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Items: 1 to 50 of 416

1.

Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1.

Boelen L, Debebe B, Silveira M, Salam A, Makinde J, Roberts CH, Wang ECY, Frater J, Gilmour J, Twigger K, Ladell K, Miners KL, Jayaraman J, Traherne JA, Price DA, Qi Y, Martin MP, Macallan DC, Thio CL, Astemborski J, Kirk G, Donfield SM, Buchbinder S, Khakoo SI, Goedert JJ, Trowsdale J, Carrington M, Kollnberger S, Asquith B.

Sci Immunol. 2018 Nov 9;3(29). pii: eaao2892. doi: 10.1126/sciimmunol.aao2892.

PMID:
30413420
2.

Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop.

Misra MK, Augusto DG, Martin GM, Nemat-Gorgani N, Sauter J, Hofmann JA, Traherne JA, González-Quezada B, Gorodezky C, Bultitude WP, Marin W, Vierra-Green C, Anderson KM, Balas A, Caro-Oleas JL, Cisneros E, Colucci F, Dandekar R, Elfishawi SM, Fernández-Viña MA, Fouda M, González-Fernández R, Große A, Herrero-Mata MJ, Hollenbach SQ, Marsh SGE, Mentzer A, Middleton D, Moffett A, Moreno-Hidalgo MA, Mossallam GI, Nakimuli A, Oksenberg JR, Oppenheimer SJ, Parham P, Petzl-Erler ML, Planelles D, Sánchez-García F, Sánchez-Gordo F, Schmidt AH, Trowsdale J, Vargas LB, Vicario JL, Vilches C, Norman PJ, Hollenbach JA.

Hum Immunol. 2018 Dec;79(12):825-833. doi: 10.1016/j.humimm.2018.10.003. Epub 2018 Oct 12. Review.

PMID:
30321631
3.

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia.

Huhn O, Chazara O, Ivarsson MA, Retière C, Venkatesan TC, Norman PJ, Hilton HG, Jayaraman J, Traherne JA, Trowsdale J, Ito M, Kling C, Parham P, Ghadially H, Moffett A, Sharkey AM, Colucci F.

J Immunol. 2018 Nov 1;201(9):2593-2601. doi: 10.4049/jimmunol.1800860. Epub 2018 Sep 24.

PMID:
30249807
4.

Genetics of antigen processing and presentation.

Kelly A, Trowsdale J.

Immunogenetics. 2018 Sep 13. doi: 10.1007/s00251-018-1082-2. [Epub ahead of print] Review.

PMID:
30215098
5.

Regulation of Human γδ T Cells by BTN3A1 Protein Stability and ATP-Binding Cassette Transporters.

Rhodes DA, Chen HC, Williamson JC, Hill A, Yuan J, Smith S, Rhodes H, Trowsdale J, Lehner PJ, Herrmann T, Eberl M.

Front Immunol. 2018 Apr 4;9:662. doi: 10.3389/fimmu.2018.00662. eCollection 2018.

6.

Novel KIR genotypes and gene copy number variations in northeastern Thais.

Chaisri S, Traherne JA, Jayaraman J, Romphruk A, Trowsdale J, Leelayuwat C.

Immunology. 2018 Mar;153(3):380-386. doi: 10.1111/imm.12847. Epub 2017 Oct 23.

PMID:
28950036
7.

Introduction: MHC/KIR and governance of specificity.

Kelly A, Trowsdale J.

Immunogenetics. 2017 Aug;69(8-9):481-488. doi: 10.1007/s00251-017-0986-6. Epub 2017 Jul 10. Review.

8.

Modulation of Human Leukocyte Antigen-C by Human Cytomegalovirus Stimulates KIR2DS1 Recognition by Natural Killer Cells.

van der Ploeg K, Chang C, Ivarsson MA, Moffett A, Wills MR, Trowsdale J.

Front Immunol. 2017 Mar 29;8:298. doi: 10.3389/fimmu.2017.00298. eCollection 2017.

9.

Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation.

Fielding CA, Weekes MP, Nobre LV, Ruckova E, Wilkie GS, Paulo JA, Chang C, Suárez NM, Davies JA, Antrobus R, Stanton RJ, Aicheler RJ, Nichols H, Vojtesek B, Trowsdale J, Davison AJ, Gygi SP, Tomasec P, Lehner PJ, Wilkinson GW.

Elife. 2017 Feb 10;6. pii: e22206. doi: 10.7554/eLife.22206.

10.

T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System.

Huang WC, Easom NJ, Tang XZ, Gill US, Singh H, Robertson F, Chang C, Trowsdale J, Davidson BR, Rosenberg WM, Fusai G, Toubert A, Kennedy PT, Peppa D, Maini MK.

