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Items: 1 to 50 of 132

1.

BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS.

Röck R, Mayrhofer JE, Torres-Quesada O, Enzler F, Raffeiner A, Raffeiner P, Feichtner A, Huber RG, Koide S, Taylor SS, Troppmair J, Stefan E.

Sci Adv. 2019 Aug 14;5(8):eaav8463. doi: 10.1126/sciadv.aav8463. eCollection 2019 Aug.

2.

The Human G Protein-Coupled ATP Receptor P2Y11 Is Associated With IL-10 Driven Macrophage Differentiation.

Gruenbacher G, Gander H, Rahm A, Dobler G, Drasche A, Troppmair J, Nussbaumer W, Thurnher M.

Front Immunol. 2019 Aug 9;10:1870. doi: 10.3389/fimmu.2019.01870. eCollection 2019.

3.

PREOPERATIVE ASSESSMENT OF MUSCLE MASS USING COMPUTERIZED TOMOGRAPHY SCANS TO PREDICT OUTCOMES FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION.

Esser H, Resch T, Pamminger M, Mutschlechner B, Troppmair J, Riedmann M, Gassner E, Maglione M, Margreiter C, Boesmueller C, Oberhuber R, Weissenbacher A, Cardini B, Finkenstedt A, Zoller H, Tilg H, Öfner D, Schneeberger S.

Transplantation. 2019 Apr 10. doi: 10.1097/TP.0000000000002759. [Epub ahead of print]

PMID:
30985737
4.

Associations of Oxidative Stress and Postoperative Outcome in Liver Surgery with an Outlook to Future Potential Therapeutic Options.

Senoner T, Schindler S, Stättner S, Öfner D, Troppmair J, Primavesi F.

Oxid Med Cell Longev. 2019 Feb 13;2019:3950818. doi: 10.1155/2019/3950818. eCollection 2019. Review.

5.

Subcutaneous administration of a neutralizing IL-1β antibody prolongs limb allograft survival.

Hautz T, Grahammer J, Moser D, Eberhart N, Zelger B, Zelger B, Blumer MJ, Drasche A, Wolfram D, Troppmair J, Öfner D, Schneeberger S.

Am J Transplant. 2018 Aug;18(8):2029-2042. doi: 10.1111/ajt.14765. Epub 2018 May 7.

6.

The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells.

Furlan T, Khalid S, Nguyen AV, Günther J, Troppmair J.

Mol Oncol. 2018 Jun;12(6):869-882. doi: 10.1002/1878-0261.12199. Epub 2018 May 5.

7.

Development of an in vitro potency assay for human skeletal muscle derived cells.

Thurner M, Asim F, Garczarczyk-Asim D, Janke K, Deutsch M, Margreiter E, Troppmair J, Marksteiner R.

PLoS One. 2018 Mar 22;13(3):e0194561. doi: 10.1371/journal.pone.0194561. eCollection 2018.

8.

Targeting the Architecture of Deregulated Protein Complexes in Cancer.

Stefan E, Troppmair J, Bister K.

Adv Protein Chem Struct Biol. 2018;111:101-132. doi: 10.1016/bs.apcsb.2017.07.001. Epub 2017 Aug 18. Review.

PMID:
29459029
9.

Calcineurin inhibitor-induced complement system activation via ERK1/2 signalling is inhibited by SOCS-3 in human renal tubule cells.

Loeschenberger B, Niess L, Würzner R, Schwelberger H, Eder IE, Puhr M, Guenther J, Troppmair J, Rudnicki M, Neuwirt H.

Eur J Immunol. 2018 Feb;48(2):330-343. doi: 10.1002/eji.201747135. Epub 2017 Dec 11.

10.

RNA cytosine methyltransferase Nsun3 regulates embryonic stem cell differentiation by promoting mitochondrial activity.

Trixl L, Amort T, Wille A, Zinni M, Ebner S, Hechenberger C, Eichin F, Gabriel H, Schoberleitner I, Huang A, Piatti P, Nat R, Troppmair J, Lusser A.

