005. Epub 2018 Apr 4.

PMID:
29789182
15.

Avoiding 'salami slicing' in publications describing new prokaryotic taxa.

Trujillo ME, Oren A.

Int J Syst Evol Microbiol. 2018 Apr;68(4):977-978. doi: 10.1099/ijsem.0.002634. Epub 2018 Feb 9. No abstract available.

PMID:
29458506
16.

Proposal of the suffix -ota to denote phyla. Addendum to 'Proposal to include the rank of phylum in the International Code of Nomenclature of Prokaryotes'.

Whitman WB, Oren A, Chuvochina M, da Costa MS, Garrity GM, Rainey FA, Rossello-Mora R, Schink B, Sutcliffe I, Trujillo ME, Ventura S.

Int J Syst Evol Microbiol. 2018 Mar;68(3):967-969. doi: 10.1099/ijsem.0.002593. Epub 2018 Jan 18.

PMID:
29458499
17.

Epidermidibacterium keratini gen. nov., sp. nov., a member of the family Sporichthyaceae, isolated from keratin epidermis.

Lee DG, Trujillo ME, Kang S, Nam JJ, Kim YJ.

Int J Syst Evol Microbiol. 2018 Mar;68(3):745-750. doi: 10.1099/ijsem.0.002579. Epub 2018 Jan 23.

PMID:
29458473
18.

Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.

Feng D, Biftu T, Romero FA, Kekec A, Dropinski J, Kassick A, Xu S, Kurtz MM, Gollapudi A, Shao Q, Yang X, Lu K, Zhou G, Kemp D, Myers RW, Guan HP, Trujillo ME, Li C, Weber A, Sebhat IK.

ACS Med Chem Lett. 2017 Dec 1;9(1):39-44. doi: 10.1021/acsmedchemlett.7b00417. eCollection 2018 Jan 11.

19.

Genome-based classification of micromonosporae with a focus on their biotechnological and ecological potential.

Carro L, Nouioui I, Sangal V, Meier-Kolthoff JP, Trujillo ME, Montero-Calasanz MDC, Sahin N, Smith DL, Kim KE, Peluso P, Deshpande S, Woyke T, Shapiro N, Kyrpides NC, Klenk HP, Göker M, Goodfellow M.

Sci Rep. 2018 Jan 11;8(1):525. doi: 10.1038/s41598-017-17392-0.

20.

Proposed minimal standards for the use of genome data for the taxonomy of prokaryotes.

Chun J, Oren A, Ventosa A, Christensen H, Arahal DR, da Costa MS, Rooney AP, Yi H, Xu XW, De Meyer S, Trujillo ME.

Int J Syst Evol Microbiol. 2018 Jan;68(1):461-466. doi: 10.1099/ijsem.0.002516.

PMID:
29292687
21.

Micromonospora phytophila sp. nov. and Micromonospora luteiviridis sp. nov., isolated as natural inhabitants of plant nodules.

Carro L, Veyisoglu A, Riesco R, Spröer C, Klenk HP, Sahin N, Trujillo ME.

Int J Syst Evol Microbiol. 2018 Jan;68(1):248-253. doi: 10.1099/ijsem.0.002490. Epub 2017 Nov 17.

PMID:
29148367
22.

GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent.

Pachanski MJ, Kirkland ME, Kosinski DT, Mane J, Cheewatrakoolpong B, Xue J, Szeto D, Forrest G, Miller C, Bunzel M, Plummer CW, Chobanian HR, Miller MW, Souza S, Thomas-Fowlkes BS, Ogawa AM, Weinglass AB, Di Salvo J, Li X, Feng Y, Tatosian DA, Howard AD, Colletti SL, Trujillo ME.

PLoS One. 2017 Oct 20;12(10):e0186033. doi: 10.1371/journal.pone.0186033. eCollection 2017.

23.

Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase.

Lan P, Romero FA, Wodka D, Kassick AJ, Dang Q, Gibson T, Cashion D, Zhou G, Chen Y, Zhang X, Zhang A, Li Y, Trujillo ME, Shao Q, Wu M, Xu S, He H, MacKenna D, Staunton J, Chapman KT, Weber A, Sebhat IK, Makara GM.

J Med Chem. 2017 Nov 9;60(21):9040-9052. doi: 10.1021/acs.jmedchem.7b01344. Epub 2017 Oct 25.

