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Items: 8


Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing.

Khoo SK, Read J, Franks K, Zhang G, Bizzintino J, Coleman L, McCrae C, Öberg L, Troy NM, Prastanti F, Everard J, Oo S, Borland ML, Maciewicz RA, Le Souëf PN, Laing IA, Bosco A.

J Immunol. 2019 Mar 15;202(6):1845-1858. doi: 10.4049/jimmunol.1800178. Epub 2019 Feb 11.


Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics.

Jones AC, Troy NM, White E, Hollams EM, Gout AM, Ling KM, Kicic A, Stick SM, Sly PD, Holt PG, Hall GL, Bosco A.

Sci Rep. 2018 Jan 24;8(1):1511. doi: 10.1038/s41598-018-19837-6.


Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16.

Xi Y, Troy NM, Anderson D, Pena OM, Lynch JP, Phipps S, Bosco A, Upham JW.

Front Immunol. 2017 Oct 25;8:1351. doi: 10.3389/fimmu.2017.01351. eCollection 2017.


Respiratory viral infections and host responses; insights from genomics.

Troy NM, Bosco A.

Respir Res. 2016 Nov 21;17(1):156. Review.


Protection against maternal infection-associated fetal growth restriction: proof-of-concept with a microbial-derived immunomodulator.

Scott NM, Lauzon-Joset JF, Jones AC, Mincham KT, Troy NM, Leffler J, Serralha M, Prescott SL, Robertson SA, Pasquali C, Bosco A, Holt PG, Strickland DH.

Mucosal Immunol. 2017 May;10(3):789-801. doi: 10.1038/mi.2016.85. Epub 2016 Oct 19.


Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.

Looi K, Troy NM, Garratt LW, Iosifidis T, Bosco A, Buckley AG, Ling KM, Martinovich KM, Kicic-Starcevich E, Shaw NC, Sutanto EN, Zosky GR, Rigby PJ, Larcombe AN, Knight DA, Kicic A, Stick SM.

Exp Lung Res. 2016 Oct 11:1-16. [Epub ahead of print]


Identification of genes differentially regulated by vitamin D deficiency that alter lung pathophysiology and inflammation in allergic airways disease.

Foong RE, Bosco A, Troy NM, Gorman S, Hart PH, Kicic A, Zosky GR.

Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L653-63. doi: 10.1152/ajplung.00026.2016. Epub 2016 Aug 5.


Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses.

Troy NM, Hollams EM, Holt PG, Bosco A.

BMC Med Genomics. 2016 Feb 27;9:9. doi: 10.1186/s12920-016-0171-z.

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