Cell Mol Life Sci. 2018 Apr;75(8):1483-1497. doi: 10.1007/s00018-017-2700-0. Epub 2017 Nov 4.

11.

Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer.

Cato L, Neeb A, Sharp A, Buzón V, Ficarro SB, Yang L, Muhle-Goll C, Kuznik NC, Riisnaes R, Nava Rodrigues D, Armant O, Gourain V, Adelmant G, Ntim EA, Westerling T, Dolling D, Rescigno P, Figueiredo I, Fauser F, Wu J, Rottenberg JT, Shatkina L, Ester C, Luy B, Puchta H, Troppmair J, Jung N, Bräse S, Strähle U, Marto JA, Nienhaus GU, Al-Lazikani B, Salvatella X, de Bono JS, Cato AC, Brown M.

Elife. 2017 Aug 10;6. pii: e27159. doi: 10.7554/eLife.27159.

12.

Predicting the future from the past: volatile markers for respiratory infections.

Filipiak W, Ager C, Troppmair J.

Eur Respir J. 2017 May 25;49(5). pii: 1700264. doi: 10.1183/13993003.00264-2017. Print 2017 May. No abstract available.

13.

Novel Insights into the PKCβ-dependent Regulation of the Oxidoreductase p66Shc.

Haller M, Khalid S, Kremser L, Fresser F, Furlan T, Hermann M, Guenther J, Drasche A, Leitges M, Giorgio M, Baier G, Lindner H, Troppmair J.

J Biol Chem. 2016 Nov 4;291(45):23557-23568. Epub 2016 Sep 13.

14.

Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.

Hatzl S, Geiger O, Kuepper MK, Caraffini V, Seime T, Furlan T, Nussbaumer E, Wieser R, Pichler M, Scheideler M, Nowek K, Jongen-Lavrencic M, Quehenberger F, Wölfler A, Troppmair J, Sill H, Zebisch A.

Cancer Res. 2016 Jun 15;76(12):3644-54. doi: 10.1158/0008-5472.CAN-15-3049. Epub 2016 Apr 15.

15.

A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines.

Filipiak W, Mochalski P, Filipiak A, Ager C, Cumeras R, Davis CE, Agapiou A, Unterkofler K, Troppmair J.

Curr Med Chem. 2016;23(20):2112-31. Review.

16.

The Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ.

Papadakis ES, Barker CR, Syed H, Reeves T, Schwaiger S, Stuppner H, Troppmair J, Blaydes JP, Cutress RI.

Oncogenesis. 2016 Apr 4;5:e215. doi: 10.1038/oncsis.2016.10.

17.

A combination of trastuzumab and BAG-1 inhibition synergistically targets HER2 positive breast cancer cells.

Papadakis E, Robson N, Yeomans A, Bailey S, Laversin S, Beers S, Sayan AE, Ashton-Key M, Schwaiger S, Stuppner H, Troppmair J, Packham G, Cutress R.

Oncotarget. 2016 Apr 5;7(14):18851-64. doi: 10.18632/oncotarget.7944.

18.

cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation.

Khalid S, Drasche A, Thurner M, Hermann M, Ashraf MI, Fresser F, Baier G, Kremser L, Lindner H, Troppmair J.

Sci Rep. 2016 Feb 12;6:20930. doi: 10.1038/srep20930.

19.

Biopsychronology: A Method Using Live Tissue Staining to Image Cell Function in the Kidney.

Ashraf MI, Fries D, Streif W, Aigner F, Hengster P, Troppmair J, Hermann M.

Methods Mol Biol. 2016;1397:81-90. doi: 10.1007/978-1-4939-3353-2_8.

PMID:
26676129
20.

Breath analysis for in vivo detection of pathogens related to ventilator-associated pneumonia in intensive care patients: a prospective pilot study.

Filipiak W, Beer R, Sponring A, Filipiak A, Ager C, Schiefecker A, Lanthaler S, Helbok R, Nagl M, Troppmair J, Amann A.

J Breath Res. 2015 Jan 5;9(1):016004. doi: 10.1088/1752-7155/9/1/016004.

