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Truncating variants in UBAP1 associated with childhood-onset nonsyndromic hereditary spastic paraplegia.

Gu S, Chen CA, Rosenfeld JA, Cope H, Launay N, Flanigan K, Waldrop M, Schrader R, Juusola J; Undiagnosed Diseases Network, Goker-Alpan O, Milunsky A, Schlüter A, Troncoso M, Pujol A, Tan QKG, Schaaf CP, Meng L.

Hum Mutat. 2019 Nov 7. doi: 10.1002/humu.23950. [Epub ahead of print]


Obstructive sleep apnea and nocturnal hypoxemia are associated with an increased risk of lung cancer.

Seijo LM, Pérez-Warnisher MT, Giraldo-Cadavid LF, Oliveros H, Cabezas E, Troncoso MF, Gómez T, Melchor R, Pinillos EJ, El Hachem A, Gotera C, Rodriguez P, González-Mangado N, Peces-Barba G.

Sleep Med. 2019 Jun 6;63:41-45. doi: 10.1016/j.sleep.2019.05.011. [Epub ahead of print]


Monocular nystagmus in a patient with alternating hemiplegia of childhood.

Tello J, Ruiz I, Herrera L, Miranda A, Alid P, Troncoso M.

Neurology. 2019 Aug 20;93(8):361. doi: 10.1212/WNL.0000000000007977. No abstract available.


Upcoming Scenarios for the Comprehensive Management of Obstructive Sleep Apnea: An Overview of the Spanish Sleep Network.

Mediano O, Cano-Pumarega I, Sánchez-de-la-Torre M, Alonso-Álvarez ML, Troncoso MF, García-Río F, Egea C; Spanish Sleep Network; Spanish Sleep Network.

Arch Bronconeumol. 2019 Aug 5. pii: S0300-2896(19)30273-X. doi: 10.1016/j.arbres.2019.05.017. [Epub ahead of print] English, Spanish.


CD8+ T-cells negatively regulate inflammation post-myocardial infarction.

Ilatovskaya DV, Pitts C, Clayton J, Domondon M, Troncoso M, Pippin S, DeLeon-Pennell KY.

Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H581-H596. doi: 10.1152/ajpheart.00112.2019. Epub 2019 Jul 19.


Effect of continuous positive airway pressure on inflammatory, antioxidant, and depression biomarkers in women with obstructive sleep apnea: a randomized controlled trial.

Campos-Rodriguez F, Asensio-Cruz MI, Cordero-Guevara J, Jurado-Gamez B, Carmona-Bernal C, Gonzalez-Martinez M, Troncoso MF, Sanchez-Lopez V, Arellano-Orden E, Garcia-Sanchez MI, Martinez-Garcia MA; Spanish Sleep Network .

Sleep. 2019 Oct 9;42(10). pii: zsz145. doi: 10.1093/sleep/zsz145.


Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver.

Bacigalupo ML, Piazza VG, Cicconi NS, Carabias P, Bartke A, Fang Y, Sotelo AI, Rabinovich GA, Troncoso MF, Miquet JG.

Endocr Connect. 2019 Aug 1;8(8):1108-1117. doi: 10.1530/EC-19-0292.


MicroRNAs contribute to ATP-binding cassette transporter- and autophagy-mediated chemoresistance in hepatocellular carcinoma.

Espelt MV, Bacigalupo ML, Carabias P, Troncoso MF.

World J Hepatol. 2019 Apr 27;11(4):344-358. doi: 10.4254/wjh.v11.i4.344. Review.


GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication.

Garrido-Moreno V, Díaz-Vegas A, López-Crisosto C, Troncoso MF, Navarro-Marquez M, García L, Estrada M, Cifuentes M, Lavandero S.

Pharmacol Res. 2019 Aug;146:104273. doi: 10.1016/j.phrs.2019.104273. Epub 2019 May 13.


Long-term clinical effectiveness of continuous positive airway pressure therapy versus non-invasive ventilation therapy in patients with obesity hypoventilation syndrome: a multicentre, open-label, randomised controlled trial.

