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Items: 12

1.

In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs.

Juvonen RO, Heikkinen AT, Kärkkäinen O, Jehangir R, Huuskonen J, Troberg J, Raunio H, Pentikäinen OT, Finel M.

Eur J Pharm Sci. 2019 Oct 25;141:105118. doi: 10.1016/j.ejps.2019.105118. [Epub ahead of print]

PMID:
31669387
2.

Data on biosynthesis of BPAF glucuronide, enzyme kinetics of BPAF glucuronidation, and molecular modeling.

Gramec Skledar D, Trontelj J, Troberg J, Tomašič T, Zega A, Finel M, Peterlin Mašič L.

Data Brief. 2018 Dec 17;22:977-986. doi: 10.1016/j.dib.2018.12.033. eCollection 2019 Feb.

3.

Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite.

Skledar DG, Carino A, Trontelj J, Troberg J, Distrutti E, Marchianò S, Tomašič T, Zega A, Finel M, Fiorucci S, Mašič LP.

Chemosphere. 2019 Jan;215:870-880. doi: 10.1016/j.chemosphere.2018.10.129. Epub 2018 Oct 18.

PMID:
30408883
4.

Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10.

Juvonen RO, Rauhamäki S, Kortet S, Niinivehmas S, Troberg J, Petsalo A, Huuskonen J, Raunio H, Finel M, Pentikäinen OT.

Mol Pharm. 2018 Mar 5;15(3):923-933. doi: 10.1021/acs.molpharmaceut.7b00871. Epub 2018 Feb 15.

5.

Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.

Järvinen E, Troberg J, Kidron H, Finel M.

Mol Pharm. 2017 Oct 2;14(10):3299-3311. doi: 10.1021/acs.molpharmaceut.7b00366. Epub 2017 Sep 13.

PMID:
28850245
6.

Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation.

He G, Troberg J, Lv X, Xia YL, Zhu LL, Ning J, Ge GB, Finel M, Yang L.

Xenobiotica. 2018 Feb;48(2):109-116. doi: 10.1080/00498254.2017.1283719. Epub 2017 Jul 25.

PMID:
28689454
7.

UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?

Troberg J, Järvinen E, Ge GB, Yang L, Finel M.

Mol Pharm. 2017 Sep 5;14(9):2875-2883. doi: 10.1021/acs.molpharmaceut.6b00852. Epub 2016 Dec 14.

PMID:
27966992
8.

The Polymorphic Variant P24T of UDP-Glucuronosyltransferase 1A4 and Its Unusual Consequences.

Troberg J, Finel M.

Drug Metab Dispos. 2015 Nov;43(11):1769-72. doi: 10.1124/dmd.115.065680. Epub 2015 Sep 1.

PMID:
26329791
9.

An optimized ratiometric fluorescent probe for sensing human UDP-glucuronosyltransferase 1A1 and its biological applications.

Lv X, Ge GB, Feng L, Troberg J, Hu LH, Hou J, Cheng HL, Wang P, Liu ZM, Finel M, Cui JN, Yang L.

Biosens Bioelectron. 2015 Oct 15;72:261-7. doi: 10.1016/j.bios.2015.05.003. Epub 2015 May 8.

PMID:
25988789
10.

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

Gramec Skledar D, Troberg J, Lavdas J, Peterlin Mašič L, Finel M.

Xenobiotica. 2015;45(6):511-9. doi: 10.3109/00498254.2014.999140. Epub 2014 Dec 30.

PMID:
25547628
11.

Dog UDP-glucuronosyltransferase enzymes of subfamily 1A: cloning, expression, and activity.

Troberg J, Järvinen E, Muniz M, Sneitz N, Mosorin J, Hagström M, Finel M.

Drug Metab Dispos. 2015 Jan;43(1):107-18. doi: 10.1124/dmd.114.059303. Epub 2014 Oct 9.

PMID:
25301937
12.

Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent.

Manevski N, Troberg J, Svaluto-Moreolo P, Dziedzic K, Yli-Kauhaluoma J, Finel M.

PLoS One. 2013;8(1):e54767. doi: 10.1371/journal.pone.0054767. Epub 2013 Jan 23.

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