PMID:
25557917
21.

Precursors for cytochrome P450 profiling breath tests from an in silico screening approach.

von Grafenstein S, Fuchs JE, Huber MM, Bassi A, Lacetera A, Ruzsanyi V, Troppmair J, Amann A, Liedl KR.

J Breath Res. 2014 Sep 18;8(4):046001. doi: 10.1088/1752-7155/8/4/046001.

PMID:
25233885
22.

Comparative analyses of volatile organic compounds (VOCs) from patients, tumors and transformed cell lines for the validation of lung cancer-derived breath markers.

Filipiak W, Filipiak A, Sponring A, Schmid T, Zelger B, Ager C, Klodzinska E, Denz H, Pizzini A, Lucciarini P, Jamnig H, Troppmair J, Amann A.

J Breath Res. 2014 Jun;8(2):027111. doi: 10.1088/1752-7155/8/2/027111. Epub 2014 May 27.

PMID:
24862102
23.

Biopsychronology: live confocal imaging of biopsies to assess organ function.

Ashraf MI, Fries D, Streif W, Aigner F, Hengster P, Troppmair J, Hermann M.

Transpl Int. 2014 Aug;27(8):868-76. doi: 10.1111/tri.12338. Epub 2014 Jun 17.

24.

Bilirubin rinse of the graft ameliorates ischemia reperfusion injury in heart transplantation.

Bösch F, Thomas M, Kogler P, Oberhuber R, Sucher R, Aigner F, Semsroth S, Wiedemann D, Yamashita K, Troppmair J, Kotsch K, Pratschke J, Öllinger R.

Transpl Int. 2014 May;27(5):504-13. doi: 10.1111/tri.12278. Epub 2014 Mar 5.

25.

A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury.

Ashraf MI, Ebner M, Wallner C, Haller M, Khalid S, Schwelberger H, Koziel K, Enthammer M, Hermann M, Sickinger S, Soleiman A, Steger C, Vallant S, Sucher R, Brandacher G, Santer P, Dragun D, Troppmair J.

Cell Commun Signal. 2014 Jan 14;12:6. doi: 10.1186/1478-811X-12-6.

26.

Isolation of a novel thioflavin S-derived compound that inhibits BAG-1-mediated protein interactions and targets BRAF inhibitor-resistant cell lines.

Enthammer M, Papadakis ES, Salomé Gachet M, Deutsch M, Schwaiger S, Koziel K, Ashraf MI, Khalid S, Wolber G, Packham G, Cutress RI, Stuppner H, Troppmair J.

Mol Cancer Ther. 2013 Nov;12(11):2400-14. doi: 10.1158/1535-7163.MCT-13-0142. Epub 2013 Sep 18.

27.

RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins.

Koziel K, Smigelskaite J, Drasche A, Enthammer M, Ashraf MI, Khalid S, Troppmair J.

Exp Cell Res. 2013 Oct 15;319(17):2728-38. doi: 10.1016/j.yexcr.2013.07.029. Epub 2013 Aug 7.

28.

Release and uptake of volatile organic compounds by human hepatocellular carcinoma cells (HepG2) in vitro.

Mochalski P, Sponring A, King J, Unterkofler K, Troppmair J, Amann A.

Cancer Cell Int. 2013 Jul 17;13(1):72. doi: 10.1186/1475-2867-13-72.

29.

Lipocalin-2 as mediator of chemokine expression and granulocyte infiltration during ischemia and reperfusion.

Sickinger S, Maier H, König S, Vallant N, Kofler M, Schumpp P, Schwelberger H, Hermann M, Obrist P, Schneeberger S, Margreiter R, Troppmair J, Pratschke J, Aigner F.

Transpl Int. 2013 Jul;26(7):761-9. doi: 10.1111/tri.12116. Epub 2013 May 23.

30.

Characterization of volatile metabolites taken up by or released from Streptococcus pneumoniae and Haemophilus influenzae by using GC-MS.