Masa JF, Mokhlesi B, Benítez I, Gomez de Terreros FJ, Sánchez-Quiroga MÁ, Romero A, Caballero-Eraso C, Terán-Santos J, Alonso-Álvarez ML, Troncoso MF, González M, López-Martín S, Marin JM, Martí S, Díaz-Cambriles T, Chiner E, Egea C, Barca J, Vázquez-Polo FJ, Negrín MA, Martel-Escobar M, Barbe F, Corral J; Spanish Sleep Network.

Lancet. 2019 Apr 27;393(10182):1721-1732. doi: 10.1016/S0140-6736(18)32978-7. Epub 2019 Mar 29.


Dual knockdown of Galectin-8 and its glycosylated ligand, the activated leukocyte cell adhesion molecule (ALCAM/CD166), synergistically delays in vivo breast cancer growth.

Ferragut F, Cagnoni AJ, Colombo LL, Sánchez Terrero C, Wolfenstein-Todel C, Troncoso MF, Vanzulli SI, Rabinovich GA, Mariño KV, Elola MT.

Biochim Biophys Acta Mol Cell Res. 2019 Aug;1866(8):1338-1352. doi: 10.1016/j.bbamcr.2019.03.010. Epub 2019 Mar 21.


Ultrasound-Guided Extraction of Intrauterine Devices With Nonvisible Threads: 254 Consecutive Cases: An Effective, Noninvasive Technique.

Kottmann C, Troncoso M, Valenzuela I, Ugarte C, Diaz P, Monckeberg M, Illanes SE.

J Ultrasound Med. 2019 Nov;38(11):3073-3077. doi: 10.1002/jum.14986. Epub 2019 Mar 18.


Community Engagement in the Development of an mHealth-Enabled Physical Activity and Cardiovascular Health Intervention (Step It Up): Pilot Focus Group Study.

Ceasar JN, Claudel SE, Andrews MR, Tamura K, Mitchell V, Brooks AT, Dodge T, El-Toukhy S, Farmer N, Middleton K, Sabado-Liwag M, Troncoso M, Wallen GR, Powell-Wiley TM.

JMIR Form Res. 2019 Jan 4;3(1):e10944. doi: 10.2196/10944.


Sleep disordered breathing and nocturnal hypoxemia are very prevalent in a lung cancer screening population and may condition lung cancer screening findings: results of the prospective Sleep Apnea In Lung Cancer Screening (SAILS) study.

Pérez-Warnisher MT, Cabezas E, Troncoso MF, Gómez T, Melchor R, Pinillos EJ, El Hachem A, Gotera C, Rodriguez P, Mahíllo I, González-Mangado N, Peces-Barba G, Seijo LM.

Sleep Med. 2019 Feb;54:181-186. doi: 10.1016/j.sleep.2018.10.020. Epub 2018 Nov 3.


Continuous Positive Airway Pressure Treatment Does not Reduce Uric Acid Levels in OSA Women.

Campos-Rodriguez F, Reyes-Nuñez N, Queipo-Corona C, Sanchez-Armengol A, Jurado-Gamez B, Cordero-Guevara J, Troncoso MF, Abad-Fernandez A, Caballero-Rodriguez J, Martin-Romero M, Encabo-Motiño A, Sacristan-Bou L, Navarro-Esteva J, Somoza-Gonzalez M, Masa JF, Sanchez-Quiroga MA, Jara-Chinarro B, Orosa-Bertol B, Martinez-Garcia MA; Spanish Sleep Network; Spanish Sleep Network is composed of the following individuals.

Arch Bronconeumol. 2019 Apr;55(4):201-207. doi: 10.1016/j.arbres.2018.09.012. Epub 2018 Nov 14. English, Spanish.


Hypoxia-ischemia alters distribution of lysosomal proteins in rat cortex and hippocampus.

Troncoso M, Bannoud N, Carvelli L, Asensio J, Seltzer A, Sosa MA.

Biol Open. 2018 Oct 25;7(10). pii: bio036723. doi: 10.1242/bio.036723.