J Immunol. 2017 Feb 1;198(3):1172-1182. doi: 10.4049/jimmunol.1601313. Epub 2016 Dec 28.

11.

Estimating KIR Haplotype Frequencies on a Cohort of 10,000 Individuals: A Comprehensive Study on Population Variations, Typing Resolutions, and Reference Haplotypes.

Vierra-Green C, Roe D, Jayaraman J, Trowsdale J, Traherne J, Kuang R, Spellman S, Maiers M.

PLoS One. 2016 Oct 10;11(10):e0163973. doi: 10.1371/journal.pone.0163973. eCollection 2016.

12.

qKAT: a high-throughput qPCR method for KIR gene copy number and haplotype determination.

Jiang W, Johnson C, Simecek N, López-Álvarez MR, Di D, Trowsdale J, Traherne JA.

Genome Med. 2016 Sep 29;8(1):99.

13.

Host response: Sensing microbial sabotage.

Trowsdale J.

Nat Microbiol. 2016 May 26;1(6):16071. doi: 10.1038/nmicrobiol.2016.71. No abstract available.

PMID:
27572843
14.

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.

Norman PJ, Hollenbach JA, Nemat-Gorgani N, Marin WM, Norberg SJ, Ashouri E, Jayaraman J, Wroblewski EE, Trowsdale J, Rajalingam R, Oksenberg JR, Chiaroni J, Guethlein LA, Traherne JA, Ronaghi M, Parham P.

Am J Hum Genet. 2016 Aug 4;99(2):375-91. doi: 10.1016/j.ajhg.2016.06.023.

15.

LILRA6 copy number variation correlates with susceptibility to atopic dermatitis.

López-Álvarez MR, Jiang W, Jones DC, Jayaraman J, Johnson C, Cookson WO, Moffatt MF, Trowsdale J, Traherne JA.

Immunogenetics. 2016 Oct;68(9):743-7. doi: 10.1007/s00251-016-0924-z. Epub 2016 Jun 22.

16.

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.

Liu LL, Landskron J, Ask EH, Enqvist M, Sohlberg E, Traherne JA, Hammer Q, Goodridge JP, Larsson S, Jayaraman J, Oei VYS, Schaffer M, Taskén K, Ljunggren HG, Romagnani C, Trowsdale J, Malmberg KJ, Béziat V.

Cell Rep. 2016 May 3;15(5):1088-1099. doi: 10.1016/j.celrep.2016.04.005. Epub 2016 Apr 21.

17.

Interaction of the LILRB1 inhibitory receptor with HLA class Ia dimers.

Baía D, Pou J, Jones D, Mandelboim O, Trowsdale J, Muntasell A, López-Botet M.

Eur J Immunol. 2016 Jul;46(7):1681-90. doi: 10.1002/eji.201546149. Epub 2016 Jun 2.

18.

STAT4-associated natural killer cell tolerance following liver transplantation.

Jamil KM, Hydes TJ, Cheent KS, Cassidy SA, Traherne JA, Jayaraman J, Trowsdale J, Alexander GJ, Little AM, McFarlane H, Heneghan MA, Purbhoo MA, Khakoo SI.

Gut. 2017 Feb;66(2):352-361. doi: 10.1136/gutjnl-2015-309395. Epub 2016 Feb 17.

19.

Regulation of Immunity by Butyrophilins.

Rhodes DA, Reith W, Trowsdale J.

Annu Rev Immunol. 2016 May 20;34:151-72. doi: 10.1146/annurev-immunol-041015-055435. Epub 2016 Jan 11. Review.

PMID:
26772212
20.

Allele-specific recognition by LILRB3 and LILRA6 of a cytokeratin 8-associated ligand on necrotic glandular epithelial cells.

Jones DC, Hewitt CR, López-Álvarez MR, Jahnke M, Russell AI, Radjabova V, Trowsdale AR, Trowsdale J.

Oncotarget. 2016 Mar 29;7(13):15618-31. doi: 10.18632/oncotarget.6905.

21.

KIR haplotypes are associated with late-onset type 1 diabetes in European-American families.

Traherne JA, Jiang W, Valdes AM, Hollenbach JA, Jayaraman J, Lane JA, Johnson C, Trowsdale J, Noble JA.

Genes Immun. 2016 Jan-Feb;17(1):8-12. doi: 10.1038/gene.2015.44. Epub 2015 Oct 22.

22.

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst.

Hermann C, van Hateren A, Trautwein N, Neerincx A, Duriez PJ, Stevanović S, Trowsdale J, Deane JE, Elliott T, Boyle LH.

Elife. 2015 Oct 6;4. pii: e09617. doi: 10.7554/eLife.09617.

23.

Imputation of KIR Types from SNP Variation Data.