Filipiak W, Sponring A, Baur MM, Ager C, Filipiak A, Wiesenhofer H, Nagl M, Troppmair J, Amann A.

Microbiology. 2012 Dec;158(Pt 12):3044-53. doi: 10.1099/mic.0.062687-0. Epub 2012 Oct 11.

PMID:
23059976
31.

Protein kinase C inhibition ameliorates posttransplantation preservation injury in rat renal transplants.

Fuller TF, Kusch A, Chaykovska L, Catar R, Pützer J, Haller M, Troppmair J, Hoff U, Dragun D.

Transplantation. 2012 Oct 15;94(7):679-86. doi: 10.1097/TP.0b013e318265c4d8.

PMID:
22932117
32.

Molecular analysis of volatile metabolites released specifically by Staphylococcus aureus and Pseudomonas aeruginosa.

Filipiak W, Sponring A, Baur MM, Filipiak A, Ager C, Wiesenhofer H, Nagl M, Troppmair J, Amann A.

BMC Microbiol. 2012 Jun 20;12:113. doi: 10.1186/1471-2180-12-113.

33.

Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia.

Zebisch A, Wölfler A, Fried I, Wolf O, Lind K, Bodner C, Haller M, Drasche A, Pirkebner D, Matallanas D, Rath O, Blyth K, Delwel R, Taskesen E, Quehenberger F, Kolch W, Troppmair J, Sill H.

Leukemia. 2012 Aug;26(8):1842-9. doi: 10.1038/leu.2012.61. Epub 2012 Mar 5.

PMID:
22388727
34.

Mitochondrial dysfunction and biogenesis: do ICU patients die from mitochondrial failure?

Kozlov AV, Bahrami S, Calzia E, Dungel P, Gille L, Kuznetsov AV, Troppmair J.

Ann Intensive Care. 2011 Sep 26;1(1):41. doi: 10.1186/2110-5820-1-41.

35.

Mitochondrial ROS production under cellular stress: comparison of different detection methods.

Kuznetsov AV, Kehrer I, Kozlov AV, Haller M, Redl H, Hermann M, Grimm M, Troppmair J.

Anal Bioanal Chem. 2011 Jun;400(8):2383-90. doi: 10.1007/s00216-011-4764-2. Epub 2011 Feb 20.

PMID:
21336935
36.

Analysis of volatile organic compounds (VOCs) in the headspace of NCI-H1666 lung cancer cells.

Sponring A, Filipiak W, Ager C, Schubert J, Miekisch W, Amann A, Troppmair J.

Cancer Biomark. 2010;7(3):153-61. doi: 10.3233/CBM-2010-0182.

PMID:
21263191
37.

Cold ischemia contributes to the development of chronic rejection and mitochondrial injury after cardiac transplantation.

Schneeberger S, Amberger A, Mandl J, Hautz T, Renz O, Obrist P, Meusburger H, Brandacher G, Mark W, Strobl D, Troppmair J, Pratschke J, Margreiter R, Kuznetsov AV.

Transpl Int. 2010 Dec;23(12):1282-92. doi: 10.1111/j.1432-2277.2010.01126.x.

38.

TD-GC-MS analysis of volatile metabolites of human lung cancer and normal cells in vitro.

Filipiak W, Sponring A, Filipiak A, Ager C, Schubert J, Miekisch W, Amann A, Troppmair J.

Cancer Epidemiol Biomarkers Prev. 2010 Jan;19(1):182-95. doi: 10.1158/1055-9965.EPI-09-0162.

39.

Intracellular signaling pathways control mitochondrial events associated with the development of ischemia/ reperfusion-associated damage.

Sucher R, Gehwolf P, Kaier T, Hermann M, Maglione M, Oberhuber R, Ratschiller T, Kuznetsov AV, Bösch F, Kozlov AV, Ashraf MI, Schneeberger S, Brandacher G, Ollinger R, Margreiter R, Troppmair J.

Transpl Int. 2009 Sep;22(9):922-30. doi: 10.1111/j.1432-2277.2009.00883.x. Epub 2009 Apr 28.