Sleep Disordered Breathing Is Highly Prevalent in Patients with Lung Cancer: Results of the Sleep Apnea in Lung Cancer Study.

Cabezas E, Pérez-Warnisher MT, Troncoso MF, Gómez T, Melchor R, Pinillos EJ, El Hachem A, Gotera C, Rodríguez P, Mahillo Fernández I, Martínez-García MÁ; González-Mangado, Peces-Barba G, Seijo LM.

Respiration. 2019;97(2):119-124. doi: 10.1159/000492273. Epub 2018 Sep 27.


Antimicrobial effect of copper surfaces on bacteria isolated from poultry meat.

Parra A, Toro M, Jacob R, Navarrete P, Troncoso M, Figueroa G, Reyes-Jara A.

Braz J Microbiol. 2018 Nov;49 Suppl 1:113-118. doi: 10.1016/j.bjm.2018.06.008. Epub 2018 Aug 24.


Cation-dependent mannose-6-phosphate receptor expression and distribution are influenced by estradiol in MCF-7 breast cancer cells.

Bannoud N, Carvelli FL, Troncoso M, Sartor T, Vargas-Roig LM, Sosa M.

PLoS One. 2018 Aug 7;13(8):e0201844. doi: 10.1371/journal.pone.0201844. eCollection 2018.


Evaluating the Capacity of Human Gut Microorganisms to Colonize the Zebrafish Larvae (Danio rerio).

Valenzuela MJ, Caruffo M, Herrera Y, Medina DA, Coronado M, Feijóo CG, Muñoz S, Garrido D, Troncoso M, Figueroa G, Toro M, Reyes-Jara A, Magne F, Navarrete P.

Front Microbiol. 2018 May 29;9:1032. doi: 10.3389/fmicb.2018.01032. eCollection 2018.


GDF11 Modulates Ca2+-Dependent Smad2/3 Signaling to Prevent Cardiomyocyte Hypertrophy.

Duran J, Troncoso MF, Lagos D, Ramos S, Marin G, Estrada M.

Int J Mol Sci. 2018 May 18;19(5). pii: E1508. doi: 10.3390/ijms19051508.


Biomarkers of carcinogenesis and tumour growth in patients with cutaneous melanoma and obstructive sleep apnoea.

Santamaria-Martos F, Benítez I, Girón C, Barbé F, Martínez-García MA, Hernández L, Montserrat JM, Nagore E, Martorell A, Campos-Rodriguez F, Corral J, Cabriada V, Abad J, Mediano O, Troncoso MF, Cano-Pumarega I, Fortuna Gutierrez AM, Diaz-Cambriles T, Somoza-Gonzalez M, Almendros I, Farre R, Gozal D, Sánchez-de-la-Torre M; Spanish Sleep Network.

Eur Respir J. 2018 Mar 15;51(3). pii: 1701885. doi: 10.1183/13993003.01885-2017. Print 2018 Mar.


Differences in BMI between Mexican and Colombian patients receiving antipsychotics: results from the International Study of Latinos on Antipsychotics (ISLA).

Ng B, Camacho A, Parra K, de la Espriella R, Rico V, Lozano S, Troncoso M, Castilla-Puentes RC, Cook BL, Jimenez DE.

Ethn Health. 2018 Mar 7:1-8. doi: 10.1080/13557858.2018.1439894. [Epub ahead of print]


Ca2+/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy.

Duran J, Lagos D, Pavez M, Troncoso MF, Ramos S, Barrientos G, Ibarra C, Lavandero S, Estrada M.

Front Pharmacol. 2017 Sep 11;8:604. doi: 10.3389/fphar.2017.00604. eCollection 2017.


[Treatment of hyperthyroidism with radioiodine during hemodialysis: Report of one case].

Hurtado C, Báez MS, Bate A, Opazo C, Troncoso M.

Rev Med Chil. 2017 May;145(5):673-677. doi: 10.4067/S0034-98872017000500017. Spanish.


Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression.

Bacigalupo ML, Carabias P, Troncoso MF.

World J Gastroenterol. 2017 Aug 7;23(29):5266-5281. doi: 10.3748/wjg.v23.i29.5266. Review.