PMID:
29035567
24.

Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico.

García-Hernández ME, Cruz-Rivera M, Sánchez-Betancourt JI, Rico-Chávez O, Vergara-Castañeda A, Trujillo ME, Sarmiento-Silva RE.

BMC Vet Res. 2017 Sep 21;13(1):289. doi: 10.1186/s12917-017-1208-z.

25.

Monitoring the colonization and infection of legume nodules by Micromonospora in co-inoculation experiments with rhizobia.

Benito P, Alonso-Vega P, Aguado C, Luján R, Anzai Y, Hirsch AM, Trujillo ME.

Sci Rep. 2017 Sep 8;7(1):11051. doi: 10.1038/s41598-017-11428-1.

26.

Special Issue: the 3rd meeting of the Bergey's International Society for Microbial Systematics (BISMIS).

Hedlund BP, Sutcliffe IC, Trujillo ME.

Antonie Van Leeuwenhoek. 2017 Oct;110(10):1245-1246. doi: 10.1007/s10482-017-0935-2. No abstract available.

PMID:
28840420
27.

Pseudonocardia nigra sp. nov., isolated from Atacama Desert rock.

Trujillo ME, Idris H, Riesco R, Nouioui I, Igual JM, Bull AT, Goodfellow M.

Int J Syst Evol Microbiol. 2017 Aug;67(8):2980-2985. doi: 10.1099/ijsem.0.002063. Epub 2017 Aug 18.

PMID:
28820114
28.

GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production.

Miller C, Pachanski MJ, Kirkland ME, Kosinski DT, Mane J, Bunzel M, Cao J, Souza S, Thomas-Fowlkes B, Di Salvo J, Weinglass AB, Li X, Myers RW, Knagge K, Carrington PE, Hagmann WK, Trujillo ME.

PLoS One. 2017 May 23;12(5):e0176182. doi: 10.1371/journal.pone.0176182. eCollection 2017.

29.

GPR40 reduces food intake and body weight through GLP-1.

Gorski JN, Pachanski MJ, Mane J, Plummer CW, Souza S, Thomas-Fowlkes BS, Ogawa AM, Weinglass AB, Di Salvo J, Cheewatrakoolpong B, Howard AD, Colletti SL, Trujillo ME.

Am J Physiol Endocrinol Metab. 2017 Jul 1;313(1):E37-E47. doi: 10.1152/ajpendo.00435.2016. Epub 2017 Mar 14.

30.

Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus.

Xu J, Lin S, Myers RW, Trujillo ME, Pachanski MJ, Malkani S, Chen HS, Chen Z, Campbell B, Eiermann GJ, Elowe N, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, McMasters DR, Mitra K, Tong X, Xu L, Zhang F, Zhang R, Addona GH, Berger JP, Zhang B, Parmee ER.

Bioorg Med Chem Lett. 2017 May 1;27(9):2063-2068. doi: 10.1016/j.bmcl.2016.10.088. Epub 2016 Oct 31.

PMID:
28284809
31.

Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.

Xu J, Lin S, Myers RW, Addona G, Berger JP, Campbell B, Chen HS, Chen Z, Eiermann GJ, Elowe NH, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, Malkani S, McMasters DR, Mitra K, Pachanski MJ, Tong X, Trujillo ME, Xu L, Zhang B, Zhang F, Zhang R, Parmee ER.

Bioorg Med Chem Lett. 2017 May 1;27(9):2069-2073. doi: 10.1016/j.bmcl.2016.10.085. Epub 2016 Oct 31.

PMID:
28284804
32.

Introducing a Digital Protologue: A timely move towards a database-driven systematics of Archaea and Bacteria.

Rosselló-Móra R, Trujillo ME, Sutcliffe IC.

Syst Appl Microbiol. 2017 Apr;40(3):121-122. doi: 10.1016/j.syapm.2017.02.001. Epub 2017 Feb 17. No abstract available.

PMID:
28249694
33.

Design and Synthesis of Novel, Selective GPR40 AgoPAMs.

Plummer CW, Clements MJ, Chen H, Rajagopalan M, Josien H, Hagmann WK, Miller M, Trujillo ME, Kirkland M, Kosinski D, Mane J, Pachanski M, Cheewatrakoolpong B, Nolting AF, Orr R, Christensen M, Campeau LC, Wright MJ, Bugianesi R, Souza S, Zhang X, Di Salvo J, Weinglass AB, Tschirret-Guth R, Nargund R, Howard AD, Colletti SL.