Vukcevic D, Traherne JA, Næss S, Ellinghaus E, Kamatani Y, Dilthey A, Lathrop M, Karlsen TH, Franke A, Moffatt M, Cookson W, Trowsdale J, McVean G, Sawcer S, Leslie S.

Am J Hum Genet. 2015 Oct 1;97(4):593-607. doi: 10.1016/j.ajhg.2015.09.005.

24.

The interaction of genetic determinants in the outcome of HCV infection: evidence for discrete immunological pathways.

Hydes TJ, Moesker B, Traherne JA, Ashraf S, Alexander GJ, Dimitrov BD, Woelk CH, Trowsdale J, Khakoo SI.

Tissue Antigens. 2015 Oct;86(4):267-75. doi: 10.1111/tan.12650.

25.

TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils.

Radjabova V, Mastroeni P, Skjødt K, Zaccone P, de Bono B, Goodall JC, Chilvers ER, Juss JK, Jones DC, Trowsdale J, Barrow AD.

J Immunol. 2015 Oct 1;195(7):3149-59. doi: 10.4049/jimmunol.1401847. Epub 2015 Aug 26.

26.

Surveillance of cell and tissue perturbation by receptors in the LRC.

Trowsdale J, Jones DC, Barrow AD, Traherne JA.

Immunol Rev. 2015 Sep;267(1):117-36. doi: 10.1111/imr.12314. Review.

PMID:
26284474
27.

2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.

Dunphy SE, Guinan KJ, Chorcora CN, Jayaraman J, Traherne JA, Trowsdale J, Pende D, Middleton D, Gardiner CM.

Genes Immun. 2015 Jul-Aug;16(5):301-10. doi: 10.1038/gene.2015.15. Epub 2015 May 7.

PMID:
25950617
28.

TAPBPR: a new player in the MHC class I presentation pathway.

Hermann C, Trowsdale J, Boyle LH.

Tissue Antigens. 2015 Mar;85(3):155-66. doi: 10.1111/tan.12538. Review.

PMID:
25720504
29.

Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin.

Rhodes DA, Chen HC, Price AJ, Keeble AH, Davey MS, James LC, Eberl M, Trowsdale J.

J Immunol. 2015 Mar 1;194(5):2390-8. doi: 10.4049/jimmunol.1401064. Epub 2015 Jan 30.

30.

A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia.

Nakimuli A, Chazara O, Hiby SE, Farrell L, Tukwasibwe S, Jayaraman J, Traherne JA, Trowsdale J, Colucci F, Lougee E, Vaughan RW, Elliott AM, Byamugisha J, Kaleebu P, Mirembe F, Nemat-Gorgani N, Parham P, Norman PJ, Moffett A.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):845-50. doi: 10.1073/pnas.1413453112. Epub 2015 Jan 5.

31.

Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.

Jones DC, Peacock S, Hughes D, Traherne JA, Allen RL, Barnardo MC, Friend P, Taylor CJ, Fuggle S, Trowsdale J, Young NT.

Genes Immun. 2014 Dec;15(8):562-8. doi: 10.1038/gene.2014.53. Epub 2014 Sep 25.

PMID:
25253288
32.

Medawar and the immunological paradox of pregnancy: 60 years on.

Colucci F, Moffett A, Trowsdale J.

Eur J Immunol. 2014 Jul;44(7):1883-5. doi: 10.1002/eji.201470065. No abstract available.

33.

Reply to Ding et al.: Non-Neanderthal origin of the HLA-DPB1*0401.

Trowsdale J, Koch N.

J Biol Chem. 2014 Apr 4;289(14):10253. No abstract available.

34.

HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation.

Fosby B, Næss S, Hov JR, Traherne J, Boberg KM, Trowsdale J, Foss A, Line PD, Franke A, Melum E, Scott H, Karlsen TH.

World J Gastroenterol. 2014 Apr 14;20(14):3986-4000. doi: 10.3748/wjg.v20.i14.3986.

35.

Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation.

Béziat V, Traherne J, Malmberg JA, Ivarsson MA, Björkström NK, Retière C, Ljunggren HG, Michaëlsson J, Trowsdale J, Malmberg KJ.

Eur J Immunol. 2014 Jul;44(7):2192-6. doi: 10.1002/eji.201444464. Epub 2014 May 7. No abstract available.

36.

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.

Pontikos N, Smyth DJ, Schuilenburg H, Howson JM, Walker NM, Burren OS, Guo H, Onengut-Gumuscu S, Chen WM, Concannon P, Rich SS, Jayaraman J, Jiang W, Traherne JA, Trowsdale J, Todd JA, Wallace C.

BMC Genomics. 2014 Apr 11;15:274. doi: 10.1186/1471-2164-15-274.

37.

LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.

