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Items: 24


The BCGΔBCG1419c Vaccine Candidate Reduces Lung Pathology, IL-6, TNF-α, and IL-10 During Chronic TB Infection.

Flores-Valdez MA, Pedroza-Roldán C, Aceves-Sánchez MJ, Peterson EJR, Baliga NS, Hernández-Pando R, Troudt J, Creissen E, Izzo L, Bielefeldt-Ohmann H, Bickett T, Izzo AA.

Front Microbiol. 2018 Jun 12;9:1281. doi: 10.3389/fmicb.2018.01281. eCollection 2018.


Mycobacterium tuberculosis sigE mutant ST28 used as a vaccine induces protective immunity in the guinea pig model.

Troudt J, Creissen E, Izzo L, Bielefeldt-Ohmann H, Casonato S, Manganelli R, Izzo AA.

Tuberculosis (Edinb). 2017 Sep;106:99-105. doi: 10.1016/ Epub 2017 Jul 24.


Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion.

Duncan C, Jamieson FB, Troudt J, Izzo L, Bielefeldt-Ohmann H, Izzo A, Mehaffy C.

PLoS One. 2017 Jun 26;12(6):e0179996. doi: 10.1371/journal.pone.0179996. eCollection 2017.


Humanized NOG mice as a model for tuberculosis vaccine-induced immunity: a comparative analysis with the mouse and guinea pig models of tuberculosis.

Grover A, Troy A, Rowe J, Troudt JM, Creissen E, McLean J, Banerjee P, Feuer G, Izzo AA.

Immunology. 2017 Sep;152(1):150-162. doi: 10.1111/imm.12756. Epub 2017 Jun 19.


Virulence of Mycobacterium tuberculosis after Acquisition of Isoniazid Resistance: Individual Nature of katG Mutants and the Possible Role of AhpC.

Nieto R LM, Mehaffy C, Creissen E, Troudt J, Troy A, Bielefeldt-Ohmann H, Burgos M, Izzo A, Dobos KM.

PLoS One. 2016 Nov 28;11(11):e0166807. doi: 10.1371/journal.pone.0166807. eCollection 2016.


Heat killed Saccharomyces cerevisiae as an adjuvant for the induction of vaccine-mediated immunity against infection with Mycobacterium tuberculosis.

Grover A, McLean JL, Troudt JM, Foster C, Izzo L, Creissen E, MacDonald E, Troy A, Izzo AA.

Vaccine. 2016 May 27;34(25):2798-805. doi: 10.1016/j.vaccine.2016.04.052. Epub 2016 Apr 28.


Isolation and purification of Mycobacterium tuberculosis from H37Rv infected guinea pig lungs.

Shi L, Ryan GJ, Bhamidi S, Troudt J, Amin A, Izzo A, Lenaerts AJ, McNeil MR, Belisle JT, Crick DC, Chatterjee D.

Tuberculosis (Edinb). 2014 Sep;94(5):525-30. doi: 10.1016/ Epub 2014 Jun 30.


HspX vaccination and role in virulence in the guinea pig model of tuberculosis.

Wieczorek AE, Troudt JL, Knabenbauer P, Taylor J, Pavlicek RL, Karls R, Hess A, Davidson RM, Strong M, Bielefeldt-Ohmann H, Izzo AA, Dobos KM.

Pathog Dis. 2014 Aug;71(3):315-25. doi: 10.1111/2049-632X.12147. Epub 2014 Feb 24.


High mobility group box 1 acts as an adjuvant for tuberculosis subunit vaccines.

Grover A, Troudt J, Foster C, Basaraba R, Izzo A.

Immunology. 2014 May;142(1):111-23. doi: 10.1111/imm.12236.


BCG sub-strains induce variable protection against virulent pulmonary Mycobacterium tuberculosis infection, with the capacity to drive Th2 immunity.

Keyser A, Troudt JM, Taylor JL, Izzo AA.

Vaccine. 2011 Nov 21;29(50):9308-15. doi: 10.1016/j.vaccine.2011.10.019. Epub 2011 Oct 18.


Recombinant adenovirus delivery of calreticulin-ESAT-6 produces an antigen-specific immune response but no protection against a Mycobacterium tuberculosis challenge.

Esparza-González SC, Troy A, Troudt J, Loera-Arias MJ, Villatoro-Hernández J, Torres-López E, Ancer-Rodríguez J, Gutiérrez-Puente Y, Muñoz-Maldonado G, Saucedo-Cárdenas O, Montes-de-Oca-Luna R, Izzo A.

Scand J Immunol. 2012 Mar;75(3):259-65. doi: 10.1111/j.1365-3083.2011.02655.x.