ACS Med Chem Lett. 2017 Jan 23;8(2):221-226. doi: 10.1021/acsmedchemlett.6b00443. eCollection 2017 Feb 9.

34.

Introducing a digital protologue: a timely move towards a database-driven systematics of archaea and bacteria.

Rosselló-Móra R, Trujillo ME, Sutcliffe IC.

Antonie Van Leeuwenhoek. 2017 Apr;110(4):455-456. doi: 10.1007/s10482-017-0841-7. No abstract available.

PMID:
28168565
35.

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes.

Guo L, Parker DL, Zang Y, Sweis RF, Liu W, Sherer EC, Buist N, Terebetski J, Kelly T, Bugianesi R, Priest BT, Dingley KH, Li X, Mitelman S, Salituro G, Trujillo ME, Pachanski M, Kirkland M, Powles MA, Eiermann GJ, Feng Y, Shang J, Howard AD, Ujjainwalla F, Sinz CJ, Debenham JS, Edmondson SD, Nargund RP, Hagmann WK, Li D.

ACS Med Chem Lett. 2016 Oct 12;7(12):1107-1111. eCollection 2016 Dec 8.

36.

Microbacterium diaminobutyricum sp. nov., isolated from Halimione portulacoides, which contains diaminobutyric acid in its cell wall, and emended description of the genus Microbacterium.

Fidalgo C, Riesco R, Henriques I, Trujillo ME, Alves A.

Int J Syst Evol Microbiol. 2016 Nov;66(11):4492-4500. doi: 10.1099/ijsem.0.001379. Epub 2016 Aug 4.

PMID:
27498827
37.

Micromonospora ureilytica sp. nov., Micromonospora noduli sp. nov. and Micromonospora vinacea sp. nov., isolated from Pisum sativum nodules.

Carro L, Riesco R, Spröer C, Trujillo ME.

Int J Syst Evol Microbiol. 2016 Sep;66(9):3509-3514. doi: 10.1099/ijsem.0.001231. Epub 2016 Jun 8.

PMID:
27282917
38.

Micromonospora luteifusca sp. nov. isolated from cultivated Pisum sativum.

Carro L, Riesco R, Spröer C, Trujillo ME.

Syst Appl Microbiol. 2016 Jun;39(4):237-242. doi: 10.1016/j.syapm.2016.04.003. Epub 2016 May 7.

PMID:
27220477
39.

Modestobacter caceresii sp. nov., novel actinobacteria with an insight into their adaptive mechanisms for survival in extreme hyper-arid Atacama Desert soils.

Busarakam K, Bull AT, Trujillo ME, Riesco R, Sangal V, van Wezel GP, Goodfellow M.

Syst Appl Microbiol. 2016 Jun;39(4):243-251. doi: 10.1016/j.syapm.2016.03.007. Epub 2016 Mar 24.

PMID:
27108251
40.

Description of Kibdelosporangium banguiense sp. nov., a novel actinomycete isolated from soil of the forest of Pama, on the plateau of Bangui, Central African Republic.

Pascual J, González I, Estévez M, Benito P, Trujillo ME, Genilloud O.

Antonie Van Leeuwenhoek. 2016 May;109(5):685-95. doi: 10.1007/s10482-016-0669-6. Epub 2016 Mar 2.

PMID:
26936255
41.

SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists.

He S, Dobbelaar PH, Guo L, Ye Z, Liu J, Jian T, Truong Q, Shah SK, Du W, Qi H, Bakshi RK, Hong Q, Dellureficio JD, Sherer E, Pasternak A, Feng Z, Reibarkh M, Lin M, Samuel K, Reddy VB, Mitelman S, Tong SX, Chicchi GG, Tsao KL, Trusca D, Wu M, Shao Q, Trujillo ME, Fernandez G, Nelson D, Bunting P, Kerr J, Fitzgerald P, Morissette P, Volksdorf S, Eiermann GJ, Li C, Zhang BB, Howard AD, Zhou YP, Nargund RP, Hagmann WK.

Bioorg Med Chem Lett. 2016 Mar 15;26(6):1529-1535. doi: 10.1016/j.bmcl.2016.02.022. Epub 2016 Feb 10.