Effect of continuous positive airway pressure on blood pressure and metabolic profile in women with sleep apnoea.

Campos-Rodriguez F, Gonzalez-Martinez M, Sanchez-Armengol A, Jurado-Gamez B, Cordero-Guevara J, Reyes-Nuñez N, Troncoso MF, Abad-Fernandez A, Teran-Santos J, Caballero-Rodriguez J, Martin-Romero M, Encabo-Motiño A, Sacristan-Bou L, Navarro-Esteva J, Somoza-Gonzalez M, Masa JF, Sanchez-Quiroga MA, Jara-Chinarro B, Orosa-Bertol B, Martinez-Garcia MA; Spanish Sleep Network.

Eur Respir J. 2017 Aug 10;50(2). pii: 1700257. doi: 10.1183/13993003.00257-2017. Print 2017 Aug.


Lesch-Nyhan disease in two families from Chiloé Island with mutations in the HPRT1 gene.

Nguyen KV, Silva S, Troncoso M, Naviaux RK, Nyhan WL.

Nucleosides Nucleotides Nucleic Acids. 2017 Jul 3;36(7):452-462. doi: 10.1080/15257770.2017.1315434. Epub 2017 May 19.


[Clinical and genetic study patients with tuberous sclerosis complex].

Rubilar C, López F, Troncoso M, Barrios A, Herrera L.

Rev Chil Pediatr. 2017 Feb;88(1):41-49. doi: 10.1016/j.rchipe.2016.08.003. Spanish.


GSK-3β/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy.

Duran J, Oyarce C, Pavez M, Valladares D, Basualto-Alarcon C, Lagos D, Barrientos G, Troncoso MF, Ibarra C, Estrada M.

PLoS One. 2016 Dec 15;11(12):e0168255. doi: 10.1371/journal.pone.0168255. eCollection 2016.


Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/phagocytosis and oligodendroglial differentiation.

Rinaldi M, Thomas L, Mathieu P, Carabias P, Troncoso MF, Pasquini JM, Rabinovich GA, Pasquini LA.

Neurobiol Dis. 2016 Dec;96:127-143. doi: 10.1016/j.nbd.2016.09.003. Epub 2016 Sep 6.


Neurotoxins from Clostridium botulinum (serotype A) isolated from the soil of Mendoza (Argentina) differ from the A-Hall archetype and from that causing infant botulism.

Caballero P, Troncoso M, Patterson SI, López Gómez C, Fernandez R, Sosa MA.

Toxicon. 2016 Oct;121:30-35. doi: 10.1016/j.toxicon.2016.08.010. Epub 2016 Aug 13.


Non-invasive ventilation in obesity hypoventilation syndrome without severe obstructive sleep apnoea.

Masa JF, Corral J, Caballero C, Barrot E, Terán-Santos J, Alonso-Álvarez ML, Gomez-Garcia T, González M, López-Martín S, De Lucas P, Marin JM, Marti S, Díaz-Cambriles T, Chiner E, Egea C, Miranda E, Mokhlesi B; Spanish Sleep Network, García-Ledesma E, Sánchez-Quiroga MÁ, Ordax E, González-Mangado N, Troncoso MF, Martinez-Martinez MÁ, Cantalejo O, Ojeda E, Carrizo SJ, Gallego B, Pallero M, Ramón MA, Díaz-de-Atauri J, Muñoz-Méndez J, Senent C, Sancho-Chust JN, Ribas-Solís FJ, Romero A, Benítez JM, Sanchez-Gómez J, Golpe R, Santiago-Recuerda A, Gomez S, Bengoa M.

Thorax. 2016 Oct;71(10):899-906. doi: 10.1136/thoraxjnl-2016-208501. Epub 2016 Jul 12.


Antibacterial Effect of Copper on Microorganisms Isolated from Bovine Mastitis.

Reyes-Jara A, Cordero N, Aguirre J, Troncoso M, Figueroa G.

Front Microbiol. 2016 Apr 28;7:626. doi: 10.3389/fmicb.2016.00626. eCollection 2016.


Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells.

Fernández MM, Ferragut F, Cárdenas Delgado VM, Bracalente C, Bravo AI, Cagnoni AJ, Nuñez M, Morosi LG, Quinta HR, Espelt MV, Troncoso MF, Wolfenstein-Todel C, Mariño KV, Malchiodi EL, Rabinovich GA, Elola MT.

Biochim Biophys Acta. 2016 Oct;1860(10):2255-68. doi: 10.1016/j.bbagen.2016.04.019. Epub 2016 Apr 26.


Mid- and Long-Term Efficacy of Non-Invasive Ventilation in Obesity Hypoventilation Syndrome: The Pickwick's Study.

López-Jiménez MJ, Masa JF, Corral J, Terán J, Ordaz E, Troncoso MF, González-Mangado N, González M, Lopez-Martínez S, De Lucas P, Marín JM, Martí S, Díaz-Cambriles T, Díaz-de-Atauri J, Chiner E, Aizpuru F, Egea C, Romero A, Benítez JM, Sánchez-Gómez J, Golpe R, Santiago-Recuerda A, Gómez S, Barbe F, Bengoa M; Grupo cooperativo.

Arch Bronconeumol. 2016 Mar;52(3):158-65. doi: 10.1016/j.arbres.2015.10.003. Epub 2015 Dec 4. English, Spanish.


Galectin-1 Controls the Proliferation and Migration of Liver Sinusoidal Endothelial Cells and Their Interaction With Hepatocarcinoma Cells.

Manzi M, Bacigalupo ML, Carabias P, Elola MT, Wolfenstein-Todel C, Rabinovich GA, Espelt MV, Troncoso MF.

J Cell Physiol. 2016 Jul;231(7):1522-33. doi: 10.1002/jcp.25244. Epub 2015 Nov 26.


Efficacy of Different Treatment Alternatives for Obesity Hypoventilation Syndrome. Pickwick Study.

Masa JF, Corral J, Alonso ML, Ordax E, Troncoso MF, Gonzalez M, Lopez-Martínez S, Marin JM, Marti S, Díaz-Cambriles T, Chiner E, Aizpuru F, Egea C; Spanish Sleep Network.

Am J Respir Crit Care Med. 2015 Jul 1;192(1):86-95. doi: 10.1164/rccm.201410-1900OC.


[Complex febrile Seizures or Dravet syndrome?: Description of 3 case reports].

Hernández M, Pedraza M, Mesa T, Troncoso M.

Rev Chil Pediatr. 2014 Oct;85(5):588-93. doi: 10.4067/S0370-41062014000500010. Spanish.


The phenotypic spectrum of SCN8A encephalopathy.

Larsen J, Carvill GL, Gardella E, Kluger G, Schmiedel G, Barisic N, Depienne C, Brilstra E, Mang Y, Nielsen JE, Kirkpatrick M, Goudie D, Goldman R, Jähn JA, Jepsen B, Gill D, Döcker M, Biskup S, McMahon JM, Koeleman B, Harris M, Braun K, de Kovel CG, Marini C, Specchio N, Djémié T, Weckhuysen S, Tommerup N, Troncoso M, Troncoso L, Bevot A, Wolff M, Hjalgrim H, Guerrini R, Scheffer IE, Mefford HC, Møller RS; EuroEPINOMICS RES Consortium CRP.

Neurology. 2015 Feb 3;84(5):480-9. doi: 10.1212/WNL.0000000000001211. Epub 2015 Jan 7.


Galectin-1 triggers epithelial-mesenchymal transition in human hepatocellular carcinoma cells.

Bacigalupo ML, Manzi M, Espelt MV, Gentilini LD, Compagno D, Laderach DJ, Wolfenstein-Todel C, Rabinovich GA, Troncoso MF.

J Cell Physiol. 2015 Jun;230(6):1298-309. doi: 10.1002/jcp.24865.


Effectiveness of home single-channel nasal pressure for sleep apnea diagnosis.