40.

Complex patterns of mitochondrial dynamics in human pancreatic cells revealed by fluorescent confocal imaging.

Kuznetsov AV, Hermann M, Troppmair J, Margreiter R, Hengster P.

J Cell Mol Med. 2010 Jan;14(1-2):417-25. doi: 10.1111/j.1582-4934.2009.00750.x. Epub 2009 Mar 27.

41.

Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations.

Zebisch A, Haller M, Hiden K, Goebel T, Hoefler G, Troppmair J, Sill H.

Leukemia. 2009 Jun;23(6):1049-53. doi: 10.1038/leu.2009.68. Epub 2009 Apr 9.

PMID:
19357705
42.

Release of volatile organic compounds from the lung cancer cell line NCI-H2087 in vitro.

Sponring A, Filipiak W, Mikoviny T, Ager C, Schubert J, Miekisch W, Amann A, Troppmair J.

Anticancer Res. 2009 Jan;29(1):419-26.

43.

Everolimus attenuates neointimal hyperplasia in cultured human saphenous vein grafts.

Semsroth S, Stigler RG, Bernecker OY, Ruttmann-Ulmer E, Troppmair J, Macfelda K, Bonatti JO, Laufer G.

Eur J Cardiothorac Surg. 2009 Mar;35(3):515-20. doi: 10.1016/j.ejcts.2008.11.035. Epub 2009 Jan 23.

PMID:
19167904
44.

Release of volatile organic compounds (VOCs) from the lung cancer cell line CALU-1 in vitro.

Filipiak W, Sponring A, Mikoviny T, Ager C, Schubert J, Miekisch W, Amann A, Troppmair J.

Cancer Cell Int. 2008 Nov 24;8:17. doi: 10.1186/1475-2867-8-17.

45.

Cytoplasmic signaling in the control of mitochondrial uproar?

Hermann M, Kuznetsov A, Maglione M, Smigelskaite J, Margreiter R, Troppmair J.

Cell Commun Signal. 2008 Aug 19;6:4. doi: 10.1186/1478-811X-6-4.

46.

Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance.

McCubrey JA, Abrams SL, Ligresti G, Misaghian N, Wong EW, Steelman LS, Bäsecke J, Troppmair J, Libra M, Nicoletti F, Molton S, McMahon M, Evangelisti C, Martelli AM.

Leukemia. 2008 Nov;22(11):2080-90. doi: 10.1038/leu.2008.207. Epub 2008 Aug 7.

PMID:
18685611
47.

Proliferation arrest in B-Raf mutant melanoma cell lines upon MAPK pathway activation.

Houben R, Ortmann S, Drasche A, Troppmair J, Herold MJ, Becker JC.

J Invest Dermatol. 2009 Feb;129(2):406-14. doi: 10.1038/jid.2008.214. Epub 2008 Jul 24.

48.

Increase of MCP-1 (CCL2) in myelin mutant Schwann cells is mediated by MEK-ERK signaling pathway.

Fischer S, Weishaupt A, Troppmair J, Martini R.

Glia. 2008 Jun;56(8):836-43. doi: 10.1002/glia.20657.

PMID:
18383340
49.

The effect of secretory leukocyte protease inhibitor (SLPI) on ischemia/reperfusion injury in cardiac transplantation.

Schneeberger S, Hautz T, Wahl SM, Brandacher G, Sucher R, Steinmassl O, Steinmassl P, Wright CD, Obrist P, Werner ER, Mark W, Troppmair J, Margreiter R, Amberger A.

Am J Transplant. 2008 Apr;8(4):773-82. doi: 10.1111/j.1600-6143.2008.02158.x. Epub 2008 Feb 19.

50.

Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway.

Hoffmann E, Ashouri J, Wolter S, Doerrie A, Dittrich-Breiholz O, Schneider H, Wagner EF, Troppmair J, Mackman N, Kracht M.

J Biol Chem. 2008 May 2;283(18):12120-8. doi: 10.1074/jbc.M800583200. Epub 2008 Feb 15.

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