Assessment of vaccine testing at three laboratories using the guinea pig model of tuberculosis.

Grover A, Troudt J, Arnett K, Izzo L, Lucas M, Strain K, McFarland C, Hall Y, McMurray D, Williams A, Dobos K, Izzo A.

Tuberculosis (Edinb). 2012 Jan;92(1):105-11. doi: 10.1016/ Epub 2011 Oct 1.


Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: ex vivo 1H magic angle spinning NMR studies.

Somashekar BS, Amin AG, Rithner CD, Troudt J, Basaraba R, Izzo A, Crick DC, Chatterjee D.

J Proteome Res. 2011 Sep 2;10(9):4186-95. doi: 10.1021/pr2003352. Epub 2011 Jul 26.


Three protein cocktails mediate delayed-type hypersensitivity responses indistinguishable from that elicited by purified protein derivative in the guinea pig model of Mycobacterium tuberculosis infection.

Yang H, Troudt J, Grover A, Arnett K, Lucas M, Cho YS, Bielefeldt-Ohmann H, Taylor J, Izzo A, Dobos KM.

Infect Immun. 2011 Feb;79(2):716-23. doi: 10.1128/IAI.00486-10. Epub 2010 Dec 6.


Portrait of a pathogen: the Mycobacterium tuberculosis proteome in vivo.

Kruh NA, Troudt J, Izzo A, Prenni J, Dobos KM.

PLoS One. 2010 Nov 11;5(11):e13938. doi: 10.1371/journal.pone.0013938.


Initiation of acquired immunity in the lungs of mice lacking lymph nodes after infection with aerosolized Mycobacterium tuberculosis.

Kashino SS, Vallerskog T, Martens G, Troudt J, Keyser A, Taylor J, Izzo A, Kornfeld H, Campos-Neto A.

Am J Pathol. 2010 Jan;176(1):198-204. doi: 10.2353/ajpath.2010.090446. Epub 2009 Dec 11.


Kinetics of the immune response profile in guinea pigs after vaccination with Mycobacterium bovis BCG and infection with Mycobacterium tuberculosis.

Grover A, Taylor J, Troudt J, Keyser A, Arnett K, Izzo L, Rholl D, Izzo A.

Infect Immun. 2009 Nov;77(11):4837-46. doi: 10.1128/IAI.00704-09. Epub 2009 Sep 8.


Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen dose.

Aagaard C, Hoang TT, Izzo A, Billeskov R, Troudt J, Arnett K, Keyser A, Elvang T, Andersen P, Dietrich J.

PLoS One. 2009 Jun 16;4(6):e5930. doi: 10.1371/journal.pone.0005930.


Immune response induced by three Mycobacterium bovis BCG substrains with diverse regions of deletion in a C57BL/6 mouse model.

Irwin SM, Goodyear A, Keyser A, Christensen R, Troudt JM, Taylor JL, Bohsali A, Briken V, Izzo AA.

Clin Vaccine Immunol. 2008 May;15(5):750-6. doi: 10.1128/CVI.00018-08. Epub 2008 Mar 19.


Mycobacterial infection induces the secretion of high-mobility group box 1 protein.

Grover A, Taylor J, Troudt J, Keyser A, Sommersted K, Schenkel A, Izzo AA.

Cell Microbiol. 2008 Jun;10(6):1390-404. doi: 10.1111/j.1462-5822.2008.01135.x. Epub 2008 Mar 5.


Animal model of Mycobacterium abscessus lung infection.

Ordway D, Henao-Tamayo M, Smith E, Shanley C, Harton M, Troudt J, Bai X, Basaraba RJ, Orme IM, Chan ED.

J Leukoc Biol. 2008 Jun;83(6):1502-11. doi: 10.1189/jlb.1007696. Epub 2008 Feb 29.


The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation.

Ordway D, Henao-Tamayo M, Harton M, Palanisamy G, Troudt J, Shanley C, Basaraba RJ, Orme IM.

J Immunol. 2007 Jul 1;179(1):522-31.


Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium tuberculosis infection.

Taylor JL, Hattle JM, Dreitz SA, Troudt JM, Izzo LS, Basaraba RJ, Orme IM, Matrisian LM, Izzo AA.

Infect Immun. 2006 Nov;74(11):6135-44. Epub 2006 Sep 18.


Factors associated with severe granulomatous pneumonia in Mycobacterium tuberculosis-infected mice vaccinated therapeutically with hsp65 DNA.

Taylor JL, Ordway DJ, Troudt J, Gonzalez-Juarrero M, Basaraba RJ, Orme IM.

Infect Immun. 2005 Aug;73(8):5189-93.

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