Bashirova AA, Martin-Gayo E, Jones DC, Qi Y, Apps R, Gao X, Burke PS, Taylor CJ, Rogich J, Wolinsky S, Bream JH, Duggal P, Hussain S, Martinson J, Weintrob A, Kirk GD, Fellay J, Buchbinder SP, Goedert JJ, Deeks SG, Pereyra F, Trowsdale J, Lichterfeld M, Telenti A, Walker BD, Allen RL, Carrington M, Yu XG.

PLoS Genet. 2014 Mar 6;10(3):e1004196. doi: 10.1371/journal.pgen.1004196. eCollection 2014 Mar.

38.

Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR.

Roberts CH, Jiang W, Jayaraman J, Trowsdale J, Holland MJ, Traherne JA.

Genome Med. 2014 Mar 5;6(3):20. doi: 10.1186/gm537. eCollection 2014.

39.

Development and use of IgM/J-chain fusion proteins for characterization of immunoglobulin superfamily ligand-receptor interactions.

Ammann JU, Trowsdale J.

Curr Protoc Protein Sci. 2014 Feb 3;75:Unit 19.24.. doi: 10.1002/0471140864.ps1924s75.

PMID:
24510674
40.

Recognition of Salmonella by Dectin-1 induces presentation of peptide antigen to type B T cells.

Jackson N, Compton E, Trowsdale J, Kelly AP.

Eur J Immunol. 2014 Apr;44(4):962-9. doi: 10.1002/eji.201344065. Epub 2014 Feb 16.

41.

Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors.

López-Álvarez MR, Jones DC, Jiang W, Traherne JA, Trowsdale J.

Immunogenetics. 2014 Feb;66(2):73-83. doi: 10.1007/s00251-013-0742-5. Epub 2013 Nov 21.

42.

A novel family of human leukocyte antigen class II receptors may have its origin in archaic human species.

Temme S, Zacharias M, Neumann J, Wohlfromm S, König A, Temme N, Springer S, Trowsdale J, Koch N.

J Biol Chem. 2014 Jan 10;289(2):639-53. doi: 10.1074/jbc.M113.515767. Epub 2013 Nov 8.

43.

Major histocompatibility complex genomics and human disease.

Trowsdale J, Knight JC.

Annu Rev Genomics Hum Genet. 2013;14:301-23. doi: 10.1146/annurev-genom-091212-153455. Epub 2013 Jul 15. Review.

44.

Influence of KIR gene copy number on natural killer cell education.

Béziat V, Traherne JA, Liu LL, Jayaraman J, Enqvist M, Larsson S, Trowsdale J, Malmberg KJ.

Blood. 2013 Jun 6;121(23):4703-7. doi: 10.1182/blood-2012-10-461442. Epub 2013 May 1.

45.

Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes.

Ammann JU, Cooke A, Trowsdale J.

J Immunol. 2013 May 15;190(10):5030-6. doi: 10.4049/jimmunol.1203325. Epub 2013 Apr 15.

46.

Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway.

Boyle LH, Hermann C, Boname JM, Porter KM, Patel PA, Burr ML, Duncan LM, Harbour ME, Rhodes DA, Skjødt K, Lehner PJ, Trowsdale J.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3465-70. doi: 10.1073/pnas.1222342110. Epub 2013 Feb 11.

47.

Ubiquitination of HLA-DO by MARCH family E3 ligases.

Jahnke M, Trowsdale J, Kelly AP.

Eur J Immunol. 2013 May;43(5):1153-61. doi: 10.1002/eji.201243043. Epub 2013 Mar 11.

48.

HLA reduces killer cell Ig-like receptor expression level and frequency in a humanized mouse model.

van Bergen J, Thompson A, van Pel M, Retière C, Salvatori D, Raulet DH, Trowsdale J, Koning F.

J Immunol. 2013 Mar 15;190(6):2880-5. doi: 10.4049/jimmunol.1200650. Epub 2013 Feb 6.

49.

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs.

Béziat V, Liu LL, Malmberg JA, Ivarsson MA, Sohlberg E, Björklund AT, Retière C, Sverremark-Ekström E, Traherne J, Ljungman P, Schaffer M, Price DA, Trowsdale J, Michaëlsson J, Ljunggren HG, Malmberg KJ.

Blood. 2013 Apr 4;121(14):2678-88. doi: 10.1182/blood-2012-10-459545. Epub 2013 Jan 16.

50.

Salmonella polarises peptide-MHC-II presentation towards an unconventional Type B CD4+ T-cell response.

Jackson NP, Kang YH, Lapaque N, Janssen H, Trowsdale J, Kelly AP.

Eur J Immunol. 2013 Apr;43(4):897-906. doi: 10.1002/eji.201242983. Epub 2013 Feb 18.

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