PMID:
26898814
42.

Proposal to include the rank of phylum in the International Code of Nomenclature of Prokaryotes.

Oren A, da Costa MS, Garrity GM, Rainey FA, Rosselló-Móra R, Schink B, Sutcliffe I, Trujillo ME, Whitman WB.

Int J Syst Evol Microbiol. 2015 Nov;65(11):4284-4287. doi: 10.1099/ijsem.0.000664.

PMID:
26654112
43.

Endophytic Actinobacteria and the Interaction of Micromonospora and Nitrogen Fixing Plants.

Trujillo ME, Riesco R, Benito P, Carro L.

Front Microbiol. 2015 Dec 1;6:1341. doi: 10.3389/fmicb.2015.01341. eCollection 2015. Review.

44.

Arthroamide, a Cyclic Depsipeptide with Quorum Sensing Inhibitory Activity from Arthrobacter sp.

Igarashi Y, Yamamoto K, Fukuda T, Shojima A, Nakayama J, Carro L, Trujillo ME.

J Nat Prod. 2015 Nov 25;78(11):2827-31. doi: 10.1021/acs.jnatprod.5b00540. Epub 2015 Nov 17.

PMID:
26575343
45.

Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes.

Shah SK, He S, Guo L, Truong Q, Qi H, Du W, Lai Z, Liu J, Jian T, Hong Q, Dobbelaar P, Ye Z, Sherer E, Feng Z, Yu Y, Wong F, Samuel K, Madiera M, Karanam BV, Reddy VB, Mitelman S, Tong SX, Chicchi GG, Tsao KL, Trusca D, Feng Y, Wu M, Shao Q, Trujillo ME, Eiermann GJ, Li C, Pachanski M, Fernandez G, Nelson D, Bunting P, Morissette P, Volksdorf S, Kerr J, Zhang BB, Howard AD, Zhou YP, Pasternak A, Nargund RP, Hagmann WK.

ACS Med Chem Lett. 2015 Mar 18;6(5):513-7. doi: 10.1021/ml500514w. eCollection 2015 May 14.

46.

Modestobacter lapidis sp. nov. and Modestobacter muralis sp. nov., isolated from a deteriorated sandstone historic building in Salamanca, Spain.

Trujillo ME, Goodfellow M, Busarakam K, Riesco R.

Antonie Van Leeuwenhoek. 2015 Aug;108(2):311-20. doi: 10.1007/s10482-015-0482-7. Epub 2015 May 19.

PMID:
25987397
47.

Microbacterium proteolyticum sp. nov. isolated from roots of Halimione portulacoides.

Alves A, Riesco R, Correia A, Trujillo ME.

Int J Syst Evol Microbiol. 2015 Jun;65(Pt 6):1794-8. doi: 10.1099/ijs.0.000177. Epub 2015 Mar 5.

PMID:
25744585
48.

GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo.

Hauge M, Vestmar MA, Husted AS, Ekberg JP, Wright MJ, Di Salvo J, Weinglass AB, Engelstoft MS, Madsen AN, Lückmann M, Miller MW, Trujillo ME, Frimurer TM, Holst B, Howard AD, Schwartz TW.

Mol Metab. 2014 Oct 24;4(1):3-14. doi: 10.1016/j.molmet.2014.10.002. eCollection 2015 Jan.

49.

CORRIGENDUM: Micromonospora from nitrogen fixing nodules of alfalfa (Medicago sativa L.). A new promising Plant Probiotic Bacteria.

Martínez-Hidalgo P, Galindo-Villardón P, Trujillo ME, Igual JM, Martínez-Molina E.

Sci Rep. 2015 Feb 11;5:8271. doi: 10.1038/srep08271. No abstract available.

50.

Revision of the taxonomic status of the species Rhizobium lupini and reclassification as Bradyrhizobium lupini comb. nov.

Peix A, Ramírez-Bahena MH, Flores-Félix JD, Alonso de la Vega P, Rivas R, Mateos PF, Igual JM, Martínez-Molina E, Trujillo ME, Velázquez E.

Int J Syst Evol Microbiol. 2015 Apr;65(Pt 4):1213-9. doi: 10.1099/ijs.0.000082. Epub 2015 Jan 21.

PMID:
25609676

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