Masa JF, Duran-Cantolla J, Capote F, Cabello M, Abad J, Garcia-Rio F, Ferrer A, Mayos M, Gonzalez-Mangado N, de la Peña M, Aizpuru F, Barbe F, Montserrat JM; Spanish Sleep Network, Larrateguy LD, de Castro JR, Garcia-Ledesma E, Utrabo I, Corral J, Martinez-Null C, Egea C, Cancelo L, García-Díaz E, Carmona-Bernal C, Sánchez-Armengol A, Fortuna AM, Miralda RM, Troncoso MF, Monica G, Martinez-Martinez M, Cantalejo O, Piérola J, Vigil L, Embid C, Del Mar Centelles M, Prieto TR, Rojo B, Vanesa L.

Sleep. 2014 Dec 1;37(12):1953-61. doi: 10.5665/sleep.4248.


Galectin-8: a matricellular lectin with key roles in angiogenesis.

Troncoso MF, Ferragut F, Bacigalupo ML, Cárdenas Delgado VM, Nugnes LG, Gentilini L, Laderach D, Wolfenstein-Todel C, Compagno D, Rabinovich GA, Elola MT.

Glycobiology. 2014 Oct;24(10):907-14. doi: 10.1093/glycob/cwu054. Epub 2014 Jun 16. Review.


Expression, localization and function of galectin-8, a tandem-repeat lectin, in human tumors.

Elola MT, Ferragut F, Cárdenas Delgado VM, Nugnes LG, Gentilini L, Laderach D, Troncoso MF, Compagno D, Wolfenstein-Todel C, Rabinovich GA.

Histol Histopathol. 2014 Sep;29(9):1093-105. doi: 10.14670/HH-29.1093. Epub 2014 Mar 31. Review.


Probiotic screening and safety evaluation of Lactobacillus strains from plants, artisanal goat cheese, human stools, and breast milk.

Gotteland M, Cires MJ, Carvallo C, Vega N, Ramirez MA, Morales P, Rivas P, Astudillo F, Navarrete P, Dubos C, Figueroa A, Troncoso M, Ulloa C, Mizgier ML, Carrasco-Pozo C, Speisky H, Brunser O, Figueroa G.

J Med Food. 2014 Apr;17(4):487-95. doi: 10.1089/jmf.2013.0030. Epub 2014 Jan 16.


Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma.

Bacigalupo ML, Manzi M, Rabinovich GA, Troncoso MF.

World J Gastroenterol. 2013 Dec 21;19(47):8831-49. doi: 10.3748/wjg.v19.i47.8831. Review.


[Premature birth in patient with cervix incompetence and history of myasthenia gravis].

Fuentealba M, Troncoso M, Vallejos J, Ponce S, Villablanca N, Melita P.

Ginecol Obstet Mex. 2013 Sep;81(9):545-9. Spanish.


Fingerprinting-based metabolomic approach with LC-MS to sleep apnea and hypopnea syndrome: a pilot study.

Ferrarini A, Rupérez FJ, Erazo M, Martínez MP, Villar-Álvarez F, Peces-Barba G, González-Mangado N, Troncoso MF, Ruiz-Cabello J, Barbas C.

Electrophoresis. 2013 Oct;34(19):2873-81. doi: 10.1002/elps.201300081. Epub 2013 Aug 16.


Neuronal ceroid lipofuscinosis type CLN2: a new rationale for the construction of phenotypic subgroups based on a survey of 25 cases in South America.

Kohan R, Carabelos MN, Xin W, Sims K, Guelbert N, Cismondi IA, Pons P, Alonso GI, Troncoso M, Witting S, Pearce DA, Dodelson de Kremer R, Oller-Ramírez AM, Noher de Halac I.

Gene. 2013 Mar 1;516(1):114-21. doi: 10.1016/j.gene.2012.12.058. Epub 2012 Dec 22.


Mutant huntingtin affects endocytosis in striatal cells by altering the binding of AP-2 to membranes.

Borgonovo JE, Troncoso M, Lucas JJ, Sosa MA.

Exp Neurol. 2013 Mar;241:75-83. doi: 10.1016/j.expneurol.2012.11.025. Epub 2012 Dec 5.


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